메뉴 건너뛰기




Volumn 16, Issue 3, 2009, Pages 367-375

An adenoviral vector-based mucosal vaccine is effective in protection against botulism

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; EXOENZYME C3; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; NEUTRALIZING ANTIBODY;

EID: 62549084249     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2008.181     Document Type: Article
Times cited : (34)

References (54)
  • 1
    • 33744542067 scopus 로고    scopus 로고
    • Botulism: The many faces of botulinum toxin and its potential for bioterrorism
    • Villar RG, Elliott SP, Davenport KM. Botulism: The many faces of botulinum toxin and its potential for bioterrorism. Infect Dis Clin North Am 2006; 20: 313-327.
    • (2006) Infect Dis Clin North Am , vol.20 , pp. 313-327
    • Villar, R.G.1    Elliott, S.P.2    Davenport, K.M.3
  • 2
    • 0036053928 scopus 로고    scopus 로고
    • Bioterriorism: From threat to reality
    • Atlas RM. Bioterriorism: From threat to reality. Annu Rev Microbiol 2002; 56: 167-185.
    • (2002) Annu Rev Microbiol , vol.56 , pp. 167-185
    • Atlas, R.M.1
  • 3
    • 0032709597 scopus 로고    scopus 로고
    • The immunogenicity in humans of a botulinum type F vaccine
    • Montgomery VA, Makuch RS, Brown JE, Hack DC. The immunogenicity in humans of a botulinum type F vaccine. Vaccine 1999; 18: 728-735.
    • (1999) Vaccine , vol.18 , pp. 728-735
    • Montgomery, V.A.1    Makuch, R.S.2    Brown, J.E.3    Hack, D.C.4
  • 5
    • 0038544028 scopus 로고    scopus 로고
    • DNA vaccination protects against botulinum neurotoxin type F
    • Bennett AM, Perkins SD, Holley JL. DNA vaccination protects against botulinum neurotoxin type F. Vaccine 2003; 21: 3110-3117.
    • (2003) Vaccine , vol.21 , pp. 3110-3117
    • Bennett, A.M.1    Perkins, S.D.2    Holley, J.L.3
  • 6
    • 2342510157 scopus 로고    scopus 로고
    • Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity
    • Segelke B, Knapp M, Kadkhodayan S, Balhorn R, Rupp B. Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity. Proc Natl Acad Sci USA 2004; 101: 6888-6893.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6888-6893
    • Segelke, B.1    Knapp, M.2    Kadkhodayan, S.3    Balhorn, R.4    Rupp, B.5
  • 7
    • 0038475597 scopus 로고    scopus 로고
    • Expression of HC subunits from Clostridium botulinum types C and D and their evaluation as candidate vaccine antigens in mice
    • Woodward LA, Arimitsu H, Hirst R, Oguma K. Expression of HC subunits from Clostridium botulinum types C and D and their evaluation as candidate vaccine antigens in mice. Infect Immun 2003; 71: 2941-2944.
    • (2003) Infect Immun , vol.71 , pp. 2941-2944
    • Woodward, L.A.1    Arimitsu, H.2    Hirst, R.3    Oguma, K.4
  • 8
    • 0033748727 scopus 로고    scopus 로고
    • Development of vaccines for prevention of botulism
    • Byrne MP, Smith LA. Development of vaccines for prevention of botulism. Biochimie 2000; 82: 955-966.
    • (2000) Biochimie , vol.82 , pp. 955-966
    • Byrne, M.P.1    Smith, L.A.2
  • 9
    • 0031422145 scopus 로고    scopus 로고
    • Immune recognition of botulinum neurotoxin type A: Regions recognized by T cells and antibodies against the protective H(C) fragment (residues 855-1296) of the toxin
    • Oshima M, Hayakari M, Middlebrook JL, Atassi MZ. Immune recognition of botulinum neurotoxin type A: Regions recognized by T cells and antibodies against the protective H(C) fragment (residues 855-1296) of the toxin. Mol Immunol 1997; 34: 1031-1040.
    • (1997) Mol Immunol , vol.34 , pp. 1031-1040
    • Oshima, M.1    Hayakari, M.2    Middlebrook, J.L.3    Atassi, M.Z.4
  • 10
    • 34247325141 scopus 로고    scopus 로고
    • Protection with recombinant Clostridium botulinum C1 and D binding domain subunit (Hc) vaccines against C and D neurotoxins
    • Webb RP, Smith TJ, Wright PM, Montgomery VA, Meagher MM, Smith LA. Protection with recombinant Clostridium botulinum C1 and D binding domain subunit (Hc) vaccines against C and D neurotoxins. Vaccine 2007; 25: 4273-4282.
