메뉴 건너뛰기




Volumn 73, Issue 3, 2010, Pages 116-123

Obesity and asthma: Co-morbidity or causal relationship?

Author keywords

Asthma; Metabolic syndrome; Obesity; Systemic inflammation

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; INTERLEUKIN 6; LEPTIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 78649815542     PISSN: 11220643     EISSN: 2465101X     Source Type: Journal    
DOI: 10.4081/monaldi.2010.295     Document Type: Review
Times cited : (14)

References (76)
  • 1
    • 34249011025 scopus 로고    scopus 로고
    • Organisation WH cited; Available from
    • Organisation WH. Obesity and overweight, fact sheet No 311. 2006 [cited; Available from: http://www.who.int/mediacentre/factsheets/fs311/en/print.html
    • (2006) Obesity and Overweight, Fact Sheet No 311
  • 2
    • 76149090843 scopus 로고    scopus 로고
    • Changes in the prevalence of asthma in adults since 1966: The Busselton health study
    • James AL, Knuiman MW, et al. Changes in the prevalence of asthma in adults since 1966: the Busselton health study. Eur Respir J 2010; 35: 273-8.
    • (2010) Eur Respir J , vol.35 , pp. 273-278
    • James, A.L.1    Knuiman, M.W.2
  • 3
    • 68949198770 scopus 로고    scopus 로고
    • Atopy, obesity, and asthma in adults: The Humboldt study
    • Chen Y, Rennie D, Cormier Y, Dosman J. Atopy, obesity, and asthma in adults: the Humboldt study. J Agromed 2009; 14: 222-7.
    • (2009) J Agromed , vol.14 , pp. 222-227
    • Chen, Y.1    Rennie, D.2    Cormier, Y.3    Dosman, J.4
  • 5
    • 34047214102 scopus 로고    scopus 로고
    • Overweight, obesity, and incident asthma: A meta-analysis of prospective epidemiologic studies
    • Beuther DA, Sutherland ER. Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies. Am J Respir Crit Care Med 2007; 175: 661-6.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 661-666
    • Beuther, D.A.1    Sutherland, E.R.2
  • 6
    • 0344065387 scopus 로고    scopus 로고
    • Prospective study of body mass index, weight change, and risk of adult-onset asthma in women
    • Camargo CA, Jr., Weiss ST, Zhang S, Willett WC, Speizer FE. Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med 1999; 159: 2582-8.
    • (1999) Arch Intern Med , vol.159 , pp. 2582-2588
    • Camargo Jr., C.A.1    Weiss, S.T.2    Zhang, S.3    Willett, W.C.4    Speizer, F.E.5
  • 7
    • 33344462192 scopus 로고    scopus 로고
    • Higher BMI is associated with worse asthma control and quality of life but not asthma severity
    • DOI 10.1016/j.rmed.2005.08.001, PII S0954611105002982
    • Lavoie KL, Bacon SL, Labrecque M, Cartier A, Ditto B. Higher BMI is associated with worse asthma control and quality of life but not asthma severity. Respir Med 2006; 100: 648-57. (Pubitemid 43285752)
    • (2006) Respiratory Medicine , vol.100 , Issue.4 , pp. 648-657
    • Lavoie, K.L.1    Bacon, S.L.2    Labrecque, M.3    Cartier, A.4    Ditto, B.5
  • 9
    • 67651213554 scopus 로고    scopus 로고
    • Does higher body mass index contribute to worse asthma control in an urban population?
    • Clerisme-Beaty EM, Karam S, et al. Does higher body mass index contribute to worse asthma control in an urban population? J Allergy Clin Immunol 2009; 124: 207-12.
    • (2009) J Allergy Clin Immunol , vol.124 , pp. 207-212
    • Clerisme-Beaty, E.M.1    Karam, S.2
  • 11
    • 4444246466 scopus 로고    scopus 로고
    • Relationship between asthma severity and obesity
    • Akerman MJ, Calacanis CM, Madsen MK. Relationship between asthma severity and obesity. J Asthma 2004; 41: 521-6.
