An Efficient Synthesis of an αvβ3 Antagonist

Journal of Organic Chemistry

Volumn 69, Issue 6, 2004, Pages 1959-1966

  Yasuda, Nobuyoshi ^a   Hsiao, Yi ^a   Jensen, Mark S ^a   Rivera, Nelo R ^a   Yang, Chunhua ^a   Wells, Kenneth M ^a,b   Yau, James ^a   Palucki, Michael ^a   Tan, Lushi ^a   Dormer, Peter G ^a   Volante, Ralph P ^a   Hughes, David L ^a   Reider, Paul J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DRUG PRODUCTS; FRIEDEL-CRAFTS REACTION;

CYCLIZATION; REGIOCHEMISTRY;

SYNTHESIS (CHEMICAL);

ALPHA V BETA 3 INTEGRIN ANTAGONIST; BETA ALANINE; BETA3 INTEGRIN; CD51 ANTIGEN; IMIDAZOLE DERIVATIVE; TETRAHYDRONAPHTHYRIDINE DERIVATIVE; TETRALIN DERIVATIVE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; NAPHTHYRIDINE DERIVATIVE; VITRONECTIN RECEPTOR;

ADDITION REACTION; ARTICLE; CYCLIZATION; DRUG DESIGN; FRIEDLANDER REACTION; METHODOLOGY; PROCESS DESIGN; REACTION ANALYSIS; STEREOCHEMISTRY; SYNTHESIS; CATALYSIS; CHEMICAL STRUCTURE; DRUG ANTAGONISM; STEREOISOMERISM;

BETA-ALANINE; CATALYSIS; CYCLIZATION; IMIDAZOLES; INTEGRIN ALPHAVBETA3; MOLECULAR STRUCTURE; NAPHTHYRIDINES; STEREOISOMERISM;

EID: 1642270824     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo030297u     Document Type: Article

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30. Trademark by Mitsubishi Chemical.