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Volumn 132, Issue 11, 2010, Pages 489-503

Botulinum toxin: Bioweapon & magic drug

Author keywords

Botulinum toxin; Botulism; Clostridium botulinum; Neurotoxin; Proteinase

Indexed keywords

ANTIBIOTIC AGENT; BABYBIG; BOTULINUM ANTISERUM; BOTULINUM TOXIN; BOTULINUM TOXIN A; BOTULINUM TOXIN B; BOTULINUM TOXOID; DNA VACCINE; MYOBLOCK; NEUROBLOCK; PENICILLIN DERIVATIVE; RECOMBINANT VACCINE; TOXOID; UNCLASSIFIED DRUG;

EID: 78649466897     PISSN: 09715916     EISSN: 09715916     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (67)

References (184)
  • 2
    • 0002462484 scopus 로고
    • Clostridium botulinum and other Clostridia that produce botulinum neurotoxins
    • In: Hauschild AHW, Dodds KL, editors. New York: Marcel Dekkar
    • Hatheway CL. Clostridium botulinum and other Clostridia that produce botulinum neurotoxins. In: Hauschild AHW, Dodds KL, editors. Clostridium botulinum: Ecology and control in foods. New York: Marcel Dekkar; 1992. p. 3-20.
    • (1992) Clostridium botulinum: Ecology and control in foods , pp. 3-20
    • Hatheway, C.L.1
  • 3
    • 37049232988 scopus 로고
    • The most poisonous poison
    • Lamanna C. The most poisonous poison. Science 1959; 130: 763-72.
    • (1959) Science , vol.130 , pp. 763-772
    • Lamanna, C.1
  • 4
    • 0343233345 scopus 로고
    • Botulism as a world health problem
    • In: Lewis KH, Kassel Jr. K, editors. Cincinnati: Ohio: U. S. Department of Health, Education, and Welfare. Public Health Service
    • Dolman CE. Botulism as a world health problem. In: Lewis KH, Kassel Jr. K, editors. Botulism. Cincinnati: Ohio: U. S. Department of Health, Education, and Welfare. Public Health Service; 1964. p. 5-32.
    • (1964) Botulism , pp. 5-32
    • Dolman, C.E.1
  • 5
    • 0002837246 scopus 로고
    • About a new anaerobic bacillus and its relationship to botulism
    • Van Ermengem, E. About a new anaerobic bacillus and its relationship to botulism. Z Hyg Infektionskr 1897; 26: 1-56.
    • (1897) Z Hyg Infektionskr , vol.26 , pp. 1-56
    • Van Ermengem, E.1
  • 6
    • 13144292220 scopus 로고
    • Studies on organisms concerned as causative factors in botulism
    • Bengston IA. Studies on organisms concerned as causative factors in botulism. Hyg Lab Bull 1924; 136: 101.
    • (1924) Hyg Lab Bull , vol.136 , pp. 101
    • Bengston, I.A.1
  • 7
    • 0029958814 scopus 로고    scopus 로고
    • Update: Infant botulism
    • Midura TF. Update: infant botulism. Clin Microbiol Rev 1996; 9: 119-25.
    • (1996) Clin Microbiol Rev , vol.9 , pp. 119-125
    • Midura, T.F.1
  • 9
    • 0029122024 scopus 로고
    • Botulism: The present status of the disease
    • Hatheway CL. Botulism: the present status of the disease. Curr Top Microbiol Immunol 1995; 195: 55-75.
    • (1995) Curr Top Microbiol Immunol , vol.195 , pp. 55-75
    • Hatheway, C.L.1
  • 10
    • 0002694157 scopus 로고
    • Botulism
    • In: Balows A, Hausler WH, Ohashi M, Turnano A, editors. New York: Berlin Heidelberg, Springer
    • Hatheway CL. Botulism. In: Balows A, Hausler WH, Ohashi M, Turnano A, editors. Laboratory diagnosis of infectious diseases: principles and practice, vol. 1. New York: Berlin Heidelberg, Springer; 1988. p. 111-33.
    • (1988) Laboratory diagnosis of infectious diseases: Principles and practice , vol.1 , pp. 111-133
    • Hatheway, C.L.1
  • 11
    • 0002049956 scopus 로고
    • Epidemiology of human foodborne botulism
    • In: Hauschild AHW, Dodds KL, editors. New York: Marcel Dekker
    • Hauschild AHW. Epidemiology of human foodborne botulism. In: Hauschild AHW, Dodds KL, editors. Clostridium botulinum. Ecology and Control in foods. New York: Marcel Dekker; 1992. p. 68-104.
    • (1992) Clostridium botulinum. Ecology and Control in foods , pp. 68-104
    • Hauschild, A.H.W.1
  • 13
    • 78649491527 scopus 로고    scopus 로고
    • Centers for Diseases Control (CDC), Atlanta: CDC, July-Aug
    • Centers for Diseases Control (CDC). Botulism associated with canned chili sauce. Atlanta: CDC; 2007 July-Aug.
    • (2007) Botulism associated with canned chili sauce
  • 14
    • 0024255967 scopus 로고
    • An outbreak of type A foodborne botulism in Taiwan due to commercially preserved peanuts
    • Chou JH, Hwant PH, Malison MD. An outbreak of type A foodborne botulism in Taiwan due to commercially preserved peanuts. Int J Epidemiol 1988; 17: 899-902.
    • (1988) Int J Epidemiol , vol.17 , pp. 899-902
    • Chou, J.H.1    Hwant, P.H.2    Malison, M.D.3
  • 15
    • 0345550445 scopus 로고    scopus 로고
    • An outbreak of foodborne botulism associated with food sold at a salvage store in Texas
    • Kalluri P, Crowe C, Reller M, Gaul L, Hayslett J, Barth S, et al. An outbreak of foodborne botulism associated with food sold at a salvage store in Texas. Clin Infect Dis 2003; 37: 1490-5.
    • (2003) Clin Infect Dis , vol.37 , pp. 1490-1495
    • Kalluri, P.1    Crowe, C.2    Reller, M.3    Gaul, L.4    Hayslett, J.5    Barth, S.6
  • 18
    • 54249145569 scopus 로고    scopus 로고
    • International outbreak of severe botulism with prolonged toxemia caused by commercial carrot juice
    • Steth AN, Wiersma P, Atrubin D, Dubey V, Zink D, Skinner G, et al. International outbreak of severe botulism with prolonged toxemia caused by commercial carrot juice. Clin Infect Dis 2008; 47: 1245-51.
    • (2008) Clin Infect Dis , vol.47 , pp. 1245-1251
    • Steth, A.N.1    Wiersma, P.2    Atrubin, D.3    Dubey, V.4    Zink, D.5    Skinner, G.6
  • 19
    • 0033553206 scopus 로고    scopus 로고
    • Outbreak of type A botulism and development of a botulism surveillance and antitoxin release system in Argentina
    • Villar RG, Shapiro RL, Busto S, Riva-Posse C, Verdejo G, Farace MI, et al. Outbreak of type A botulism and development of a botulism surveillance and antitoxin release system in Argentina. JAMA 1999; 281: 1334-8.
    • (1999) JAMA , vol.281 , pp. 1334-1338
    • Villar, R.G.1    Shapiro, R.L.2    Busto, S.3    Riva-Posse, C.4    Verdejo, G.5    Farace, M.I.6
  • 20
    • 0017130758 scopus 로고
    • Infant botulism: Identification of Clostridium botulinum and its toxin in feces
    • Midura TF, Arnon SS. Infant botulism: Identification of Clostridium botulinum and its toxin in feces. Lancet 1976; 2: 934-6.
    • (1976) Lancet , vol.2 , pp. 934-936
    • Midura, T.F.1    Arnon, S.S.2
  • 21
    • 0032145932 scopus 로고    scopus 로고
    • Botulism in the United States:A clinical and epidemiological review
    • Shapiro RL, Hatheway CL, Swerdlow DL. Botulism in the United States:A clinical and epidemiological review. Ann Intern Med 1998; 129: 221-8.
    • (1998) Ann Intern Med , vol.129 , pp. 221-228
    • Shapiro, R.L.1    Hatheway, C.L.2    Swerdlow, D.L.3
  • 22
    • 0001895002 scopus 로고    scopus 로고
    • Human tetanus and human botulism
    • In: Rood JI, McClane BA, Songer JG, Titball RW, editors. London: Academic press
    • Arnon SS. Human tetanus and human botulism. In: Rood JI, McClane BA, Songer JG, Titball RW, editors. The Clostridia: Molecular biology and pathogenesis. London: Academic press; 1997. p. 95-115.
    • (1997) The Clostridia: Molecular biology and pathogenesis , pp. 95-115
    • Arnon, S.S.1
  • 23
    • 0018316361 scopus 로고
    • Honey and other environmental risk factors for infant botulism
    • Arnon SS, Midura TF, Damus K. Honey and other environmental risk factors for infant botulism. J Pediatr 1979; 194: 331-6.
