Functional assay of the mutant tissue-nonspecific alkaline phosphatase gene using U2OS osteoblast-like cells

Molecular Genetics and Metabolism

Volumn 94, Issue 3, 2008, Pages 375-381

  Orimo, Hideo ^a   Goseki Sone, Masae ^b   Hosoi, Takayuki ^c   Shimada, Takashi ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b JAPAN WOMEN'S UNIVERSITY   (Japan)

^c NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Hypophosphatasia; Mineralization; Tissue nonspecific alkaline phosphatase; U2OS cells

Indexed keywords

5' NUCLEOTIDASE; ALKALINE PHOSPHATASE; GLYCEROL 2 PHOSPHATE; MESSENGER RNA; MUTANT PROTEIN; PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE;

ARTICLE; BONE MINERALIZATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOPHOSPHATASIA; OSTEOBLAST; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS;

ALKALINE PHOSPHATASE; CALCIFICATION, PHYSIOLOGIC; CELL LINE; ENZYME ACTIVATION; GLYCEROPHOSPHATES; HUMANS; MOLECULAR DIAGNOSTIC TECHNIQUES; MUTANT PROTEINS; OSTEOBLASTS; PHEX PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, MESSENGER; TRANSFECTION;

EID: 44649087635     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2008.03.015     Document Type: Article

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