-
1
-
-
0030960843
-
A population perspective on diagnostic criteria for Parkinson's disease
-
de Rijk MC, Rocca WA, Anderson DW, Melcon MO, Breteler MM, Maraganore DM. A population perspective on diagnostic criteria for Parkinson's disease. Neurology 48(5), 1277-1281 (1997).
-
(1997)
Neurology
, vol.48
, Issue.5
, pp. 1277-1281
-
-
De Rijk, M.C.1
Rocca, W.A.2
Anderson, D.W.3
Melcon, M.O.4
Breteler, M.M.5
Maraganore, D.M.6
-
2
-
-
33646480477
-
Prevalence of Parkinson's disease in metropolitan and rural Queensland: A general practice survey
-
Peters CM, Gartner CE, Silburn PA, Mellick GD. Prevalence of Parkinson's disease in metropolitan and rural Queensland: a general practice survey. J. Clin. Neurosci. 13(3), 343-348 (2006).
-
(2006)
J. Clin. Neurosci.
, vol.13
, Issue.3
, pp. 343-348
-
-
Peters, C.M.1
Gartner, C.E.2
Silburn, P.A.3
Mellick, G.D.4
-
3
-
-
5344237419
-
Incidence of parkinsonism and Parkinson disease in a general population: The Rotterdam study
-
de Lau LM, Giesbergen PC, de Rijk MC, Hofman A, Koudstaal PJ, Breteler MM. Incidence of parkinsonism and Parkinson disease in a general population: the Rotterdam Study. Neurology 63(7), 1240-1244 (2004).
-
(2004)
Neurology
, vol.63
, Issue.7
, pp. 1240-1244
-
-
De Lau, L.M.1
Giesbergen, P.C.2
De Rijk, M.C.3
Hofman, A.4
Koudstaal, P.J.5
Breteler, M.M.6
-
4
-
-
33846572874
-
Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030
-
Dorsey ER, Constantinescu R, Thompson JP et al. Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030. Neurology 68(5), 384-386 (2007).
-
(2007)
Neurology
, vol.68
, Issue.5
, pp. 384-386
-
-
Dorsey, E.R.1
Constantinescu, R.2
Thompson, J.P.3
-
5
-
-
34548819028
-
The economic impact of Parkinson's disease
-
Findley LJ. The economic impact of Parkinson's disease. Parkinsonism Relat. Disord. 13 (Suppl.), S8-S12 (2007).
-
(2007)
Parkinsonism Relat. Disord.
, vol.13
, Issue.SUPPL.
-
-
Findley, L.J.1
-
6
-
-
30444444255
-
Burden of illness in Parkinson's disease
-
Huse DM, Schulman K, Orsini L, Castelli-Haley J, Kennedy S, Lenhart G. Burden of illness in Parkinson's disease. Mov. Disord. 20(11), 1449-1454 (2005).
-
(2005)
Mov. Disord.
, vol.20
, Issue.11
, pp. 1449-1454
-
-
Huse, D.M.1
Schulman, K.2
Orsini, L.3
Castelli-Haley, J.4
Kennedy, S.5
Lenhart, G.6
-
7
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H, Del Tredici K, Rub U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging 24(2), 197-211 (2003).
-
(2003)
Neurobiol. Aging
, vol.24
, Issue.2
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
De Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
9
-
-
0035940582
-
Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease
-
Hughes AJ, Daniel SE, Lees AJ. Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease. Neurology 57(8), 1497-1499 (2001).
-
(2001)
Neurology
, vol.57
, Issue.8
, pp. 1497-1499
-
-
Hughes, A.J.1
Daniel, S.E.2
Lees, A.J.3
-
10
-
-
0032937059
-
Diagnostic criteria for Parkinson disease
-
Gelb DJ, Oliver E, Gilman S. Diagnostic criteria for Parkinson disease. Arch. Neurol. 56(1), 33-39 (1999).
-
(1999)
Arch. Neurol.
, vol.56
, Issue.1
, pp. 33-39
-
-
Gelb, D.J.1
Oliver, E.2
Gilman, S.3
-
11
-
-
0026514953
-
Accuracy of clinical diagnosis of idiopathic Parkinson's disease: A clinico-pathological study of 100 cases [see comments]
-
Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases [see comments]. J. Neurol. Neurosurg. Psychiatry 55(3), 181-184 (1992).
-
(1992)
J. Neurol. Neurosurg. Psychiatry
, vol.55
, Issue.3
, pp. 181-184
-
-
Hughes, A.J.1
Daniel, S.E.2
Kilford, L.3
Lees, A.J.4
-
12
-
-
0036209085
-
The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service
-
Hughes AJ, Daniel SE, Ben-Shlomo Y, Lees AJ. The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service. Brain 125 (Pt 4), 861-870 (2002).
-
(2002)
Brain
, vol.125
, Issue.4 PART
, pp. 861-870
-
-
Hughes, A.J.1
Daniel, S.E.2
Ben-Shlomo, Y.3
Lees, A.J.4
-
13
-
-
0040191763
-
Genomic medicine and the future of health care
-
Sander C. Genomic medicine and the future of health care. Science 287(5460), 1977-1978 (2000).
-
(2000)
Science
, vol.287
, Issue.5460
, pp. 1977-1978
-
-
Sander, C.1
-
14
-
-
0034802767
-
Considerations in the evaluation of surrogate endpoints in clinical trials: Summary of a national institutes of health workshop
-
De Gruttola VG, Clax P, DeMets DL et al. Considerations in the evaluation of surrogate endpoints in clinical trials: summary of a National Institutes of Health Workshop. Control. Clin. Trials 22(5), 485-502 (2001).
-
(2001)
Control. Clin. Trials
, vol.22
, Issue.5
, pp. 485-502
-
-
De Gruttola, V.G.1
Clax, P.2
DeMets, D.L.3
-
15
-
-
0023765129
-
Olfactory dysfunction in parkinsonism: A general deficit unrelated to neurologic signs, disease stage, or disease duration
-
Doty RL, Deems DA, Stellar S. Olfactory dysfunction in parkinsonism: a general deficit unrelated to neurologic signs, disease stage, or disease duration. Neurology 38(8), 1237-1244 (1988).
-
(1988)
Neurology
, vol.38
, Issue.8
, pp. 1237-1244
-
-
Doty, R.L.1
Deems, D.A.2
Stellar, S.3
-
16
-
-
67650753670
-
Prevalence of smell loss in Parkinson's disease - A multicenter study
-
Haehner A, Boesveldt S, Berendse HW et al. Prevalence of smell loss in Parkinson's disease - a multicenter study. Parkinsonism Relat. Disord. 15(7), 490-494 (2009).
-
(2009)
Parkinsonism Relat. Disord.
, vol.15
, Issue.7
, pp. 490-494
-
-
Haehner, A.1
Boesveldt, S.2
Berendse, H.W.3
-
17
-
-
72049090916
-
Olfactory dysfunction as a diagnostic marker for Parkinson's disease
-
Haehner A, Hummel T, Reichmann H. Olfactory dysfunction as a diagnostic marker for Parkinson's disease. Expert Rev. Neurother. 9(12), 1773-1779 (2009).
-
(2009)
Expert Rev. Neurother.
, vol.9
, Issue.12
, pp. 1773-1779
-
-
Haehner, A.1
Hummel, T.2
Reichmann, H.3
-
18
-
-
33746649565
-
Olfaction in neurodegenerative disorder
-
Hawkes C. Olfaction in neurodegenerative disorder. Adv. Otorhinolaryngol. 63, 133-151 (2006).
-
(2006)
Adv. Otorhinolaryngol.
, vol.63
, pp. 133-151
-
-
Hawkes, C.1
-
19
-
-
65549111767
-
Neurochemical approaches in the laboratory diagnosis of Parkinson and Parkinson dementia syndromes: A review
-
Jesse S, Steinacker P, Lehnert S, Gillardon F, Hengerer B, Otto M. Neurochemical approaches in the laboratory diagnosis of Parkinson and Parkinson dementia syndromes: a review. CNS Neurosci. Ther. 15(2), 157-182 (2009).