    • (1979) J Pediatr , vol.194 , pp. 331-336
    • Arnon, S.S.1    Midura, T.F.2    Damus, K.3
  • 24
    • 11844301349 scopus 로고    scopus 로고
    • Infant botulism acquired from household dust presenting as sudden infant death syndrome
    • Nevas M, Lindstrom M, Virtanen A, Hielm S, Kuusi M, Arnon SS, et al. Infant botulism acquired from household dust presenting as sudden infant death syndrome. J Clin Microbiol 2005; 43: 511-3.
    • (2005) J Clin Microbiol , vol.43 , pp. 511-513
    • Nevas, M.1    Lindstrom, M.2    Virtanen, A.3    Hielm, S.4    Kuusi, M.5    Arnon, S.S.6
  • 25
    • 47749092693 scopus 로고    scopus 로고
    • Global occurrence of infant botulism, 1976-2006
    • Koepke R, Sobel J, Arnon SS. Global occurrence of infant botulism, 1976-2006. Paediatrics 2008; 122: 73-82.
    • (2008) Paediatrics , vol.122 , pp. 73-82
    • Koepke, R.1    Sobel, J.2    Arnon, S.S.3
  • 26
    • 0032542698 scopus 로고    scopus 로고
    • Wound botulism associated with black tar heroin among injecting drug user
    • Passaro DJ, Werner SB, McGee J, MacKenzie WR, Vugia DJ. Wound botulism associated with black tar heroin among injecting drug user. JAMA 1998; 279: 859-63.
    • (1998) JAMA , vol.279 , pp. 859-863
    • Passaro, D.J.1    Werner, S.B.2    McGee, J.3    McKenzie, W.R.4    Vugia, D.J.5
  • 27
    • 22544447113 scopus 로고    scopus 로고
    • Soft tissue infections caused by spore-forming bacteria in injecting drug users in the United Kingdom
    • Brett MM, Hood J, Brazier JS, Duerden BI, Hahne SJ. Soft tissue infections caused by spore-forming bacteria in injecting drug users in the United Kingdom. Epidemiol Infect 2005; 133: 575-82.
    • (2005) Epidemiol Infect , vol.133 , pp. 575-582
    • Brett, M.M.1    Hood, J.2    Brazier, J.S.3    Duerden, B.I.4    Hahne, S.J.5
  • 30
    • 0025755407 scopus 로고
    • A comparison of human and animal botulism: A review
    • Critchley JMR. A comparison of human and animal botulism: A review. J R Soc Med 1991; 84: 295-8.
    • (1991) J R Soc Med , vol.84 , pp. 295-298
    • Critchley, J.M.R.1
  • 33
    • 0001222053 scopus 로고
    • Control in fishery products
    • In: Hauschild AHW, Dodds KL, editors. New York: Marcel Dekker
    • Eklund MW. Control in fishery products. In: Hauschild AHW, Dodds KL, editors. Clostridium botulinum. Ecology and control in foods. New York: Marcel Dekker; 1992. p. 209-32.
    • (1992) Clostridium botulinum. Ecology and control in foods , pp. 209-232
    • Eklund, M.W.1
  • 35
    • 73849176950 scopus 로고
    • Botulism caused by inhalation
    • Holzer E. Botulism caused by inhalation. Med Klin 1962; 41: 1735-40.
    • (1962) Med Klin , vol.41 , pp. 1735-1740
    • Holzer, E.1
  • 36
    • 0000643070 scopus 로고
    • Efficacy of prophylactic and therapeutic administration of antitoxin for inhalation botulism
    • In: DasGupta BR, editior. New York: Plenum Press
    • Franz DR, Pitt LM, Clayton MA, Hanes MA, Rose KJ. Efficacy of prophylactic and therapeutic administration of antitoxin for inhalation botulism. In: DasGupta BR, editior. Botulinum and tetanus Neurotoxins and Biomedical aspects. New York: Plenum Press; 1993. p. 473-6.
    • (1993) Botulinum and tetanus Neurotoxins and Biomedical aspects , pp. 473-476
    • Franz, D.R.1    Pitt, L.M.2    Clayton, M.A.3    Hanes, M.A.4    Rose, K.J.5
  • 37
    • 0037373083 scopus 로고    scopus 로고
    • Inhalational poisoning by botulinum toxin and inhalational vaccination with its heavy chain component
    • Park JB, Simpson LL. Inhalational poisoning by botulinum toxin and inhalational vaccination with its heavy chain component. Infect Immun 2003; 71: 1147-54.
    • (2003) Infect Immun , vol.71 , pp. 1147-1154
    • Park, J.B.1    Simpson, L.L.2
  • 38
    • 26444527989 scopus 로고    scopus 로고
    • Botulism
    • Sobel J. Botulism. Clin Infect Dis 2005; 4: 1167-73.
    • (2005) Clin Infect Dis , vol.4 , pp. 1167-1173
    • Sobel, J.1
  • 39
    • 33751257772 scopus 로고    scopus 로고
    • Botulism in 4 adults following cosmetic injections with an unlicensed highly concentrated botulinum preparation
    • Chertow DS, Tan ET, Maslanka SE, Schulte J, Bresnitz EA, Weisman RS, et al. Botulism in 4 adults following cosmetic injections with an unlicensed highly concentrated botulinum preparation. JAMA 2006; 296: 2476-9.
    • (2006) JAMA , vol.296 , pp. 2476-2479
    • Chertow, D.S.1    Tan, E.T.2    Maslanka, S.E.3    Schulte, J.4    Bresnitz, E.A.5    Weisman, R.S.6
  • 42
    • 0036007737 scopus 로고    scopus 로고
    • Isolation and characterization of Clostridium botulinum Type 'E' from soil of Gwalior, India
    • Dhaked RK, Sharma SK, Parida MM, Singh L. Isolation and characterization of Clostridium botulinum Type 'E' from soil of Gwalior, India. J Nat Toxins 2002; 11: 49-56.
    • (2002) J Nat Toxins , vol.11 , pp. 49-56
    • Dhaked, R.K.1    Sharma, S.K.2    Parida, M.M.3    Singh, L.4
  • 43
    • 0033772020 scopus 로고    scopus 로고
    • Distribution and ecology of Clostridium botulinum in fish and aquatic environments of a tropical region
    • Lalitha KV, Gopakumar K. Distribution and ecology of Clostridium botulinum in fish and aquatic environments of a tropical region. Food Microbiol 2000; 17: 535-41.
    • (2000) Food Microbiol , vol.17 , pp. 535-541
    • Lalitha, K.V.1    Gopakumar, K.2
  • 44
    • 0037196193 scopus 로고    scopus 로고
    • Occurrence of Clostridium botulinum in fresh and cured fish in retail trade in Cochin (India)
    • Lalitha KV, Surendran PK. Occurrence of Clostridium botulinum in fresh and cured fish in retail trade in Cochin (India). Int J Food Microbiol 2002; 72: 169-74.
    • (2002) Int J Food Microbiol , vol.72 , pp. 169-174
    • Lalitha, K.V.1    Surendran, P.K.2
  • 45
    • 55849125054 scopus 로고    scopus 로고
    • Multiplex PCR for the detection of Clostridium. botulinum & C. perfringens toxin genes
    • Joshy L, Chaudhry R, Chandel DS. Multiplex PCR for the detection of Clostridium. botulinum & C. perfringens toxin genes. Indian J Med Res 2008; 128: 206-8.
    • (2008) Indian J Med Res , vol.128 , pp. 206-208
    • Joshy, L.1    Chaudhry, R.2    Chandel, D.S.3
  • 46
    • 0012402970 scopus 로고
    • Contributions to the knowledge of the toxin and antitoxin of Bacilius botulinus
    • Leuchs J. Contributions to the knowledge of the toxin and antitoxin of Bacilius botulinus. Ztschr Hyg Infektskh 1910; 65: 55-84.
    • (1910) Ztschr Hyg Infektskh , vol.65 , pp. 55-84
    • Leuchs, J.1
  • 47
    • 0000451884 scopus 로고
    • Notes on Bacillus botulinus
    • Burke GS, Notes on Bacillus botulinus. J Bacteriol 1919; 4: 555-65.
    • (1919) J Bacteriol , vol.4 , pp. 555-565
    • Burke, G.S.1
  • 48
    • 0009648833 scopus 로고
    • Bulbar paralysis in cattle due to the action of toxicogenic bacillus, with a discussion on the relationship of the condition to forage poisoning (botulism)
    • Seddon HR. Bulbar paralysis in cattle due to the action of toxicogenic bacillus, with a discussion on the relationship of the condition to forage poisoning (botulism). J Comp Pathol Therap 1922; 35: 147-90.
    • (1922) J Comp Pathol Therap , vol.35 , pp. 147-190
    • Seddon, H.R.1
  • 51
    • 0345690350 scopus 로고
    • Preliminary report on the isolation of an apparently new type of Clostridium botulinum
    • Moller V, Scheibel I. Preliminary report on the isolation of an apparently new type of Clostridium botulinum. Acta Pathol Microbiol Scand 1960; 48: 80.
    • (1960) Acta Pathol Microbiol Scand , vol.48 , pp. 80
    • Moller, V.1    Scheibel, I.2
  • 53
    • 0014878949 scopus 로고
    • The genetic relatedness of proteolytic Clostridium botulinum strains
    • Lee WH, Reimann H. The genetic relatedness of proteolytic Clostridium botulinum strains. J Gen Microbiol 1970; 64: 85-90.