    • (2007) Vaccine , vol.25 , pp. 4273-4282
    • Webb, R.P.1    Smith, T.J.2    Wright, P.M.3    Montgomery, V.A.4    Meagher, M.M.5    Smith, L.A.6
  • 11
    • 0031658344 scopus 로고    scopus 로고
    • Purification, potency, and efficacy of the botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate
    • Byrne MP, Smith TJ, Montgomery VA, Smith LA. Purification, potency, and efficacy of the botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate. Infect Immun 1998; 66: 4817-4822.
    • (1998) Infect Immun , vol.66 , pp. 4817-4822
    • Byrne, M.P.1    Smith, T.J.2    Montgomery, V.A.3    Smith, L.A.4
  • 12
    • 0033023671 scopus 로고    scopus 로고
    • Structure, activity, and immune (T and B cell) recognition of botulinum neurotoxins
    • Atassi MZ, Oshima M. Structure, activity, and immune (T and B cell) recognition of botulinum neurotoxins. Crit Rev Immunol 1999; 19 219-260.
    • (1999) Crit Rev Immunol , vol.19 , pp. 219-260
    • Atassi, M.Z.1    Oshima, M.2
  • 13
    • 34249879558 scopus 로고    scopus 로고
    • Trivalent vaccine against botulinum toxin serotypes A, B, and E that can be administered by the mucosal route
    • Ravichandran E, Al-Saleem FH, Ancharski DM, Elias MD, Singh AK, Shamim M et al. Trivalent vaccine against botulinum toxin serotypes A, B, and E that can be administered by the mucosal route. Infect Immun 2007; 75: 3043-3054.
    • (2007) Infect Immun , vol.75 , pp. 3043-3054
    • Ravichandran, E.1    Al-Saleem, F.H.2    Ancharski, D.M.3    Elias, M.D.4    Singh, A.K.5    Shamim, M.6
  • 14
    • 38049093742 scopus 로고    scopus 로고
    • Botulinum neurotoxin vaccines: Past, present, and future
    • Smith LA, Rusnak JM. Botulinum neurotoxin vaccines: Past, present, and future. Crit Rev Immunol 2007; 27: 303-318.
    • (2007) Crit Rev Immunol , vol.27 , pp. 303-318
    • Smith, L.A.1    Rusnak, J.M.2
  • 15
    • 25444446822 scopus 로고    scopus 로고
    • Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E
    • Baldwin MR, Tepp WH, Pier CL, Bradshaw M, Ho M, Wilson BA et al. Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E. Infect Immun 2005; 73: 6998-7005.
    • (2005) Infect Immun , vol.73 , pp. 6998-7005
    • Baldwin, M.R.1    Tepp, W.H.2    Pier, C.L.3    Bradshaw, M.4    Ho, M.5    Wilson, B.A.6
  • 17
    • 0034056247 scopus 로고    scopus 로고
    • Fermentation, purification, and efficacy of a recombinant vaccine candidate against botulinum neurotoxin type F from Pichia pastoris
    • Byrne MP, Titball RW, Holley J, Smith LA. Fermentation, purification, and efficacy of a recombinant vaccine candidate against botulinum neurotoxin type F from Pichia pastoris. Protein Expr Purif 2000; 18: 327-337.
    • (2000) Protein Expr Purif , vol.18 , pp. 327-337
    • Byrne, M.P.1    Titball, R.W.2    Holley, J.3    Smith, L.A.4
  • 18
    • 33744923162 scopus 로고    scopus 로고
    • Recombinant C fragment of botulinum neurotoxin B serotype (rBoNTB (HC)) immune response and protection in the rhesus monkey
    • Boles J,West M, Montgomery V, Tammariello R, Pitt ML, Gibbs P et al Recombinant C fragment of botulinum neurotoxin B serotype (rBoNTB (HC)) immune response and protection in the rhesus monkey. Toxicon 2006; 47: 877-884.