-
(2009)
CNS Neurosci. Ther.
, vol.15
, Issue.2
, pp. 157-182
-
-
Jesse, S.1
Steinacker, P.2
Lehnert, S.3
Gillardon, F.4
Hengerer, B.5
Otto, M.6
-
20
-
-
33646082990
-
Practice parameter: Diagnosis and prognosis of new onset Parkinson disease (an evidence-based review): Report of the quality standards subcommittee of the American academy of neurology
-
Suchowersky O, Reich S, Perlmutter J, Zesiewicz T, Gronseth G, Weiner WJ. Practice parameter: diagnosis and prognosis of new onset Parkinson disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 66(7), 968-975 (2006).
-
(2006)
Neurology
, vol.66
, Issue.7
, pp. 968-975
-
-
Suchowersky, O.1
Reich, S.2
Perlmutter, J.3
Zesiewicz, T.4
Gronseth, G.5
Weiner, W.J.6
-
21
-
-
61949220753
-
The Parkinson chimera
-
Lees AJ. The Parkinson chimera. Neurology 72 (7 Suppl.), S2-S11 (2009).
-
(2009)
Neurology
, vol.72
, Issue.7 SUPPL.
-
-
Lees, A.J.1
-
22
-
-
70450194705
-
Hereditary parkinsonism: Parkinson disease look-alikes - An algorithm for clinicians to "PARK" genes and beyond
-
Klein C, Schneider SA, Lang AE. Hereditary parkinsonism: Parkinson disease look-alikes - an algorithm for clinicians to "PARK" genes and beyond. Mov. Disord. 24(14), 2042-2058 (2009).
-
(2009)
Mov. Disord.
, vol.24
, Issue.14
, pp. 2042-2058
-
-
Klein, C.1
Schneider, S.A.2
Lang, A.E.3
-
23
-
-
53449100597
-
Neuroimaging and transcranial ultrasonography in Parkinson's disease
-
Mehta SH, Morgan JC, Sethi KD. Neuroimaging and transcranial ultrasonography in Parkinson's disease. Curr. Neurol. Neurosci. Rep. 8(4), 297-303 (2008).
-
(2008)
Curr. Neurol. Neurosci. Rep.
, vol.8
, Issue.4
, pp. 297-303
-
-
Mehta, S.H.1
Morgan, J.C.2
Sethi, K.D.3
-
24
-
-
0033595447
-
Vulnerability of the nigrostriatal system as detected by transcranial ultrasound
-
Berg D, Becker G, Zeiler B et al. Vulnerability of the nigrostriatal system as detected by transcranial ultrasound. Neurology 53(5), 1026-1031 (1999).
-
(1999)
Neurology
, vol.53
, Issue.5
, pp. 1026-1031
-
-
Berg, D.1
Becker, G.2
Zeiler, B.3
-
25
-
-
33644758218
-
Application of transcranial sonography in extrapyramidal disorders: Updated recommendations
-
Berg D, Behnke S, Walter U. Application of transcranial sonography in extrapyramidal disorders: updated recommendations. Ultraschall. Med. 27(1), 12-19 (2006).
-
(2006)
Ultraschall. Med.
, vol.27
, Issue.1
, pp. 12-19
-
-
Berg, D.1
Behnke, S.2
Walter, U.3
-
26
-
-
53649086350
-
Transcranial sonography in movement disorders
-
Berg D, Godau J, Walter U. Transcranial sonography in movement disorders. Lancet Neurol. 7(11), 1044-1055 (2008).
-
(2008)
Lancet Neurol.
, vol.7
, Issue.11
, pp. 1044-1055
-
-
Berg, D.1
Godau, J.2
Walter, U.3
-
27
-
-
0029020537
-
123I]iodobenzylguanidine in neurological patients with autonomic failure
-
123I]iodobenzylguanidine in neurological patients with autonomic failure. J. Auton. Nerv. Syst. 53 (2-3), 230-234 (1995).
-
(1995)
J. Auton. Nerv. Syst.
, vol.53
, Issue.2-3
, pp. 230-234
-
-
Hirayama, M.1
Hakusui, S.2
Koike, Y.3
-
28
-
-
12444250109
-
Reliability of MIBG myocardial scintigraphy in the diagnosis of Parkinson's disease
-
Nagayama H, Hamamoto M, Ueda M, Nagashima J, Katayama Y. Reliability of MIBG myocardial scintigraphy in the diagnosis of Parkinson's disease. J. Neurol. Neurosurg. Psychiatry 76(2), 249-251 (2005).
-
(2005)
J. Neurol. Neurosurg. Psychiatry
, vol.76
, Issue.2
, pp. 249-251
-
-
Nagayama, H.1
Hamamoto, M.2
Ueda, M.3
Nagashima, J.4
Katayama, Y.5
-
29
-
-
34848881084
-
123I-MIBG uptake reflects cardiac sympathetic dysfunction in Lewy body disease
-
123I-MIBG uptake reflects cardiac sympathetic dysfunction in Lewy body disease. Neurology 69(14), 1460-1465 (2007).
-
(2007)
Neurology
, vol.69
, Issue.14
, pp. 1460-1465
-
-
Oka, H.1
Yoshioka, M.2
Morita, M.3
-
30
-
-
72849145695
-
123I-metaiodobenzylguanidine scintigraphy in Parkinson's disease and related disorders
-
123I-metaiodobenzylguanidine scintigraphy in Parkinson's disease and related disorders. Mov. Disord. 24 (Suppl. 2), S732-S741 (2009).
-
(2009)
Mov. Disord.
, vol.24
, Issue.2 SUPPL.
-
-
Rascol, O.1
Schelosky, L.2
-
31
-
-
33746085612
-
Preclinical diagnosis of Parkinson's disease: Are we there yet?
-
Siderowf A, Stern MB. Preclinical diagnosis of Parkinson's disease: are we there yet? Curr. Neurol. Neurosci. Rep. 6(4), 295-301 (2006).
-
(2006)
Curr. Neurol. Neurosci. Rep.
, vol.6
, Issue.4
, pp. 295-301
-
-
Siderowf, A.1
Stern, M.B.2
-
32
-
-
58349108478
-
Premotor Parkinsons disease: Clinical features, detection, and prospects for treatment
-
Siderowf A, Stern MB. Premotor Parkinsons disease: clinical features, detection, and prospects for treatment. Ann. Neurol. 64 (Suppl. 2), S139-S147 (2008).
-
(2008)
Ann. Neurol.
, vol.64
, Issue.2 SUPPL.
-
-
Siderowf, A.1
Stern, M.B.2
-
33
-
-
3843134075
-
The preclinical detection of Parkinsons disease: Ready for prime time?
-
Stern MB. The preclinical detection of Parkinsons disease: ready for prime time? Ann. Neurol. 56(2), 169-171 (2004).
-
(2004)
Ann. Neurol.
, vol.56
, Issue.2
, pp. 169-171
-
-
Stern, M.B.1
-
34
-
-
72849141132
-
Supplement neuroimaging movement disorders
-
• A 'must read' for those interested in the potential of imaging biomarkers for Parkinson's disease PD and the identification of the prodrome of this disorder
-
Poewe W, Scherfler C, Tolosa E, Marek K. Supplement neuroimaging movement disorders. Mov. Disord. 24 (Suppl. 2), S655 (2009). • A 'must read' for those interested in the potential of imaging biomarkers for Parkinson's disease (PD) and the identification of the prodrome of this disorder.
-
(2009)
Mov. Disord.
, vol.24
, Issue.2 SUPPL.
-
-
Poewe, W.1
Scherfler, C.2
Tolosa, E.3
Marek, K.4
-
35
-
-
40749152391
-
Parkinsons disease: A genetic perspective
-
Belin AC, Westerlund M. Parkinsons disease: a genetic perspective. FEBS J. 275(7), 1377-1383 (2008).
-
(2008)
FEBS J.
