메뉴 건너뛰기




Volumn 28, Issue 6, 2010, Pages 601-607

Genetic aspects of osteoporosis

(1)  Hosoi, Takayuki a  

a NONE

Author keywords

Bone mineral density; Genetics; Osteoporosis; Single nucleotide polymorphism

Indexed keywords

ALKALINE PHOSPHATASE; CARBOXYLASE; ESTROGEN RECEPTOR ALPHA; GAMMA GLUTAMYL HYDROLASE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; MAJOR HISTOCOMPATIBILITY ANTIGEN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; VITAMIN D RECEPTOR; ZINC FINGER PROTEIN;

EID: 78349312418     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00774-010-0217-9     Document Type: Review
Times cited : (40)

References (60)
  • 1
    • 4043178570 scopus 로고    scopus 로고
    • Undertreatment of osteoporosis in women, based on detection of vertebral compression fractures on chest radiography
    • 10.1016/S1543-5946(04)90016-5 15555487
    • PJ Kroth MD Murray CJ McDonald 2004 Undertreatment of osteoporosis in women, based on detection of vertebral compression fractures on chest radiography Am J Geriatr Pharmacother 2 112 118 10.1016/S1543-5946(04)90016-5 15555487
    • (2004) Am J Geriatr Pharmacother , vol.2 , pp. 112-118
    • Kroth, P.J.1    Murray, M.D.2    McDonald, C.J.3
  • 2
    • 0027222768 scopus 로고
    • Consensus Development Conference V, 1993. Diagnosis, prophylaxis and treatment of osteoporosis
    • Consensus Development Center
    • Consensus Development Center (1993) Consensus Development Conference V, 1993. Diagnosis, prophylaxis and treatment of osteoporosis. Am J Med 94:646-650
    • (1993) Am J Med , vol.94 , pp. 646-650
  • 3
    • 0000664911 scopus 로고    scopus 로고
    • NIH consensus development panel on osteoporosis prevention, diagnosis, and therapy
    • NIH Consensus Development Panel
    • NIH Consensus Development Panel (2001) NIH consensus development panel on osteoporosis prevention, diagnosis, and therapy. JAMA 285:785-793
    • (2001) JAMA , vol.285 , pp. 785-793
  • 4
    • 0035991256 scopus 로고    scopus 로고
    • International variation in hip fracture probabilities: Implication for risk assessment
    • 10.1359/jbmr.2002.17.7.1237 12096837
    • JA Kanis O Johnell C De Laet B Jonsson A Oden AK Ogelsby 2002 International variation in hip fracture probabilities: implication for risk assessment J Bone Miner Res 17 1237 1244 10.1359/jbmr.2002.17.7.1237 12096837
    • (2002) J Bone Miner Res , vol.17 , pp. 1237-1244
    • Kanis, J.A.1    Johnell, O.2    De Laet, C.3    Jonsson, B.4    Oden, A.5    Ogelsby, A.K.6
  • 6
    • 21644444684 scopus 로고    scopus 로고
    • Risk of wrist fracture in women is heritable and is influenced by genes that are largely independent of those influencing BMD
    • 10.1359/JBMR.041015 15619671
    • T Andrew L Antioniades KJ Scurrah AJ Macgregor TD Spector 2005 Risk of wrist fracture in women is heritable and is influenced by genes that are largely independent of those influencing BMD J Bone Miner Res 20 67 74 10.1359/JBMR.041015 15619671
    • (2005) J Bone Miner Res , vol.20 , pp. 67-74
    • Andrew, T.1    Antioniades, L.2    Scurrah, K.J.3    MacGregor, A.J.4    Spector, T.D.5
  • 7
    • 33644541419 scopus 로고    scopus 로고
    • Genome-wide scan identified QTLs underlying femoral neck cross-sectional geometry that are novel studied risk factors of osteoporosis
    • 10.1359/JBMR.051202 16491291
    • DH Xiong H Shen P Xiao YF Gua JR Long LJ Zhao YZ Liu HY Deng JL Li RR Recker HW Deng 2006 Genome-wide scan identified QTLs underlying femoral neck cross-sectional geometry that are novel studied risk factors of osteoporosis J Bone Miner Res 21 424 437 10.1359/JBMR.051202 16491291
    • (2006) J Bone Miner Res , vol.21 , pp. 424-437