    • (2006) Toxicon , vol.47 , pp. 877-884
    • Boles, J.1    West, M.2    Montgomery, V.3    Tammariello, R.4    Pitt, M.L.5    Gibbs, P.6
  • 19
    • 0034666747 scopus 로고    scopus 로고
    • Cloning, expression and evaluation of a recombinant sub-unit vaccine against Clostridium botulinum type F toxin
    • Holley JL, Elmore M, Mauchline M, Minton N, Titball RW. Cloning, expression and evaluation of a recombinant sub-unit vaccine against Clostridium botulinum type F toxin. Vaccine 2000; 19: 288-297.
    • (2000) Vaccine , vol.19 , pp. 288-297
    • Holley, J.L.1    Elmore, M.2    Mauchline, M.3    Minton, N.4    Titball, R.W.5
  • 20
    • 0034876256 scopus 로고    scopus 로고
    • Candidate vaccine against botulinum neurotoxin serotype A derived from a Venezuelan equine encephalitis virus vector system
    • Lee JS, Pushko P, Parker MD, Dertzbaugh MT, Smith LA, Smith JF. Candidate vaccine against botulinum neurotoxin serotype A derived from a Venezuelan equine encephalitis virus vector system. Infect Immun 2001; 69: 5709-5715.
    • (2001) Infect Immun , vol.69 , pp. 5709-5715
    • Lee, J.S.1    Pushko, P.2    Parker, M.D.3    Dertzbaugh, M.T.4    Smith, L.A.5    Smith, J.F.6
  • 21
    • 31844448804 scopus 로고    scopus 로고
    • Development of nonhuman adenoviruses as vaccine vectors
    • Bangari DS, Mittal SK. Development of nonhuman adenoviruses as vaccine vectors. Vaccine 2006; 24: 849-862.
    • (2006) Vaccine , vol.24 , pp. 849-862
    • Bangari, D.S.1    Mittal, S.K.2
  • 22
    • 4644318756 scopus 로고    scopus 로고
    • Adenoviruses as vaccine vectors
    • Tatsis N, Ertl HC. Adenoviruses as vaccine vectors. Mol Ther 2004; 10: 616-629.
    • (2004) Mol Ther , vol.10 , pp. 616-629
    • Tatsis, N.1    Ertl, H.C.2
  • 23
    • 0034730581 scopus 로고    scopus 로고
    • Adenoviruses as vectors for delivering vaccines to mucosal surfaces
    • Babiuk LA, Tikoo SK. Adenoviruses as vectors for delivering vaccines to mucosal surfaces. J Biotechnol 2000; 83: 105-113.
    • (2000) J Biotechnol , vol.83 , pp. 105-113
    • Babiuk, L.A.1    Tikoo, S.K.2
  • 24
    • 33845290569 scopus 로고    scopus 로고
    • A new complementing cell line for replication-incompetent E1-deleted adenovirus propagation
    • Xu Q, Arevalo MT, Pichichero ME, Zeng M. A new complementing cell line for replication-incompetent E1-deleted adenovirus propagation. Cytotechnology 2006; 51: 133-140.
    • (2006) Cytotechnology , vol.51 , pp. 133-140
    • Xu, Q.1    Arevalo, M.T.2    Pichichero, M.E.3    Zeng, M.4
  • 25
    • 32144439525 scopus 로고    scopus 로고
    • Development of adenoviral-vector-based pandemic influenza vaccine against antigenically distinct human H5N1 strains in mice
    • Hoelscher MA, Garg S, Bangari DS, Belser JA, Lu X, Stephenson I et al Development of adenoviral-vector-based pandemic influenza vaccine against antigenically distinct human H5N1 strains in mice. Lancet 2006; 367: 475-481.
    • (2006) Lancet , vol.367 , pp. 475-481
    • Hoelscher, M.A.1    Garg, S.2    Bangari, D.S.3    Belser, J.A.4    Lu, X.5    Stephenson, I.6
  • 26
    • 34250360726 scopus 로고    scopus 로고
    • Adenovirus-based vaccine prevents pneumonia in ferrets challenged with the SARS coronavirus and stimulates robust immune responses in macaques
    • Kobinger GP, Figueredo JM, Rowe T, Zhi Y, Gao G, Sanmiguel JC et al Adenovirus-based vaccine prevents pneumonia in ferrets challenged with the SARS coronavirus and stimulates robust immune responses in macaques. Vaccine 2007; 25: 5220-5231.
