Simple and highly diastereoselective access to 3,4-substituted tetrahydro-1,8-naphthyridines from Morita-Baylis-Hillman adducts

Tetrahedron Letters

Volumn 51, Issue 38, 2010, Pages 4988-4990

  Rodrigues Jr , Manoel T ^a   Gomes, Juliana C ^a   Smith, Joel ^a   Coelho, Fernando ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1,8 NAPHTHYRIDINE DERIVATIVE;

ARTICLE; BAYLIS HILLMAN REACTION; CHEMICAL REACTION; DRUG ISOLATION; DRUG PURIFICATION; HIGH TEMPERATURE; MICHAEL ADDITION; MICROWAVE RADIATION; MORITA BAYLIS HILLMAN REACTION; PROTON TRANSPORT; SILYLATION; STEREOCHEMISTRY; STEREOISOMERISM; ULTRASOUND;

EID: 78549277465     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.07.069     Document Type: Article

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56. The same sequence was carried out with a deprotect MBH adduct, however a poor stereoselectivity was observed (2:1, anti/syn).