    • Xiong, D.H.1    Shen, H.2    Xiao, P.3    Gua, Y.F.4    Long, J.R.5    Zhao, L.J.6    Liu, Y.Z.7    Deng, H.Y.8    Li, J.L.9    Recker, R.R.10    Deng, H.W.11
  • 8
    • 33745612144 scopus 로고    scopus 로고
    • Molecular genetics of gene identification for osteoporosis: A 2004 update
    • 10.1359/jbmr.051002 16995806
    • YJ Liu H Shen P Xiao DH Xiong LH Li RR Recker HW Deng 2006 Molecular genetics of gene identification for osteoporosis: a 2004 update J Bone Miner Res 21 1511 1535 10.1359/jbmr.051002 16995806
    • (2006) J Bone Miner Res , vol.21 , pp. 1511-1535
    • Liu, Y.J.1    Shen, H.2    Xiao, P.3    Xiong, D.H.4    Li, L.H.5    Recker, R.R.6    Deng, H.W.7
  • 9
    • 0029559139 scopus 로고
    • Association of estrogen receptor dinucleotide repeat polymorphism with osteoporosis
    • 10.1006/bbrc.1995.2787 8526937
    • M Sano S Inoue T Hosoi Y Ouchi M Emi M Shiraki H Orimo 1995 Association of estrogen receptor dinucleotide repeat polymorphism with osteoporosis Biochem Biophys Res Commun 217 378 383 10.1006/bbrc.1995.2787 8526937
    • (1995) Biochem Biophys Res Commun , vol.217 , pp. 378-383
    • Sano, M.1    Inoue, S.2    Hosoi, T.3    Ouchi, Y.4    Emi, M.5    Shiraki, M.6    Orimo, H.7
  • 10
    • 0030003796 scopus 로고    scopus 로고
    • Association of bone mineral density with polymorphism of the estrogen receptor gene
    • 10.1002/jbmr.5650110304 8852941
    • S Kobayashi S Inoue T Hosoi Y Ouchi M Shiraki H Orimo 1996 Association of bone mineral density with polymorphism of the estrogen receptor gene J Bone Miner Res 11 306 311 10.1002/jbmr.5650110304 8852941
    • (1996) J Bone Miner Res , vol.11 , pp. 306-311
    • Kobayashi, S.1    Inoue, S.2    Hosoi, T.3    Ouchi, Y.4    Shiraki, M.5    Orimo, H.6
  • 11
    • 0030846737 scopus 로고    scopus 로고
    • Association of bone mineral density with apolipoprotein e phenotype
    • 10.1359/jbmr.1997.12.9.1438
    • M Shiraki Y Shiraki C Aoki T Hosoi S Inoue M Kaneki Y Ouchi 1997 Association of bone mineral density with apolipoprotein E phenotype J Bone Miner Res 1 1438 1445 10.1359/jbmr.1997.12.9.1438
    • (1997) J Bone Miner Res , vol.1 , pp. 1438-1445
    • Shiraki, M.1    Shiraki, Y.2    Aoki, C.3    Hosoi, T.4    Inoue, S.5    Kaneki, M.6    Ouchi, Y.7
  • 13
    • 0032972859 scopus 로고    scopus 로고
    • Association study of parathyroid hormone gene polymorphism and bone mineral density in Japanese postmenopausal women
    • 10.1007/s002239900603 10024376
    • T Hosoi M Miyao S Inoue S Hoshino M Shiraki H Orimo Y Ouchi 1999 Association study of parathyroid hormone gene polymorphism and bone mineral density in Japanese postmenopausal women Calcif Tissue Int 64 205 208 10.1007/s002239900603 10024376
    • (1999) Calcif Tissue Int , vol.64 , pp. 205-208
    • Hosoi, T.1    Miyao, M.2    Inoue, S.3    Hoshino, S.4    Shiraki, M.5    Orimo, H.6    Ouchi, Y.7
  • 14
    • 0031687612 scopus 로고    scopus 로고
    • Polymorphism of insulin-like growth factor i gene and bone mineral density
    • 10.1007/s002239900532 9744989
    • M Miyao T Hosoi S Inoue S Hoshino M Shiraki H Orimo Y Ouchi 1998 Polymorphism of insulin-like growth factor I gene and bone mineral density Calcif Tissue Int 63 306 311 10.1007/s002239900532 9744989
    • (1998) Calcif Tissue Int , vol.63 , pp. 306-311
    • Miyao, M.1    Hosoi, T.2    Inoue, S.3    Hoshino, S.4    Shiraki, M.5    Orimo, H.6    Ouchi, Y.7
  • 15
    • 0032872641 scopus 로고    scopus 로고
    • Linkage of interleukin 6 locus to human osteopenia by sibling pair analysis
    • 10.1007/s004390051097 10987653
    • N Ota SC Hunt T Nakajima T Suzuki T Hosoi H Orimo Y Shirai M Emi 1999 Linkage of interleukin 6 locus to human osteopenia by sibling pair analysis Hum Genet 105 253 257 10.1007/s004390051097 10987653