    • (2004) J Asthma , vol.41 , pp. 521-526
    • Akerman, M.J.1    Calacanis, C.M.2    Madsen, M.K.3
  • 14
    • 77949596686 scopus 로고    scopus 로고
    • Does obesity produce a distinct asthma phenotype?
    • Mar
    • Lugogo NL, Kraft M, Dixon AE. Does obesity produce a distinct asthma phenotype? J Appl Physiol 2010 Mar; 108: 729-34.
    • (2010) J Appl Physiol , vol.108 , pp. 729-734
    • Lugogo, N.L.1    Kraft, M.2    Dixon, A.E.3
  • 16
    • 25844452675 scopus 로고    scopus 로고
    • No significant relationship between exhaled nitric oxide and body mass index in people with asthma
    • author reply 30
    • Kazaks A, Uriu-Adams JY, Stern JS, Albertson TE. No significant relationship between exhaled nitric oxide and body mass index in people with asthma. J Allergy Clin Immunol 2005; 116: 929-30; author reply 30.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 929-930
    • Kazaks, A.1    Uriu-Adams, J.Y.2    Stern, J.S.3    Albertson, T.E.4
  • 17
    • 34250746427 scopus 로고    scopus 로고
    • Effect of obesity on airway inflammation: A cross-sectional analysis of body mass index and sputum cell counts
    • Todd DC, Armstrong S, D'Silva L, Allen CJ, Hargreave FE, Parameswaran K. Effect of obesity on airway inflammation: a cross-sectional analysis of body mass index and sputum cell counts. Clin Exp Allergy 2007; 37: 1049-54.
    • (2007) Clin Exp Allergy , vol.37 , pp. 1049-1054
    • Todd, D.C.1    Armstrong, S.2    D'Silva, L.3    Allen, C.J.4    Hargreave, F.E.5    Parameswaran, K.6
  • 18
    • 51349125818 scopus 로고    scopus 로고
    • The association between obesity and asthma: Interactions between systemic and airway inflammation
    • Sutherland TJ, Cowan JO, Young S, et al. The association between obesity and asthma: interactions between systemic and airway inflammation. Am J Respir Crit Care Med 2008; 178: 469-75.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 469-475
    • Sutherland, T.J.1    Cowan, J.O.2    Young, S.3
  • 19
    • 41749115987 scopus 로고    scopus 로고
    • Airway inflammation in obese and nonobese patients with difficult-to-treat asthma
    • van Veen IH, Ten Brinke A, Sterk PJ, Rabe KF, Bel EH. Airway inflammation in obese and nonobese patients with difficult-to-treat asthma. Allergy 2008; 63: 570-4.
    • (2008) Allergy , vol.63 , pp. 570-574
    • Van Veen, I.H.1    Ten Brinke, A.2    Sterk, P.J.3    Rabe, K.F.4    Bel, E.H.5
  • 21
    • 20144387976 scopus 로고    scopus 로고
    • Sex differences in the relation between body mass index and asthma and atopy in a birth cohort
    • Hancox RJ, Milne BJ, Poulton R, et al. Sex differences in the relation between body mass index and asthma and atopy in a birth cohort. Am J Respir Crit Care Med 2005; 171: 440-5.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 440-445
    • Hancox, R.J.1    Milne, B.J.2    Poulton, R.3
  • 22
    • 0347291904 scopus 로고    scopus 로고
    • Asthma and atopy in overweight children
    • Schachter LM, Peat JK, Salome CM. Asthma and atopy in overweight children. Thorax 2003; 58: 1031-5.
    • (2003) Thorax , vol.58 , pp. 1031-1035
    • Schachter, L.M.1    Peat, J.K.2    Salome, C.M.3
  • 23
    • 33748846563 scopus 로고    scopus 로고
    • The association between obesity and asthma is stronger in nonallergic than allergic adults
    • Chen Y, Dales R, Jiang Y. The association between obesity and asthma is stronger in nonallergic than allergic adults. Chest 2006; 130: 890-5.
