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Volumn 1806, Issue 2, 2010, Pages 268-274

TBX2 and TBX3: The special value for anticancer drug targets

Author keywords

TBX2; TBX3; Tumorigenesis

Indexed keywords

BELINOSTAT; BETA CATENIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; EARLY GROWTH RESPONSE FACTOR 1; FIBRONECTIN; GIVINOSTAT; HISTONE DEACETYLASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; N (2 AMINOPHENYL) 4 [4 (3 PYRIDINYL) 2 PYRIMIDINYLAMINOMETHYL]BENZAMIDE; PANOBINOSTAT; PCI 24781; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN C JUN; PROTEIN MDM2; PROTEIN P107; PROTEIN P53; RETINOBLASTOMA PROTEIN; ROMIDEPSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBX2; TRANSCRIPTION FACTOR TBX3; TRANSCRIPTION FACTOR TBX5; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UNINDEXED DRUG; UVOMORULIN; VALPROIC ACID; VORINOSTAT; WNT PROTEIN; T BOX TRANSCRIPTION FACTOR;

EID: 78649458007     PISSN: 0304419X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbcan.2010.07.001     Document Type: Review
Times cited : (50)

References (82)
  • 1
    • 0033119649 scopus 로고    scopus 로고
    • T-box genes: what they do and how they do it
    • Smith J. T-box genes: what they do and how they do it. Trends Genet. 1999, 15:154-158.
    • (1999) Trends Genet. , vol.15 , pp. 154-158
    • Smith, J.1
  • 2
    • 0033621059 scopus 로고    scopus 로고
    • Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome
    • He M., Wen L., Campbell C.E., Wu J.Y., Rao Y. Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome. Proc. Natl. Acad. Sci. USA 1999, 96:10212-10217.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10212-10217
    • He, M.1    Wen, L.2    Campbell, C.E.3    Wu, J.Y.4    Rao, Y.5
  • 3
    • 0031812415 scopus 로고    scopus 로고
    • Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter
    • Carreira S., Dexter T.J., Yavuzer U., Easty D.J., Goding C.R. Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter. Mol. Cell. Biol. 1998, 18:5099-5108.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5099-5108
    • Carreira, S.1    Dexter, T.J.2    Yavuzer, U.3    Easty, D.J.4    Goding, C.R.5
  • 4
    • 0001045827 scopus 로고
    • Sur la mortification spontanee de la queue che la souris nouveau-nee et sur l'existence d'un caractere (facteur) herediaire "non viable"
    • Dobrovolskaia-Zavadskaia N. Sur la mortification spontanee de la queue che la souris nouveau-nee et sur l'existence d'un caractere (facteur) herediaire "non viable". Crit. Rev. Soc. Biol. 1927, 97:114-116.
    • (1927) Crit. Rev. Soc. Biol. , vol.97 , pp. 114-116
    • Dobrovolskaia-Zavadskaia, N.1
  • 5
    • 0025062325 scopus 로고
    • Cloning of the T gene required in mesoderm formation in the mouse
    • Herrmann B.G., Labeit S., Poustka A., King T.R., Lehrach H. Cloning of the T gene required in mesoderm formation in the mouse. Nature 1990, 343:617-622.
    • (1990) Nature , vol.343 , pp. 617-622
    • Herrmann, B.G.1    Labeit, S.2    Poustka, A.3    King, T.R.4    Lehrach, H.5
  • 6
    • 0027129773 scopus 로고
    • A homology domain shared between Drosophila optomotor-blind and mouse Brachyury is involved in DNA binding
    • Pflugfelder G.O., Roth H., Poeck B. A homology domain shared between Drosophila optomotor-blind and mouse Brachyury is involved in DNA binding. Biochem. Biophys. Res. Commun. 1992, 186:918-925.
    • (1992) Biochem. Biophys. Res. Commun. , vol.186 , pp. 918-925
    • Pflugfelder, G.O.1    Roth, H.2    Poeck, B.3
  • 9
    • 0347417012 scopus 로고    scopus 로고
    • T-box genes in early embryogenesis
    • Showell C., Binder O., Conlon F.L. T-box genes in early embryogenesis. Dev. Dyn. 2004, 229:201-218.
    • (2004) Dev. Dyn. , vol.229 , pp. 201-218
    • Showell, C.1    Binder, O.2    Conlon, F.L.3
  • 13
    • 77949766590 scopus 로고    scopus 로고
    • The T-box transcription factor Tbx2: its role in development and possible implication in cancer
    • Abrahams A., Parker M.I., Prince S. The T-box transcription factor Tbx2: its role in development and possible implication in cancer. IUBMB Life 2010, 62:92-102.
