Leptin, adiponectin, and asthma: Findings from a population-based cohort study

Annals of Allergy, Asthma and Immunology

Volumn 103, Issue 2, 2009, Pages 101-107

  Sutherland, Tim J T ^a   Sears, Malcolm R ^b   McLachlan, Christene R ^a   Poulton, Richie ^a   Hancox, Robert J ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; BIOLOGICAL MARKER; LEPTIN; NITRIC OXIDE; SALBUTAMOL;

ADULT; AIRWAY OBSTRUCTION; ARTICLE; ASTHMA; BODY FAT; BRONCHODILATATION; BRONCHUS REACTIVITY; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; EVALUATION; FEMALE; HUMAN; LINEAR REGRESSION ANALYSIS; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; OBESITY; PHENOTYPE; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SMOKING; WHEEZING;

ADIPONECTIN; ADULT; ASTHMA; BREATH TESTS; BRONCHIAL PROVOCATION TESTS; COHORT STUDIES; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LEPTIN; MALE; NEW ZEALAND; NITRIC OXIDE; OBESITY; RESPIRATORY SOUNDS; SEX CHARACTERISTICS; SMOKING; VITAL CAPACITY;

EID: 68249087354     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/S1081-1206(10)60161-5     Document Type: Article

References (39)

1. Beuther DA, Weiss ST, Sutherland ER. Obesity and asthma. Am J Respir Crit Care Med. 2006;174:112-119.
2. Shore SA. Obesity and asthma: possible mechanisms. J Allergy Clin Immunol. 2008;121:1087-1093.
3. Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol. 2005;115:911-919; quiz, 920.
4. Tantisira KG, Weiss ST. Complex interactions in complex traits: obesity and asthma. Thorax. 2001;56(suppl 2):ii64-ii73.
5. Shore SA. Obesity and asthma: cause for concern. Curr Opin Pharmacol. 2006;6:230-236.
6. Fruhbeck G, Jebb SA, Prentice AM. Leptin: physiology and pathophysiology. Clin Physiol. 1998;18:399-419.
7. Mastronardi CA, Walczewska A, Yu WH, Karanth S, Parlow AF, McCann SM. The possible role of prolactin in the circadian rhythm of leptin secretion in male rats. Proc Soc Exp Biol Med. 2000;224:152-158. (Pubitemid 30439070)
8. Fantuzzi G, Faggioni R. Leptin in the regulation of immunity, inflammation, and hematopoiesis. J Leukoc Biol. 2000;68:437-446. (Pubitemid 30764574)
9. Guler N, Kirerleri E, Ones U, Tamay Z, Salmayenli N, Darendeliler F. Leptin: does it have any role in childhood asthma? J Allergy Clin Immunol. 2004;114:254-259. (Pubitemid 39127423)
10. Sood A, Ford ES, Camargo CA Jr. Association between leptin and asthma in adults. Thorax. 2006;61:300-305.
11. Sin DD, Man SF. Impaired lung function and serum leptin in men and women with normal body weight: a population based study. Thorax. 2003;58:695-698.
12. Shore SA, Schwartzman IN, Mellema MS, Flynt L, Imrich A, Johnston RA. Effect of leptin on allergic airway responses in mice. J Allergy Clin Immunol. 2005;115:103-109. (Pubitemid 40075428)
13. Matsuzawa Y. Adiponectin: identification, physiology and clinical relevance in metabolic and vascular disease. Atheroscler Suppl. 2005;6: 7-14. (Pubitemid 40501304)
14. Kern PA, Di Gregorio GB, Lu T, Rassouli N, Ranganathan G. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-α expression. Diabetes. 2003;52:1779-1785. (Pubitemid 36792470)
15. Yokota T, Oritani K, Takahashi I, et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood. 2000;96:1723-1732. (Pubitemid 30661055)
16. Shore SA, Terry RD, Flynt L, Xu A, Hug C. Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice. J Allergy Clin Immunol. 2006;118:389-395. (Pubitemid 44142709)
17. Sood A, Cui X, Qualls C, et al. Association between asthma and serum adiponectin concentration in women. Thorax. 2008;63:877-882.