    • (1970) J Gen Microbiol , vol.64 , pp. 85-90
    • Lee, W.H.1    Reimann, H.2
  • 54
    • 0009618604 scopus 로고
    • Variations among strains of Clostridium botulinum and related clostridia
    • In: Herzberg M, editor. Washingtan: US Government Printing Office
    • Holdeman LV, Brooks JB. Variations among strains of Clostridium botulinum and related clostridia. In: Herzberg M, editor. Proceedings of the First US-Japan conference on toxigenic microorganisms. Washingtan: US Government Printing Office; 1970. p. 278-86.
    • (1970) Proceedings of the First US-Japan conference on toxigenic microorganisms , pp. 278-286
    • Holdeman, L.V.1    Brooks, J.B.2
  • 55
    • 0027884842 scopus 로고
    • Genetic interrelationships of proteolytic Clostridium botulinum types A, B, and F and other members of Clostridium botulinum complex as revealed by small-subunit rRNA gene sequences
    • Hutson RA, Thompson DE, Lawson PA, Schocken-Itturino RP, Bottger EC, Collins MD. Genetic interrelationships of proteolytic Clostridium botulinum types A, B, and F and other members of Clostridium botulinum complex as revealed by small-subunit rRNA gene sequences. Antonie van Leeuwenhoek 1993; 64: 273-83.
    • (1993) Antonie van Leeuwenhoek , vol.64 , pp. 273-283
    • Hutson, R.A.1    Thompson, D.E.2    Lawson, P.A.3    Schocken-Itturino, R.P.4    Bottger, E.C.5    Collins, M.D.6
  • 56
    • 0027339489 scopus 로고
    • Genetic interrelationships of saccharolytic Clostridium botulinum types B, E and F and related clostridia as revealed by small-subunit rRNA gene sequences
    • Hutson RA, Thompson DE, Collins MD. Genetic interrelationships of saccharolytic Clostridium botulinum types B, E and F and related clostridia as revealed by small-subunit rRNA gene sequences. FEMS Microbiol Lett 1993; 108: 103-10.
    • (1993) FEMS Microbiol Lett , vol.108 , pp. 103-110
    • Hutson, R.A.1    Thompson, D.E.2    Collins, M.D.3
  • 58
    • 0000760971 scopus 로고
    • Genus III. Clostridium prazmowski 1980, 23
    • In: Buchanen RE, Gibson NE, editors. 8th ed, Baltimore: Williams & Wilkins
    • Smith LDS, Hobbs G. Genus III. Clostridium prazmowski 1980, 23. In: Buchanen RE, Gibson NE, editors. Bergey's mannual of determinative bacteriology, 8th ed. Baltimore: Williams & Wilkins; 1974. p. 551-72.
    • (1974) Bergey's mannual of determinative bacteriology , pp. 551-572
    • Smith, L.D.S.1    Hobbs, G.2
  • 59
    • 0023678966 scopus 로고
    • Clostridium botulinum sp. nov: A genetically homogenous group composed of all strains of Clostridium botulinum toxin type G and some non-toxigenic strains previously identified as Clostridium subterminale or Clostridium hastiforme
    • Suen JG, Hatheway CL, Steigerwalt AG, Brenner DJ. Clostridium botulinum sp. nov: A genetically homogenous group composed of all strains of Clostridium botulinum toxin type G and some non-toxigenic strains previously identified as Clostridium subterminale or Clostridium hastiforme. Int J Syst Bacteriol 1988; 38: 375-81.
    • (1988) Int J Syst Bacteriol , vol.38 , pp. 375-381
    • Suen, J.G.1    Hatheway, C.L.2    Steigerwalt, A.G.3    Brenner, D.J.4
  • 61
    • 0021990059 scopus 로고
    • Isolation of an organism resembling Clostridium beratii which produce type F botulinal toxin from an infant with botulism
    • Hall JD, McCroskey LM, Pinkomb BJ, Hatheway CL. Isolation of an organism resembling Clostridium beratii which produce type F botulinal toxin from an infant with botulism. J Clin Microbiol 1985; 21: 654-5.
    • (1985) J Clin Microbiol , vol.21 , pp. 654-655
    • Hall, J.D.1    McCroskey, L.M.2    Pinkomb, B.J.3    Hatheway, C.L.4
  • 62
    • 0029080131 scopus 로고
    • Molecular genetics clostridial neurotoxins
    • Minton NP. Molecular genetics clostridial neurotoxins. Curr Top Microbiol Immunol 1995; 95: 161-95.
    • (1995) Curr Top Microbiol Immunol , vol.95 , pp. 161-195
    • Minton, N.P.1
  • 65
    • 34347395377 scopus 로고    scopus 로고
    • Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes
    • Sebaihia M, Peck MW, Minton NP, Thomson NR, Holden MTG, Mitchell WJ, et al. Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes. Genome Res 2007; 17: 1082-92.
    • (2007) Genome Res , vol.17 , pp. 1082-1092
    • Sebaihia, M.1    Peck, M.W.2    Minton, N.P.3    Thomson, N.R.4    Holden, M.T.G.5    Mitchell, W.J.6
  • 66
    • 43049146299 scopus 로고    scopus 로고
    • Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids
    • Smith TJ, Hill KK, Foley BT, Detter JC, Munk AC, Bruce DC, et al. Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids. PLoS ONE. 2007; 2: E1271-E1271.
    • (2007) PLoS ONE. , vol.2
    • Smith, T.J.1    Hill, K.K.2    Foley, B.T.3    Detter, J.C.4    Munk, A.C.5    Bruce, D.C.6
  • 69
    • 33747148816 scopus 로고    scopus 로고
    • Clostridium botulinum and the safety of minimally heated, chilled foods: An emerging issue?
    • Peck MW. Clostridium botulinum and the safety of minimally heated, chilled foods: an emerging issue? J Appl Micrbiol 2006; 101: 556-70.
    • (2006) J Appl Micrbiol , vol.101 , pp. 556-570
    • Peck, M.W.1
  • 70
    • 0029080327 scopus 로고
    • Intracellular target and metalloprotease activity of tetanus and botulinum neurotoxins
    • Schiavo G, Rossetto O, Tonello F, Montecucco C. Intracellular target and metalloprotease activity of tetanus and botulinum neurotoxins. Curr Top Microbiol Immunol 1995; 195: 257-74.
    • (1995) Curr Top Microbiol Immunol , vol.195 , pp. 257-274
    • Schiavo, G.1    Rossetto, O.2    Tonello, F.3    Montecucco, C.4
  • 71
    • 33744542067 scopus 로고    scopus 로고
    • Botulism: The many faces of botulinum toxin and its potential for bioterrorism
    • Villar RG, Elliot SP, Davenport KM. Botulism: the many faces of botulinum toxin and its potential for bioterrorism. Infect Dis Clin N Am 2006; 20: 313-27.
    • (2006) Infect Dis Clin N Am , vol.20 , pp. 313-327
    • Villar, R.G.1    Elliot, S.P.2    Davenport, K.M.3
  • 72
    • 0016678458 scopus 로고
    • Molecular construction of Clostridium botulinum type A toxins
    • Sugii S, Sakaguchi G. Molecular construction of Clostridium botulinum type A toxins. Infect Immun 1975; 12: 1262-70.
    • (1975) Infect Immun , vol.12 , pp. 1262-1270
    • Sugii, S.1    Sakaguchi, G.2
  • 74
    • 0031866118 scopus 로고    scopus 로고
    • Biophysical characterization of the stability of the 150-Kilodalton botulinum toxin, the non-toxic component and the 900-Kilodalton botulinum toxin complex species
    • Chen F, Kuziemco GM, Stevens R. Biophysical characterization of the stability of the 150-Kilodalton botulinum toxin, the non-toxic component and the 900-Kilodalton botulinum toxin complex species. Infect Immun 1998; 66: 2420-5.
    • (1998) Infect Immun , vol.66 , pp. 2420-2425
    • Chen, F.1    Kuziemco, G.M.2    Stevens, R.3
  • 75
    • 0000186928 scopus 로고
    • Structure and function of botulinum toxins
    • In: Alouf JE, Fehrenbach FJ, Freer JH, Jeljaszewics J, editors. London: Academic Press
    • Sakaguchi G, Kozaki S, Ohnishi I. Structure and function of botulinum toxins. In: Alouf JE, Fehrenbach FJ, Freer JH, Jeljaszewics J, editors. Bacterial protein toxins. London: Academic Press; 1984. p. 435-43.
    • (1984) Bacterial protein toxins , pp. 435-443
    • Sakaguchi, G.1    Kozaki, S.2    Ohnishi, I.3
  • 76
    • 0028310404 scopus 로고
    • Mechanism of action of tetanus and botulinum neurotoxins
    • Montecucco C, Schiavo G. Mechanism of action of tetanus and botulinum neurotoxins. Mol Microbiol 1994; 13: 1-8.