    • (2010) IUBMB Life , vol.62 , pp. 92-102
    • Abrahams, A.1    Parker, M.I.2    Prince, S.3
  • 15
  • 16
    • 0029165111 scopus 로고
    • The T protein encoded by Brachyury is a tissue-specific transcription factor
    • Kispert A., Koschorz B., Herrmann B.G. The T protein encoded by Brachyury is a tissue-specific transcription factor. EMBO J. 1995, 14:4763-4772.
    • (1995) EMBO J. , vol.14 , pp. 4763-4772
    • Kispert, A.1    Koschorz, B.2    Herrmann, B.G.3
  • 17
    • 0035445835 scopus 로고    scopus 로고
    • Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome
    • Ghosh T.K., Packham E.A., Bonser A.J., Robinson T.E., Cross S.J., Brook J.D. Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome. Hum. Mol. Genet. 2001, 10:1983-1994.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1983-1994
    • Ghosh, T.K.1    Packham, E.A.2    Bonser, A.J.3    Robinson, T.E.4    Cross, S.J.5    Brook, J.D.6
  • 18
    • 0037135545 scopus 로고    scopus 로고
    • The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator
    • Lingbeek M.E., Jacobs J.J., van Lohuizen M. The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator. J. Biol. Chem. 2002, 277:26120-26127.
    • (2002) J. Biol. Chem. , vol.277 , pp. 26120-26127
    • Lingbeek, M.E.1    Jacobs, J.J.2    van Lohuizen, M.3
  • 20
    • 0039706410 scopus 로고    scopus 로고
    • Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor
    • Müller C.W., Herrmann B.G. Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor. Nature 1997, 389:884-888.
    • (1997) Nature , vol.389 , pp. 884-888
    • Müller, C.W.1    Herrmann, B.G.2
  • 21
    • 0036120604 scopus 로고    scopus 로고
    • Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome
    • Coll M., Seidman J.G., Müller C.W. Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome. Structure 2002, 10:343-356.
    • (2002) Structure , vol.10 , pp. 343-356
    • Coll, M.1    Seidman, J.G.2    Müller, C.W.3
  • 22
    • 29144512222 scopus 로고    scopus 로고
    • A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome
    • Murakami M., Nakagawa M., Olson E.N., Nakagawa O. A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome. Proc. Natl. Acad. Sci. USA 2005, 102:18034-18039.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 18034-18039
    • Murakami, M.1    Nakagawa, M.2    Olson, E.N.3    Nakagawa, O.4
  • 24
    • 0035937414 scopus 로고    scopus 로고
    • A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins
    • Lamolet B., Pulichino A.M., Lamonerie T., Gauthier Y., Brue T., Enjalbert A., Drouin J. A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins. Cell 2001, 104:849-859.
    • (2001) Cell , vol.104 , pp. 849-859
    • Lamolet, B.1    Pulichino, A.M.2    Lamonerie, T.3    Gauthier, Y.4    Brue, T.5    Enjalbert, A.6    Drouin, J.7
  • 29
    • 0035504693 scopus 로고    scopus 로고
    • A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome
    • Carlson H., Ota S., Campbell C.E., Hurlin P.J. A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome. Hum. Mol. Genet. 2001, 10:2403-2413.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2403-2413
    • Carlson, H.1    Ota, S.2    Campbell, C.E.3    Hurlin, P.J.4
  • 34
    • 3442883903 scopus 로고    scopus 로고
    • TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines
    • Fan W., Huang X., Chen C., Gray J., Huang T. TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines. Cancer Res. 2004, 64:5132-5139.
    • (2004) Cancer Res. , vol.64 , pp. 5132-5139
    • Fan, W.1    Huang, X.2    Chen, C.3    Gray, J.4    Huang, T.5
  • 35
    • 28544450672 scopus 로고    scopus 로고
    • Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients
    • Lomnytska M., Dubrovska A., Hellman U., Volodko N., Souchelnytskyi S. Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients. Int. J. Cancer 2006, 118:412-421.