, vol.275
, Issue.7
, pp. 1377-1383
-
-
Belin, A.C.1
Westerlund, M.2
-
36
-
-
33644919942
-
Implications of genetics on the diagnosis and care of patients with Parkinson disease
-
Klein C. Implications of genetics on the diagnosis and care of patients with Parkinson disease. Arch. Neurol. 63(3), 328-334 (2006).
-
(2006)
Arch. Neurol.
, vol.63
, Issue.3
, pp. 328-334
-
-
Klein, C.1
-
37
-
-
33644610520
-
The genetics of Parkinson disease: Implications for neurological care
-
Klein C, Schlossmacher MG. The genetics of Parkinson disease: implications for neurological care. Nat. Clin. Pract. Neurol. 2(3), 136-146 (2006).
-
(2006)
Nat. Clin. Pract. Neurol.
, vol.2
, Issue.3
, pp. 136-146
-
-
Klein, C.1
Schlossmacher, M.G.2
-
38
-
-
0036699093
-
Diagnostic testing in neurogenetics. Principles, limitations, and ethical considerations
-
Paulson HL. Diagnostic testing in neurogenetics. Principles, limitations, and ethical considerations. Neurol. Clin. 20(3), 627-643, v (2002).
-
(2002)
Neurol. Clin.
, vol.20
, Issue.3
, pp. 627-643
-
-
Paulson, H.L.1
-
39
-
-
24144461276
-
Genetic testing in Parkinsons disease
-
• Presents a very thoughtful discussion of the important considerations involved with genetic testing for PD. Although over 5 years old, the important issues raised remain extremely relevant
-
McInerney-Leo A. Genetic testing in Parkinsons disease. Mov. Disord. 20(7), 908-909 (2005). • Presents a very thoughtful discussion of the important considerations involved with genetic testing for PD. Although over 5 years old, the important issues raised remain extremely relevant.
-
(2005)
Mov. Disord.
, vol.20
, Issue.7
, pp. 908-909
-
-
McInerney-Leo, A.1
-
40
-
-
66749103174
-
EFNS guidelines on the molecular diagnosis of neurogenetic disorders: General issues, Huntington's disease, Parkinson's disease and dystonias
-
Harbo HF, Finsterer J, Baets J et al. EFNS guidelines on the molecular diagnosis of neurogenetic disorders: general issues, Huntington's disease, Parkinson's disease and dystonias. Eur. J. Neurol. 16(7), 777-785 (2009).
-
(2009)
Eur. J. Neurol.
, vol.16
, Issue.7
, pp. 777-785
-
-
Harbo, H.F.1
Finsterer, J.2
Baets, J.3
-
41
-
-
67649535100
-
Chipping away at diagnostics for neurodegenerative diseases
-
Scherzer CR. Chipping away at diagnostics for neurodegenerative diseases. Neurobiol. Dis. 35(2), 148-156 (2009).
-
(2009)
Neurobiol. Dis.
, vol.35
, Issue.2
, pp. 148-156
-
-
Scherzer, C.R.1
-
42
-
-
41249098565
-
RNA biomarkers of Parkinson's disease: Developing tools for novel therapies
-
Hennecke G, Scherzer CR. RNA biomarkers of Parkinson's disease: developing tools for novel therapies. Biomark. Med. 2(1), 41-53 (2008).
-
(2008)
Biomark. Med.
, vol.2
, Issue.1
, pp. 41-53
-
-
Hennecke, G.1
Scherzer, C.R.2
-
43
-
-
22844446947
-
An integrative genomics approach to infer causal associations between gene expression and disease
-
Schadt EE, Lamb J, Yang X et al. An integrative genomics approach to infer causal associations between gene expression and disease. Nat. Genet. 37(7), 710-717 (2005).
-
(2005)
Nat. Genet.
, vol.37
, Issue.7
, pp. 710-717
-
-
Schadt, E.E.1
Lamb, J.2
Yang, X.3
-
44
-
-
58349108690
-
Biomarkers for Parkinson's [corrected] disease: Tools to assess Parkinson's disease onset and progression
-
•• Articulates the important requirements for the discovery of effective biomarkers with an emphasis on PD
-
Marek K, Jennings D, Tamagnan G, Seibyl J. Biomarkers for Parkinson's [corrected] disease: tools to assess Parkinson's disease onset and progression. Ann. Neurol. 64 (Suppl. 2), S111-S121 (2008). •• Articulates the important requirements for the discovery of effective biomarkers with an emphasis on PD.
-
(2008)
Ann. Neurol.
, vol.64
, Issue.2 SUPPL.
-
-
Marek, K.1
Jennings, D.2
Tamagnan, G.3
Seibyl, J.4
-
45
-
-
33344454373
-
The peripheral blood transcriptome dynamically reflects system wide biology: A potential diagnostic tool
-
Liew CC, Ma J, Tang HC, Zheng R, Dempsey AA. The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool. J. Lab. Clin. Med. 147(3), 126-132 (2006).
-
(2006)
J. Lab. Clin. Med.
, vol.147
, Issue.3
, pp. 126-132
-
-
Liew, C.C.1
Ma, J.2
Tang, H.C.3
Zheng, R.4
Dempsey, A.A.5
-
46
-
-
35248840944
-
The peripheral-blood transcriptome: New insights into disease and risk assessment
-
Mohr S, Liew CC. The peripheral-blood transcriptome: new insights into disease and risk assessment. Trends Mol. Med. 13(10), 422-432 (2007).
-
(2007)
Trends Mol. Med.
, vol.13
, Issue.10
, pp. 422-432
-
-
Mohr, S.1
Liew, C.C.2
-
47
-
-
0036041572
-
Determinants of lumbar CSF protein concentration
-
Seyfert S, Kunzmann V, Schwertfeger N, Koch HC, Faulstich A. Determinants of lumbar CSF protein concentration. J. Neurol. 249(8), 1021-1026 (2002).
-
(2002)
J. Neurol.
, vol.249
, Issue.8
, pp. 1021-1026
-
-
Seyfert, S.1
Kunzmann, V.2
Schwertfeger, N.3
Koch, H.C.4
Faulstich, A.5
-
48
-
-
77950223687
-
DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
-
Hong Z, Shi M, Chung KA et al. DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 133 (Pt 3), 713-726 (2010).
-
(2010)
Brain
, vol.133
, Issue.3 PART
, pp. 713-726
-
-
Hong, Z.1
Shi, M.2
Chung, K.A.3
-
49
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner F, Hockemeyer D, Beard C et al. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136(5), 964-977 (2009).
-
(2009)
Cell.
, vol.136
, Issue.5
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
-
50
-
-
78649284827
-
Disease-specific, neurosphere-derived cells as models for brain disorders
-
DOI: 10.1242/dmm.005447, Epub ahead of print
-
Matigian N, Abrahamsen G, Sutharsan R et al. Disease-specific, neurosphere-derived cells as models for brain disorders. Dis. Model. Mech. DOI: 10.1242/dmm.005447 (2010) (Epub ahead of print).
-
(2010)
Dis. Model. Mech.
-
-
Matigian, N.1
Abrahamsen, G.2
Sutharsan, R.3
-
51
-
-
23044526646
-
'Ome sweet 'omics - A genealogical treasury of words
-
Lederberg J, McCray A. 'Ome sweet 'omics - a genealogical treasury of words. The Scientist 15(7), 8(2001).
-
(2001)
The Scientist
, vol.15
, Issue.7
, pp. 8
-
-
Lederberg, J.1
McCray, A.2
-
52
-
-
37349022446
-
Genetics of Parkinson disease
-
Pankratz N, Foroud T. Genetics of Parkinson disease. Genet. Med. 9(12), 801-811 (2007).
-
(2007)
Genet. Med.
, vol.9
, Issue.12
, pp. 801-811
-
-
Pankratz, N.1
Foroud, T.2
-
53
-
-
77954104112
-
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: A mutation update
-
Nuytemans K, Theuns J, Cruts M, Van Broeckhoven C. Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update. Hum. Mutat. 31(7), 763-780 (2010).