    • (1994) Mol Microbiol , vol.13 , pp. 1-8
    • Montecucco, C.1    Schiavo, G.2
  • 77
    • 0027997409 scopus 로고
    • Botulinum G neurotoxin cleaves VAMP/synaptobrevin at a single Ala-Ala peptide bond
    • Schiavo G, Malizio C, Trimble WS, Polverino de Laureto P, Milan G, et al. Botulinum G neurotoxin cleaves VAMP/synaptobrevin at a single Ala-Ala peptide bond. J Biol Chem 1994; 269: 20213-6.
    • (1994) J Biol Chem , vol.269 , pp. 20213-20216
    • Schiavo, G.1    Malizio, C.2    Trimble, W.S.3    de Polverino Laureto, P.4    Milan, G.5
  • 79
    • 0027366557 scopus 로고
    • Identification of the nerve terminal targets of botulinum neurotoxin serotypes A, D, and E
    • Schiavo G, Rossetto O, Catsicas S, Polverino de Laureto P, DasGupta BR, et al. Identification of the nerve terminal targets of botulinum neurotoxin serotypes A, D, and E. J Biol Chem 1993; 268: 23784-7.
    • (1993) J Biol Chem , vol.268 , pp. 23784-23787
    • Schiavo, G.1    Rossetto, O.2    Catsicas, S.3    de Polverino Laureto, P.4    Dasgupta, B.R.5
  • 80
    • 0027438184 scopus 로고
    • Botulinum neurotoxin serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds
    • Schiavo G, Santucci A, DasGupta BR, Mehta PP, Jontes J, Benfenati F, et al. Botulinum neurotoxin serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds. FEBS Lett 1993; 335: 99-103.
    • (1993) FEBS Lett , vol.335 , pp. 99-103
    • Schiavo, G.1    Santucci, A.2    Dasgupta, B.R.3    Mehta, P.P.4    Jontes, J.5    Benfenati, F.6
  • 82
    • 0026497466 scopus 로고
    • Tetanus and botulism B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin
    • Schiavo G, Benfenati F, Poulain B, Rossetto O, Polverino de Laureto P, DasGupta BR, et al. Tetanus and botulism B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature 1992; 359: 832-5.
    • (1992) Nature , vol.359 , pp. 832-835
    • Schiavo, G.1    Benfenati, F.2    Poulain, B.3    Rossetto, O.4    de Polverino Laureto, P.5    Dasgupta, B.R.6
  • 83
    • 0027241009 scopus 로고
    • Botulinum neurotoxin serotype F is a zinc endopeptidase specific for VAMP/synaptobrevin
    • Schiavo G, Shone CC, Rossetto O, Alexander FC, Montecucco C. Botulinum neurotoxin serotype F is a zinc endopeptidase specific for VAMP/synaptobrevin. J Biol Chem 1993; 268: 11516-9.
    • (1993) J Biol Chem , vol.268 , pp. 11516-11519
    • Schiavo, G.1    Shone, C.C.2    Rossetto, O.3    Alexander, F.C.4    Montecucco, C.5
  • 84
    • 0028199063 scopus 로고
    • Cleavage of members of synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin
    • Yamazaki S, Baumeister A, Binz T, Blasi J, Link E, Cornille F, et al. Cleavage of members of synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin. J Biol Chem 1994; 269: 12764-72.
    • (1994) J Biol Chem , vol.269 , pp. 12764-12772
    • Yamazaki, S.1    Baumeister, A.2    Binz, T.3    Blasi, J.4    Link, E.5    Cornille, F.6
  • 85
    • 0027432376 scopus 로고
    • Botulinum neurotoxin C1 block the release by means of cleavage HPC-1/syntaxin
    • Blasi J, Chapman ER, Yamasaki S, Binz T, Niemann H, Jahn R. Botulinum neurotoxin C1 block the release by means of cleavage HPC-1/syntaxin. EMBO J 1993; 12: 4821-8.
    • (1993) EMBO J , vol.12 , pp. 4821-4828
    • Blasi, J.1    Chapman, E.R.2    Yamasaki, S.3    Binz, T.4    Niemann, H.5    Jahn, R.6
  • 86
    • 0028922592 scopus 로고
    • Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins
    • Schiavo G, Shone CC, Bennett MK, Scheller RH, Montecucco C. Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins. J Biol Chem 1995; 270: 10566-70.
    • (1995) J Biol Chem , vol.270 , pp. 10566-10570
    • Schiavo, G.1    Shone, C.C.2    Bennett, M.K.3    Scheller, R.H.4    Montecucco, C.5
  • 90
    • 0016909121 scopus 로고
    • Clostridium botulinum and its importance in fishery products
    • In: Chechester CO, Mrak EM Stewart GF, editors, New York: Academic Press Inc
    • Hobbs G. Clostridium botulinum and its importance in fishery products. In: Chechester CO, Mrak EM Stewart GF, editors. Advances in food research. New York: Academic Press Inc. 1976. p. 135-85.
    • (1976) Advances in food research , pp. 135-185
    • Hobbs, G.1
  • 92
    • 0000860810 scopus 로고    scopus 로고
    • Genus Clostridium
    • In: Sneath PHA, Mair NS, Sharpe ME, Hold JG, editors, Baltimore, MA: Williams and Wilkins
    • Cato EP, George WL, Finegold SM. Genus Clostridium. In: Sneath PHA, Mair NS, Sharpe ME, Hold JG, editors. Bergey's 1986. manual of systematic bacteriology, vol. 2, Baltimore, MA: Williams and Wilkins; p. 1141-200.
    • Bergey's 1986. manual of systematic bacteriology , vol.2 , pp. 1141-1200
    • Cato, E.P.1    George, W.L.2    Finegold, S.M.3
  • 93
    • 84985222566 scopus 로고
    • Effect of oxidation-reduction potential on the outgrowth and chemical inhibition of Clostridium botulinum 10755A spores
    • Smoot LA, Pierson MD. Effect of oxidation-reduction potential on the outgrowth and chemical inhibition of Clostridium botulinum 10755A spores. J Food Sci 1979; 44: 700-4.
    • (1979) J Food Sci , vol.44 , pp. 700-704
    • Smoot, L.A.1    Pierson, M.D.2
  • 94
    • 0000236389 scopus 로고
    • Toxin production by Clostridium botulinum type E in smoked fish in relation to the measured oxidation reduction potential (Eh), packaging method, and associated microflora
    • Huss HH, Schaeffer I, Pedersen A, Jepsen A. Toxin production by Clostridium botulinum type E in smoked fish in relation to the measured oxidation reduction potential (Eh), packaging method, and associated microflora. Adv Fish Sci Technol 1980; 13: 476-9.
    • (1980) Adv Fish Sci Technol , vol.13 , pp. 476-479
    • Huss, H.H.1    Schaeffer, I.2    Pedersen, A.3    Jepsen, A.4
  • 97
    • 0011894564 scopus 로고
    • Low temperature growth of type E Clostridium botulinum spores. 2. Effects of solutes and incubation temperature
    • Emodi AS, Lechowich RV. Low temperature growth of type E Clostridium botulinum spores. 2. Effects of solutes and incubation temperature. J Food Sci 1969; 34: 82-93.
    • (1969) J Food Sci , vol.34 , pp. 82-93
    • Emodi, A.S.1    Lechowich, R.V.2
  • 98
    • 0036570711 scopus 로고    scopus 로고
    • Rapid and sensitive detection of biological warfare agents using time-resolved fluorescence assays
    • Peruski AH, Johnson LH, Peruski LF. Rapid and sensitive detection of biological warfare agents using time-resolved fluorescence assays. J Immunol Meth 2002; 263: 35-41.
    • (2002) J Immunol Meth , vol.263 , pp. 35-41
    • Peruski, A.H.1    Johnson, L.H.2    Peruski, L.F.3
  • 99
    • 6944237312 scopus 로고    scopus 로고
    • Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells
    • Dong M, Tepp WH, Johnson EA, Chapman ER. Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells. Proc Natl Acad Sci USA 2004; 101: 14701-6.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14701-14706
    • Dong, M.1    Tepp, W.H.2    Johnson, E.A.3    Chapman, E.R.4
  • 100
    • 33144489209 scopus 로고    scopus 로고
    • Detection of type A, B, E, and F Clostridium botulinum neurotoxins in foods by using an amplified enzyme-linked immunosorbent assay with digoxigenin-labeled antibodies
    • Sharma SK, Ferreira JL, Eblen BS, Whiting RC. Detection of type A, B, E, and F Clostridium botulinum neurotoxins in foods by using an amplified enzyme-linked immunosorbent assay with digoxigenin-labeled antibodies. Appl Environ Microbiol 2006; 72: 1231-8.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 1231-1238
    • Sharma, S.K.1    Ferreira, J.L.2    Eblen, B.S.3    Whiting, R.C.4
  • 103
    • 44349120485 scopus 로고    scopus 로고
    • Attomolar detection of botulinum toxin type A in complex biological matrices
    • Bagramyan K, Barash JR, Arnon SS, Kalkum M. Attomolar detection of botulinum toxin type A in complex biological matrices. PLoS ONE 2008; 3(4): e2041.
