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Volumn 21, Issue 3, 2006, Pages 424-437

Genome-wide scan identified QTLs underlying femoral neck cross-sectional geometry that are novel studied risk factors of osteoporosis

Author keywords

Femoral neck cross sectional geometry; Hip fracture; Osteoporosis; Whole genome linkage scan

Indexed keywords

ADULT; AGED; ARTICLE; CHROMOSOME 20Q; EPISTASIS; FEMALE; FEMUR NECK; FEMUR NECK CROSS SECTIONAL GEOMETRY; GENDER; GENETIC LINKAGE; GENETIC SCREENING; GENETIC VARIABILITY; GENOME; GEOMETRY; HIP FRACTURE; HUMAN; MAJOR CLINICAL STUDY; MALE; MUSCULOSKELETAL SYSTEM PARAMETERS; OSTEOPOROSIS; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; RISK FACTOR; STATISTICAL ANALYSIS; X CHROMOSOME;

EID: 33644541419     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.051202     Document Type: Article
Times cited : (38)

References (88)
  • 1
    • 0037129560 scopus 로고    scopus 로고
    • Epidemiology and outcomes of osteoporotic fractures
    • Cummings SR, Melton LJ 2002 Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761-1767.
    • (2002) Lancet , vol.359 , pp. 1761-1767
    • Cummings, S.R.1    Melton, L.J.2
  • 3
    • 0037347604 scopus 로고    scopus 로고
    • Estimating hip fracture morbidity, mortality and costs
    • Braithwaite RS, Col NF, Wong JB 2003 Estimating hip fracture morbidity, mortality and costs. J Am Geriatr Soc 51:364-370.
    • (2003) J Am Geriatr Soc , vol.51 , pp. 364-370
    • Braithwaite, R.S.1    Col, N.F.2    Wong, J.B.3
  • 5
    • 0023300017 scopus 로고
    • Hip fracture: A prospective study of hospital course, complications, and costs
    • Campion EW, Jette AM, Cleary PD, Harris BA 1987 Hip fracture: A prospective study of hospital course, complications, and costs. J Gen Intern Med 2:78-82.
    • (1987) J Gen Intern Med , vol.2 , pp. 78-82
    • Campion, E.W.1    Jette, A.M.2    Cleary, P.D.3    Harris, B.A.4
  • 6
    • 29144535359 scopus 로고    scopus 로고
    • Economic evaluations of interventions for the prevention and treatment of osteoporosis: A structured review of the literature
    • Fleurence RL, Iglesias CP, Torgerson DJ 2005 Economic evaluations of interventions for the prevention and treatment of osteoporosis: A structured review of the literature. Osteoporos Int 17:29-40.
    • (2005) Osteoporos Int , vol.17 , pp. 29-40
    • Fleurence, R.L.1    Iglesias, C.P.2    Torgerson, D.J.3
  • 7
    • 0030910104 scopus 로고    scopus 로고
    • Hip fractures. Epidemiology, risk factors, falls, energy absorption, hip protectors, and prevention
    • Lauritzen JB 1997 Hip fractures. Epidemiology, risk factors, falls, energy absorption, hip protectors, and prevention. Dan Med Bull 44:155-168.
    • (1997) Dan Med Bull , vol.44 , pp. 155-168
    • Lauritzen, J.B.1
  • 10
    • 0141499867 scopus 로고    scopus 로고
    • Bone strength and its determinants
    • Ammann P, Rizzoli R 2003 Bone strength and its determinants. Osteoporos Int 14(Suppl 3):S13-S18.
    • (2003) Osteoporos Int , vol.14 , Issue.SUPPL. 3
    • Ammann, P.1    Rizzoli, R.2
  • 11
    • 2142707313 scopus 로고    scopus 로고
    • Combination of bone mineral density and upper femur geometry improves the prediction of hip fracture
    • Pulkkinen P, Partanen J, Jalovaara P, Jamsa T 2004 Combination of bone mineral density and upper femur geometry improves the prediction of hip fracture. Osteoporos Int 15:274-280.
    • (2004) Osteoporos Int , vol.15 , pp. 274-280
    • Pulkkinen, P.1    Partanen, J.2    Jalovaara, P.3    Jamsa, T.4
  • 12
    • 0033814696 scopus 로고    scopus 로고
    • Cross-sectional geometry, bone strength, and bone mass in the proximal femur in black and white postmenopausal women