-
(2010)
Hum. Mutat
, vol.31
, Issue.7
, pp. 763-780
-
-
Nuytemans, K.1
Theuns, J.2
Cruts, M.3
Van Broeckhoven, C.4
-
54
-
-
69149089036
-
Molecular pathogenesis of Parkinson disease: Insights from genetic studies
-
Gasser T. Molecular pathogenesis of Parkinson disease: insights from genetic studies. Expert Rev. Mol. Med. 11, e22 (2009).
-
(2009)
Expert Rev. Mol. Med.
, vol.11
-
-
Gasser, T.1
-
55
-
-
68649097307
-
The genetics of Parkinson's syndromes: A critical review
-
Hardy J, Lewis P, Revesz T, Lees A, Paisan-Ruiz C. The genetics of Parkinson's syndromes: a critical review. Curr. Opin. Genet. Devel. 19(3), 254-265 (2009).
-
(2009)
Curr. Opin. Genet. Devel
, vol.19
, Issue.3
, pp. 254-265
-
-
Hardy, J.1
Lewis, P.2
Revesz, T.3
Lees, A.4
Paisan-Ruiz, C.5
-
56
-
-
63149090431
-
Parkinson's disease: From monogenic forms to genetic susceptibility factors
-
Lesage S, Brice A. Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum. Mol. Genet. 18 (R1), R48-R59 (2009).
-
(2009)
Hum. Mol. Genet.
, vol.18
, Issue.R1
-
-
Lesage, S.1
Brice, A.2
-
57
-
-
67650073018
-
Variation in GIGYF2 is not associated with Parkinson disease
-
Nichols WC, Kissell DK, Pankratz N et al. Variation in GIGYF2 is not associated with Parkinson disease. Neurology 72(22), 1886-1892 (2009).
-
(2009)
Neurology
, vol.72
, Issue.22
, pp. 1886-1892
-
-
Nichols, W.C.1
Kissell, D.K.2
Pankratz, N.3
-
58
-
-
79952900158
-
A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease
-
DOI: 10.1016/j. neurobiolaging.2009.11.021, Epub ahead of print
-
Kruger R, Sharma M, Riess O et al. A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease. Neurobiol. Aging DOI: 10.1016/j. neurobiolaging.2009.11.021 (2009) (Epub ahead of print).
-
(2009)
Neurobiol. Aging
-
-
Kruger, R.1
Sharma, M.2
Riess, O.3
-
59
-
-
13544253718
-
PARK11 is not linked with Parkinson's disease in European families
-
Prestel J, Sharma M, Leitner P et al. PARK11 is not linked with Parkinson's disease in European families. Eur. J. Hum. Genet. 13(2), 193-197 (2005).
-
(2005)
Eur. J. Hum. Genet.
, vol.13
, Issue.2
, pp. 193-197
-
-
Prestel, J.1
Sharma, M.2
Leitner, P.3
-
60
-
-
2642538585
-
A linkage study of candidate loci in familial Parkinson's disease
-
Wirdefeldt K, Burgess CE, Westerberg L, Payami H, Schalling M. A linkage study of candidate loci in familial Parkinson's disease. BMC Neurol. 3, 6(2003).
-
(2003)
BMC Neurol.
, vol.3
, pp. 6
-
-
Wirdefeldt, K.1
Burgess, C.E.2
Westerberg, L.3
Payami, H.4
Schalling, M.5
-
61
-
-
33749667345
-
Genome-wide genotyping in Parkinson's disease and neurologically normal controls: First stage analysis and public release of data
-
Fung HC, Scholz S, Matarin M et al. Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data. Lancet Neurol. 5(11), 911-916 (2006).
-
(2006)
Lancet Neurol.
, vol.5
, Issue.11
, pp. 911-916
-
-
Fung, H.C.1
Scholz, S.2
Matarin, M.3
-
62
-
-
27244451809
-
High-resolution whole-genome association study of Parkinson disease
-
Maraganore DM, de Andrade M, Lesnick TG et al. High-resolution whole-genome association study of Parkinson disease. Am. J. Hum. Genet. 77(5), 685-693 (2005).
-
(2005)
Am. J. Hum. Genet.
, vol.77
, Issue.5
, pp. 685-693
-
-
Maraganore, D.M.1
De Andrade, M.2
Lesnick, T.G.3
-
63
-
-
33749667971
-
Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: A large-scale international study
-
Elbaz A, Nelson LM, Payami H et al. Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study. Lancet Neurol. 5(11), 917-923 (2006).
-
(2006)
Lancet Neurol.
, vol.5
, Issue.11
, pp. 917-923
-
-
Elbaz, A.1
Nelson, L.M.2
Payami, H.3
-
64
-
-
73949093664
-
Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: Large-scale collaborative study
-
Evangelou E, Maraganore DM, Annesi G et al. Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153 B (1), 220-228 (2009).
-
(2009)
Am. J. Med. Genet. B. Neuropsychiatr. Genet.
, vol.153 B
, Issue.1
, pp. 220-228
-
-
Evangelou, E.1
Maraganore, D.M.2
Annesi, G.3
-
65
-
-
70349771038
-
Genomewide association study for onset age in Parkinson disease
-
Latourelle JC, Pankratz N, Dumitriu A et al. Genomewide association study for onset age in Parkinson disease. BMC Med. Genet. 10, 98(2009).
-
(2009)
BMC Med. Genet.
, vol.10
, pp. 98
-
-
Latourelle, J.C.1
Pankratz, N.2
Dumitriu, A.3
-
66
-
-
58149100151
-
Genomewide association study for susceptibility genes contributing to familial Parkinson disease
-
Pankratz N, Wilk JB, Latourelle JC et al. Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum. Genet. 124(6), 593-605 (2009).
-
(2009)
Hum. Genet.
, vol.124
, Issue.6
, pp. 593-605
-
-
Pankratz, N.1
Wilk, J.B.2
Latourelle, J.C.3
-
67
-
-
70549084415
-
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
-
Satake W, Nakabayashi Y, Mizuta I et al. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat. Genet. 41(12), 1303-1307 (2009).
-
(2009)
Nat. Genet.
, vol.41
, Issue.12
, pp. 1303-1307
-
-
Satake, W.1
Nakabayashi, Y.2
Mizuta, I.3
-
68
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson's disease
-
Simon-Sanchez J, Schulte C, Bras JM et al. Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat. Genet. 41(12), 1308-1312 (2009).
-
(2009)
Nat. Genet.
, vol.41
, Issue.12
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
Schulte, C.2
Bras, J.M.3
-
69
-
-
33645825183
-
Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer
-
Ein-Dor L, Zuk O, Domany E. Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer. Proc. Natl Acad. Sci. USA 103(15), 5923-5928 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, Issue.15
, pp. 5923-5928
-
-
Ein-Dor, L.1
Zuk, O.2
Domany, E.3
-
70
-
-
7444234286
-
Getting the noise out of gene arrays
-
Marshall E. Getting the noise out of gene arrays. Science 306(5696), 630-631 (2004).
-
(2004)
Science
, vol.306
, Issue.5696
, pp. 630-631
-
-
Marshall, E.1
-
71
-
-
13444249852
-
Prediction of cancer outcome with microarrays: A multiple random validation strategy
-
Michiels S, Koscielny S, Hill C. Prediction of cancer outcome with microarrays: a multiple random validation strategy. Lancet 365(9458), 488-492 (2005).
-
(2005)
Lancet
, vol.365
, Issue.9458
, pp. 488-492
-
-
Michiels, S.1
Koscielny, S.2
Hill, C.3
-
72
-
-
40649122979
-
Myocardial nerve fibers are preserved in MPTP-treated mice, despite cardiac sympathetic dysfunction
-
Amino T, Uchihara T, Tsunekawa H et al. Myocardial nerve fibers are preserved in MPTP-treated mice, despite cardiac sympathetic dysfunction. Neurosci. Res. 60(3), 314-318 (2008).
-
(2008)
Neurosci. Res.