    • (1999) Hum Genet , vol.105 , pp. 253-257
    • Ota, N.1    Hunt, S.C.2    Nakajima, T.3    Suzuki, T.4    Hosoi, T.5    Orimo, H.6    Shirai, Y.7    Emi, M.8
  • 16
    • 0033600165 scopus 로고    scopus 로고
    • Association of bone mineral density with a polymorphism of the peroxisome proliferator-activated receptor gamma gene: PPAR gamma expression in osteoblasts
    • 10.1006/bbrc.1999.0896 10381354
    • S Ogawa T Urano T Hosoi M Miyao S Hoshino M Fujita M Shiraki H Orimo Y Ouschi S Inoue 1999 Association of bone mineral density with a polymorphism of the peroxisome proliferator-activated receptor gamma gene: PPAR gamma expression in osteoblasts Biochem Biophys Res Commun 260 122 126 10.1006/bbrc.1999.0896 10381354
    • (1999) Biochem Biophys Res Commun , vol.260 , pp. 122-126
    • Ogawa, S.1    Urano, T.2    Hosoi, T.3    Miyao, M.4    Hoshino, S.5    Fujita, M.6    Shiraki, M.7    Orimo, H.8    Ouschi, Y.9    Inoue, S.10
  • 17
    • 0032741708 scopus 로고    scopus 로고
    • Ethnic difference in contribution of Sp1 site variation of COL1A1 gene in genetic predisposition to osteoporosis
    • 10.1007/s002239900711 10541758
    • T Nakajima N Ota Y Shirai A Hata H Yoshida T Suzuki T Hosoi H Orimo M Emi 1999 Ethnic difference in contribution of Sp1 site variation of COL1A1 gene in genetic predisposition to osteoporosis Calcif Tissue Int 65 352 353 10.1007/s002239900711 10541758
    • (1999) Calcif Tissue Int , vol.65 , pp. 352-353
    • Nakajima, T.1    Ota, N.2    Shirai, Y.3    Hata, A.4    Yoshida, H.5    Suzuki, T.6    Hosoi, T.7    Orimo, H.8    Emi, M.9
  • 18
    • 0033949961 scopus 로고    scopus 로고
    • Association of bone mineral density with polymorphism of the human matrix Gla protein locus in elderly women
    • 10.1007/s007740050006 10633274
    • K Tsukamoto H Orimo T Hosoi M Miyao G Yoshida S Watanabe T Suzuki M Emi 2000 Association of bone mineral density with polymorphism of the human matrix Gla protein locus in elderly women J Bone Miner Metab 18 27 30 10.1007/s007740050006 10633274
    • (2000) J Bone Miner Metab , vol.18 , pp. 27-30
    • Tsukamoto, K.1    Orimo, H.2    Hosoi, T.3    Miyao, M.4    Yoshida, G.5    Watanabe, S.6    Suzuki, T.7    Emi, M.8
  • 21
    • 0034052846 scopus 로고    scopus 로고
    • Association of transforming growth factor beta1 genotype with therapeutic response to active vitamin D for postmenopausal osteoporosis
    • 10.1359/jbmr.2000.15.3.415 10750555
    • Y Yamada A Harada T Hosoi A Miyauchi K Ikeda H Ohta M Shiraki 2000 Association of transforming growth factor beta1 genotype with therapeutic response to active vitamin D for postmenopausal osteoporosis J Bone Miner Res 15 415 420 10.1359/jbmr.2000.15.3.415 10750555
    • (2000) J Bone Miner Res , vol.15 , pp. 415-420
    • Yamada, Y.1    Harada, A.2    Hosoi, T.3    Miyauchi, A.4    Ikeda, K.5    Ohta, H.6    Shiraki, M.7
  • 23
    • 0033953774 scopus 로고    scopus 로고
    • Association of methylenetetrahydrofolate reductase (MTHFR) polymorphism with bone mineral density in postmenopausal Japanese women
    • 10.1007/s002230010038 10666493
    • M Miyao H Morita T Hosoi H Kurihara S Inoue S Hoshino M Shiraki Y Yazaki Y Ouchi 2000 Association of methylenetetrahydrofolate reductase (MTHFR) polymorphism with bone mineral density in postmenopausal Japanese women Calcif Tissue Int 66 190 194 10.1007/s002230010038 10666493
    • (2000) Calcif Tissue Int , vol.66 , pp. 190-194
    • Miyao, M.1    Morita, H.2    Hosoi, T.3    Kurihara, H.4    Inoue, S.5    Hoshino, S.6    Shiraki, M.7    Yazaki, Y.8    Ouchi, Y.9
  • 24