    • (2006) Chest , vol.130 , pp. 890-895
    • Chen, Y.1    Dales, R.2    Jiang, Y.3
  • 24
    • 0036286387 scopus 로고    scopus 로고
    • Association of body mass index with respiratory symptoms and atopy: Results from the European Community Respiratory Health Survey
    • DOI 10.1046/j.1365-2222.2002.01380.x
    • Jarvis D, Chinn S, Potts J, Burney P. Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey. Clin Exp Allergy 2002; 32: 831-7. (Pubitemid 34626078)
    • (2002) Clinical and Experimental Allergy , vol.32 , Issue.6 , pp. 831-837
    • Jarvis, D.1    Chinn, S.2    Potts, J.3    Burney, P.4
  • 25
    • 40949120616 scopus 로고    scopus 로고
    • Obesity and adult asthma: Potential effect modification by gender, but not by hay fever
    • Loerbroks A, Apfelbacher CJ, Amelang M, Sturmer T. Obesity and adult asthma: potential effect modification by gender, but not by hay fever. Ann Epidemiol 2008; 18: 283-9.
    • (2008) Ann Epidemiol , vol.18 , pp. 283-289
    • Loerbroks, A.1    Apfelbacher, C.J.2    Amelang, M.3    Sturmer, T.4
  • 26
    • 77953574259 scopus 로고    scopus 로고
    • Effect of increased body mass index on asthma risk, impairment and response to asthma controller therapy in African Americans
    • Camargo CA, Jr., Sutherland ER, Bailey W, et al. Effect of increased body mass index on asthma risk, impairment and response to asthma controller therapy in African Americans. Curr Med Res Opin 26: 1629-35.
    • Curr Med Res Opin , vol.26 , pp. 1629-1635
    • Camargo Jr., C.A.1    Sutherland, E.R.2    Bailey, W.3
  • 27
    • 67649160039 scopus 로고    scopus 로고
    • Body mass index and phenotype in subjects with mild-to-moderate persistent asthma
    • e1
    • Sutherland ER, Lehman EB, Teodorescu M, Wechsler ME. Body mass index and phenotype in subjects with mild-to-moderate persistent asthma. J Allergy Clin Immunol 2009; 123: 1328-34 e1.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 1328-1334
    • Sutherland, E.R.1    Lehman, E.B.2    Teodorescu, M.3    Wechsler, M.E.4
  • 28
    • 76149115897 scopus 로고    scopus 로고
    • Body mass index and response to asthma therapy: Fluticasone propionate/salmeterol versus montelukast
    • Camargo CA, Jr., Boulet LP, Sutherland ER, et al. Body mass index and response to asthma therapy: fluticasone propionate/salmeterol versus montelukast. J Asthma 47: 76-82.
    • J Asthma , vol.47 , pp. 76-82
    • Camargo Jr., C.A.1    Boulet, L.P.2    Sutherland, E.R.3
  • 29
    • 2942733178 scopus 로고    scopus 로고
    • Effect of weight reduction on respiratory function and airway reactivity in obese women
    • Aaron SD, Fergusson D, Dent R, Chen Y, Vandemheen KL, Dales RE. Effect of weight reduction on respiratory function and airway reactivity in obese women. Chest 2004; 125: 2046-52.
    • (2004) Chest , vol.125 , pp. 2046-2052
    • Aaron, S.D.1    Fergusson, D.2    Dent, R.3    Chen, Y.4    Vandemheen, K.L.5    Dales, R.E.6
  • 30
    • 0034712563 scopus 로고    scopus 로고
    • Immediate and long term effects of weight reduction in obese people with asthma: Randomised controlled study
    • Stenius-Aarniala B, Poussa T, Kvarnstrom J, Gronlund EL, Ylikahri M, Mustajoki P. Immediate and long term effects of weight reduction in obese people with asthma: randomised controlled study. BMJ 2000; 320 (7238): 827-32.
    • (2000) BMJ , vol.320 , Issue.7238 , pp. 827-832
    • Stenius-Aarniala, B.1    Poussa, T.2    Kvarnstrom, J.3    Gronlund, E.L.4    Ylikahri, M.5    Mustajoki, P.6
  • 31
    • 49149106673 scopus 로고    scopus 로고
    • Weight loss and asthma: A systematic review
    • Eneli IU, Skybo T, Camargo CA, Jr. Weight loss and asthma: a systematic review. Thorax 2008; 63: 671-6.