, vol.60
, Issue.3
, pp. 314-318
-
-
Amino, T.1
Uchihara, T.2
Tsunekawa, H.3
-
73
-
-
33747409456
-
Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders
-
Abdi F, Quinn JF, Jankovic J et al. Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders. J. Alzheimers Dis. 9(3), 293-348 (2006).
-
(2006)
J. Alzheimers Dis.
, vol.9
, Issue.3
, pp. 293-348
-
-
Abdi, F.1
Quinn, J.F.2
Jankovic, J.3
-
74
-
-
27744603906
-
Alterations of T-lymphocyte populations in Parkinson disease
-
Baba Y, Kuroiwa A, Uitti RJ, Wszolek ZK, Yamada T. Alterations of T-lymphocyte populations in Parkinson disease. Parkinsonism Relat. Disord. 11(8), 493-498 (2005).
-
(2005)
Parkinsonism Relat. Disord.
, vol.11
, Issue.8
, pp. 493-498
-
-
Baba, Y.1
Kuroiwa, A.2
Uitti, R.J.3
Wszolek, Z.K.4
Yamada, T.5
-
75
-
-
63349091122
-
A cross-study transcriptional analysis of Parkinson's disease
-
•• Provides an extensive re-examination of the important trans crip tomic studies in PD and shows that data concordance can be improved when a systematic analytical approach is used. It also shows that pathway analyses reveal superior consistency between studies compared with published gene lists. It also clearly demonstrates how trans crip tomics can mark pathological changes in tissue samples
-
Sutherland GT, Matigian NA, Chalk AM et al. A cross-study transcriptional analysis of Parkinson's disease. PloS ONE 4(3), e4955 (2009). •• Provides an extensive re-examination of the important trans crip tomic studies in PD and shows that data concordance can be improved when a systematic analytical approach is used. It also shows that pathway analyses reveal superior consistency between studies compared with published gene lists. It also clearly demonstrates how trans crip tomics can mark pathological changes in tissue samples.
-
(2009)
PloS ONE
, vol.4
, Issue.3
-
-
Sutherland, G.T.1
Matigian, N.A.2
Chalk, A.M.3
-
76
-
-
49449102642
-
GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein
-
Scherzer CR, Grass JA, Liao Z et al. GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synuclein. Proc. Natl Acad. Sci. USA 105(31), 10907-10912 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.31
, pp. 10907-10912
-
-
Scherzer, C.R.1
Grass, J.A.2
Liao, Z.3
-
77
-
-
34248595527
-
Effects of gender on nigral gene expression and Parkinson disease
-
Cantuti-Castelvetri I, Keller-McGandy C, Bouzou B et al. Effects of gender on nigral gene expression and Parkinson disease. Neurobiol. Dis. 26(3), 606-614 (2007).
-
(2007)
Neurobiol. Dis.
, vol.26
, Issue.3
, pp. 606-614
-
-
Cantuti-Castelvetri, I.1
Keller-McGandy, C.2
Bouzou, B.3
-
78
-
-
67650070391
-
Gene expression profiling of substantia nigra dopamine neurons: Further insights into Parkinson's disease pathology
-
Simunovic F, Yi M, Wang Y et al. Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology. Brain 132 (Pt 7), 1795-1809 (2009).
-
(2009)
Brain
, vol.132
, Issue.7 PART
, pp. 1795-1809
-
-
Simunovic, F.1
Yi, M.2
Wang, Y.3
-
79
-
-
61349162881
-
Filtering strategies for improving protein identification in high-throughput MS/MS studies
-
Salmi J, Nyman TA, Nevalainen OS, Aittokallio T. Filtering strategies for improving protein identification in high-throughput MS/MS studies. Proteomics 9(4), 848-860 (2009).
-
(2009)
Proteomics
, vol.9
, Issue.4
, pp. 848-860
-
-
Salmi, J.1
Nyman, T.A.2
Nevalainen, O.S.3
Aittokallio, T.4
-
80
-
-
61349107243
-
PROTEOMICS Reviews 2009
-
• Readers interested in the advances in proteomics are directed to this issue of Proteomics, which contains review articles covering the latest in technology, bioinformatics and animal proteomics methods
-
Dunn MJ. PROTEOMICS Reviews 2009. Proteomics 9(4), 804-807 (2009). • Readers interested in the advances in proteomics are directed to this issue of Proteomics, which contains review articles covering the latest in technology, bioinformatics and animal proteomics methods.
-
(2009)
Proteomics
, vol.9
, Issue.4
, pp. 804-807
-
-
Dunn, M.J.1
-
81
-
-
10644277894
-
Proteome analysis of human substantia nigra in Parkinson's disease
-
• The only comprehensive human brain proteomic analysis published to date comparing PD and control substantia nigra
-
Basso M, Giraudo S, Corpillo D, Bergamasco B, Lopiano L, Fasano M. Proteome analysis of human substantia nigra in Parkinson's disease. Proteomics 4(12), 3943-3952 (2004). • The only comprehensive human brain proteomic analysis published to date comparing PD and control substantia nigra.
-
(2004)
Proteomics
, vol.4
, Issue.12
, pp. 3943-3952
-
-
Basso, M.1
Giraudo, S.2
Corpillo, D.3
Bergamasco, B.4
Lopiano, L.5
Fasano, M.6
-
82
-
-
39749171899
-
Application of targeted quantitative proteomics analysis in human cerebrospinal fluid using a liquid chromatography matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometer (LC MALDI TOF/TOF) platform
-
Pan S, Rush J, Peskind ER et al. Application of targeted quantitative proteomics analysis in human cerebrospinal fluid using a liquid chromatography matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometer (LC MALDI TOF/TOF) platform. J. Proteome Res. 7(2), 720-730 (2008).
-
(2008)
J. Proteome Res.
, vol.7
, Issue.2
, pp. 720-730
-
-
Pan, S.1
Rush, J.2
Peskind, E.R.3
-
83
-
-
42649111286
-
Proteomic identification of novel proteins associated with Lewy bodies
-
Xia Q, Liao L, Cheng D et al. Proteomic identification of novel proteins associated with Lewy bodies. Front. Biosci. 13, 3850-3856 (2008).
-
(2008)
Front. Biosci.
, vol.13
, pp. 3850-3856
-
-
Xia, Q.1
Liao, L.2
Cheng, D.3
-
84
-
-
77950834717
-
Mitochondrial proteomics as a selective tool for unraveling Parkinson's disease pathogenesis
-
Pienaar IS, Dexter DT, Burkhard PR. Mitochondrial proteomics as a selective tool for unraveling Parkinson's disease pathogenesis. Expert Rev. Proteomics 7(2), 205-226 (2010).
-
(2010)
Expert Rev. Proteomics
, vol.7
, Issue.2
, pp. 205-226
-
-
Pienaar, I.S.1
Dexter, D.T.2
Burkhard, P.R.3
-
85
-
-
42949119345
-
CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases
-
Zhang J, Sokal I, Peskind ER et al. CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases. Am. J. Clin. Pathol. 129(4), 526-529 (2008).
-
(2008)
Am. J. Clin. Pathol.
, vol.129
, Issue.4
, pp. 526-529
-
-
Zhang, J.1
Sokal, I.2
Peskind, E.R.3
-
86
-
-
20944443414
-
Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease
-
discussion 173-180 2005
-
Zhang J, Goodlett DR, Quinn JF et al. Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease. J. Alzheimers Dis. 7(2), 125-133; discussion 173-180 (2005).
-
J. Alzheimers Dis.
, vol.7
, Issue.2
, pp. 125-133
-
-
Zhang, J.1
Goodlett, D.R.2
Quinn, J.F.3
-
87
-
-
57949085678
-
Identification of differentially displayed proteins in cerebrospinal fluid of Parkinson's disease patients: A proteomic approach
-
Sinha A, Srivastava N, Singh S et al. Identification of differentially displayed proteins in cerebrospinal fluid of Parkinson's disease patients: a proteomic approach. Clin. Chim. Acta 400 (1-2), 14-20 (2009).