    • 0033636514 scopus 로고    scopus 로고
    • Association of bone mineral density with a dinucleotide repeat polymorphism at the calcitonin (CT) locus
    • 10.1007/s100380070006 11185743
    • M Miyao T Hosoi M Emi T Nakajima S Inoue S Hoshino M Shiraki H Orimo Y Ouchi 2000 Association of bone mineral density with a dinucleotide repeat polymorphism at the calcitonin (CT) locus J Hum Genet 45 346 350 10.1007/s100380070006 11185743
    • (2000) J Hum Genet , vol.45 , pp. 346-350
    • Miyao, M.1    Hosoi, T.2    Emi, M.3    Nakajima, T.4    Inoue, S.5    Hoshino, S.6    Shiraki, M.7    Orimo, H.8    Ouchi, Y.9
  • 25
    • 0034576287 scopus 로고    scopus 로고
    • Linkage of human tumor necrosis factor-alpha to human osteoporosis by sib pair analysis
    • 10.1038/sj.gene.6363668 11196702
    • N Ota SC Hunt T Nakajima T Suzuki T Hosoi H Orimo Y Shirai M Emi 2000 Linkage of human tumor necrosis factor-alpha to human osteoporosis by sib pair analysis Genes Immun 1 260 264 10.1038/sj.gene.6363668 11196702
    • (2000) Genes Immun , vol.1 , pp. 260-264
    • Ota, N.1    Hunt, S.C.2    Nakajima, T.3    Suzuki, T.4    Hosoi, T.5    Orimo, H.6    Shirai, Y.7    Emi, M.8
  • 26
    • 0035043560 scopus 로고    scopus 로고
    • A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density
    • 10.1007/s100380170077 11355017
    • N Ota T Nakajima I Nakazawa T Suzuki T Hosoi H Orimo S Inoue Y Shirai M Emi 2001 A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density J Hum Genet 46 267 272 10.1007/s100380170077 11355017
    • (2001) J Hum Genet , vol.46 , pp. 267-272
    • Ota, N.1    Nakajima, T.2    Nakazawa, I.3    Suzuki, T.4    Hosoi, T.5    Orimo, H.6    Inoue, S.7    Shirai, Y.8    Emi, M.9
  • 27
    • 0034859090 scopus 로고    scopus 로고
    • A polymorphic variant at the Werner helicase (WRN) gene is associated with bone density, but not spondylosis, in postmenopausal women
    • 10.1007/s007740170013 11498731
    • N Ogata M Shiraki T Hosoi Y Koshizuka K Nakamura H Kawaguchi 2001 A polymorphic variant at the Werner helicase (WRN) gene is associated with bone density, but not spondylosis, in postmenopausal women J Bone Miner Metab 19 296 301 10.1007/s007740170013 11498731
    • (2001) J Bone Miner Metab , vol.19 , pp. 296-301
    • Ogata, N.1    Shiraki, M.2    Hosoi, T.3    Koshizuka, Y.4    Nakamura, K.5    Kawaguchi, H.6
  • 31
    • 18644370400 scopus 로고    scopus 로고
    • Association of a single nucleotide variant in the human tumor necrosis factor-alpha promoter region with decreased bone mineral density
    • 10.1080/03014460210135730 12396374
    • N Ota T Nakajima Y Ezura H Iwasaki T Suzuki T Hosoi H Orimo S Inoue H Ito M Emi 2002 Association of a single nucleotide variant in the human tumor necrosis factor-alpha promoter region with decreased bone mineral density Ann Hum Biol 29 550 558 10.1080/03014460210135730 12396374
    • (2002) Ann Hum Biol , vol.29 , pp. 550-558
    • Ota, N.1    Nakajima, T.2    Ezura, Y.3    Iwasaki, H.4    Suzuki, T.5    Hosoi, T.6    Orimo, H.7    Inoue, S.8    Ito, H.9    Emi, M.10
  • 32
    • 10744221715 scopus 로고    scopus 로고
    • Association of molecular variants, haplotypes, and linkage disequilibrium within the human vitamin D-binding protein (DBP) gene with postmenopausal bone mineral density
    • 10.1359/jbmr.2003.18.9.1642 12968673
    • Y Ezura T Nakajima M Kajita R Ishida S Inoue H Yoshida T Suzuki M Shiraki T Hosoi H Orimo M Emi 2003 Association of molecular variants, haplotypes, and linkage disequilibrium within the human vitamin D-binding protein (DBP) gene with postmenopausal bone mineral density J Bone Miner Res 18 1642 1649 10.1359/jbmr.2003.18.9.1642 12968673