    • (2008) Thorax , vol.63 , pp. 671-676
    • Eneli, I.U.1    Skybo, T.2    Camargo Jr., C.A.3
  • 32
    • 0032837773 scopus 로고    scopus 로고
    • Marked improvement in asthma after Lap-Band surgery for morbid obesity
    • Dixon JB, Chapman L, O'Brien P. Marked improvement in asthma after Lap-Band surgery for morbid obesity. Obesity Surg 1999; 9: 385-9.
    • (1999) Obesity Surg , vol.9 , pp. 385-389
    • Dixon, J.B.1    Chapman, L.2    O'Brien, P.3
  • 33
    • 0033728998 scopus 로고    scopus 로고
    • Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma
    • Hakala K, Stenius-Aarniala B, Sovijarvi A. Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma. Chest 2000; 118: 1315-21.
    • (2000) Chest , vol.118 , pp. 1315-1321
    • Hakala, K.1    Stenius-Aarniala, B.2    Sovijarvi, A.3
  • 34
    • 62949241099 scopus 로고    scopus 로고
    • Improvement of restrictive and obstructive pulmonary mechanics following laparoscopic bariatric surgery
    • Nguyen NT, Hinojosa MW, Smith BR, Gray J, Varela E. Improvement of restrictive and obstructive pulmonary mechanics following laparoscopic bariatric surgery. Surg Endosc 2009; 23: 808-12.
    • (2009) Surg Endosc , vol.23 , pp. 808-812
    • Nguyen, N.T.1    Hinojosa, M.W.2    Smith, B.R.3    Gray, J.4    Varela, E.5
  • 35
    • 20644443064 scopus 로고    scopus 로고
    • Obesity: Insight into the origins of asthma
    • Weiss ST. Obesity: insight into the origins of asthma. Nature Immunology 2005; 6: 537-9.
    • (2005) Nature Immunology , vol.6 , pp. 537-539
    • Weiss, S.T.1
  • 36
    • 0034847353 scopus 로고    scopus 로고
    • Complex interactions in complex traits: Obesity and asthma
    • Tantisira KG, Weiss ST. Complex interactions in complex traits: obesity and asthma. Thorax 2001; 56 Suppl 2: ii64-73.
    • (2001) Thorax , vol.56 , Issue.SUPPL. 2
    • Tantisira, K.G.1    Weiss, S.T.2
  • 38
    • 33646541672 scopus 로고    scopus 로고
    • Effects of esomeprazole 40 mg twice daily on asthma: A randomized placebo-controlled trial
    • Kiljander TO, Harding SM, Field SK, et al. Effects of esomeprazole 40 mg twice daily on asthma: a randomized placebo-controlled trial. Am J Respir Crit Care Med 2006; 173: 1091-7.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 1091-1097
    • Kiljander, T.O.1    Harding, S.M.2    Field, S.K.3
  • 39
    • 67651218965 scopus 로고    scopus 로고
    • Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma
    • Julien JY, Martin JG, Ernst P, et al. Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma. J Allergy Clin Immunol 2009; 124: 371-6.
    • (2009) J Allergy Clin Immunol , vol.124 , pp. 371-376
    • Julien, J.Y.1    Martin, J.G.2    Ernst, P.3
  • 40
    • 3843142681 scopus 로고    scopus 로고
    • Obesity and nocturnal gastro-oesophageal reflux are related to onset of asthma and respiratory symptoms
    • Gunnbjornsdottir MI, Omenaas E, Gislason T, et al. Obesity and nocturnal gastro-oesophageal reflux are related to onset of asthma and respiratory symptoms. Eur Respir J 2004; 24: 116-21.
    • (2004) Eur Respir J , vol.24 , pp. 116-121
    • Gunnbjornsdottir, M.I.1    Omenaas, E.2    Gislason, T.3
  • 42
    • 73949119670 scopus 로고    scopus 로고
    • Physiology of obesity and effects on lung function
    • Salome CM, King GG, Berend N. Physiology of obesity and effects on lung function. J Appl Physiol 2010; 108: 206-11.
