Discovering transthyretin amyloid fibril inhibitors by limited screening

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 8, 1998, Pages 1389-1401

  Baures, Paul W ^a   Peterson, Scott A ^a   Kelly, Jeffery W ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Amyloid fibril; Inhibition; Screening; Transthyretin

Indexed keywords

AMYLOID; ANTHRANILIC ACID DERIVATIVE; ANTHRAQUINONE DERIVATIVE; BENZOPHENONE DERIVATIVE; FLAVONE DERIVATIVE; FLUFENAMIC ACID; FLUORENONE DERIVATIVE; PREALBUMIN; PROTEIN INHIBITOR; TRANSTHYRETIN AMYLOID FIBRIL INHIBITOR; UNCLASSIFIED DRUG;

AMYLOID NEUROPATHY; AMYLOIDOSIS; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; DRUG SCREENING; DRUG SYNTHESIS;

AMYLOID; AMYLOID NEUROPATHIES; AMYLOIDOSIS; ANTHRAQUINONES; BENZOPHENONES; DRUG EVALUATION, PRECLINICAL; FLAVONOIDS; FLUFENAMIC ACID; HUMANS; PREALBUMIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031684499     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00130-8     Document Type: Article

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