    • (2003) J Bone Miner Res , vol.18 , pp. 1642-1649
    • Ezura, Y.1    Nakajima, T.2    Kajita, M.3    Ishida, R.4    Inoue, S.5    Yoshida, H.6    Suzuki, T.7    Shiraki, M.8    Hosoi, T.9    Orimo, H.10    Emi, M.11
  • 34
    • 0041971243 scopus 로고    scopus 로고
    • Association of genetic variation of the RIL gene, encoding a PDZ-LIM domain protein and localized in 5q31.1, with low bone mineral density in adult Japanese women
    • 10.1007/s10038-003-0035-1 12908099
    • F Omasu Y Ezura M Kajita R Ishida M Kodaira H Yoshida T Suzuki T Hosoi S Inoue M Shiraki H Orimo M Emi 2003 Association of genetic variation of the RIL gene, encoding a PDZ-LIM domain protein and localized in 5q31.1, with low bone mineral density in adult Japanese women J Hum Genet 48 342 345 10.1007/s10038-003-0035-1 12908099
    • (2003) J Hum Genet , vol.48 , pp. 342-345
    • Omasu, F.1    Ezura, Y.2    Kajita, M.3    Ishida, R.4    Kodaira, M.5    Yoshida, H.6    Suzuki, T.7    Hosoi, T.8    Inoue, S.9    Shiraki, M.10    Orimo, H.11    Emi, M.12
  • 35
    • 16644383500 scopus 로고    scopus 로고
    • Association of multiple nucleotide variations in the pituitary glutaminyl cyclase gene (QPCT) with low radial BMD in adult women
    • 10.1359/JBMR.040324 15231017
    • Y Ezura M Kajita R Ishida S Yoshida H Yoshida T Suzuki T Hosoi S Inoue M Shiraki H Orimo M Emi 2004 Association of multiple nucleotide variations in the pituitary glutaminyl cyclase gene (QPCT) with low radial BMD in adult women J Bone Miner Res 19 1296 1301 10.1359/JBMR.040324 15231017
    • (2004) J Bone Miner Res , vol.19 , pp. 1296-1301
    • Ezura, Y.1    Kajita, M.2    Ishida, R.3    Yoshida, S.4    Yoshida, H.5    Suzuki, T.6    Hosoi, T.7    Inoue, S.8    Shiraki, M.9    Orimo, H.10    Emi, M.11
  • 36
    • 10744221121 scopus 로고    scopus 로고
    • Association of a promoter haplotype (-1542G/-525C) in the tumor necrosis factor receptor associated factor-interacting protein gene with low bone mineral density in Japanese women
    • R Ishida Y Ezura M Emi M Kajita H Yoshida T Suzuki T Hosoi S Inoue M Shiraki H Ito H Orimo 2003 Association of a promoter haplotype (-1542G/-525C) in the tumor necrosis factor receptor associated factor-interacting protein gene with low bone mineral density in Japanese women Bone (NY) 33 237 241
    • (2003) Bone (NY) , vol.33 , pp. 237-241
    • Ishida, R.1    Ezura, Y.2    Emi, M.3    Kajita, M.4    Yoshida, H.5    Suzuki, T.6    Hosoi, T.7    Inoue, S.8    Shiraki, M.9    Ito, H.10    Orimo, H.11
  • 37
    • 18044388164 scopus 로고    scopus 로고
    • Association of a single nucleotide polymorphism in the lipoxygenase ALOX15 5'-flanking region (-5229G/A) with bone mineral density
    • 10.1007/s00774-004-0588-x 15838625
    • T Urano M Shiraki M Fujita T Hosoi H Orimo Y Ouchi S Inoue 2005 Association of a single nucleotide polymorphism in the lipoxygenase ALOX15 5'-flanking region (-5229G/A) with bone mineral density J Bone Miner Metab 23 226 230 10.1007/s00774-004-0588-x 15838625
    • (2005) J Bone Miner Metab , vol.23 , pp. 226-230
    • Urano, T.1    Shiraki, M.2    Fujita, M.3    Hosoi, T.4    Orimo, H.5    Ouchi, Y.6    Inoue, S.7
  • 38
    • 21544472897 scopus 로고    scopus 로고
    • Association of single nucleotide polymorphisms in the promoter region of the pro-opiomelanocortin gene (POMC) with low bone mineral density in adult women
    • 10.1007/s10038-005-0244-x 15864412
    • Y Sudo Y Ezura M Kajita H Yoshida T Suzuki T Hosoi S Inoue M Shirak H Ito M Emi 2005 Association of single nucleotide polymorphisms in the promoter region of the pro-opiomelanocortin gene (POMC) with low bone mineral density in adult women J Hum Genet 50 235 240 10.1007/s10038-005-0244-x 15864412