    • Nelson DA, Barondess DA, Hendrix SL, Beck TJ 2000 Cross-sectional geometry, bone strength, and bone mass in the proximal femur in black and white postmenopausal women. J Bone Miner Res 15:1992-1997.
    • (2000) J Bone Miner Res , vol.15 , pp. 1992-1997
    • Nelson, D.A.1    Barondess, D.A.2    Hendrix, S.L.3    Beck, T.J.4
  • 15
    • 0142241146 scopus 로고    scopus 로고
    • Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging
    • Duan Y, Beck TJ, Wang XF, Seeman E 2003 Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging. J Bone Miner Res 18:1766-1774.
    • (2003) J Bone Miner Res , vol.18 , pp. 1766-1774
    • Duan, Y.1    Beck, T.J.2    Wang, X.F.3    Seeman, E.4
  • 16
    • 16644367476 scopus 로고    scopus 로고
    • The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: The Rotterdam Study
    • Rivadeneira F, Houwing-Duistermaat JJ, Beck TJ, Janssen JA, Hofman A, Pols HA, Van Duijn CM, Uitterlinden AG 2004 The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: The Rotterdam Study. J Bone Miner Res 19:1280-1290.
    • (2004) J Bone Miner Res , vol.19 , pp. 1280-1290
    • Rivadeneira, F.1    Houwing-Duistermaat, J.J.2    Beck, T.J.3    Janssen, J.A.4    Hofman, A.5    Pols, H.A.6    Van Duijn, C.M.7    Uitterlinden, A.G.8
  • 21
    • 29044431732 scopus 로고    scopus 로고
    • Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families
    • Xiong DH, Liu YZ, Liu PY, Zhao LJ, Deng HW 2005 Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families. Osteoporos Int 16:2113-2122.
    • (2005) Osteoporos Int , vol.16 , pp. 2113-2122
    • Xiong, D.H.1    Liu, Y.Z.2    Liu, P.Y.3    Zhao, L.J.4    Deng, H.W.5
  • 22
    • 14344259508 scopus 로고    scopus 로고
    • Nonreplication in genetic studies of complex diseases-lessons learned from studies of osteoporosis and tentative remedies
    • Shen H, Liu Y, Liu P, Recker RR, Deng HW 2005 Nonreplication in genetic studies of complex diseases-lessons learned from studies of osteoporosis and tentative remedies. J Bone Miner Res 20:365-376.
    • (2005) J Bone Miner Res , vol.20 , pp. 365-376
    • Shen, H.1    Liu, Y.2    Liu, P.3    Recker, R.R.4    Deng, H.W.5
  • 24
    • 0036217241 scopus 로고    scopus 로고
    • Determination of bone size of hip, spine, and wrist in human pedigrees by genetic and lifestyle factors
    • Deng HW, Deng XT, Conway T, Xu FH, Heaney R, Recker RR 2002 Determination of bone size of hip, spine, and wrist in human pedigrees by genetic and lifestyle factors. J Clin Densitom 5:45-56.
    • (2002) J Clin Densitom , vol.5 , pp. 45-56
    • Deng, H.W.1    Deng, X.T.2    Conway, T.3    Xu, F.H.4    Heaney, R.5    Recker, R.R.6
  • 26
    • 0036136714 scopus 로고    scopus 로고
    • Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases
    • Deng HW, Mahaney MC, Williams JT, Li J, Conway T, Davies KM, Li JL, Deng H, Recker RR 2002 Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases. Genet Epidemiol 22:12-25.
    • (2002) Genet Epidemiol , vol.22 , pp. 12-25
    • Deng, H.W.1    Mahaney, M.C.2    Williams, J.T.3    Li, J.4    Conway, T.5    Davies, K.M.6    Li, J.L.7    Deng, H.8    Recker, R.R.9
  • 28
    • 0033814755 scopus 로고    scopus 로고
    • Characterization of petimenopausal bone loss: A prospective study
    • Recker R, Lappe J, Davies K, Heaney R 2000 Characterization of petimenopausal bone loss: A prospective study. J Bone Miner Res 15:1965-1973.
    • (2000) J Bone Miner Res , vol.15 , pp. 1965-1973
    • Recker, R.1    Lappe, J.2    Davies, K.3    Heaney, R.4
  • 29
    • 44649202834 scopus 로고    scopus 로고