-
(2009)
Clin. Chim. Acta
, vol.400
, Issue.1-2
, pp. 14-20
-
-
Sinha, A.1
Srivastava, N.2
Singh, S.3
-
88
-
-
70349327368
-
Abnormal serum concentrations of proteins in Parkinson's disease
-
• Important blood proteomic study that identifed 21 candidate proteins contributing to optimal discrimination between PD and control groups
-
Goldknopf IL, Bryson JK, Strelets I et al. Abnormal serum concentrations of proteins in Parkinson's disease. Biochem. Biophys. Res. Commun. 389(2), 321-327 (2009). • Important blood proteomic study that identifed 21 candidate proteins contributing to optimal discrimination between PD and control groups.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.389
, Issue.2
, pp. 321-327
-
-
Goldknopf, I.L.1
Bryson, J.K.2
Strelets, I.3
-
89
-
-
38849159145
-
Metabolomic profiling to develop blood biomarkers for Parkinson's disease
-
•• Blood plasma metabolomic profiling study that shows promise for the identification of discriminators between PD and control subjects. This approach has been followedup in individuals from families carrying PD-related LRR2 mutations 103
-
Bogdanov M, Matson WR, Wang L et al. Metabolomic profiling to develop blood biomarkers for Parkinson's disease. Brain 131 (Pt 2), 389-396 (2008). •• Blood plasma metabolomic profiling study that shows promise for the identification of discriminators between PD and control subjects. This approach has been followedup in individuals from families carrying PD-related LRR2 mutations [103].
-
(2008)
Brain
, vol.131
, Issue.2 PART
, pp. 389-396
-
-
Bogdanov, M.1
Matson, W.R.2
Wang, L.3
-
90
-
-
64249101537
-
Serum inflammatory biomarkers in Parkinson's disease
-
Dufek M, Hamanova M, Lokaj J et al. Serum inflammatory biomarkers in Parkinson's disease. Parkinsonism Relat. Disord. 15(4), 318-320 (2009).
-
(2009)
Parkinsonism Relat. Disord.
, vol.15
, Issue.4
, pp. 318-320
-
-
Dufek, M.1
Hamanova, M.2
Lokaj, J.3
-
91
-
-
45149122797
-
Serum urate as a predictor of clinical and radiographic progression in Parkinson disease
-
Schwarzschild MA, Schwid SR, Marek K et al. Serum urate as a predictor of clinical and radiographic progression in Parkinson disease. Arch. Neurol. 65(6), 716-723 (2008).
-
(2008)
Arch. Neurol.
, vol.65
, Issue.6
, pp. 716-723
-
-
Schwarzschild, M.A.1
Schwid, S.R.2
Marek, K.3
-
92
-
-
34548021226
-
Plasma urate and risk of Parkinson's disease
-
Weisskopf MG, O'Reilly E, Chen H, Schwarzschild MA, Ascherio A. Plasma urate and risk of Parkinson's disease. Am. J. Epidemiol. 166(5), 561-567 (2007).
-
(2007)
Am. J. Epidemiol.
, vol.166
, Issue.5
, pp. 561-567
-
-
Weisskopf, M.G.1
O'Reilly, E.2
Chen, H.3
Schwarzschild, M.A.4
Ascherio, A.5
-
93
-
-
37549057265
-
Peripheral inflammatory biomarkers and risk of Parkinson's disease
-
Chen H, O'Reilly EJ, Schwarzschild MA, Ascherio A. Peripheral inflammatory biomarkers and risk of Parkinson's disease. Am. J. Epidemiol. 167(1), 90-95 (2008).
-
(2008)
Am. J. Epidemiol.
, vol.167
, Issue.1
, pp. 90-95
-
-
Chen, H.1
O'Reilly, E.J.2
Schwarzschild, M.A.3
Ascherio, A.4
-
94
-
-
67349173208
-
Lower serum ceruloplasmin levels correlate with younger age of onset in Parkinson's disease
-
Bharucha KJ, Friedman JK, Vincent AS, Ross ED. Lower serum ceruloplasmin levels correlate with younger age of onset in Parkinson's disease. J. Neurol. 255(12), 1957-1962 (2008).
-
(2008)
J. Neurol.
, vol.255
, Issue.12
, pp. 1957-1962
-
-
Bharucha, K.J.1
Friedman, J.K.2
Vincent, A.S.3
Ross, E.D.4
-
95
-
-
85128457780
-
Proteomics and mass spectrometry for cancer biomarker discovery
-
Lu M, Faull KF, Whitelegge JP et al. Proteomics and mass spectrometry for cancer biomarker discovery. Biomark. Insights 2, 347-360 (2007).
-
(2007)
Biomark. Insights
, vol.2
, pp. 347-360
-
-
Lu, M.1
Faull, K.F.2
Whitelegge, J.P.3
-
96
-
-
0032168794
-
Systematic functional analysis of the yeast genome
-
Oliver SG, Winson MK, Kell DB, Baganz F. Systematic functional analysis of the yeast genome. Trends Biotechnol. 16(9), 373-378 (1998).
-
(1998)
Trends Biotechnol.
, vol.16
, Issue.9
, pp. 373-378
-
-
Oliver, S.G.1
Winson, M.K.2
Kell, D.B.3
Baganz, F.4
-
97
-
-
67049134827
-
Metabolomics tools for identifying biomarkers for neuropsychiatric diseases
-
Quinones MP, Kaddurah-Daouk R. Metabolomics tools for identifying biomarkers for neuropsychiatric diseases. Neurobiol. Dis. 35(2), 165-176 (2009).
-
(2009)
Neurobiol. Dis.
, vol.35
, Issue.2
, pp. 165-176
-
-
Quinones, M.P.1
Kaddurah-Daouk, R.2
-
98
-
-
1942470073
-
Metabolomics by numbers: Acquiring and understanding global metabolite data
-
Goodacre R, Vaidyanathan S, Dunn WB, Harrigan GG, Kell DB. Metabolomics by numbers: acquiring and understanding global metabolite data. Trends Biotechnol 22(5), 245-252 (2004).
-
(2004)
Trends Biotechnol.
, vol.22
, Issue.5
, pp. 245-252
-
-
Goodacre, R.1
Vaidyanathan, S.2
Dunn, W.B.3
Harrigan, G.G.4
Kell, D.B.5
-
100
-
-
57649121825
-
Metabolomics: A global biochemical approach to the study of central nervous system diseases
-
Kaddurah-Daouk R, Krishnan KR. Metabolomics: a global biochemical approach to the study of central nervous system diseases. Neuropsychopharmacology 34(1), 173-186 (2009).
-
(2009)
Neuropsychopharmacology
, vol.34
, Issue.1
, pp. 173-186
-
-
Kaddurah-Daouk, R.1
Krishnan, K.R.2
-
101
-
-
0037086012
-
Attention to relative response across sequential electrodes improves quantitation of coulometric array
-
Shi H, Vigneau-Callahan KE, Matson WR, Kristal BS. Attention to relative response across sequential electrodes improves quantitation of coulometric array. Anal. Biochem. 302(2), 239-245 (2002).
-
(2002)
Anal. Biochem.
, vol.302
, Issue.2
, pp. 239-245
-
-
Shi, H.1
Vigneau-Callahan, K.E.2
Matson, W.R.3
Kristal, B.S.4
-
102
-
-
0035096044
-
Characterization of diet-dependent metabolic serotypes: Analytical and biological variability issues in rats
-
Vigneau-Callahan KE, Shestopalov AI, Milbury PE, Matson WR, Kristal BS. Characterization of diet-dependent metabolic serotypes: analytical and biological variability issues in rats. J. Nutr. 131(3), 924S-932S (2001).
-
(2001)
J. Nutr.
, vol.131
, Issue.3
-
-
Vigneau-Callahan, K.E.1
Shestopalov, A.I.2
Milbury, P.E.3
Matson, W.R.4
Kristal, B.S.5
-
103
-
-
70449552850
-
Metabolomic profiling in LRRK2-related Parkinson's disease
-
Johansen KK, Wang L, Aasly JO et al. Metabolomic profiling in LRRK2-related Parkinson's disease. PloS ONE 4(10), e7551 (2009).