    • (2008) PLoS ONE , vol.3 , Issue.4
    • Bagramyan, K.1    Barash, J.R.2    Arnon, S.S.3    Kalkum, M.4
  • 104
    • 1242314782 scopus 로고    scopus 로고
    • A highly sensitive immuno-polymerase chain reaction assay for Clostridium botulinum neurotoxin type A
    • Chao HY, Wang YC, Tang SS, Liu HW. A highly sensitive immuno-polymerase chain reaction assay for Clostridium botulinum neurotoxin type A. Toxicon 2004; 43: 27-34.
    • (2004) Toxicon , vol.43 , pp. 27-34
    • Chao, H.Y.1    Wang, Y.C.2    Tang, S.S.3    Liu, H.W.4
  • 105
    • 33646584524 scopus 로고    scopus 로고
    • A liposome-PCR assay for the ultrasensitive detection of biological toxins
    • Mason JT, Xu L, Sheng ZM, O'Leary TJ. A liposome-PCR assay for the ultrasensitive detection of biological toxins. Nat Biotechnol 2006; 24: 555-7.
    • (2006) Nat Biotechnol , vol.24 , pp. 555-557
    • Mason, J.T.1    Xu, L.2    Sheng, Z.M.3    O'Leary, T.J.4
  • 106
    • 33745006171 scopus 로고    scopus 로고
    • Enzyme-amplified protein microarray and a fluidic renewable surface fluorescence immunoassay for botulinum neurotoxin detection using high affinity recombinant antibodies
    • Varnum SM, Warner MG, Dockendorff B, Anheier Jr. NC, Lou J, Marks JD, et al. Enzyme-amplified protein microarray and a fluidic renewable surface fluorescence immunoassay for botulinum neurotoxin detection using high affinity recombinant antibodies. Analytica Chimica Acta 2006; 570: 137-43.
    • (2006) Analytica Chimica Acta , vol.570 , pp. 137-143
    • Varnum, S.M.1    Warner, M.G.2    Dockendorff, B.3    Anheier Jr., N.C.4    Lou, J.5    Marks, J.D.6
  • 108
    • 2942511921 scopus 로고    scopus 로고
    • Ganglioside-liposome immunoassay for the detection of botulinum toxin
    • Ahn-Yoon S, DeCory TR, Durst RA. Ganglioside-liposome immunoassay for the detection of botulinum toxin. Anal Bioanal Chem 2004; 378: 68-75.
    • (2004) Anal Bioanal Chem , vol.378 , pp. 68-75
    • Ahn-Yoon, S.1    de Cory, T.R.2    Durst, R.A.3
  • 109
    • 0031609683 scopus 로고    scopus 로고
    • Botulinum neurotoxins: Mode of action and detection
    • Wictome M, Shone CC. Botulinum neurotoxins: Mode of action and detection. J Appl Microbiol 1998; 84: S87-97.
    • (1998) J Appl Microbiol , vol.84
    • Wictome, M.1    Shone, C.C.2
  • 110
    • 0031839302 scopus 로고    scopus 로고
    • Clinical spectrum of botulism
    • Cherington M. Clinical spectrum of botulism. Muscle Nerve 1998; 21: 701-10.
    • (1998) Muscle Nerve , vol.21 , pp. 701-710
    • Cherington, M.1
  • 111
    • 0021072879 scopus 로고
    • Fluorescent-antibody reagents for the identification of Clostridium botulinum
    • Glasby C, Hatheway CL. Fluorescent-antibody reagents for the identification of Clostridium botulinum. J Clin Microbiol 1983; 18: 1378-83.
    • (1983) J Clin Microbiol , vol.18 , pp. 1378-1383
    • Glasby, C.1    Hatheway, C.L.2
  • 112
    • 78649454214 scopus 로고
    • Immunodiffusion detection of Clostridium botulinum colonies
    • Lilly T, Kautter DA, Lynt RK, Solomon HM. Immunodiffusion detection of Clostridium botulinum colonies. J Food Prot 1984; 47: 868-75.
    • (1984) J Food Prot , vol.47 , pp. 868-875
    • Lilly, T.1    Kautter, D.A.2    Lynt, R.K.3    Solomon, H.M.4
  • 114
    • 0028935520 scopus 로고
    • Immunological detection of Clostridium botulinum type A in therapeutic preparations
    • Ekong TAN, McLellan K, Sesardic D. Immunological detection of Clostridium botulinum type A in therapeutic preparations. J Immunol Meth 1995; 180: 181-91.
    • (1995) J Immunol Meth , vol.180 , pp. 181-191
    • Ekong, T.A.N.1    McLellan, K.2    Sesardic, D.3
  • 115
    • 0028123835 scopus 로고
    • Enzyme-linked immunosorbent assay and enzyme-linked coagulation assay for detection of Clostridium botulinum neurotoxins A, B, and E and solution-phase complexes with dual-label antibodies
    • Doellgast GJ, Beard GA, Bottoms JD, Cheng T, Roh BH, Roman MG, et al. Enzyme-linked immunosorbent assay and enzyme-linked coagulation assay for detection of Clostridium botulinum neurotoxins A, B, and E and solution-phase complexes with dual-label antibodies. J Clin Microbiol 1994; 32: 105-11.
    • (1994) J Clin Microbiol , vol.32 , pp. 105-111
    • Doellgast, G.J.1    Beard, G.A.2    Bottoms, J.D.3    Cheng, T.4    Roh, B.H.5    Roman, M.G.6
  • 116
    • 0036956762 scopus 로고    scopus 로고
    • Detection by PCR-enzyme-linked immunosorbent assay of Clostridium botulinum in fish and environmental samples from a coastal area in northern France
    • Fach P, Perrelle S, Dilasser F, Grout J, Dargaignaratz C, Botella L, et al. Detection by PCR-enzyme-linked immunosorbent assay of Clostridium botulinum in fish and environmental samples from a coastal area in northern France. Appl Environ Microbiol 2002; 68: 5870-6.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 5870-5876
    • Fach, P.1    Perrelle, S.2    Dilasser, F.3    Grout, J.4    Dargaignaratz, C.5    Botella, L.6
  • 117
    • 0029893774 scopus 로고    scopus 로고
    • Development of novel assays for botulinum type A and B neurotoxins based on their endopeptidase activities
    • Hallis B, James BAF, Shone CC. Development of novel assays for botulinum type A and B neurotoxins based on their endopeptidase activities. J Clin Microbiol 1996; 34: 1934-8.
    • (1996) J Clin Microbiol , vol.34 , pp. 1934-1938
    • Hallis, B.1    James, B.A.F.2    Shone, C.C.3
  • 118
    • 0037228895 scopus 로고    scopus 로고
    • Fluorigenic substrates for the protease activities of botulinum neurotoxins, serotypes A, B, and F
    • Schmidt JJ, Stafford RG. Fluorigenic substrates for the protease activities of botulinum neurotoxins, serotypes A, B, and F. Appl Environ Microbiol 2003; 69: 297-303.
    • (2003) Appl Environ Microbiol , vol.69 , pp. 297-303
    • Schmidt, J.J.1    Stafford, R.G.2
  • 119
    • 84986791308 scopus 로고
    • An improved assay for identification of type A Clostridium botulinum using the polymerase chain reaction
    • Ferreira JL, Handy MK, McCay SG, Baumstark BR. An improved assay for identification of type A Clostridium botulinum using the polymerase chain reaction. J Rapid Methods Automat Microbiol 1992; 1: 293-9.
    • (1992) J Rapid Methods Automat Microbiol , vol.1 , pp. 293-299
    • Ferreira, J.L.1    Handy, M.K.2    McCay, S.G.3    Baumstark, B.R.4
  • 120
    • 0027163418 scopus 로고
    • Gene probes for identification of the botulinum neurotoxin gene and specific identification of neurotoxin types B, E and F
    • Campbell KD, Collins MD, East AK. Gene probes for identification of the botulinum neurotoxin gene and specific identification of neurotoxin types B, E and F. J Clin Microbiol 1993; 31: 2255-62.
    • (1993) J Clin Microbiol , vol.31 , pp. 2255-2262
    • Campbell, K.D.1    Collins, M.D.2    East, A.K.3
  • 121
    • 0027165316 scopus 로고
    • Detection of genes encoding botulinum neurotoxins types A to E by polymerase chain reaction
    • Szabo EA, Pemberton JM, Desmarchelier PM. Detection of genes encoding botulinum neurotoxins types A to E by polymerase chain reaction. Appl Environ Microbiol 1993; 59: 3011-20.
    • (1993) Appl Environ Microbiol , vol.59 , pp. 3011-3020
    • Szabo, E.A.1    Pemberton, J.M.2    Desmarchelier, P.M.3
  • 122
    • 0027956379 scopus 로고
    • Polymerase chain reaction for detection of Clostridium botulinum type A, B, and E in Food, soil, and infant feces
    • Szabo EA, Pemberton JM, Gibson AM, Eyles MJ, Desmarchelier PM. Polymerase chain reaction for detection of Clostridium botulinum type A, B, and E in Food, soil, and infant feces. J Appl Bacteriol 1994; 76: 539-45.