    • (2010) J Appl Physiol , vol.108 , pp. 206-211
    • Salome, C.M.1    King, G.G.2    Berend, N.3
  • 43
    • 68849128511 scopus 로고    scopus 로고
    • Obesity and asthma
    • viii
    • Beuther DA. Obesity and asthma. Clinic Chest Med 2009; 30: 479-88, viii.
    • (2009) Clinic Chest Med , vol.30 , pp. 479-488
    • Beuther, D.A.1
  • 44
    • 0031957232 scopus 로고    scopus 로고
    • Influence of excessive weight loss after gastroplasty for morbid obesity on respiratory muscle performance
    • Weiner P, Waizman J, Weiner M, Rabner M, Magadle R, Zamir D. Influence of excessive weight loss after gastroplasty for morbid obesity on respiratory muscle performance. Thorax 1998; 53: 39-42.
    • (1998) Thorax , vol.53 , pp. 39-42
    • Weiner, P.1    Waizman, J.2    Weiner, M.3    Rabner, M.4    Magadle, R.5    Zamir, D.6
  • 46
    • 40949125258 scopus 로고    scopus 로고
    • Effect of obesity on breathlessness and airway responsiveness to methacholine in non-asthmatic subjects
    • Salome CM, Munoz PA, Berend N, Thorpe CW, Schachter LM, King GG. Effect of obesity on breathlessness and airway responsiveness to methacholine in non-asthmatic subjects. Intern J Obesity 2008; 32: 502-9.
    • (2008) Intern J Obesity , vol.32 , pp. 502-509
    • Salome, C.M.1    Munoz, P.A.2    Berend, N.3    Thorpe, C.W.4    Schachter, L.M.5    King, G.G.6
  • 47
    • 74949131555 scopus 로고    scopus 로고
    • Effects of Obesity on Perceptual and Mechanical Responses to Bronchoconstriction in Asthma
    • Deesomchok A, Fisher T, Webb KA, et al. Effects of Obesity on Perceptual and Mechanical Responses to Bronchoconstriction in Asthma. Am J Respir Crit Care Med 2010; 181: 125-33.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 125-133
    • Deesomchok, A.1    Fisher, T.2    Webb, K.A.3
  • 48
    • 33644911756 scopus 로고    scopus 로고
    • The endocrine function of adipose tissue: An update
    • Ronti T, Lupattelli G, Mannarino E. The endocrine function of adipose tissue: an update. Clin Endocrinol 2006; 64: 355-65.
    • (2006) Clin Endocrinol , vol.64 , pp. 355-365
    • Ronti, T.1    Lupattelli, G.2    Mannarino, E.3
  • 49
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • New York, NY
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science (New York, NY) 1993; 259 (5091): 87-91.
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 50
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation- Induced immunosuppression
    • DOI 10.1038/29795
    • Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 1998; 394 (6696): 897-901. (Pubitemid 28410912)
    • (1998) Nature , vol.394 , Issue.6696 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3    Baker, R.J.4    Bloom, S.R.5    Lechler, R.I.6
  • 51
    • 13344295079 scopus 로고    scopus 로고
    • Serum immunoreactive-leptin concentrations in normal-weight and obese humans
    • Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. New Emgl J Med 1996; 334: 292-5.
    • (1996) New Emgl J Med , vol.334 , pp. 292-295
    • Considine, R.V.1    Sinha, M.K.2    Heiman, M.L.3
  • 52
    • 0034119354 scopus 로고    scopus 로고
    • Hyperleptinemia is more closely associated with adipose cell hypertrophy than with adipose tissue hyperplasia
    • Couillard C, Mauriege P, Imbeault P, et al. Hyperleptinemia is more closely associated with adipose cell hypertrophy than with adipose tissue hyperplasia. Int J Obes Relat Metab Disord 2000; 24: 782-8.
    • (2000) Int J Obes Relat Metab Disord , vol.24 , pp. 782-788
    • Couillard, C.1    Mauriege, P.2    Imbeault, P.3
  • 54
    • 11144337173 scopus 로고    scopus 로고
    • Leptin and asthma in overweight children at 12 years of age
    • Mai XM, Bottcher MF, Leijon I. Leptin and asthma in overweight children at 12 years of age. Pediatr Allergy Immunol 2004; 15: 523-30.
