-
1
-
-
33750594065
-
Genetics of Parkinson's disease and parkinsonism
-
Hardy J, Cai H, Cookson MR, Gwinn-Hardy K, Singleton A (2006) Genetics of Parkinson's disease and parkinsonism. Ann Neurol 60: 389-398.
-
(2006)
Ann Neurol
, vol.60
, pp. 389-398
-
-
Hardy, J.1
Cai, H.2
Cookson, M.R.3
Gwinn-Hardy, K.4
Singleton, A.5
-
2
-
-
36448964545
-
Parkinson disease, 10 years after its genetic revolution: Multiple clues to a complex disorder
-
Klein C, Schlossmacher MG (2007) Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder. Neurology 69: 2093-2104.
-
(2007)
Neurology
, vol.69
, pp. 2093-2104
-
-
Klein, C.1
Schlossmacher, M.G.2
-
3
-
-
42549125512
-
Review: Familial Parkinson's disease-genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease
-
Schiesling C, Kieper N, Seidel K, Kruger R (2008) Review: Familial Parkinson's disease-genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease. Neuropathol Appl Neurobiol 34: 255-271.
-
(2008)
Neuropathol Appl Neurobiol
, vol.34
, pp. 255-271
-
-
Schiesling, C.1
Kieper, N.2
Seidel, K.3
Kruger, R.4
-
4
-
-
37349004102
-
Parkinson's disease
-
Thomas B, Beal MF (2007) Parkinson's disease. Hum Mol Genet 16 Spec No. 2: R183-194.
-
(2007)
Hum Mol Genet
, vol.16
, Issue.SPEC 2
-
-
Thomas, B.1
Beal, M.F.2
-
5
-
-
28544446980
-
G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort
-
Bras JM, Guerreiro RJ, Ribeiro MH, Januario C, Morgadinho A, et al. (2005) G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort. Mov Disord 20: 1653-1655.
-
(2005)
Mov Disord
, vol.20
, pp. 1653-1655
-
-
Bras, J.M.1
Guerreiro, R.J.2
Ribeiro, M.H.3
Januario, C.4
Morgadinho, A.5
-
6
-
-
27644455523
-
G2019S LRRK2 mutation in French and North African families with Parkinson's disease
-
Lesage S, Ibanez P, Lohmann E, Pollak P, Tison F, et al. (2005) G2019S LRRK2 mutation in French and North African families with Parkinson's disease. Ann Neurol 58: 784-787.
-
(2005)
Ann Neurol
, vol.58
, pp. 784-787
-
-
Lesage, S.1
Ibanez, P.2
Lohmann, E.3
Pollak, P.4
Tison, F.5
-
7
-
-
31344439221
-
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews
-
Ozelius LJ, Senthil G, Saunders-Pullman R, Ohmann E, Deligtisch A, et al. (2006) LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med 354: 424-425.
-
(2006)
N Engl J Med
, vol.354
, pp. 424-425
-
-
Ozelius, L.J.1
Senthil, G.2
Saunders-Pullman, R.3
Ohmann, E.4
Deligtisch, A.5
-
8
-
-
18244394793
-
Clinical features of LRRK2-associated Parkinson's disease in central Norway
-
Aasly JO, Toft M, Fernandez-Mata I, Kachergus J, Hulihan M, et al. (2005) Clinical features of LRRK2-associated Parkinson's disease in central Norway. Ann Neurol 57: 762-765.
-
(2005)
Ann Neurol
, vol.57
, pp. 762-765
-
-
Aasly, J.O.1
Toft, M.2
Fernandez-Mata, I.3
Kachergus, J.4
Hulihan, M.5
-
9
-
-
0033817173
-
SPECT and PET imaging of the dopaminergic system in Parkinson's disease
-
IV/2-7
-
Brucke T, Djamshidian S, Bencsits G, Pirker W, Asenbaum S, et al. (2000) SPECT and PET imaging of the dopaminergic system in Parkinson's disease. J Neurol 247 Suppl 4: IV/2-7.
-
(2000)
J Neurol
, vol.247
, Issue.SUPPL. 4
-
-
Brucke, T.1
Djamshidian, S.2
Bencsits, G.3
Pirker, W.4
Asenbaum, S.5
-
10
-
-
0036523783
-
Combination of dopamine transporter and D2 receptor SPECT in the diagnostic evaluation of PD, MSA, and PSP
-
Kim YJ, Ichise M, Ballinger JR, Vines D, Erami SS, et al. (2002) Combination of dopamine transporter and D2 receptor SPECT in the diagnostic evaluation of PD, MSA, and PSP. Mov Disord 17: 303-312.