    • (2005) J Hum Genet , vol.50 , pp. 235-240
    • Sudo, Y.1    Ezura, Y.2    Kajita, M.3    Yoshida, H.4    Suzuki, T.5    Hosoi, T.6    Inoue, S.7    Shirak, M.8    Ito, H.9    Emi, M.10
  • 39
    • 48549104140 scopus 로고    scopus 로고
    • Association of genetic variations of genes encoding thrombospondin, type 1, domain-containing 4 and 7A with low bone mineral density in Japanese women with osteoporosis
    • 10.1007/s10038-008-0300-4 18488137
    • S Mori I Kou H Sato M Emi H Ito T Hosoi S Ikegawa 2008 Association of genetic variations of genes encoding thrombospondin, type 1, domain-containing 4 and 7A with low bone mineral density in Japanese women with osteoporosis J Hum Genet 53 694 697 10.1007/s10038-008-0300-4 18488137
    • (2008) J Hum Genet , vol.53 , pp. 694-697
    • Mori, S.1    Kou, I.2    Sato, H.3    Emi, M.4    Ito, H.5    Hosoi, T.6    Ikegawa, S.7
  • 40
    • 60849122811 scopus 로고    scopus 로고
    • Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese females with osteoporosis
    • 10.1007/s00774-008-0031-9 19172221
    • S Mori I Kou H Sato M Emi H Ito T Hosoi S Ikegawa 2009 Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese females with osteoporosis J Bone Miner Metab 27 213 216 10.1007/s00774-008-0031-9 19172221
    • (2009) J Bone Miner Metab , vol.27 , pp. 213-216
    • Mori, S.1    Kou, I.2    Sato, H.3    Emi, M.4    Ito, H.5    Hosoi, T.6    Ikegawa, S.7
  • 41
    • 14344259508 scopus 로고    scopus 로고
    • Non-replication in genetic studies of complex diseases: Lessons learned from studies of osteoporosis and tentative remedies
    • 10.1359/JBMR.041129 15746981
    • H Shen YJ Liu PY Liu RR Recker HW Deng 2005 Non-replication in genetic studies of complex diseases: lessons learned from studies of osteoporosis and tentative remedies J Bone Miner Res 20 365 376 10.1359/JBMR.041129 15746981
    • (2005) J Bone Miner Res , vol.20 , pp. 365-376
    • Shen, H.1    Liu, Y.J.2    Liu, P.Y.3    Recker, R.R.4    Deng, H.W.5
  • 42
    • 0037442235 scopus 로고    scopus 로고
    • Genetic association in large versus small studies: An empirical assessment
    • 10.1016/S0140-6736(03)12516-0
    • JP Ionnidis TA Trikalinos EE Ntzani DG Contopoulos-Ionnidis 2003 Genetic association in large versus small studies: an empirical assessment Lancet 361 567 571 10.1016/S0140-6736(03)12516-0
    • (2003) Lancet , vol.361 , pp. 567-571
    • Ionnidis, J.P.1    Trikalinos, T.A.2    Ntzani, E.E.3    Contopoulos-Ionnidis, D.G.4
  • 43
    • 0035679875 scopus 로고    scopus 로고
    • Population admixture may appear to mask, change or reverse genetic effects of genes underlying complex traits
    • 11729172
    • HW Deng 2001 Population admixture may appear to mask, change or reverse genetic effects of genes underlying complex traits Genetics 159 1319 1323 11729172
    • (2001) Genetics , vol.159 , pp. 1319-1323
    • Deng, H.W.1
  • 44
    • 2942756199 scopus 로고    scopus 로고
    • Meta-analysis of molecular association studies: Vitamin D receptor gene polymorphisms and BMD as a case study
    • 10.1359/JBMR.0301265 15040830
    • S Thakkinstian C D'Este J Eisman T Nguen J Attia 2004 Meta-analysis of molecular association studies: vitamin D receptor gene polymorphisms and BMD as a case study J Bone Miner Res 19 419 426 10.1359/JBMR.0301265 15040830
    • (2004) J Bone Miner Res , vol.19 , pp. 419-426
    • Thakkinstian, S.1    D'Este, C.2    Eisman, J.3    Nguen, T.4    Attia, J.5
  • 45
    • 33747115419 scopus 로고    scopus 로고
    • The association between common vitamin D receptor gene variations and osteoporosis: A participant-level meta-analysis