    • (2004) Pediatr Allergy Immunol , vol.15 , pp. 523-530
    • Mai, X.M.1    Bottcher, M.F.2    Leijon, I.3
  • 55
    • 0042466384 scopus 로고    scopus 로고
    • Regulation of adiponectin by adipose tissue-derived cytokines: In vivo and in vitro investigations in humans
    • Bruun JM, Lihn AS, Verdich C, et al. Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans. Am J Physiol Endocrinol Metab 2003; 285: E527-33.
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Bruun, J.M.1    Lihn, A.S.2    Verdich, C.3
  • 56
    • 0037380664 scopus 로고    scopus 로고
    • Association between adiponectin and mediators of inflammation in obese women
    • Engeli S, Feldpausch M, Gorzelniak K, et al. Association between adiponectin and mediators of inflammation in obese women. Diabetes 2003; 52: 942-7.
    • (2003) Diabetes , vol.52 , pp. 942-947
    • Engeli, S.1    Feldpausch, M.2    Gorzelniak, K.3
  • 59
    • 53649093993 scopus 로고    scopus 로고
    • Association between asthma and serum adiponectin concentration in women
    • Sood A, Cui X, Quails C, et al. Association between asthma and serum adiponectin concentration in women. Thorax 2008; 63: 877-82.
    • (2008) Thorax , vol.63 , pp. 877-882
    • Sood, A.1    Cui, X.2    Quails, C.3
  • 60
    • 63849150014 scopus 로고    scopus 로고
    • Obesity, adipokines and asthma
    • Jartti T, Saarikoski L, Jartti L, et al. Obesity, adipokines and asthma. Allergy 2009; 64: 770-7.
    • (2009) Allergy , vol.64 , pp. 770-777
    • Jartti, T.1    Saarikoski, L.2    Jartti, L.3
  • 61
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H, Barnes GT, Yang Q, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003; 112: 1821-30.
    • (2003) J Clin Invest , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 63
    • 0035985534 scopus 로고    scopus 로고
    • Effect of surgically-induced weight loss on leukocyte indicators of chronic inflammation in morbid obesity
    • Cottam DR, Schaefer PA, Shaftan GW, Velcu L, Angus LD. Effect of surgically-induced weight loss on leukocyte indicators of chronic inflammation in morbid obesity. Obes surg 2002; 12: 335-42.
    • (2002) Obes Surg , vol.12 , pp. 335-342
    • Cottam, D.R.1    Schaefer, P.A.2    Shaftan, G.W.3    Velcu, L.4    Angus, L.D.5
  • 64
    • 0037840403 scopus 로고    scopus 로고
    • Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: A randomized trial
    • Esposito K, Pontillo A, Di Palo C, et al. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. JAMA 2003; 289: 1799-804.
    • (2003) JAMA , vol.289 , pp. 1799-1804
    • Esposito, K.1    Pontillo, A.2    Di Palo, C.3
  • 65
    • 0033678516 scopus 로고    scopus 로고
    • Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss
    • Bastard JP, Jardel C, Bruckert E, et al. Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss. J Clin Endocrinol Metab 2000; 85: 3338-42.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3338-3342
    • Bastard, J.P.1    Jardel, C.2    Bruckert, E.3
  • 66
    • 63249135843 scopus 로고    scopus 로고
    • Lung function impairment and metabolic syndrome: The critical role of abdominal obesity
    • Leone N, Courbon D, Thomas F, et al. Lung function impairment and metabolic syndrome: the critical role of abdominal obesity. Am J Respir Crit Care Med 2009; 179: 509-16.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 509-516
    • Leone, N.1    Courbon, D.2    Thomas, F.3
  • 67
    • 67649830897 scopus 로고    scopus 로고
    • Asthma-like symptoms are increased in the metabolic syndrome
    • Lee EJ, In KH, Ha ES, et al. Asthma-like symptoms are increased in the metabolic syndrome. J Asthma 2009; 46: 339-42.
