Stabilization of β-catenin affects mouse embryonic liver growth and hepatoblast fate

Hepatology

Volumn 47, Issue 1, 2008, Pages 247-258

  Decaens, Thomas ^a,b   Godard, Cécile ^a,b   De Reyniès, Aurélien ^c   Rickman, David S ^c   Tronche, François ^d   Couty, Jean Pierre ^a,b   Perret, Christine ^a,b   Colnot, Sabine ^a,b,e  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

^c Ligue Nationale Contre le Cancer   (France)

^d l'alimentation et l'Environnement   (France)

^e CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CRE RECOMBINASE; MESSENGER RNA; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE DUCT; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; COLON POLYPOSIS; CYCLIZATION; EMBRYO; EMBRYO DEATH; EMBRYO GROWTH; ENDODERM; FEMALE; GENE LOCUS; GRAFT RECIPIENT; GROWTH INHIBITION; HYPOPLASIA; IMMUNOLOCALIZATION; LETHALITY; LIVER DEVELOPMENT; LIVER GRAFT; MALE; MICROARRAY ANALYSIS; MORPHOGENESIS; MOUSE; NONHUMAN; PHENOTYPE; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; BETA CATENIN; CELL DIFFERENTIATION; EMBRYO LOSS; HEPATOCYTES; LIVER; MICE; MORPHOGENESIS; PHENOTYPE; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 38649093310     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21952     Document Type: Article

References (33)

1. Benhamouche S, Decaens T, Godard C, Chambrey R, Rickman DS, Moinard C, et al. Apc tumor suppressor gene is the "zonation-keeper" of mouse liver. Dev Cell 2006;10:759-770.
2. Colnot S, Decaens T, Niwa-Kawakita M, Godard C, Hamard G, Kahn A, et al. Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas. Proc Natl Acad Sci U S A 2004;101:17216-17221.
3. de La Coste A, Romagnolo B, Billuart P, Renard CA, Buendia MA, Soubrane O, et al. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Nad Acad Sci U S A 1998;95:8847-8851.
4. Ober EA, Verkade H, Field HA, Stainier DY. Mesodermal Wnt2b signalling positively regulates liver specification. Nature 2006;442:688-691.
5. Sekine S, Gutierrez PJ, Yu-Ang Lan B, Feng S, Hebrok M. Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy. HEPATOLOGY 2007;45:361-368.
6. Tan X, Behari J, Cieply B, Michalopoulos GK, Monga SP. Conditional deletion of beta-catenin reveals its role in liver growth and regeneration. Gastroenterology 2006; 131:1561-1572.
7. Finley KR, Tennessen J, Shawlot W. The mouse secreted frizzled-related protein 5 gene is expressed in the anterior visceral endoderm and foregut endoderm during early post-implantation development. Gene Expr Patterns 2003;3:681-684.
8. Zaret KS. Regulatory phases of early liver development: paradigms of organogenesis. Nat Rev Genet 2002;3:499-512.
9. Zhao R, Duncan SA. Embryonic development of the liver. HEPATOLOGY 2005;41:956-967.
10. Lemaigre FP. Development of the biliary tract. Mech Dev 2003;120:81-87.
11. Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006;127:469-480.
12. Kellendonk C, Opherk C, Anlag K, Schutz G, Tronche F. Hepatocyte-specific expression of Cre recombinase. Genesis 2000;26:151-153.
13. Leneuve P, Colnot S, Hamard G, Francis F, Niwa-Kawakita M, Giovannini M, et al. Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. Nucleic Acids Res 2003;31:e21.
14. Ovejero C, Cavard C, Perianin A, Hakvoort T, Vermeiden J, Godard C, et al. Identification of the leukocyte cell-derived chemotaxin 2 as a direct target gene of beta-catenin in the liver. HEPATOLOGY 2004;40:167-176.
15. Shiojiri N, Sugiyama Y. Immunolocalization of extracellular matrix components and integrins during mouse liver development. HEPATOLOGY 2004;40:346-355.
16. Clotman F, Jacquemin P, Plumb-Rudewiez N, Pierreux CE, Van der Smissen P, Dietz HC, et al. Control of liver cell fate decision by a gradient of TGF beta signaling modulated by onecut transcription factors. Genes Dev 2005;19:1849-1854.
17. Clotman F, Lannoy VJ, Reber M, Cereghini S, Cassiman D, Jacquemin P, et al. The onecut transcription factor HNF6 is required for normal development of the biliary tract. Development 2002;129:1819-1828.
18. Coffinier C, Gresh L, Fiette L, Tronche F, Schutz G, Babinet C, et al. Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta. Development 2002;129:1829-1838.
19. Hussain SZ, Sneddon T, Tan X, Micsenyi A, Michalopoulos GK, Monga SP. Wnt impacts growth and differentiation in ex vivo liver development. Exp Cell Res 2004;292:157-169.
20. Suksaweang S, Lin CM, Jiang TX, Hughes MW, Widelitz RB, Chuong CM. Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation. Dev Biol 2004;266:109-122.
21. Micsenyi A, Tan X, Sneddon T, Luo JH, Michalopoulos GK, Monga SP. Beta-catenin is temporally regulated during normal liver development. Gastroenterology 2004;126:1134-1146.
22. Monga SP, Monga HK, Tan X, Mule K, Pediaditakis P, Michalopoulos GK. Beta-catenin antisense studies in embryonic liver cultures: role in proliferation, apoptosis, and lineage specification. Gastroenterology 2003;124:202-216.
23. Cadoret A, Ovejero C, Saadi-Kheddouci S, Souil E, Fabre M, Romagnolo B, et al. Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin. Cancer Res 2001;61:3245-3249.
24. Harada N, Miyoshi H, Murai N, Oshima H, Tamai Y, Oshima M, et al. Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin. Cancer Res 2002;62:1971-1977.
25. Heiser PW, Lau J, Taketo MM, Herrera PL, Hebrok M. Stabilization of beta-catenin impacts pancreas growth. Development 2006;133:2023-2032.
26. Lee CS, Buttitta L, Fan CM. Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite. Proc Natl Acad Sci U S A 2001;98:11347-11352.
27. Li J, Ning G, Duncan SA. Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev 2000;14:464-474.
28. Parviz F, Matullo C, Garrison WD, Savatski L, Adamson JW, Ning G, et al. Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet 2003;34:292-296.
29. Ader T, Norel R, Levoci L, Rogler LE. Transcriptional profiling implicates TGFbeta/BMP and notch signaling pathways in ductular differentiation of fetal murine hepatoblasts. Mech Dev 2006;123:177-194.
30. Kodama Y, Hijikata M, Kageyama R, Shimotohno K, Chiba T. The role of notch signaling in the development of intrahepatic bile ducts. Gastroenterology 2004;127:1775-1786.
31. McCright B, Lozier J, Gridley T. A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development 2002;129:1075-1082.
32. McLin VA, Rankin SA, Zorn AM. Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas developmenr. Development 2007;134:2207-2217.
33. Plescia C, Rogler C, Rogler L. Genomic expression analysis implicates Wm signaling pathway and extracellular matrix alterations in hepatic specification and differentiation of murine hepatic stem cells. Differentiation 2001;68:254-269.