    • (2006) Int. J. Cancer , vol.118 , pp. 412-421
    • Lomnytska, M.1    Dubrovska, A.2    Hellman, U.3    Volodko, N.4    Souchelnytskyi, S.5
  • 38
    • 4644307290 scopus 로고    scopus 로고
    • Met proto-oncogene and insulin-like growth factor binding protein 3 overexpression correlates with metastatic ability in well-differentiated pancreatic endocrine neoplasms
    • Hansel D.E., Rahman A., House M., Ashfaq R., Berg K., Yeo C.J., Maitra A. Met proto-oncogene and insulin-like growth factor binding protein 3 overexpression correlates with metastatic ability in well-differentiated pancreatic endocrine neoplasms. Clin. Cancer Res. 2004, 10:6152-6158.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6152-6158
    • Hansel, D.E.1    Rahman, A.2    House, M.3    Ashfaq, R.4    Berg, K.5    Yeo, C.J.6    Maitra, A.7
  • 39
    • 0029400966 scopus 로고
    • Identification, characterization, and localization to chromosome 17q21-22 of the human TBX2 homolog, member of a conserved developmental gene family
    • Law D.J., Gebuhr T., Garvey N., Agulnik S.I., Silver L.M. Identification, characterization, and localization to chromosome 17q21-22 of the human TBX2 homolog, member of a conserved developmental gene family. Mamm. Genome 1995, 6:793-797.
    • (1995) Mamm. Genome , vol.6 , pp. 793-797
    • Law, D.J.1    Gebuhr, T.2    Garvey, N.3    Agulnik, S.I.4    Silver, L.M.5
  • 40
    • 0035393582 scopus 로고    scopus 로고
    • Structural analysis of the 17q22-23 amplicon identifies several independent targets of amplification in breast cancer cell lines and tumors
    • Wu G., Sinclair C., Hinson S., Ingle J.N., Roche P.C., Couch F.J. Structural analysis of the 17q22-23 amplicon identifies several independent targets of amplification in breast cancer cell lines and tumors. Cancer Res. 2001, 61:4951-4955.
    • (2001) Cancer Res. , vol.61 , pp. 4951-4955
    • Wu, G.1    Sinclair, C.2    Hinson, S.3    Ingle, J.N.4    Roche, P.C.5    Couch, F.J.6
  • 42
    • 16844387097 scopus 로고    scopus 로고
    • Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas
    • Vance K.W., Carreira S., Brosch G., Goding C.R. Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas. Cancer Res. 2005, 65:2260-2268.
    • (2005) Cancer Res. , vol.65 , pp. 2260-2268
    • Vance, K.W.1    Carreira, S.2    Brosch, G.3    Goding, C.R.4
  • 43
    • 54249133490 scopus 로고    scopus 로고
    • Tbx3 represses E-cadherin expression and enhances melanoma invasiveness
    • Rodriguez M., Aladowicz E., Lanfrancone L., Goding C.R. Tbx3 represses E-cadherin expression and enhances melanoma invasiveness. Cancer Res. 2008, 68:7872-7881.
    • (2008) Cancer Res. , vol.68 , pp. 7872-7881
    • Rodriguez, M.1    Aladowicz, E.2    Lanfrancone, L.3    Goding, C.R.4
  • 46
    • 35048876778 scopus 로고    scopus 로고
    • A role for Tbx2 in the regulation of the alpha2(1) collagen gene in human fibroblasts
    • Teng H., Davis E., Abrahams A., Mowla S., Parker M.I., Prince S. A role for Tbx2 in the regulation of the alpha2(1) collagen gene in human fibroblasts. J. Cell. Biochem. 2007, 102:618-625.
    • (2007) J. Cell. Biochem. , vol.102 , pp. 618-625
    • Teng, H.1    Davis, E.2    Abrahams, A.3    Mowla, S.4    Parker, M.I.5    Prince, S.6
  • 47
    • 13244253702 scopus 로고    scopus 로고
    • Genes differentially expressed in human lung fibroblast cells transformed by glycidyl methacrylate
    • Yin X.J., Xu J.N., Zou C.Q., He F.S., Fang F.D. Genes differentially expressed in human lung fibroblast cells transformed by glycidyl methacrylate. Biomed. Environ. Sci. 2004, 17:432-441.
    • (2004) Biomed. Environ. Sci. , vol.17 , pp. 432-441
    • Yin, X.J.1    Xu, J.N.2    Zou, C.Q.3    He, F.S.4    Fang, F.D.5
  • 49
    • 0038277105 scopus 로고    scopus 로고
    • Tumor cell senescence in cancer treatment
    • Roninson I.B. Tumor cell senescence in cancer treatment. Cancer Res. 2003, 63:2705-2715.