    • (2009) J Asthma , vol.46 , pp. 339-342
    • Lee, E.J.1    In, K.H.2    Ha, E.S.3
  • 68
    • 41749095405 scopus 로고    scopus 로고
    • Association of obesity and insulin resistance with asthma and aeroallergen sensitization
    • Husemoen LL, Glumer C, Lau C, Pisinger C, Morch LS, Linneberg A. Association of obesity and insulin resistance with asthma and aeroallergen sensitization. Allergy 2008; 63: 575-82.
    • (2008) Allergy , vol.63 , pp. 575-582
    • Husemoen, L.L.1    Glumer, C.2    Lau, C.3    Pisinger, C.4    Morch, L.S.5    Linneberg, A.6
  • 70
    • 55449096455 scopus 로고    scopus 로고
    • No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice
    • Shore SA, Williams ES, Zhu M. No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice. J Appl Physiol 2008; 105: 1127-33.
    • (2008) J Appl Physiol , vol.105 , pp. 1127-1133
    • Shore, S.A.1    Williams, E.S.2    Zhu, M.3
  • 71
    • 65449158021 scopus 로고    scopus 로고
    • Body mass index-percentile and diagnostic accuracy of childhood asthma
    • Lang JE, Feng H, Lima JJ. Body mass index-percentile and diagnostic accuracy of childhood asthma. J Asthma 2009; 46: 291-9.
    • (2009) J Asthma , vol.46 , pp. 291-299
    • Lang, J.E.1    Feng, H.2    Lima, J.J.3
  • 72
    • 56649088178 scopus 로고    scopus 로고
    • Overdiagnosis of asthma in obese and nonobese adults
    • Aaron SD, Vandemheen KL, Boulet LP, et al. Overdiagnosis of asthma in obese and nonobese adults. Can Med Ass J 2008; 179: 1121-31.
    • (2008) Can Med Ass J , vol.179 , pp. 1121-1131
    • Aaron, S.D.1    Vandemheen, K.L.2    Boulet, L.P.3
  • 73
    • 77953302599 scopus 로고    scopus 로고
    • A comparison of obese and nonobese asthmatics: Exploring an asthma-obesity interaction
    • Pakhale S, Doucette S, Vandemheen K, et al. A comparison of obese and nonobese asthmatics: Exploring an asthma-obesity interaction. Chest 2010; 137: 1316-23.
    • (2010) Chest , vol.137 , pp. 1316-1323
    • Pakhale, S.1    Doucette, S.2    Vandemheen, K.3
  • 74
    • 34250682264 scopus 로고    scopus 로고
    • A comparison of direct vs. self-report measures for assessing height, weight and body mass index: A systematic review
    • Gorber SC, Tremblay M, Moher D, Gorber B. A comparison of direct vs. self-report measures for assessing height, weight and body mass index: a systematic review. Obes Rev 2007; 8: 307-26.
    • (2007) Obes Rev , vol.8 , pp. 307-326
    • Gorber, S.C.1    Tremblay, M.2    Moher, D.3    Gorber, B.4
  • 75
    • 0035044502 scopus 로고    scopus 로고
    • The effect of gender on the relationship between body fat distribution and lung function
    • Harik-Khan RI, Wise RA, Fleg JL. The effect of gender on the relationship between body fat distribution and lung function. J Clin Epidemiol 2001; 54: 399-406.
    • (2001) J Clin Epidemiol , vol.54 , pp. 399-406
    • Harik-Khan, R.I.1    Wise, R.A.2    Fleg, J.L.3
  • 76
    • 60849124545 scopus 로고    scopus 로고
    • Obesity is associated with altered lung function independently of physical activity and fitness
    • Steele RM, Finucane FM, Griffin SJ, Wareham NJ, Ekelund U. Obesity is associated with altered lung function independently of physical activity and fitness. Obesity 2009; 17: 578-84.
    • (2009) Obesity , vol.17 , pp. 578-584
    • Steele, R.M.1    Finucane, F.M.2    Griffin, S.J.3    Wareham, N.J.4    Ekelund, U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.