    • EPOS Investigators; EPOLOS Investigators; FAMOS Investigators; LASA Investigators; Rotterdam Study Investigators; GENOMOS Study et al. 16908916
    • AG Uitterlinden SH Ralston ML Brandi AH Carey D Grinberg EPOS Investigators; EPOLOS Investigators; FAMOS Investigators; LASA Investigators; Rotterdam Study Investigators; GENOMOS Study, et al. 2006 The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis Ann Intern Med 145 255 264 16908916
    • (2006) Ann Intern Med , vol.145 , pp. 255-264
    • Uitterlinden, A.G.1    Ralston, S.H.2    Brandi, M.L.3    Carey, A.H.4    Grinberg, D.5
  • 46
    • 17644367807 scopus 로고    scopus 로고
    • Functional analysis of the single-nucleotide polymorphism (787T>C) in tissue-nonspecific alkaline phosphatase gene associated with bone mineral density
    • 10.1359/JBMR.041229 15824850
    • M Goseki-Sone N Sogabe M Fukushi-Irie L Mizoi H Orimo T Suzuki H Nakamura H Orimo T Hosoi 2005 Functional analysis of the single-nucleotide polymorphism (787T>C) in tissue-nonspecific alkaline phosphatase gene associated with bone mineral density J Bone Miner Res 20 773 778 10.1359/JBMR.041229 15824850
    • (2005) J Bone Miner Res , vol.20 , pp. 773-778
    • Goseki-Sone, M.1    Sogabe, N.2    Fukushi-Irie, M.3    Mizoi, L.4    Orimo, H.5    Suzuki, T.6    Nakamura, H.7    Orimo, H.8    Hosoi, T.9
  • 47
    • 53149134698 scopus 로고    scopus 로고
    • Molecular effects of the tissue-nonspecific alkaline phosphatase gene polymorphism (787T>C) associated with bone mineral density
    • 10.2220/biomedres.29.213 18724009
    • N Sogabe K Oda H Nakamura H Orimo H Watanabe T Hosoi M Goseki-Sone 2008 Molecular effects of the tissue-nonspecific alkaline phosphatase gene polymorphism (787T>C) associated with bone mineral density Biomed Res 29 213 219 10.2220/biomedres.29.213 18724009
    • (2008) Biomed Res , vol.29 , pp. 213-219
    • Sogabe, N.1    Oda, K.2    Nakamura, H.3    Orimo, H.4    Watanabe, H.5    Hosoi, T.6    Goseki-Sone, M.7
  • 48
    • 44649087635 scopus 로고    scopus 로고
    • Functional analysis of the mutant tissue-nonspecific alkaline phosphatase gene using U2OS osteoblast-like cells
    • 10.1016/j.ymgme.2008.03.015 18455459
    • H Orimo M Goseki-Sone T Hosoi T Shimada 2008 Functional analysis of the mutant tissue-nonspecific alkaline phosphatase gene using U2OS osteoblast-like cells Mol Genet Metab 94 375 381 10.1016/j.ymgme.2008.03.015 18455459
    • (2008) Mol Genet Metab , vol.94 , pp. 375-381
    • Orimo, H.1    Goseki-Sone, M.2    Hosoi, T.3    Shimada, T.4
  • 50
    • 36349002288 scopus 로고    scopus 로고
    • Nutritional effects of gamma-glutamyl carboxylase gene polymorphism on the correlation between the vitamin K status and gamma-carboxylation of osteocalcin in young males
    • 10.3177/jnsv.53.419
    • N Sogabe N Tsugawa R Maruyama M Kamao H Kinoshita T Okano T Hosoi M Goseki-Sone 2007 Nutritional effects of gamma-glutamyl carboxylase gene polymorphism on the correlation between the vitamin K status and gamma-carboxylation of osteocalcin in young males J Nutr Sci Vitaminol (Tokyo) 53 419 425 10.3177/jnsv.53.419
    • (2007) J Nutr Sci Vitaminol (Tokyo) , vol.53 , pp. 419-425
    • Sogabe, N.1    Tsugawa, N.2    Maruyama, R.3    Kamao, M.4    Kinoshita, H.5    Okano, T.6    Hosoi, T.7    Goseki-Sone, M.8
  • 51
    • 18044386744 scopus 로고    scopus 로고
    • LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    • Osteoporosis-Pseudoglioma Syndrome Collaborative Group et al. 10.1016/S0092-8674(01)00571-2 11719191
    • Y Gong RB Slee N Fukai G Rawadi S Roman-Roman Osteoporosis-Pseudoglioma Syndrome Collaborative Group, et al. 2001 LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development Cell 107 513 523 10.1016/S0092-8674(01) 00571-2 11719191