    • (2007) Vaccine , vol.25 , pp. 5220-5231
    • Kobinger, G.P.1    Figueredo, J.M.2    Rowe, T.3    Zhi, Y.4    Gao, G.5    Sanmiguel, J.C.6
  • 27
    • 33846087269 scopus 로고    scopus 로고
    • Efficient protein boosting after plasmid DNA or recombinant adenovirus immunization with HIV-1 vaccine constructs
    • Shu Y, Winfrey S, Yang ZY, Xu L, Rao SS, Srivastava I et al. Efficient protein boosting after plasmid DNA or recombinant adenovirus immunization with HIV-1 vaccine constructs. Vaccine 2007; 25 1398-1408.
    • (2007) Vaccine , vol.25 , pp. 1398-1408
    • Shu, Y.1    Winfrey, S.2    Yang, Z.Y.3    Xu, L.4    Rao, S.S.5    Srivastava, I.6
  • 28
    • 34250891279 scopus 로고    scopus 로고
    • Experimental immunization of cats with a recombinant rabies-canine adenovirus vaccine elicits a long-lasting neutralizing antibody response against rabies
    • Hu RL, Liu Y, Zhang SF, Zhang F, Fooks AR. Experimental immunization of cats with a recombinant rabies-canine adenovirus vaccine elicits a long-lasting neutralizing antibody response against rabies. Vaccine 2007; 25: 5301-5307.
    • (2007) Vaccine , vol.25 , pp. 5301-5307
    • Hu, R.L.1    Liu, Y.2    Zhang, S.F.3    Zhang, F.4    Fooks, A.R.5
  • 29
    • 33746632535 scopus 로고    scopus 로고
    • Intranasal boosting with an adenovirus-vectored vaccine markedly enhances protection by parenteral Mycobacterium bovis BCG immunization against pulmonary tuberculosis
    • Santosuosso M, McCormick S, Zhang X, Zganiacz A, Xing Z. Intranasal boosting with an adenovirus-vectored vaccine markedly enhances protection by parenteral Mycobacterium bovis BCG immunization against pulmonary tuberculosis. Infect Immun 2006; 74: 4634-4643.
    • (2006) Infect Immun , vol.74 , pp. 4634-4643
    • Santosuosso, M.1    McCormick, S.2    Zhang, X.3    Zganiacz, A.4    Xing, Z.5
  • 30
    • 29544437444 scopus 로고    scopus 로고
    • N-fragment of edema factor as a candidate antigen for immunization against anthrax
    • Zeng M, Xu Q, Hesek ED, Pichichero ME. N-fragment of edema factor as a candidate antigen for immunization against anthrax. Vaccine 2006; 24: 662-670.
    • (2006) Vaccine , vol.24 , pp. 662-670
    • Zeng, M.1    Xu, Q.2    Hesek, E.D.3    Pichichero, M.E.4
  • 31
    • 34848907990 scopus 로고    scopus 로고
    • Protective immunity against botulism provided by a single dose vaccination with an adenovirus-vectored vaccine
    • Zeng M, Xu Q, Elias M, Pichichero ME, Simpson LL, Smith LA. Protective immunity against botulism provided by a single dose vaccination with an adenovirus-vectored vaccine. Vaccine 2007; 25: 7540-7548.
    • (2007) Vaccine , vol.25 , pp. 7540-7548
    • Zeng, M.1    Xu, Q.2    Elias, M.3    Pichichero, M.E.4    Simpson, L.L.5    Smith, L.A.6
  • 33
    • 4844230030 scopus 로고    scopus 로고
    • Clostridium botulinum and the clinical laboratorian: A detailed review of botulism, including biological warfare ramifications of botulinum toxin
    • Caya JG, Agni R, Miller JE. Clostridium botulinum and the clinical laboratorian: A detailed review of botulism, including biological warfare ramifications of botulinum toxin. Arch Pathol Lab Med 2004; 128: 653-662.
    • (2004) Arch Pathol Lab Med , vol.128 , pp. 653-662
    • Caya, J.G.1    Agni, R.2    Miller, J.E.3
  • 36
    • 33749529135 scopus 로고    scopus 로고
    • Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A
    • Maddaloni M, Staats HF, Mierzejewska D, Hoyt T, Robinson A, Callis G et al. Mucosal vaccine targeting improves onset of mucosal and systemic immunity to botulinum neurotoxin A. J Immunol 2006; 177: 5524-5532.
    • (2006) J Immunol , vol.177 , pp. 5524-5532
    • Maddaloni, M.1    Staats, H.F.2    Mierzejewska, D.3    Hoyt, T.4    Robinson, A.5    Callis, G.6
  • 37
    • 0141570410 scopus 로고    scopus 로고
    • Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system
    • Lemiale F, Kong WP, Akyurek LM, Ling X, Huang Y, Chakrabarti BK et al Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system. J Virol 2003; 77: 10078-10087.