18. Hancox RJ, Milne BJ, Poulton R, et al. Sex differences in the relation between body mass index and asthma and atopy in a birth cohort. Am J Respir Crit Care Med. 2005;171:440-445. (Pubitemid 40444243)
19. McLachlan CR, Poulton R, Car G, et al. Adiposity, asthma, and airway inflammation. J Allergy Clin Immunol. 2007;119:634-639.
20. Silva PA, Stanton WA, ed. From Child to Adult: The Dunedin Multidisciplinary Health and Development Study. Auckland, New Zealand: Oxford University Press; 1996.
21. Sears MR, Greene JM, Willan AR, et al. A longitudinal, population-based, cohort study of childhood asthma followed to adulthood. N Engl J Med. 2003;349:1414-1422. (Pubitemid 37211056)
22. Burney P, Chinn S. Developing a new questionnaire for measuring the prevalence and distribution of asthma. Chest. 1987;91:79S-83S. (Pubitemid 17082241)
23. Ferris BG. Epidemiology Standardization Project (American Thoracic Society). Am Rev Respir Dis. 1978;118:1-120.
24. American Thoracic Society; European Respiratory Society. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med. 2005;171:912-930.
25. Smith AD, Cowan JO, Brassett KP, Herbison GP, Taylor DR. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med. 2005;352:2163-2173.
26. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J. 2005;26:319-338.
27. Beckett WS, Jacobs DR Jr, Yu X, Iribarren C, Williams OD. Asthma is associated with weight gain in females but not males, independent of physical activity. Am J Respir Crit Care Med. 2001;164:2045-2050. (Pubitemid 34020246)
28. Litonjua AA, Sparrow D, Celedon JC, DeMolles D, Weiss ST. Association of body mass index with the development of methacholine airway hyperresponsiveness in men: the Normative Aging Study. Thorax. 2002; 57:581-585. (Pubitemid 34761758)
29. Luder E, Ehrlich RI, Lou WY, Melnik TA, Kattan M. Body mass index and the risk of asthma in adults. Respir Med. 2004;98:29-37. (Pubitemid 38100752)
30. Kim KW, Shin YH, Lee KE, Kim ES, Sohn MH, Kim KE. Relationship between adipokines and manifestations of childhood asthma. Pediatr Allergy Immunol. 2008;19:535-540.
31. Nagel G, Koenig W, Rapp K, Wabitsch M, Zoellner I, Weiland SK. Associations of adipokines with asthma, rhinoconjunctivitis, and eczema in German schoolchildren. Pediatr Allergy Immunol. 2009;20:81-88.
32. Wolf AM, Wolf D, Rumpold H, Enrich B, Tilg H. Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes. Biochem Biophys Res Commun. 2004;323:630-635. (Pubitemid 39221142)
33. Shore SA. Obesity and asthma: lessons from animal models. J Appl Physiol. 2007;102:516-528. (Pubitemid 46220879)
34. Weiss ST. Obesity: insight into the origins of asthma. Nat Immunol. 2005;6:537-539.
35. Weiss ST, Shore S. Obesity and asthma: directions for research. Am J Respir Crit Care Med. 2004;169:963-968.
36. Gan WQ, Man SF, Senthilselvan A, Sin DD. Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis. Thorax. 2004;59:574-580. (Pubitemid 38901515)
37. Hancox RJ, Poulton R, Greene JM, et al. Systemic inflammation and lung function in young adults. Thorax. 2007;62:1064-1068. (Pubitemid 350206198)
38. Kony S, Zureik M, Driss F, Neukirch C, Leynaert B, Neukirch F. Association of bronchial hyperresponsiveness and lung function with C-reactive protein (CRP): a population based study. Thorax. 2004;59: 892-896. (Pubitemid 39389631)
39. Sutherland TJT, Taylor DR, Sears MR, et al. Association between exhaled nitric oxide and systemic inflammatory markers. Ann Allergy Asthma Immunol. 2007;99:334-339. (Pubitemid 47606135)