-
(2002)
Mov Disord
, vol.17
, pp. 303-312
-
-
Kim, Y.J.1
Ichise, M.2
Ballinger, J.R.3
Vines, D.4
Erami, S.S.5
-
11
-
-
0026491108
-
Markers of dopamine metabolism in Parkinson's disease. The Parkinson Study Group
-
LeWitt PA, Galloway MP, Matson W, Milbury P, McDermott M, et al. (1992) Markers of dopamine metabolism in Parkinson's disease. The Parkinson Study Group. Neurology 42: 2111-2117.
-
(1992)
Neurology
, vol.42
, pp. 2111-2117
-
-
LeWitt, P.A.1
Galloway, M.P.2
Matson, W.3
Milbury, P.4
McDermott, M.5
-
12
-
-
33645833848
-
Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease
-
El-Agnaf OM, Salem SA, Paleologou KE, Curran MD, Gibson MJ, et al. (2006) Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease. Faseb J 20: 419-425.
-
(2006)
Faseb J
, vol.20
, pp. 419-425
-
-
El-Agnaf, O.M.1
Salem, S.A.2
Paleologou, K.E.3
Curran, M.D.4
Gibson, M.J.5
-
13
-
-
33748325848
-
Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease
-
Tokuda T, Salem SA, Allsop D, Mizuno T, Nakagawa M, et al. (2006) Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease. Biochem Biophys Res Commun 349: 162-166.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 162-166
-
-
Tokuda, T.1
Salem, S.A.2
Allsop, D.3
Mizuno, T.4
Nakagawa, M.5
-
14
-
-
38849159145
-
Metabolomic profiling to develop blood biomarkers for Parkinson's disease
-
Bogdanov M, Matson WR, Wang L, Matson T, Saunders-Pullman R, et al. (2008) Metabolomic profiling to develop blood biomarkers for Parkinson's disease. Brain 131: 389-396.
-
(2008)
Brain
, vol.131
, pp. 389-396
-
-
Bogdanov, M.1
Matson, W.R.2
Wang, L.3
Matson, T.4
Saunders-Pullman, R.5
-
15
-
-
33846465545
-
Molecular markers of early Parkinson's disease based on gene expression in blood
-
Scherzer CR, Eklund AC, Morse LJ, Liao Z, Locascio JJ, et al. (2007) Molecular markers of early Parkinson's disease based on gene expression in blood. Proc Natl Acad Sci U S A 104: 955-960.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 955-960
-
-
Scherzer, C.R.1
Eklund, A.C.2
Morse, L.J.3
Liao, Z.4
Locascio, J.J.5
-
16
-
-
1942470073
-
Metabolomics by numbers: Acquiring and understanding global metabolite data
-
Goodacre R, Vaidyanathan S, Dunn WB, Harrigan GG, Kell DB (2004) Metabolomics by numbers: acquiring and understanding global metabolite data. Trends Biotechnol 22: 245-252.
-
(2004)
Trends Biotechnol
, vol.22
, pp. 245-252
-
-
Goodacre, R.1
Vaidyanathan, S.2
Dunn, W.B.3
Harrigan, G.G.4
Kell, D.B.5
-
17
-
-
0036913503
-
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics
-
Brindle JT, Antti H, Holmes E, Tranter G, Nicholson JK, et al. (2002) Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics. Nat Med 8: 1439-1444.
-
(2002)
Nat Med
, vol.8
, pp. 1439-1444
-
-
Brindle, J.T.1
Antti, H.2
Holmes, E.3
Tranter, G.4
Nicholson, J.K.5
-
18
-
-
33750431077
-
Metabolomics as a functional genomic tool for understanding lipid dysfunction in diabetes, obesity and related disorders
-
Griffin JL, Nicholls AW (2006) Metabolomics as a functional genomic tool for understanding lipid dysfunction in diabetes, obesity and related disorders. Pharmacogenomics 7: 1095-1107.
-
(2006)
Pharmacogenomics
, vol.7
, pp. 1095-1107
-
-
Griffin, J.L.1
Nicholls, A.W.2
-
19
-
-
38749107675
-
New strategies to identify molecular markers predicting chemotherapy activity and toxicity in breast cancer
-
Di Leo A, Claudino W, Colangiuli D, Bessi S, Pestrin M, et al. (2007) New strategies to identify molecular markers predicting chemotherapy activity and toxicity in breast cancer. Ann Oncol 18 Suppl 12: xii8-14.