    • (2003) J Virol , vol.77 , pp. 10078-10087
    • Lemiale, F.1    Kong, W.P.2    Akyurek, L.M.3    Ling, X.4    Huang, Y.5    Chakrabarti, B.K.6
  • 38
    • 0038664390 scopus 로고    scopus 로고
    • Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene
    • Casimiro DR, Chen L, Fu TM, Evans RK, Caulfield MJ, Davies ME et al Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene. J Virol 2003; 77: 6305-6313.
    • (2003) J Virol , vol.77 , pp. 6305-6313
    • Casimiro, D.R.1    Chen, L.2    Fu, T.M.3    Evans, R.K.4    Caulfield, M.J.5    Davies, M.E.6
  • 39
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang Y, Li Q, Ertl HC, Wilson JM. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 1995; 69: 2004-2015.
    • (1995) J Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.M.4
  • 40
    • 0041707861 scopus 로고    scopus 로고
    • Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines
    • Barouch DH, McKay PF, Sumida SM, Santra S, Jackson SS, Gorgone DA et al. Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. J Virol 2003; 77: 8729-8735.
    • (2003) J Virol , vol.77 , pp. 8729-8735
    • Barouch, D.H.1    McKay, P.F.2    Sumida, S.M.3    Santra, S.4    Jackson, S.S.5    Gorgone, D.A.6
  • 41
    • 0033605093 scopus 로고    scopus 로고
    • The effect of pre-existing adenovirus-specific immunity on immune responses induced by recombinant adenovirus expressing glycoprotein D of bovine herpesvirus type 1
    • Papp Z, Babiuk LA, Baca-Estrada ME. The effect of pre-existing adenovirus-specific immunity on immune responses induced by recombinant adenovirus expressing glycoprotein D of bovine herpesvirus type 1. Vaccine 1999; 17: 933-943.
    • (1999) Vaccine , vol.17 , pp. 933-943
    • Papp, Z.1    Babiuk, L.A.2    Baca-Estrada, M.E.3
  • 42
    • 0037019923 scopus 로고    scopus 로고
    • Vaccination of puppies born to immune dams with a canine adenovirus-based vaccine protects against a canine distemper virus challenge
    • Fischer L, Tronel JP, Pardo-David C, Tanner P, Colombet G, Minke J et al. Vaccination of puppies born to immune dams with a canine adenovirus-based vaccine protects against a canine distemper virus challenge. Vaccine 2002; 20: 3485-3497.
    • (2002) Vaccine , vol.20 , pp. 3485-3497
    • Fischer, L.1    Tronel, J.P.2    Pardo-David, C.3    Tanner, P.4    Colombet, G.5    Minke, J.6
  • 44
    • 0034889160 scopus 로고    scopus 로고
    • AdEasy system made easier by selecting the viral backbone plasmid preceding homologous recombination
    • Zeng M, Smith SK, Siegel F, Shi Z, Van Kampen KR, Elmets CA et al. AdEasy system made easier by selecting the viral backbone plasmid preceding homologous recombination. Biotechniques 2001; 31: 260-262.
    • (2001) Biotechniques , vol.31 , pp. 260-262
    • Zeng, M.1    Smith, S.K.2    Siegel, F.3    Shi, Z.4    Van Kampen, K.R.5    Elmets, C.A.6
  • 45
    • 0025024715 scopus 로고
    • The complete nucleotide sequence of the gene coding for botulinum type C1 toxin in the C-ST phage genome
    • Kimura K, Fujii N, Tsuzuki K, Murakami T, Indoh T, Yokosawa N et al The complete nucleotide sequence of the gene coding for botulinum type C1 toxin in the C-ST phage genome. Biochem Biophys Res Commun 1990; 171: 1304-1311.
    • (1990) Biochem Biophys Res Commun , vol.171 , pp. 1304-1311
    • Kimura, K.1    Fujii, N.2    Tsuzuki, K.3    Murakami, T.4    Indoh, T.5    Yokosawa, N.6
  • 46
    • 32144438858 scopus 로고    scopus 로고
    • Mucosal immunization with recombinant MOMP genetically linked with modified cholera toxin confers protection against Chlamydia trachomatis infection
    • Singh SR, Hulett K, Pillai SR, Dennis VA, Oh MK, Scissum-Gunn K. Mucosal immunization with recombinant MOMP genetically linked with modified cholera toxin confers protection against Chlamydia trachomatis infection. Vaccine 2006; 24: 1213-1224.