-
(2009)
PloS ONE
, vol.4
, Issue.10
-
-
Johansen, K.K.1
Wang, L.2
Aasly, J.O.3
-
104
-
-
68949110561
-
Metabolic profiling of Parkinson's disease: Evidence of biomarker from gene expression analysis and rapid neural network detection
-
Ahmed SS, Santosh W, Kumar S, Christlet HT. Metabolic profiling of Parkinson's disease: evidence of biomarker from gene expression analysis and rapid neural network detection. J. Biomed. Sci. 16(1), 63(2009).
-
(2009)
J. Biomed. Sci.
, vol.16
, Issue.1
, pp. 63
-
-
Ahmed, S.S.1
Santosh, W.2
Kumar, S.3
Christlet, H.T.4
-
105
-
-
70349487220
-
Serum uric acid levels in patients with Parkinson's disease: Their relationship to treatment and disease duration
-
Andreadou E, Nikolaou C, Gournaras F et al. Serum uric acid levels in patients with Parkinson's disease: their relationship to treatment and disease duration. Clin. Neurol. Neurosurg. 111(9), 724-728 (2009).
-
(2009)
Clin. Neurol. Neurosurg.
, vol.111
, Issue.9
, pp. 724-728
-
-
Andreadou, E.1
Nikolaou, C.2
Gournaras, F.3
-
106
-
-
73549111772
-
Urate as a predictor of the rate of clinical decline in Parkinson disease
-
Ascherio A, LeWitt PA, Xu K et al. Urate as a predictor of the rate of clinical decline in Parkinson disease. Arch. Neurol. 66(12), 1460-1468 (2009).
-
(2009)
Arch. Neurol.
, vol.66
, Issue.12
, pp. 1460-1468
-
-
Ascherio, A.1
LeWitt, P.A.2
Xu, K.3
-
108
-
-
1942438016
-
Rules of evidence for cancer molecular-marker discovery and validation
-
•• A must read for people interested in biomarker discovery. It provides an excellent discussion on rules of evidence and result validation in discovery science
-
Ransohoff DF. Rules of evidence for cancer molecular-marker discovery and validation. Nat. Rev. Cancer 4(4), 309-314 (2004). •• A must read for people interested in biomarker discovery. It provides an excellent discussion on rules of evidence and result validation in discovery science.
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.4
, pp. 309-314
-
-
Ransohoff, D.F.1
-
109
-
-
0038176868
-
Multivariable analysis: A primer for readers of medical research
-
Katz MH. Multivariable analysis: a primer for readers of medical research. Ann. Intern. Med. 138(8), 644-650 (2003).
-
(2003)
Ann. Intern. Med.
, vol.138
, Issue.8
, pp. 644-650
-
-
Katz, M.H.1
-
110
-
-
70350061951
-
Neuroscience in the era of functional genomics and systems biology
-
Geschwind DH, Konopka G. Neuroscience in the era of functional genomics and systems biology. Nature 461(7266), 908-915 (2009).
-
(2009)
Nature
, vol.461
, Issue.7266
, pp. 908-915
-
-
Geschwind, D.H.1
Konopka, G.2
-
111
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
Margulies M, Egholm M, Altman WE et al. Genome sequencing in microfabricated high-density picolitre reactors. Nature 437(7057), 376-380 (2005).
-
(2005)
Nature
, vol.437
, Issue.7057
, pp. 376-380
-
-
Margulies, M.1
Egholm, M.2
Altman, W.E.3
-
112
-
-
24644462173
-
Accurate multiplex polony sequencing of an evolved bacterial genome
-
Shendure J, Porreca GJ, Reppas NB et al. Accurate multiplex polony sequencing of an evolved bacterial genome. Science 309(5741), 1728-1732 (2005).
-
(2005)
Science
, vol.309
, Issue.5741
, pp. 1728-1732
-
-
Shendure, J.1
Porreca, G.J.2
Reppas, N.B.3
-
113
-
-
58149234737
-
Real-time DNA sequencing from single polymerase molecules
-
Eid J, Fehr A, Gray J et al. Real-time DNA sequencing from single polymerase molecules. Science 323(5910), 133-138 (2009).
-
(2009)
Science
, vol.323
, Issue.5910
, pp. 133-138
-
-
Eid, J.1
Fehr, A.2
Gray, J.3
-
114
-
-
77953633735
-
Predictors of parkin mutations in early-onset Parkinson disease: The consortium on risk for early-onset Parkinson disease study
-
Marder KS, Tang MX, Mejia-Santana H et al. Predictors of parkin mutations in early-onset Parkinson disease: the consortium on risk for early-onset Parkinson disease study. Arch. Neurol. 67(6), 731-738 (2010).
-
(2010)
Arch. Neurol.
, vol.67
, Issue.6
, pp. 731-738
-
-
Marder, K.S.1
Tang, M.X.2
Mejia-Santana, H.3
-
115
-
-
58449106639
-
α-synuclein gene rearrangements in dominantly inherited parkinsonism: Frequency, phenotype, and mechanisms
-
Ibanez P, Lesage S, Janin S et al. α-synuclein gene rearrangements in dominantly inherited parkinsonism: frequency, phenotype, and mechanisms. Arch. Neurol. 66(1), 102-108 (2009).
-
(2009)
Arch. Neurol.
, vol.66
, Issue.1
, pp. 102-108
-
-
Ibanez, P.1
Lesage, S.2
Janin, S.3
-
116
-
-
0242300619
-
α-synuclein locus triplication causes Parkinson's disease
-
Singleton AB, Farrer M, Johnson J et al. α-synuclein locus triplication causes Parkinson's disease. Science 302(5646), 841(2003).
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
-
117
-
-
77952711518
-
Allelic imbalance of expression and epigenetic regulation within the α-synuclein wild-type and p. Ala53Thr alleles in Parkinson disease
-
Voutsinas GE, Stavrou EF, Karousos G et al. Allelic imbalance of expression and epigenetic regulation within the α-synuclein wild-type and p. Ala53Thr alleles in Parkinson disease. Hum. Mutat. 31(6), 685-691 (2010).
-
(2010)
Hum. Mutat
, vol.31
, Issue.6
, pp. 685-691
-
-
Voutsinas, G.E.1
Stavrou, E.F.2
Karousos, G.3
-
118
-
-
69449086451
-
DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain
-
Barrachina M, Ferrer I. DNA methylation of Alzheimer disease and tauopathy-related genes in postmortem brain. J. Neuropathol. Exp. Neurol. 68(8), 880-891 (2009).
-
(2009)
J. Neuropathol. Exp. Neurol.
, vol.68
, Issue.8
, pp. 880-891
-
-
Barrachina, M.1
Ferrer, I.2
-
119
-
-
62049086159
-
Biomarkers for Parkinson's disease
-
Graeber MB. Biomarkers for Parkinson's disease. Exp. Neurol. 216(2), 249-253 (2009).
-
(2009)
Exp. Neurol.
, vol.216
, Issue.2
, pp. 249-253
-
-
Graeber, M.B.1
-
120
-
-
36549053104
-
A survey of genetic human cortical gene expression
-
Myers AJ, Gibbs JR, Webster JA et al. A survey of genetic human cortical gene expression. Nat. Genet. 39(12), 1494-1499 (2007).
-
(2007)
Nat. Genet.
, vol.39
, Issue.12
, pp. 1494-1499
-
-
Myers, A.J.1
Gibbs, J.R.2
Webster, J.A.3
-
121
-
-
34447505156
-
DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: Implications for eQTL mapping studies
-
Hovatta I, Zapala MA, Broide RS et al. DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies. Genome Biol. 8(2), R25 (2007).
-
(2007)
Genome Biol.
, vol.8
, Issue.2
-
-
Hovatta, I.1
Zapala, M.A.2
Broide, R.S.3
-
122
-
-
0037444214
-
Genomic convergence: Identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage
-
Hauser MA, Li YJ, Takeuchi S et al. Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage. Hum. Mol. Genet. 12(6), 671-677 (2003).