-
(2007)
Ann Oncol
, vol.18
, Issue.SUPPL. 12
-
-
Di Leo, A.1
Claudino, W.2
Colangiuli, D.3
Bessi, S.4
Pestrin, M.5
-
20
-
-
33748354488
-
Metabolic profiling of CSF: Evidence that early intervention may impact on disease progression and outcome in schizophrenia
-
Holmes E, Tsang TM, Huang JT, Leweke FM, Koethe D, et al. (2006) Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia. PLoS Med 3: e327.
-
(2006)
PLoS Med
, vol.3
-
-
Holmes, E.1
Tsang, T.M.2
Huang, J.T.3
Leweke, F.M.4
Koethe, D.5
-
21
-
-
20344385568
-
Metabolomic analysis and signatures in motor neuron disease
-
Rozen S, Cudkowicz ME, Bogdanov M, Matson WR, Kristal BS, et al. (2005) Metabolomic analysis and signatures in motor neuron disease. Metabolomics 1: 101-108.
-
(2005)
Metabolomics
, vol.1
, pp. 101-108
-
-
Rozen, S.1
Cudkowicz, M.E.2
Bogdanov, M.3
Matson, W.R.4
Kristal, B.S.5
-
22
-
-
33645085291
-
Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles
-
Underwood BR, Broadhurst D, Dunn WB, Ellis DI, Michell AW, et al. (2006) Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles. Brain 129: 877-886.
-
(2006)
Brain
, vol.129
, pp. 877-886
-
-
Underwood, B.R.1
Broadhurst, D.2
Dunn, W.B.3
Ellis, D.I.4
Michell, A.W.5
-
23
-
-
33748946787
-
LRRK2 G2019S mutation and Parkinson's disease: A clinical, neuropsychological and neuropsychiatric study in a large Italian sample
-
Goldwurm S, Zini M, Di Fonzo A, De Gaspari D, Siri C, et al. (2006) LRRK2 G2019S mutation and Parkinson's disease: a clinical, neuropsychological and neuropsychiatric study in a large Italian sample. Parkinsonism Relat Disord 12: 410-419.
-
(2006)
Parkinsonism Relat Disord
, vol.12
, pp. 410-419
-
-
Goldwurm, S.1
Zini, M.2
Di Fonzo, A.3
De Gaspari, D.4
Siri, C.5
-
24
-
-
28544441181
-
Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: Clinical, pathological, olfactory and functional imaging and genetic data
-
Khan NL, Jain S, Lynch JM, Pavese N, Abou-Sleiman P, et al. (2005) Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data. Brain 128: 2786-2796.
-
(2005)
Brain
, vol.128
, pp. 2786-2796
-
-
Khan, N.L.1
Jain, S.2
Lynch, J.M.3
Pavese, N.4
Abou-Sleiman, P.5
-
25
-
-
0032937059
-
Diagnostic criteria for Parkinson disease
-
Gelb DJ, Oliver E, Gilman S (1999) Diagnostic criteria for Parkinson disease. Arch Neurol 56: 33-39.
-
(1999)
Arch Neurol
, vol.56
, pp. 33-39
-
-
Gelb, D.J.1
Oliver, E.2
Gilman, S.3
-
26
-
-
0032190369
-
Simultaneous analysis of the majority of low-molecular-weight, redox-active compounds from mitochondria
-
Kristal BS, Vigneau-Callahan KE, Matson WR (1998) Simultaneous analysis of the majority of low-molecular-weight, redox-active compounds from mitochondria. Anal Biochem 263: 18-25.
-
(1998)
Anal Biochem
, vol.263
, pp. 18-25
-
-
Kristal, B.S.1
Vigneau-Callahan, K.E.2
Matson, W.R.3
-
27
-
-
0037086012
-
Attention to relative response across sequential electrodes improves quantitation of coulometric array
-
Shi H, Vigneau-Callahan KE, Matson WR, Kristal BS (2002) Attention to relative response across sequential electrodes improves quantitation of coulometric array. Anal Biochem 302: 239-245.