    • (1994) J Appl Bacteriol , vol.76 , pp. 539-545
    • Szabo, E.A.1    Pemberton, J.M.2    Gibson, A.M.3    Eyles, M.J.4    Desmarchelier, P.M.5
  • 123
    • 0027328552 scopus 로고
    • Polymerase chain reaction for the rapid identification of Clostridium botulinum type A strains and detection in food samples
    • Fach P, Hauser D, Guillou JP, Popoff MR. Polymerase chain reaction for the rapid identification of Clostridium botulinum type A strains and detection in food samples. J Appl Bacteriol 1993; 75: 234-9.
    • (1993) J Appl Bacteriol , vol.75 , pp. 234-239
    • Fach, P.1    Hauser, D.2    Guillou, J.P.3    Popoff, M.R.4
  • 124
    • 0030201354 scopus 로고    scopus 로고
    • Detection of Clostridium botulinum in fish and environmental samples using polymerase chain reaction
    • Hielm S, Hyytia E, Ridell J, Korkeala H. Detection of Clostridium botulinum in fish and environmental samples using polymerase chain reaction. Int J Food Microbiol 1996; 31: 357-65.
    • (1996) Int J Food Microbiol , vol.31 , pp. 357-365
    • Hielm, S.1    Hyytia, E.2    Ridell, J.3    Korkeala, H.4
  • 125
    • 0030850616 scopus 로고    scopus 로고
    • Detection of Clostridium botulinum types A, B, E and F in foods by PCR and DNA probe
    • Aranda E, Rodriguez MM, Asensio MA, Cordoba JJ. Detection of Clostridium botulinum types A, B, E and F in foods by PCR and DNA probe. Lett Appl Microbiol 1997; 25: 186-90.
    • (1997) Lett Appl Microbiol , vol.25 , pp. 186-190
    • Aranda, E.1    Rodriguez, M.M.2    Asensio, M.A.3    Cordoba, J.J.4
  • 126
    • 0035656171 scopus 로고    scopus 로고
    • Multiplex PCR assay for detection and identification of Clostridium botulinum type A, B, E, and F in food and fecal material
    • Lindstrom M, Keto R, Markkula A, Nevas M, Hielm S, Korkeala H. Multiplex PCR assay for detection and identification of Clostridium botulinum type A, B, E, and F in food and fecal material. Appl Environ Microbiol 2001; 67: 5694-9.
    • (2001) Appl Environ Microbiol , vol.67 , pp. 5694-5699
    • Lindstrom, M.1    Keto, R.2    Markkula, A.3    Nevas, M.4    Hielm, S.5    Korkeala, H.6
  • 127
    • 0028792467 scopus 로고
    • Genome analysis of Clostridium botulinum type A by pulsed-field gel electrophoresis
    • Lin WJ, Johnson EA. Genome analysis of Clostridium botulinum type A by pulsed-field gel electrophoresis. Appl Environ Microbiol 1995; 61: 4441-7.
    • (1995) Appl Environ Microbiol , vol.61 , pp. 4441-4447
    • Lin, W.J.1    Johnson, E.A.2
  • 128
    • 0344447097 scopus 로고    scopus 로고
    • Genomic analysis of Clostridium botulinum group II by pulsed-field gel electrophoresis
    • Hielm S, Bjorkroth J, Hyytia E, Korkeala H. Genomic analysis of Clostridium botulinum group II by pulsed-field gel electrophoresis. Appl Environ Microbiol 1998; 64: 703-8.
    • (1998) Appl Environ Microbiol , vol.64 , pp. 703-708
    • Hielm, S.1    Bjorkroth, J.2    Hyytia, E.3    Korkeala, H.4
  • 129
    • 0345004971 scopus 로고    scopus 로고
    • Ribotyping as an identification tool for Clostridium botulinum species causing human botulism
    • Hielm S, Bjorkroth J, Hyytia, E, Korkeala H. Ribotyping as an identification tool for Clostridium botulinum species causing human botulism. Int J Food Microbiol 1999; 47: 121-31.
    • (1999) Int J Food Microbiol , vol.47 , pp. 121-131
    • Hielm, S.1    Bjorkroth, J.2    Hyytia, E.3    Korkeala, H.4
  • 131
    • 0023798433 scopus 로고
    • Human response to botulinum pentavalent (ABCDE) toxoid determined by a neutralization test and by an enzyme linked immunosorbent assay
    • Siegel LS. Human response to botulinum pentavalent (ABCDE) toxoid determined by a neutralization test and by an enzyme linked immunosorbent assay. J Clin Microbiol 1988; 25: 2351-6.
    • (1988) J Clin Microbiol , vol.25 , pp. 2351-2356
    • Siegel, L.S.1
  • 132
    • 0037093615 scopus 로고    scopus 로고
    • Friedlander AM, et al. Antibody response to a delayed booster dose of anthrax vaccine and botulinum toxoid
    • Pittman PR, Hack D, Mangiafico J, Gibbs P, McKee KT Jr., Friedlander AM, et al. Antibody response to a delayed booster dose of anthrax vaccine and botulinum toxoid. Vaccine 2002; 20: 2107-15.
    • (2002) Vaccine , vol.20 , pp. 2107-2115
    • Pittman, P.R.1    Hack, D.2    Mangiafico, J.3    Gibbs, P.4    McKee Jr., K.T.5
  • 133
    • 0033748727 scopus 로고    scopus 로고
    • Development of vaccine for prevention of botulism
    • Byrne MP, Smith LA. Development of vaccine for prevention of botulism. Biochimie 2000; 82: 955-66.
    • (2000) Biochimie , vol.82 , pp. 955-966
    • Byrne, M.P.1    Smith, L.A.2
  • 134
    • 0033023671 scopus 로고    scopus 로고
    • Structure, activity and immune (T & B cell) recognition of botulinum neurotoxin
    • Atassi MZ, Oshima M. Structure, activity and immune (T & B cell) recognition of botulinum neurotoxin. Crit Rev Immunol 1999; 19: 219-60.
    • (1999) Crit Rev Immunol , vol.19 , pp. 219-260
    • Atassi, M.Z.1    Oshima, M.2
  • 135
    • 0034876256 scopus 로고    scopus 로고
    • Candidate vaccine against botulinum neurotoxin serotype A derived from a Venezuelan equine encephalitis virus vector system
    • Lee JS, Pushko P, Parker MD, Dertzbaugh MT, Smith LA, Smith JF. Candidate vaccine against botulinum neurotoxin serotype A derived from a Venezuelan equine encephalitis virus vector system. Infect Immun 2001; 69: 5709-15.
    • (2001) Infect Immun , vol.69 , pp. 5709-5715
    • Lee, J.S.1    Pushko, P.2    Parker, M.D.3    Dertzbaugh, M.T.4    Smith, L.A.5    Smith, J.F.6
  • 136
    • 0031658344 scopus 로고    scopus 로고
    • Purification, potency and efficacy of botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate
    • Byrne MP, Smith TJ, Montegomery VA, Smith LA. Purification, potency and efficacy of botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate. Infect Immun 1998; 66: 4817-22.
    • (1998) Infect Immun , vol.66 , pp. 4817-4822
    • Byrne, M.P.1    Smith, T.J.2    Montegomery, V.A.3    Smith, L.A.4
  • 137
    • 0038544028 scopus 로고    scopus 로고
    • DNA vaccination protects against botulinum neurotoxin type F
    • Bennett AM, Perkins SD, Holley JL. DNA vaccination protects against botulinum neurotoxin type F. Vaccine 2003; 21: 3110-7.
    • (2003) Vaccine , vol.21 , pp. 3110-3117
    • Bennett, A.M.1    Perkins, S.D.2    Holley, J.L.3
  • 138
    • 34848907990 scopus 로고    scopus 로고
    • Protective immunity against botulism provided by a single dose vaccination with an adenovirus-vectored vaccine
    • Zeng M, Xu Q, Elias M, Pichichero ME, Simpson LL, Smith LA. Protective immunity against botulism provided by a single dose vaccination with an adenovirus-vectored vaccine. Vaccine 2007; 25: 7540-8.
    • (2007) Vaccine , vol.25 , pp. 7540-7548
    • Zeng, M.1    Xu, Q.2    Elias, M.3    Pichichero, M.E.4    Simpson, L.L.5    Smith, L.A.6
  • 139
    • 62549084249 scopus 로고    scopus 로고
    • An adenoviral vector-based mucosal vaccine is effective in protection against botulism
    • Xu Q, Pichichero ME, Simpson LL, Elias M, Smith LA, Zeng M. An adenoviral vector-based mucosal vaccine is effective in protection against botulism. Gene Ther 2009; 16: 367-75.
    • (2009) Gene Ther , vol.16 , pp. 367-375
    • Xu, Q.1    Pichichero, M.E.2    Simpson, L.L.3    Elias, M.4    Smith, L.A.5    Zeng, M.6
  • 140
    • 0021356534 scopus 로고
    • Equine antitoxin use and other factors that predict outcome in type A foodborne botulism
    • Tackett CO, Shandera WX, Mann JM, Hargrett, NT, Blake PA. Equine antitoxin use and other factors that predict outcome in type A foodborne botulism. Am J Med 1984; 76: 794-8.
