Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

Lancet Neurology

Volumn 5, Issue 11, 2006, Pages 911-916

  Fung, Hon Chung ^a,f,g   Scholz, Sonja ^a   Matarin, Mar ^a   Simón Sánchez, Javier ^a,e   Hernandez, Dena ^a   Britton, Angela ^a   Gibbs, J Raphael ^a   Langefeld, Carl ^b   Stiegert, Matt L ^b   Schymick, Jennifer ^a   Okun, Michael S ^c   Mandel, Ronald J ^c   Fernandez, Hubert H ^c   Foote, Kelly D ^c   Rodríguez, Ramón L ^c   Peckham, Elizabeth ^d   De Vrieze, Fabienne Wavrant ^a   Gwinn Hardy, Katrina ^d   Hardy, John A ^a   Singleton, Andrew ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

^d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^e INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^f CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^g UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DATA ANALYSIS; GENETIC VARIABILITY; GENOME; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PARKINSON DISEASE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; AGED, 80 AND OVER; CHROMOSOME MAPPING; COHORT STUDIES; DATABASES, GENETIC; FEMALE; GENE FREQUENCY; GENOMICS; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 33749667345     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(06)70578-6     Document Type: Article

References (22)

1. Kuopio A., Marttila R., Helenius H., and Rinne U. Changing epidemiology of Parkinson's disease in southwestern Finland. Neurology 52 (1999) 302-308
2. de Rijk M., Breteler M., Graveland G., et al. Prevalence of Parkinson's disease in the elderly: the Rotterdam Study. Neurology 45 (1995) 2143-2146
3. Polymeropoulos M., Lavedan C., Leroy E., et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276 (1997) 2045-2047
4. Kitada T., Asakawa S., Hattori N., et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392 (1998) 605-608
5. Bonifati V., Rizzu P., van Baren M., et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299 (2003) 256-259
6. Valente E., Abou-Sleiman P., Caputo V., et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304 (2004) 1158-1160
7. Paisán-Ruiz C., Jain S., Evans E., et al. Cloning of the gene containing mutations that cause PARK8 linked Parkinson disease. Neuron 44 (2004) 595-600
8. Zimprich A., Biskup S., Leitner P., et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 44 (2004) 601-607
9. Maraganore D., de Andrade M., Elbaz A., et al. Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease. JAMA 296 (2006) 661-670
10. The International HapMap Project. Nature 426 (2003) 789-796
11. A haplotype map of the human genome. Nature 437 (2005) 1299-1320
12. Miller G., Shope T., Lisco H., Stitt D., and Lipman M. Epstein-Barr virus: transformation, cytopathic changes, and viral antigens in squirrel monkey and marmoset leukocytes. Proc Natl Acad Sci USA 69 (1972) 383-387
13. Falush D., Stephens M., and Pritchard J. Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics 164 (2003) 1567-1587
14. Maraganore D., de Andrade M., Lesnick T., et al. High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet 77 (2005) 685-693
15. Clarimon J., Scholz S., Fung H., et al. Conflicting results regarding the semaphorin gene (SEMA5A) and the risk for Parkinson disease. Am J Hum Genet 78 (2006) 1082-1084
16. Farrer M., Haugarvoll K., Ross O., et al. Genomewide association, Parkinson disease, and PARK10. Am J Hum Genet 78 (2006) 1084-1088
17. Goris A., Williams-Gray C., Foltynie T., Compston D., Barker R., and Sawcer S. No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening. Am J Hum Genet 78 (2006) 1088-1090
18. Li Y., Rowland C., Schrodi S., et al. A case-control association study of the 12 single-nucleotide polymorphisms implicated in Parkinson disease by a recent genome scan. Am J Hum Genet 78 (2006) 1090-1092
19. Elbaz A., Nelson L., Payami H., et al. Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study. Lancet Neurol (2006). published online Sept 27. DOI: 10.1016/S1474-4422(06)70579-8
20. Klein R., Zeiss C., Chew E., et al. Complement factor H polymorphism in age-related macular degeneration. Science 308 (2005) 385-389
21. Skol A., Scott L., Abecasis G., and Boehnke M. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet 38 (2006) 209-213
22. Payami H., Zareparsi S., James D., and Nutt J. Familial aggregation of Parkinson disease: a comparative study of early-onset and late-onset disease. Arch Neurol 59 (2002) 848-850