-
(2002)
Anal Biochem
, vol.302
, pp. 239-245
-
-
Shi, H.1
Vigneau-Callahan, K.E.2
Matson, W.R.3
Kristal, B.S.4
-
28
-
-
0035096044
-
Characterization of diet-dependent metabolic serotypes: Analytical and biological variability issues in rats
-
Vigneau-Callahan KE, Shestopalov AI, Milbury PE, Matson WR, Kristal BS (2001) Characterization of diet-dependent metabolic serotypes: analytical and biological variability issues in rats. J Nutr 131: 924S-932S.
-
(2001)
J Nutr
, vol.131
-
-
Vigneau-Callahan, K.E.1
Shestopalov, A.I.2
Milbury, P.E.3
Matson, W.R.4
Kristal, B.S.5
-
31
-
-
33846240326
-
Statistical strategies for avoiding false discoveries in metabolomics and related experiments
-
Broadhurst DI, Kell DB (2006) Statistical strategies for avoiding false discoveries in metabolomics and related experiments. Metabolomics 2: 171-196.
-
(2006)
Metabolomics
, vol.2
, pp. 171-196
-
-
Broadhurst, D.I.1
Kell, D.B.2
-
32
-
-
33746909835
-
Assessing the performance of statistical validation tools megavariate metabolomics data
-
Rubingh CM, Bijlsma S, Derks EPPA, Bobeldijk I, Verheij ER, et al. (2006) Assessing the performance of statistical validation tools megavariate metabolomics data. Metabolomics 2: 53-61.
-
(2006)
Metabolomics
, vol.2
, pp. 53-61
-
-
Rubingh, C.M.1
Bijlsma, S.2
Derks, E.P.P.A.3
Bobeldijk, I.4
Verheij, E.R.5
-
33
-
-
38949180527
-
Assessment of PLSDA cross validation
-
Westerhuis JA, Hoefsloot HCJ, Smit S, Vis DJ, Smilde AK, et al. (2008) Assessment of PLSDA cross validation. Metabolomics 4: 81-89.
-
(2008)
Metabolomics
, vol.4
, pp. 81-89
-
-
Westerhuis, J.A.1
Hoefsloot, H.C.J.2
Smit, S.3
Vis, D.J.4
Smilde, A.K.5
-
34
-
-
50049104725
-
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: A case-control study
-
Healy DG, Falchi M, O'Sullivan SS, Bonifati V, Durr A, et al. (2008) Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study. Lancet Neurol 7: 583-590.
-
(2008)
Lancet Neurol
, vol.7
, pp. 583-590
-
-
Healy, D.G.1
Falchi, M.2
O'Sullivan, S.S.3
Bonifati, V.4
Durr, A.5
-
35
-
-
34447547493
-
Low plasma uric acid level in Parkinson's disease
-
Annanmaki T, Muuronen A, Murros K (2007) Low plasma uric acid level in Parkinson's disease. Mov Disord 22: 1133-1137.
-
(2007)
Mov Disord
, vol.22
, pp. 1133-1137
-
-
Annanmaki, T.1
Muuronen, A.2
Murros, K.3
-
37
-
-
73549111772
-
-
Ascherio A, LeWitt PA, Xu K, Eberly S, Watts A, et al. (2009) Urate predicts rate of clinical decline in Parkinson disease. Arch Neurol.
-
Ascherio A, LeWitt PA, Xu K, Eberly S, Watts A, et al. (2009) Urate predicts rate of clinical decline in Parkinson disease. Arch Neurol.
-
-
-
-
38
-
-
41349103415
-
Diet, urate, and Parkinson's disease risk in men
-
Gao X, Chen H, Choi HK, Curhan G, Schwarzschild MA, et al. (2008) Diet, urate, and Parkinson's disease risk in men. Am J Epidemiol 167: 831-838.
-
(2008)
Am J Epidemiol
, vol.167
, pp. 831-838
-
-
Gao, X.1
Chen, H.2
Choi, H.K.3
Curhan, G.4
Schwarzschild, M.A.5
-
39
-
-
45149122797
-
Serum urate as a predictor of clinical and radiographic progression in Parkinson disease
-
Schwarzschild MA, Schwid SR, Marek K, Watts A, Lang AE, et al. (2008) Serum urate as a predictor of clinical and radiographic progression in Parkinson disease. Arch Neurol 65: 716-723.
-
(2008)
Arch Neurol
, vol.65
, pp. 716-723
-
-
Schwarzschild, M.A.1
Schwid, S.R.2
Marek, K.3
Watts, A.4
Lang, A.E.5
|