-
(2003)
Hum. Mol. Genet.
, vol.12
, Issue.6
, pp. 671-677
-
-
Hauser, M.A.1
Li, Y.J.2
Takeuchi, S.3
-
123
-
-
34347338776
-
A genomic pathway approach to a complex disease: Axon guidance and Parkinson disease
-
Lesnick TG, Papapetropoulos S, Mash DC et al. A genomic pathway approach to a complex disease: axon guidance and Parkinson disease. PLoS Genet. 3(6), e98 (2007).
-
(2007)
PLoS Genet.
, vol.3
, Issue.6
-
-
Lesnick, T.G.1
Papapetropoulos, S.2
Mash, D.C.3
-
124
-
-
22544469751
-
Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra
-
Noureddine MA, Li YJ, van der Walt JM et al. Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra. Mov. Disord. 20(10), 1299-1309 (2005).
-
(2005)
Mov. Disord.
, vol.20
, Issue.10
, pp. 1299-1309
-
-
Noureddine, M.A.1
Li, Y.J.2
Van Der Walt, J.M.3
-
125
-
-
61649092571
-
Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10
-
Liang X, Slifer M, Martin ER et al. Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10. Hum. Mutat. 30(3), 463-471 (2009).
-
(2009)
Hum. Mutat
, vol.30
, Issue.3
, pp. 463-471
-
-
Liang, X.1
Slifer, M.2
Martin, E.R.3
-
126
-
-
64149105182
-
Genetic control of human brain transcript expression in Alzheimer disease
-
Webster JA, Gibbs JR, Clarke J et al. Genetic control of human brain transcript expression in Alzheimer disease. Am. J. Hum. Genet. 84(4), 445-458 (2009).
-
(2009)
Am. J. Hum. Genet.
, vol.84
, Issue.4
, pp. 445-458
-
-
Webster, J.A.1
Gibbs, J.R.2
Clarke, J.3
-
127
-
-
73549090994
-
Single-cell expression profiling of dopaminergic neurons combined with association analysis identifes pyridoxal kinase as Parkinson's disease gene
-
Elstner M, Morris CM, Heim K et al. Single-cell expression profiling of dopaminergic neurons combined with association analysis identifes pyridoxal kinase as Parkinson's disease gene. Ann. Neurol. 66(6), 792-798 (2009).
-
(2009)
Ann. Neurol.
, vol.66
, Issue.6
, pp. 792-798
-
-
Elstner, M.1
Morris, C.M.2
Heim, K.3
-
128
-
-
42449149436
-
Striatal proteomic analysis suggests that first L-DOPA dose equates to chronic exposure
-
Scholz B, Svensson M, Alm H et al. Striatal proteomic analysis suggests that first L-DOPA dose equates to chronic exposure. PloS ONE 3(2), e1589 (2008).
-
(2008)
PloS ONE
, vol.3
, Issue.2
-
-
Scholz, B.1
Svensson, M.2
Alm, H.3
-
129
-
-
14744305520
-
Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice - A model of familial Parkinson's disease
-
Poon HF, Frasier M, Shreve N, Calabrese V, Wolozin B, Butterfield DA. Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice - a model of familial Parkinson's disease. Neurobiol. Dis. 18(3), 492-498 (2005).
-
(2005)
Neurobiol. Dis.
, vol.18
, Issue.3
, pp. 492-498
-
-
Poon, H.F.1
Frasier, M.2
Shreve, N.3
Calabrese, V.4
Wolozin, B.5
Butterfield, D.A.6
-
130
-
-
39249083911
-
Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: Implications for Parkinson disease
-
Van Laar VS, Dukes AA, Cascio M, Hastings TG. Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: implications for Parkinson disease. Neurobiol. Dis. 29(3), 477-489 (2008).
-
(2008)
Neurobiol. Dis.
, vol.29
, Issue.3
, pp. 477-489
-
-
Van Laar, V.S.1
Dukes, A.A.2
Cascio, M.3
Hastings, T.G.4
-
131
-
-
76949089289
-
Mitochondrial dysfunction in mouse models of Parkinson's disease revealed by transcriptomics and proteomics
-
Smith DJ. Mitochondrial dysfunction in mouse models of Parkinson's disease revealed by transcriptomics and proteomics. J. Bioenerg. Biomembr. 41(6), 487-491 (2009).
-
(2009)
J. Bioenerg. Biomembr
, vol.41
, Issue.6
, pp. 487-491
-
-
Smith, D.J.1
-
132
-
-
73549101721
-
The effect of electro acupuncture for 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced proteomic changes in the mouse striatum
-
Kim ST, Moon W, Chae Y, Kim YJ, Lee H, Park HJ. The effect of electro acupuncture for 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced proteomic changes in the mouse striatum. J. Physiol. Sci. 60(1), 27-34 (2010).
-
(2010)
J. Physiol. Sci.
, vol.60
, Issue.1
, pp. 27-34
-
-
Kim, S.T.1
Moon, W.2
Chae, Y.3
Kim, Y.J.4
Lee, H.5
Park, H.J.6
-
133
-
-
70449587101
-
Genomic and proteomic study to survey the mechanism of action of the anti-Parkinson's disease drug, rasagiline compared with selegiline, in the rat midbrain
-
Weinreb O, Amit T, Sagi Y, Drigues N, Youdim MB. Genomic and proteomic study to survey the mechanism of action of the anti-Parkinson's disease drug, rasagiline compared with selegiline, in the rat midbrain. J. Neural. Transm. 116(11), 1457-1472 (2009).
-
(2009)
J. Neural. Transm.
, vol.116
, Issue.11
, pp. 1457-1472
-
-
Weinreb, O.1
Amit, T.2
Sagi, Y.3
Drigues, N.4
Youdim, M.B.5
-
134
-
-
41549097831
-
Proteomics of Caenorhabditis elegans over-expressing human α-synuclein analyzed by fluorogenic derivatizationliquid chromatography/tandem mass spectrometry: Identification of actin and several ribosomal proteins as negative markers at early Parkinson's disease stages
-
Ichibangase T, Saimaru H, Takamura N et al. Proteomics of Caenorhabditis elegans over-expressing human α-synuclein analyzed by fluorogenic derivatizationliquid chromatography/tandem mass spectrometry: identification of actin and several ribosomal proteins as negative markers at early Parkinson's disease stages. Biomed. Chromatogr. 22(3), 232-234 (2008).
-
(2008)
Biomed. Chromatogr.
, vol.22
, Issue.3
, pp. 232-234
-
-
Ichibangase, T.1
Saimaru, H.2
Takamura, N.3
-
135
-
-
70349783430
-
Mitochondrial dysfunction and Parkinson's disease genes: Insights from Drosophila
-
Park J, Kim Y, Chung J. Mitochondrial dysfunction and Parkinson's disease genes: insights from Drosophila. Dis. Model. Mech. 2 (7-8), 336-340 (2009).
-
(2009)
Dis. Model. Mech.
, vol.2
, Issue.7-8
, pp. 336-340
-
-
Park, J.1
Kim, Y.2
Chung, J.3
-
136
-
-
0141841634
-
Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease
-
Scherzer CR, Jensen RV, Gullans SR, Feany MB. Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease. Hum. Mol. Genet. 12(19), 2457-2466 (2003).
-
(2003)
Hum. Mol. Genet.
, vol.12
, Issue.19
, pp. 2457-2466
-
-
Scherzer, C.R.1
Jensen, R.V.2
Gullans, S.R.3
Feany, M.B.4
-
137
-
-
77953666105
-
Genetic animal models of Parkinson's disease
-
Dawson TM, Ko HS, Dawson VL. Genetic animal models of Parkinson's disease. Neuron 66(5), 646-661 (2010).
-
(2010)
Neuron
, vol.66
, Issue.5
, pp. 646-661
-
-
Dawson, T.M.1
Ko, H.S.2
Dawson, V.L.3
|