    • (2001) Cell , vol.107 , pp. 513-523
    • Gong, Y.1    Slee, R.B.2    Fukai, N.3    Rawadi, G.4    Roman-Roman, S.5
  • 54
    • 3242781066 scopus 로고    scopus 로고
    • Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density
    • 10.1007/s00774-003-0492-9 15221492
    • T Urano M Shiraki Y Ezura M Fujita E Sekine S Hoshino T Hosoi H Orimo M Emi Y Ouchi S Inoue 2004 Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density J Bone Miner Metab 22 341 345 10.1007/s00774-003-0492-9 15221492
    • (2004) J Bone Miner Metab , vol.22 , pp. 341-345
    • Urano, T.1    Shiraki, M.2    Ezura, Y.3    Fujita, M.4    Sekine, E.5    Hoshino, S.6    Hosoi, T.7    Orimo, H.8    Emi, M.9    Ouchi, Y.10    Inoue, S.11
  • 55
    • 14844284570 scopus 로고    scopus 로고
    • Genetic disorders of the LRP5-Wnt signalling pathway affecting the skeleton
    • 10.1016/j.molmed.2005.01.004 15760771
    • M Audrey Koay MA Brown 2005 Genetic disorders of the LRP5-Wnt signalling pathway affecting the skeleton Trends Mol Med 11 129 137 10.1016/j.molmed.2005. 01.004 15760771
    • (2005) Trends Mol Med , vol.11 , pp. 129-137
    • Audrey Koay, M.1    Brown, M.A.2
  • 56
    • 33847720301 scopus 로고    scopus 로고
    • Association of a single-nucleotide variation (A1330V) in the low-density lipoprotein receptor protein 5 gene (LRP5) with bone mineral density in adult Japanese women
    • Y Ezura T Nakajima T Urano Y Sudo M Kajita H Yoshida T Suzuki T Hosoi S Inoue M Shiraki M Emi 2007 Association of a single-nucleotide variation (A1330V) in the low-density lipoprotein receptor protein 5 gene (LRP5) with bone mineral density in adult Japanese women Bone (NY) 40 997 1005
    • (2007) Bone (NY) , vol.40 , pp. 997-1005
    • Ezura, Y.1    Nakajima, T.2    Urano, T.3    Sudo, Y.4    Kajita, M.5    Yoshida, H.6    Suzuki, T.7    Hosoi, T.8    Inoue, S.9    Shiraki, M.10    Emi, M.11
  • 57
    • 61849164536 scopus 로고    scopus 로고
    • Genome-wide association study and follow-up replication studies identified ADAMTS18 an TGFBR3 as bone mass candidate genes in different ethnic groups
    • 10.1016/j.ajhg.2009.01.025 19249006
    • DH Xiong XG Liu YF Guo LJ Tan L Wang, et al. 2009 Genome-wide association study and follow-up replication studies identified ADAMTS18 an TGFBR3 as bone mass candidate genes in different ethnic groups Am J Hum Genet 84 388 398 10.1016/j.ajhg.2009.01.025 19249006
    • (2009) Am J Hum Genet , vol.84 , pp. 388-398
    • Xiong, D.H.1    Liu, X.G.2    Guo, Y.F.3    Tan, L.J.4    Wang, L.5
  • 58
    • 43049181624 scopus 로고    scopus 로고
    • Bone mineral density, osteoporosis, and osteoporotic fractures: A genome-wide association study
    • 10.1016/S0140-6736(08)60599-1 18455228
    • JB Richards F Rivadeneira M Inouye TM Pastinen N Soranzo, et al. 2008 Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study Lancet 371 1505 1512 10.1016/S0140-6736(08)60599-1 18455228
    • (2008) Lancet , vol.371 , pp. 1505-1512
    • Richards, J.B.1    Rivadeneira, F.2    Inouye, M.3    Pastinen, T.M.4    Soranzo, N.5
  • 60
    • 76249108602 scopus 로고    scopus 로고
    • Association of JAG1 with bone mineral density and osteoporotic fractures: A genome-wide association study and follow-up replication studies
    • 10.1016/j.ajhg.2009.12.014 20096396
    • AW Kung SM Xiao S Chemy GH Li Y Gao, et al. 2010 Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies Am J Hum Genet 86 229 239 10.1016/j.ajhg.2009.12.014 20096396
    • (2010) Am J Hum Genet , vol.86 , pp. 229-239
    • Kung, A.W.1    Xiao, S.M.2    Chemy, S.3    Li, G.H.4    Gao, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.