Notch signaling induces apoptosis in primary human CD34+ hematopoietic progenitor cells

Stem Cells

Volumn 25, Issue 1, 2007, Pages 203-210

  Chadwick, Nicholas ^a   Nostro, Maria Cristina ^b   Baron, Martin ^a   Mottram, Rachel ^a   Brady, Gerard ^b   Buckle, Anne Marie ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b Epistem Ltd   (United Kingdom)

Author keywords

Hematopoiesis; Notch; Stem cell

Indexed keywords

GAMMA SECRETASE INHIBITOR; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PROTEIN BCL X; PROTEIN NOTCH 1 INTRACELLULAR DOMAIN; PROTEIN P21; TRANSCRIPTION FACTOR HES 1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CD34 SELECTION; CELL CYCLE ARREST; CELL FATE; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; GENE AMPLIFICATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN EXPRESSION; UPREGULATION;

ANTIGENS, CD34; APOPTOSIS; CELL CYCLE; CELL SEPARATION; COCULTURE TECHNIQUES; DNA, COMPLEMENTARY; GENES, REPORTER; HEMATOPOIETIC STEM CELLS; HUMANS; LUCIFERASES; POLYMERASE CHAIN REACTION; RECEPTORS, NOTCH; RETROVIRIDAE; STROMAL CELLS; TRANSDUCTION, GENETIC;

MURINAE;

EID: 33846003463     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0303     Document Type: Article

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