    • (2006) Vaccine , vol.24 , pp. 1213-1224
    • Singh, S.R.1    Hulett, K.2    Pillai, S.R.3    Dennis, V.A.4    Oh, M.K.5    Scissum-Gunn, K.6
  • 47
    • 0025993760 scopus 로고
    • Distribution, persistence, and recall of serum and salivary antibody responses to peroral immunization with protein antigen I/II of Streptococcus mutans coupled to the cholera toxin B subunit
    • Russell MW, Wu HY. Distribution, persistence, and recall of serum and salivary antibody responses to peroral immunization with protein antigen I/II of Streptococcus mutans coupled to the cholera toxin B subunit. Infect Immun 1991; 59: 4061-4070.
    • (1991) Infect Immun , vol.59 , pp. 4061-4070
    • Russell, M.W.1    Wu, H.Y.2
  • 48
    • 34147175134 scopus 로고    scopus 로고
    • Protection against anthrax by needle-free mucosal immunization with human anthrax vaccine
    • Zeng M, Xu Q, Pichichero ME. Protection against anthrax by needle-free mucosal immunization with human anthrax vaccine. Vaccine 2007; 25: 3558-3594.
    • (2007) Vaccine , vol.25 , pp. 3558-3594
    • Zeng, M.1    Xu, Q.2    Pichichero, M.E.3
  • 49
    • 0037019886 scopus 로고    scopus 로고
    • Characterization of protective immune responses induced by nasal influenza vaccine containing mutant cholera toxin as a safe adjuvant (CT112K)
    • Watanabe I, Hagiwara Y, Kadowaki SE, Yoshikawa T, Komase K, Aizawa C et al. Characterization of protective immune responses induced by nasal influenza vaccine containing mutant cholera toxin as a safe adjuvant (CT112K). Vaccine 2002; 20: 3443-3455.
    • (2002) Vaccine , vol.20 , pp. 3443-3455
    • Watanabe, I.1    Hagiwara, Y.2    Kadowaki, S.E.3    Yoshikawa, T.4    Komase, K.5    Aizawa, C.6
  • 50
    • 2442711570 scopus 로고    scopus 로고
    • Vaccination with recombinant whole heavy chain fragments of Clostridium botulinum Type C and D neurotoxins
    • Arimitsu H, Lee JC, Sakaguchi Y, Hayakawa Y, Hayashi M, Nakaura M et al. Vaccination with recombinant whole heavy chain fragments of Clostridium botulinum Type C and D neurotoxins. Clin Diagn Lab Immunol 2004; 11: 496-502.
    • (2004) Clin Diagn Lab Immunol , vol.11 , pp. 496-502
    • Arimitsu, H.1    Lee, J.C.2    Sakaguchi, Y.3    Hayakawa, Y.4    Hayashi, M.5    Nakaura, M.6
  • 52
    • 0035164001 scopus 로고    scopus 로고
    • Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines
    • Shi Z, Zeng M, Yang G, Siegel F, Cain LJ, van Kampen KR et al. Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines. J Virol 2001; 75: 11474-11482.
    • (2001) J Virol , vol.75 , pp. 11474-11482
    • Shi, Z.1    Zeng, M.2    Yang, G.3    Siegel, F.4    Cain, L.J.5    van Kampen, K.R.6
  • 53
    • 0032813559 scopus 로고    scopus 로고
    • Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs
    • Harvey BG, Hackett NR, El-Sawy T, Rosengart TK, Hirschowitz EA, Lieberman MD et al. Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs. J Virol 1999; 73: 6729-6742.
    • (1999) J Virol , vol.73 , pp. 6729-6742
    • Harvey, B.G.1    Hackett, N.R.2    El-Sawy, T.3    Rosengart, T.K.4    Hirschowitz, E.A.5    Lieberman, M.D.6
  • 54
    • 13344286312 scopus 로고    scopus 로고
    • Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis
    • Zabner J, Ramsey BW, Meeker DP, Aitken ML, Balfour RP, Gibson RL et al. Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis. J Clin Invest 1996; 97: 1504-1511.
    • (1996) J Clin Invest , vol.97 , pp. 1504-1511
    • Zabner, J.1    Ramsey, B.W.2    Meeker, D.P.3    Aitken, M.L.4    Balfour, R.P.5    Gibson, R.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.