    • (2003) Cancer Res. , vol.63 , pp. 2705-2715
    • Roninson, I.B.1
  • 50
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M., Lin A.W., McCurrach M.E., Beach D., Lowe S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997, 88:593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 51
    • 0032192153 scopus 로고    scopus 로고
    • Senescence of human fibroblasts induced by oncogenic Raf
    • Zhu J., Woods D., McMahon M., Bishop J.M. Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev. 1998, 12:2997-3007.
    • (1998) Genes Dev. , vol.12 , pp. 2997-3007
    • Zhu, J.1    Woods, D.2    McMahon, M.3    Bishop, J.M.4
  • 52
    • 0035500487 scopus 로고    scopus 로고
    • Cellular senescence as a tumor-suppressor mechanism
    • Campisi J. Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol. 2001, 11:S27-S31.
    • (2001) Trends Cell Biol. , vol.11
    • Campisi, J.1
  • 54
    • 0028849274 scopus 로고
    • P21 is necessary for the p53-mediated G1 arrest in human cancer cells
    • Waldman T., Kinzler K.W., Vogelstein B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 1995, 55:5187-5190.
    • (1995) Cancer Res. , vol.55 , pp. 5187-5190
    • Waldman, T.1    Kinzler, K.W.2    Vogelstein, B.3
  • 55
    • 0030011128 scopus 로고    scopus 로고
    • Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
    • Waldman T., Lengauer C., Kinzler K.W., Vogelstein B. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 1996, 381:713-716.
    • (1996) Nature , vol.381 , pp. 713-716
    • Waldman, T.1    Lengauer, C.2    Kinzler, K.W.3    Vogelstein, B.4
  • 57
    • 0037198695 scopus 로고    scopus 로고
    • Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation
    • Carlson H., Ota S., Song Y., Chen Y., Hurlin P.J. Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation. Oncogene 2002, 21:3827-3835.
    • (2002) Oncogene , vol.21 , pp. 3827-3835
    • Carlson, H.1    Ota, S.2    Song, Y.3    Chen, Y.4    Hurlin, P.J.5
  • 58
    • 1642396456 scopus 로고    scopus 로고
    • Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor
    • Prince S., Carreira S., Vance K.W., Abrahams A., Goding C.R. Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor. Cancer Res. 2004, 64:1669-1674.
    • (2004) Cancer Res. , vol.64 , pp. 1669-1674
    • Prince, S.1    Carreira, S.2    Vance, K.W.3    Abrahams, A.4    Goding, C.R.5
  • 61
    • 0043172452 scopus 로고    scopus 로고
    • P53- and Mdm2-independent repression of NF-kappa B transactivation by the ARF tumor suppressor
    • Rocha S., Campbell K.J., Perkins N.D. p53- and Mdm2-independent repression of NF-kappa B transactivation by the ARF tumor suppressor. Mol. Cell 2003, 12:15-25.
    • (2003) Mol. Cell , vol.12 , pp. 15-25
    • Rocha, S.1    Campbell, K.J.2    Perkins, N.D.3
  • 62
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell 1995, 81:323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 63
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family proteins
    • Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev. 1998, 12:2245-2262.
    • (1998) Genes Dev. , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 64
    • 0037052539 scopus 로고    scopus 로고
    • A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells
    • Ogawa H., Ishiguro K., Gaubatz S., Livingston D.M., Nakatani Y. A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. Science 2002, 296:1132-1136.
    • (2002) Science , vol.296 , pp. 1132-1136
    • Ogawa, H.1    Ishiguro, K.2    Gaubatz, S.3    Livingston, D.M.4    Nakatani, Y.5
  • 66
    • 0034306996 scopus 로고    scopus 로고
    • The Rb/E2F pathway: expanding roles and emerging paradigms
    • Harbour J.W., Dean D.C. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev. 2000, 14:2393-2409.
    • (2000) Genes Dev. , vol.14 , pp. 2393-2409
    • Harbour, J.W.1    Dean, D.C.2
  • 67
    • 0030031409 scopus 로고    scopus 로고
    • Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6
    • Chen P.L., Riley D.J., Chen-Kiang S., Lee W.H. Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6. Proc. Natl. Acad. Sci. USA 1996, 93:465-469.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 465-469
    • Chen, P.L.1    Riley, D.J.2    Chen-Kiang, S.3    Lee, W.H.4
  • 68
    • 0029830342 scopus 로고    scopus 로고
    • Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs
    • Chen P.L., Riley D.J., Chen Y., Lee W.H. Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. Genes Dev. 1996, 10:2794-2804.
