Disease-associated mutations in cytoplasmic loops 1 and 2 of cystic fibrosis transmembrane conductance regulator impede processing or opening of the channel

Biochemistry

Volumn 36, Issue 39, 1997, Pages 11966-11974

  Seibert, Fabian S ^a   Jia, Yanlin ^b   Mathews, Ceri J ^b   Hanrahan, John W ^b   Riordan, John R ^c   Loo, Tip W ^a   Clarke, David M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLYLIMIDODIPHOSPHATE; IODIDE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CHANNEL GATING; CHO CELL; CONTROLLED STUDY; CYSTIC FIBROSIS; HUMAN; HUMAN CELL; KIDNEY CELL; NONHUMAN; PATCH CLAMP; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PROCESSING;

ADENYLYL IMIDODIPHOSPHATE; ANIMALS; CHO CELLS; CRICETINAE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOPLASM; HUMANS; IODIDES; ION CHANNEL GATING; ION CHANNELS; MUTATION; PATCH-CLAMP TECHNIQUES; PROTEIN FOLDING;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0030775639     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9712652     Document Type: Article

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