    • (1984) Am J Med , vol.76 , pp. 794-798
    • Tackett, C.O.1    Shandera, W.X.2    Mann, J.M.3    Hargrett, N.T.4    Blake, P.A.5
  • 141
    • 34147178991 scopus 로고    scopus 로고
    • Clinical mimics of infant botulism
    • Francisco AM, Arnon SS. Clinical mimics of infant botulism. Pediatrics 2007; 119: 826-8.
    • (2007) Pediatrics , vol.119 , pp. 826-828
    • Francisco, A.M.1    Arnon, S.S.2
  • 142
    • 0019161371 scopus 로고
    • Clostridium botulinum neurotoxin
    • Sugiyama H. Clostridium botulinum neurotoxin. Microbiol Rev 1980; 44: 419-48.
    • (1980) Microbiol Rev , vol.44 , pp. 419-448
    • Sugiyama, H.1
  • 143
    • 0018958307 scopus 로고
    • Hypersensitivity reactions associated with botulinal antitoxin
    • Black RE, Gunn RA. Hypersensitivity reactions associated with botulinal antitoxin. Am J Med 1980; 69: 567-70.
    • (1980) Am J Med , vol.69 , pp. 567-570
    • Black, R.E.1    Gunn, R.A.2
  • 144
    • 34147140020 scopus 로고    scopus 로고
    • Creation and development of the public service orphan drug human botulism immune globulin
    • Arnon SS. Creation and development of the public service orphan drug human botulism immune globulin. Pediatrics 2007; 119: 785-9.
    • (2007) Pediatrics , vol.119 , pp. 785-789
    • Arnon, S.S.1
  • 146
    • 2942599724 scopus 로고    scopus 로고
    • Cure of experimental botulism and antibotulismic effect of toosendanin
    • Shi YL, Wang ZF. Cure of experimental botulism and antibotulismic effect of toosendanin. Acta Pharmacol Sin 2004; 25: 839-48.
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 839-848
    • Shi, Y.L.1    Wang, Z.F.2
  • 147
    • 34248208151 scopus 로고    scopus 로고
    • Biological effects of toosendanin, a triterpenoid extracted from Chinese traditional medicine
    • Shi YL, Li MF. Biological effects of toosendanin, a triterpenoid extracted from Chinese traditional medicine. Prog Neurobiol 2007; 82: 1-10.
    • (2007) Prog Neurobiol , vol.82 , pp. 1-10
    • Shi, Y.L.1    Li, M.F.2
  • 149
    • 33646453916 scopus 로고    scopus 로고
    • Identification of a potent botulinum neurotoxin a protease inhibitor using in situ lead identification chemistry
    • Boldt GE, Kennedy JP, Janda KD. Identification of a potent botulinum neurotoxin a protease inhibitor using in situ lead identification chemistry. Org Lett 2006; 8: 1729-32.
    • (2006) Org Lett , vol.8 , pp. 1729-1732
    • Boldt, G.E.1    Kennedy, J.P.2    Janda, K.D.3
  • 150
    • 33947502906 scopus 로고    scopus 로고
    • Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons
    • Burnett JC, Ruthel G, Stegmann CM, Panchal RG, Nguyen TL, Hermone AR, et al. Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons. J Biol Chem 2007; 282: 5004-14.
    • (2007) J Biol Chem , vol.282 , pp. 5004-5014
    • Burnett, J.C.1    Ruthel, G.2    Stegmann, C.M.3    Panchal, R.G.4    Nguyen, T.L.5    Hermone, A.R.6
  • 151
    • 49649121294 scopus 로고    scopus 로고
    • Structure and substrate based inhibitor design for Clostridium botulinum neurotoxin serotype A
    • Kumaran D, Rawat R, Ludivico ML, Ahmed SA, Swaminathan S. Structure and substrate based inhibitor design for Clostridium botulinum neurotoxin serotype A. J Biol Chem 2008; 283: 18883-91.
    • (2008) J Biol Chem , vol.283 , pp. 18883-18891
    • Kumaran, D.1    Rawat, R.2    Ludivico, M.L.3    Ahmed, S.A.4    Swaminathan, S.5
  • 152
    • 44349178037 scopus 로고    scopus 로고
    • Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex
    • Silvaggi NR, Wilson D, Tzipori S, Allen KN. Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex. Biochemistry 2008; 47: 5736-45.
    • (2008) Biochemistry , vol.47 , pp. 5736-5745
    • Silvaggi, N.R.1    Wilson, D.2    Tzipori, S.3    Allen, K.N.4
  • 153
    • 33947692620 scopus 로고    scopus 로고
    • Strategies to design inhibitors of Clostridium botulinum neurotoxins
    • Cai S, Singh BR. Strategies to design inhibitors of Clostridium botulinum neurotoxins. Infectious Disorders - Drug Targets 2007; 7: 47-57.
    • (2007) Infectious Disorders - Drug Targets , vol.7 , pp. 47-57
    • Cai, S.1    Singh, B.R.2
  • 154
    • 41849089323 scopus 로고    scopus 로고
    • Single microbead SELEX for efficient ssDNA aptamer generation against botulinum neurotoxin
    • Tok JB, Fischer NO. Single microbead SELEX for efficient ssDNA aptamer generation against botulinum neurotoxin. Chem Commun 2008; 28: 1883-5.
    • (2008) Chem Commun , vol.28 , pp. 1883-1885
    • Tok, J.B.1    Fischer, N.O.2
  • 156
    • 0018951535 scopus 로고
    • Botulinum injection into extraocular muscles as an alternative to strabismus surgery
    • Scott AB. Botulinum injection into extraocular muscles as an alternative to strabismus surgery. Opthalmology 1980; 87: 1044-9.
    • (1980) Opthalmology , vol.87 , pp. 1044-1049
    • Scott, A.B.1
  • 157
    • 0019761968 scopus 로고
    • Botulinum toxin injection of eye muscles to correct strabismus
    • Scott AB. Botulinum toxin injection of eye muscles to correct strabismus. Trans Am Opthalmol Soc 1981; 79: 734-70.
    • (1981) Trans Am Opthalmol Soc , vol.79 , pp. 734-770
    • Scott, A.B.1
  • 158
    • 0030853667 scopus 로고    scopus 로고
    • Botulinum toxin type B: A double-blind, placebo-controlled, safety and efficacy study in cervical dystonia
    • Lew MF, Adornato BT, Duane DD, Dykstra DD, Factor SA, Massey JM, et al. Botulinum toxin type B: A double-blind, placebo-controlled, safety and efficacy study in cervical dystonia. Neurology 1997; 49: 701-7.
    • (1997) Neurology , vol.49 , pp. 701-707
    • Lew, M.F.1    Adornato, B.T.2    Duane, D.D.3    Dykstra, D.D.4    Factor, S.A.5    Massey, J.M.6
  • 159
    • 0029073061 scopus 로고
    • Comparison of therapeutic efficacies of type A and F botulinum toxins for blepharospasm: A double-blind, controlled study
    • Mezaki T, Kaji R, Kohara N, Fujii H, Katayama M, Shimizu T, et al. Comparison of therapeutic efficacies of type A and F botulinum toxins for blepharospasm: A double-blind, controlled study. Neurology 1995; 45: 506-8.
    • (1995) Neurology , vol.45 , pp. 506-508
    • Mezaki, T.1    Kaji, R.2    Kohara, N.3    Fujii, H.4    Katayama, M.5    Shimizu, T.6
  • 160
    • 0026532292 scopus 로고
    • In vitro microelectrode study of neuromuscular transmission in a case of botulism
    • Maselli RA, Burnett ME, Tonsgard JH. In vitro microelectrode study of neuromuscular transmission in a case of botulism. Muscle Nerve 1992;15:273-6.
    • (1992) Muscle Nerve , vol.15 , pp. 273-276
    • Maselli, R.A.1    Burnett, M.E.2    Tonsgard, J.H.3
  • 161
    • 0036220846 scopus 로고    scopus 로고
    • Respective potencies of Botox® and Dysport®: A double blind, randomised, crossover study in cervical dystonia
    • Ranoux D, Gury C, Fondarai J, Mas JL, Zuber M. Respective potencies of Botox® and Dysport®: A double blind, randomised, crossover study in cervical dystonia. J Neurol Neurosurg Psychiatry 2002; 72: 459-62.
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 459-462
    • Ranoux, D.1    Gury, C.2    Fondarai, J.3    Mas, J.L.4    Zuber, M.5
  • 162
    • 3242745955 scopus 로고    scopus 로고
    • Clinical comparability of marketed formulations of botulinum toxin
    • Sampaio C, Costa J, Ferreira JJ. Clinical comparability of marketed formulations of botulinum toxin. Mov Disord 2004; 19: S129-36.
    • (2004) Mov Disord , vol.19
    • Sampaio, C.1    Costa, J.2    Ferreira, J.J.3
  • 163
    • 36549049448 scopus 로고    scopus 로고
    • Pharmacology of therapeutic botulinum toxin preparations
    • Dressler D, Benecke R. Pharmacology of therapeutic botulinum toxin preparations. Disabil Rehabil 2007; 29: 1761-8.
