A stilbene that binds selectively to transthyretin in cells and remains dark until it undergoes a chemoselective reaction to create a bright blue fluorescent conjugate

Journal of the American Chemical Society

Volumn 132, Issue 45, 2010, Pages 16043-16051

  Choi, Sungwook ^a   Ong, Derrick Sek Tong ^b   Kelly, Jeffery W ^b  

^a Chungnam National University   (South Korea)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO GROUP; BIOLOGICAL ENVIRONMENTS; CELL-PERMEABLE; CELLULAR IMAGING; CHEMOSELECTIVE REACTIONS; ENVIRONMENT-SENSITIVE; HELA CELL; HUMAN PLASMAS; IN-CELL; LONG-TERM GOALS; PROTEOMES; SECOND GENERATION; SECRETORY PATHWAYS; TRANSTHYRETIN;

STOICHIOMETRY;

FLUORESCENCE;

FLUORESCENT DYE; HYBRID PROTEIN; PREALBUMIN; PROTEOME; STILBENE DERIVATIVE;

ARTICLE; BINDING SITE; CELL LYSATE; CHEMICAL BINDING; CONJUGATION; CONTROLLED STUDY; COVALENT BOND; DARKNESS; FEMALE; FLUORESCENCE; HUMAN; HUMAN CELL; IMAGING; KINETICS; NUTRITIONAL STATUS; PKA; PLASMA; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FOLDING; SIGNAL TRANSDUCTION; STOICHIOMETRY; TEMPERATURE;

FIBROBLASTS; FLUORESCENCE; HELA CELLS; HUMANS; PREALBUMIN; RECOMBINANT PROTEINS; STILBENES;

EID: 78449236942     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja104999v     Document Type: Article

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