    • (1996) Genes Dev. , vol.10 , pp. 2794-2804
    • Chen, P.L.1    Riley, D.J.2    Chen, Y.3    Lee, W.H.4
  • 71
    • 57349141873 scopus 로고    scopus 로고
    • Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2
    • Vormer T.L., Foijer F., Wielders C.L., te Riele H. Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2. Mol. Cell. Biol. 2008, 28:7263-7273.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 7263-7273
    • Vormer, T.L.1    Foijer, F.2    Wielders, C.L.3    te Riele, H.4
  • 72
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T., Clevers H. Wnt signalling in stem cells and cancer. Nature 2005, 434:843-850.
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 73
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006, 127:469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 74
    • 24944571050 scopus 로고    scopus 로고
    • Wnt signalling mediated by Tbx2b regulates cell migration during formation of the neural plate
    • Fong S., Emelyanov A., Teh C., Korzh V. Wnt signalling mediated by Tbx2b regulates cell migration during formation of the neural plate. Development 2005, 132:3587-3596.
    • (2005) Development , vol.132 , pp. 3587-3596
    • Fong, S.1    Emelyanov, A.2    Teh, C.3    Korzh, V.4
  • 75
    • 68549106083 scopus 로고    scopus 로고
    • E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer
    • Schmalhofer O., Brabletz S., Brabletz T. E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer. Cancer Metastasis Rev. 2009, 28:151-166.
    • (2009) Cancer Metastasis Rev. , vol.28 , pp. 151-166
    • Schmalhofer, O.1    Brabletz, S.2    Brabletz, T.3
  • 76
    • 30944446390 scopus 로고    scopus 로고
    • The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin
    • Baron V., Adamson E.D., Calogero A., Ragona G., Mercola D. The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin. Cancer Gene Ther. 2006, 13:115-124.
    • (2006) Cancer Gene Ther. , vol.13 , pp. 115-124
    • Baron, V.1    Adamson, E.D.2    Calogero, A.3    Ragona, G.4    Mercola, D.5
  • 77
    • 73949128107 scopus 로고    scopus 로고
    • Histone Deacetylase inhibitors in cancer therapy
    • Lane A.A., Chabner B.A. Histone Deacetylase inhibitors in cancer therapy. J. Clin. Oncol. 2009, 27:5459-5468.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 5459-5468
    • Lane, A.A.1    Chabner, B.A.2
  • 79
    • 0030961889 scopus 로고    scopus 로고
    • Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain
    • Selivanova G., Iotsova V., Okan I., Fritsche M., Ström M., Groner B., Grafström R.C., Wiman K.G. Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain. Nat. Med. 1997, 3:632-638.
    • (1997) Nat. Med. , vol.3 , pp. 632-638
    • Selivanova, G.1    Iotsova, V.2    Okan, I.3    Fritsche, M.4    Ström, M.5    Groner, B.6    Grafström, R.C.7    Wiman, K.G.8
  • 80
    • 0030615324 scopus 로고    scopus 로고
    • P21WAF1-derived peptides linked to an internalization peptide inhibit human cancer cell growth
    • Bonfanti M., Taverna S., Salmona M., D'Incalci M., Broggini M. p21WAF1-derived peptides linked to an internalization peptide inhibit human cancer cell growth. Cancer Res. 1997, 57:1442-1446.
    • (1997) Cancer Res. , vol.57 , pp. 1442-1446
    • Bonfanti, M.1    Taverna, S.2    Salmona, M.3    D'Incalci, M.4    Broggini, M.5
  • 81
    • 0032485025 scopus 로고    scopus 로고
    • Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule
    • Fåhraeus R., Laín S., Ball K.L., Lane D.P. Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule. Oncogene 1998, 16:587-596.
    • (1998) Oncogene , vol.16 , pp. 587-596
    • Fåhraeus, R.1    Laín, S.2    Ball, K.L.3    Lane, D.P.4
  • 82
    • 55249113736 scopus 로고    scopus 로고
    • TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice
    • Zhou Y., Du W., Koretsky T., Bagby G.C., Pang Q. TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice. Blood 2008, 112:2474-2483.
    • (2008) Blood , vol.112 , pp. 2474-2483
    • Zhou, Y.1    Du, W.2    Koretsky, T.3    Bagby, G.C.4    Pang, Q.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.