    • (2007) Disabil Rehabil , vol.29 , pp. 1761-1768
    • Dressler, D.1    Benecke, R.2
  • 164
    • 34047207959 scopus 로고    scopus 로고
    • Botulinum neurotoxin type A free of complexing proteins (Xeomin) in focal dystonia
    • Jost WH, Blumel J, Grafe S. Botulinum neurotoxin type A free of complexing proteins (Xeomin) in focal dystonia. Drugs 2007; 67: 669-83.
    • (2007) Drugs , vol.67 , pp. 669-683
    • Jost, W.H.1    Blumel, J.2    Grafe, S.3
  • 165
    • 33747161909 scopus 로고    scopus 로고
    • Botulinum toxin therapy for cervical dystonia
    • Jankovic J. Botulinum toxin therapy for cervical dystonia. Neurotox Res 2006; 9: 145-8.
    • (2006) Neurotox Res , vol.9 , pp. 145-148
    • Jankovic, J.1
  • 166
    • 43149099933 scopus 로고    scopus 로고
    • Assessment: Botulinum neurotoxin for the treatment of movement disorders (an evidence-based review)
    • Simpson DM, Gracies JM, Graham HK, Miyasaki JM, Naumann M, Russman B, et al. Assessment: Botulinum neurotoxin for the treatment of movement disorders (an evidence-based review). Neurology 2008; 70: 1691-8.
    • (2008) Neurology , vol.70 , pp. 1691-1698
    • Simpson, D.M.1    Gracies, J.M.2    Graham, H.K.3    Miyasaki, J.M.4    Naumann, M.5    Russman, B.6
  • 167
    • 33645108646 scopus 로고    scopus 로고
    • Botulinum toxin therapy of hemifacial spasm: Comparing different therapeutic preparations
    • Frei K, Truong DD, Dressler D. Botulinum toxin therapy of hemifacial spasm: comparing different therapeutic preparations. Eur J Neurol 2006; 13: 30-5.
    • (2006) Eur J Neurol , vol.13 , pp. 30-35
    • Frei, K.1    Truong, D.D.2    Dressler, D.3
  • 168
    • 3242780906 scopus 로고    scopus 로고
    • Botulinum toxin treatment of secretory disorders
    • Naumann M, Jost W. Botulinum toxin treatment of secretory disorders. Mov Disord 2004; 19: S137-41.
    • (2004) Mov Disord , vol.19
    • Naumann, M.1    Jost, W.2
  • 169
    • 0035849562 scopus 로고    scopus 로고
    • A randomized, double masked, controlled trial of botulinum toxin type A in essential hand tremor
    • Brin MF, Lyons KE, Doucette J, Adler CH, Caviness JN, Comella CL, et al. A randomized, double masked, controlled trial of botulinum toxin type A in essential hand tremor. Neurology 2001; 56: 1523-8.
    • (2001) Neurology , vol.56 , pp. 1523-1528
    • Brin, M.F.1    Lyons, K.E.2    Doucette, J.3    Adler, C.H.4    Caviness, J.N.5    Comella, C.L.6
  • 170
    • 0037337557 scopus 로고    scopus 로고
    • Botulinum toxin type A therapy in chronic pain disorders
    • Lang AM. Botulinum toxin type A therapy in chronic pain disorders. Arch Phys Med Rehabil 2003; 84: S69-73.
    • (2003) Arch Phys Med Rehabil , vol.84
    • Lang, A.M.1
  • 171
    • 0033389137 scopus 로고    scopus 로고
    • An update on the treatment of detrusor-sphincter dyssynergia with botulinum toxin type A
    • Schurch B, Schmid DM, Knapp PA. An update on the treatment of detrusor-sphincter dyssynergia with botulinum toxin type A. Eur J Neurol 2007; 6: S83-9.
    • (2007) Eur J Neurol , vol.6
    • Schurch, B.1    Schmid, D.M.2    Knapp, P.A.3
  • 172
    • 33845961031 scopus 로고    scopus 로고
    • Botulinum toxin in ophthalmology
    • Dutton JJ, Fowler AM. Botulinum toxin in ophthalmology. Surv Ophthalmol 2007; 52: 13-31.
    • (2007) Surv Ophthalmol , vol.52 , pp. 13-31
    • Dutton, J.J.1    Fowler, A.M.2
  • 173
    • 33749986106 scopus 로고    scopus 로고
    • Update on botulinum toxin
    • Flynn TC. Update on botulinum toxin. Semin Cutan Med Surg 2006; 25: 115-21.
    • (2006) Semin Cutan Med Surg , vol.25 , pp. 115-121
    • Flynn, T.C.1
  • 174
    • 33751021098 scopus 로고    scopus 로고
    • Why the most potent toxin may heal anal fissure
    • Madalinski M, Chodorowski Z. Why the most potent toxin may heal anal fissure. Adv Ther 2006; 23: 627-34.
    • (2006) Adv Ther , vol.23 , pp. 627-634
    • Madalinski, M.1    Chodorowski, Z.2
  • 175
    • 16244387919 scopus 로고    scopus 로고
    • Botulinum toxin in the treatment of refractory vaginismus
    • Ghazizadeh S, Nikzad M. Botulinum toxin in the treatment of refractory vaginismus. Obstet Gynecol 2004; 104: 922-5.
    • (2004) Obstet Gynecol , vol.104 , pp. 922-925
    • Ghazizadeh, S.1    Nikzad, M.2
  • 177
    • 34247379132 scopus 로고    scopus 로고
    • The emerging role of botulinum toxin in the treatment of temporomandibular disorders
    • Song PC, Schwartz J, Blitzer A. The emerging role of botulinum toxin in the treatment of temporomandibular disorders. Oral Dis 2007; 13: 253-60.
    • (2007) Oral Dis , vol.13 , pp. 253-260
    • Song, P.C.1    Schwartz, J.2    Blitzer, A.3
  • 178
    • 0000810225 scopus 로고    scopus 로고
    • Botulinum toxin: Historical perspective and potential new indications
    • Jankovic J, Brin MF. Botulinum toxin: Historical perspective and potential new indications. Muscle Nerve 1997; 20: S129-45.
    • (1997) Muscle Nerve , vol.20
    • Jankovic, J.1    Brin, M.F.2
  • 179
    • 0030963474 scopus 로고    scopus 로고
    • The management of hyperfunctional facial lines with botulinum toxin. A collaborative study of 210 injection sites in 162 patients
    • Blitzer A, Binder WJ, Aviv JE, Keen MS, Brin MF. The management of hyperfunctional facial lines with botulinum toxin. A collaborative study of 210 injection sites in 162 patients. Arch Otolaryngol 1997; 123: 389-92.
    • (1997) Arch Otolaryngol , vol.123 , pp. 389-392
    • Blitzer, A.1    Binder, W.J.2    Aviv, J.E.3    Keen, M.S.4    Brin, M.F.5
  • 180
    • 16644376459 scopus 로고    scopus 로고
    • Proper dose, preparation, and storage of botulinum neurotoxin serotype A
    • Anderson ER Jr. Proper dose, preparation, and storage of botulinum neurotoxin serotype A. Am J Health Syst Pharm 2004; 61 (22 Suppl 6): S24-29.
    • (2004) Am J Health Syst Pharm , vol.61 , Issue.22 SUPPL. 6
    • Anderson Jr., E.R.1
  • 181
    • 37349031503 scopus 로고    scopus 로고
    • A randomized pilot study comparing the action halos of two commercial preparations of botulinum toxin type A
    • Hexsel D, Dal'Forno T, Hexsel C, Do Prado DZ, Lima MM. A randomized pilot study comparing the action halos of two commercial preparations of botulinum toxin type A. Dermatol Surg 2008; 34: 52-9.
    • (2008) Dermatol Surg , vol.34 , pp. 52-59
    • Hexsel, D.1    Dal'Forno, T.2    Hexsel, C.3    Do Prado, D.Z.4    Lima, M.M.5
  • 183
    • 0033800350 scopus 로고    scopus 로고
    • A conjugate composed of nerve growth factor coupled to a non-toxic derivative of Clostridium botulinum neurotoxin type A can inhibit neurotransmitter release in vitro
    • Chaddock JA, Purkiss JR, Duggan MJ, Quinn CP, Shone CC, Foster KA. A conjugate composed of nerve growth factor coupled to a non-toxic derivative of Clostridium botulinum neurotoxin type A can inhibit neurotransmitter release in vitro. Growth Fact 2000; 18: 147-55.
    • (2000) Growth Fact , vol.18 , pp. 147-155
    • Chaddock, J.A.1    Purkiss, J.R.2    Duggan, M.J.3    Quinn, C.P.4    Shone, C.C.5    Foster, K.A.6
  • 184
    • 0033731911 scopus 로고    scopus 로고
    • Identification of the characteristics that underlie botulinum toxin potency: Implications for designing novel drugs
    • Simpson LL. Identification of the characteristics that underlie botulinum toxin potency: Implications for designing novel drugs. Biochimie 2000; 82: 943-53.
    • (2000) Biochimie , vol.82 , pp. 943-953
    • Simpson, L.L.1


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