A conjugate composed of nerve growth factor coupled to a non-toxic derivative of Clostridium botulinum neurotoxin type A can inhibit neurotransmitter release in vitro

Growth Factors

Volumn 18, Issue 2, 2000, Pages 147-155

  Chaddock, J A ^a   Purkiss, J R ^a   Duggan, M J ^a   Quinn, C P ^a   Shone, C C ^a   Foster, K A ^a  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Botulinum toxin type A; Nerve growth factor; PC12 cells; Synaptosomal associated protein 25

Indexed keywords

BOTULINUM TOXIN A; DOCKING PROTEIN; HYBRID PROTEIN; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CATALYSIS; CELL STRAIN; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG TARGETING; IN VITRO STUDY; INTERNALIZATION; NEUROMUSCULAR SYNAPSE; NEUROTRANSMITTER RELEASE; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TRANSPORT; RAT; RECEPTOR BINDING; TOXIN SYNTHESIS;

ANIMALIA; CLOSTRIDIUM BOTULINUM;

EID: 0033800350     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.3109/08977190009003240     Document Type: Article

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