    • Measuring the structural strength of bones with dual-energy X-ray absorptiometry: Principles, technical limitations, and future possibilities
    • Beck T 2003 Measuring the structural strength of bones with dual-energy X-ray absorptiometry: Principles, technical limitations, and future possibilities. Osteoporos Int 14(Suppl 5):81-88.
    • (2003) Osteoporos Int , vol.14 , Issue.SUPPL. 5 , pp. 81-88
    • Beck, T.1
  • 30
    • 0034925238 scopus 로고    scopus 로고
    • Toward high-throughput genotyping: Dynamic and automatic software for manipulating large-scale genotype data using fluorescently labeled dinucleotide markers
    • Li JL, Deng H, Lai DB, Xu F, Chen J, Gao G, Recker RR, Deng HW 2001 Toward high-throughput genotyping: Dynamic and automatic software for manipulating large-scale genotype data using fluorescently labeled dinucleotide markers. Genome Res 11:1304-1314.
    • (2001) Genome Res , vol.11 , pp. 1304-1314
    • Li, J.L.1    Deng, H.2    Lai, D.B.3    Xu, F.4    Chen, J.5    Gao, G.6    Recker, R.R.7    Deng, H.W.8
  • 31
    • 0032231941 scopus 로고    scopus 로고
    • PedCheck: A program for identification of genotype incompatibilities in linkage analysis
    • O'Connell JR, Weeks DE 1998 PedCheck: A program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 63:259-266.
    • (1998) Am J Hum Genet , vol.63 , pp. 259-266
    • O'Connell, J.R.1    Weeks, D.E.2
  • 32
    • 0036338150 scopus 로고    scopus 로고
    • Merlin-rapid analysis of dense genetic maps using sparse gene flow trees
    • Abecasis GR, Cherny SS, Cookson WO, Cardon LR 2002 Merlin-rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 30:97-101.
    • (2002) Nat Genet , vol.30 , pp. 97-101
    • Abecasis, G.R.1    Cherny, S.S.2    Cookson, W.O.3    Cardon, L.R.4
  • 33
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L, Blangero J 1998 Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198-1211.
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 34
    • 0028058128 scopus 로고
    • Robust variance-components approach for assessing genetic linkage in pedigrees
    • Amos CI 1994 Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet 54:535-543.
    • (1994) Am J Hum Genet , vol.54 , pp. 535-543
    • Amos, C.I.1
  • 35
    • 0029875522 scopus 로고    scopus 로고
    • Assessing genetic linkage and association with robust components of variance approaches
    • Amos CI, Zhu DK, Boerwinkle E 1996 Assessing genetic linkage and association with robust components of variance approaches. Ann Hum Genet 60:143-160.
    • (1996) Ann Hum Genet , vol.60 , pp. 143-160
    • Amos, C.I.1    Zhu, D.K.2    Boerwinkle, E.3
  • 36
    • 0033358545 scopus 로고    scopus 로고
    • Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure
    • Allison DB, Neale MC, Zannolli R, Schork NJ, Amos CI, Blangero J 1999 Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure. Am J Hum Genet 65:531-544.
    • (1999) Am J Hum Genet , vol.65 , pp. 531-544
    • Allison, D.B.1    Neale, M.C.2    Zannolli, R.3    Schork, N.J.4    Amos, C.I.5    Blangero, J.6
  • 37
    • 0033820011 scopus 로고    scopus 로고
    • Robust LOD scores for variance component-based linkage analysis
    • Blangero J, Williams JT, Almasy L 2000 Robust LOD scores for variance component-based linkage analysis. Genet Epidemiol 19(Suppl 1):S8-S14.
    • (2000) Genet Epidemiol , vol.19 , Issue.SUPPL. 1
    • Blangero, J.1    Williams, J.T.2    Almasy, L.3
  • 39
    • 0029886532 scopus 로고    scopus 로고
    • Parametric and nonparametric linkage analysis: A unified multipoint approach
    • Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES 1996 Parametric and nonparametric linkage analysis: A unified multipoint approach. Am J Hum Genet 58:1347-1363.
    • (1996) Am J Hum Genet , vol.58 , pp. 1347-1363
    • Kruglyak, L.1    Daly, M.J.2    Reeve-Daly, M.P.3    Lander, E.S.4
  • 40
    • 0035717141 scopus 로고    scopus 로고
    • Correcting for multiple analyses in genomewide linkage studies
    • Camp NJ, Farnham JM 2001 Correcting for multiple analyses in genomewide linkage studies. Ann Hum Genet 65:577-582.
    • (2001) Ann Hum Genet , vol.65 , pp. 577-582
    • Camp, N.J.1    Farnham, J.M.2
  • 42
    • 26944493073 scopus 로고    scopus 로고
    • The importance of modelling heterogeneity in complex disease: Application to NIMH Schizophrenia Genetics Initiative data
    • Holliday E, Mowry B, Chant D, Nyholt D 2005 The importance of modelling heterogeneity in complex disease: Application to NIMH Schizophrenia Genetics Initiative data. Hum Genet 117:160-167.
    • (2005) Hum Genet , vol.117 , pp. 160-167
    • Holliday, E.1    Mowry, B.2    Chant, D.3    Nyholt, D.4
  • 44
    • 0034751519 scopus 로고    scopus 로고
    • Clinical review 137: Sexual dimorphism in skeletal size, density, and strength
    • Seeman E 2001 Clinical review 137: Sexual dimorphism in skeletal size, density, and strength. J Clin Endocrinol Metab 86:4576-4584.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4576-4584
    • Seeman, E.1
  • 45
    • 0037785145 scopus 로고    scopus 로고
    • Sex- and race-related differences in cross-sectional geometry and bone density of the femoral mid-shaft in older adults
    • Taaffe DR, Lang TF, Fuerst T, Cauley JA, Nevitt MC, Harris TB 2003 Sex- and race-related differences in cross-sectional geometry and bone density of the femoral mid-shaft in older adults. Ann Hum Biol 30:329-346.
    • (2003) Ann Hum Biol , vol.30 , pp. 329-346
    • Taaffe, D.R.1    Lang, T.F.2    Fuerst, T.3    Cauley, J.A.4    Nevitt, M.C.5    Harris, T.B.6
  • 46
    • 0033725189 scopus 로고    scopus 로고
    • Structural trends in the aging femoral neck and proximal shaft: Analysis of the Third National Health and Nutrition Examination Survey dual-energy X-ray absorptiometry data
    • Beck TJ, Looker AC, Ruff CB, Sievanen H, Wahner HW 2000 Structural trends in the aging femoral neck and proximal shaft: Analysis of the Third National Health and Nutrition Examination Survey dual-energy X-ray absorptiometry data. J Bone Miner Res 15:2297-2304.
    • (2000) J Bone Miner Res , vol.15 , pp. 2297-2304
    • Beck, T.J.1    Looker, A.C.2    Ruff, C.B.3    Sievanen, H.4    Wahner, H.W.5
  • 48
    • 0027260534 scopus 로고
    • Age-related changes in female femoral neck geometry. Implications for bone strength
    • Beck TJ, Ruff CB, Bissessur K 1993 Age-related changes in female femoral neck geometry. Implications for bone strength. Calcif Tissue Int 53(Suppl 1):S41-S46.
    • (1993) Calcif Tissue Int , vol.53 , Issue.SUPPL. 1
    • Beck, T.J.1    Ruff, C.B.2    Bissessur, K.3
  • 50
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander E, Kruglyak L 1995 Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247.
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 51
    • 1342311195 scopus 로고    scopus 로고
    • Femoral neck fragility in women has its structural and biomechanical basis established by periosteal modeling during growth and endocortical remodeling during aging
    • Filardi S, Zebaze RM, Duan Y, Edmonds J, Beck T, Seeman E 2004 Femoral neck fragility in women has its structural and biomechanical basis established by periosteal modeling during growth and endocortical remodeling during aging. Osteoporos Int 15:103-107.
    • (2004) Osteoporos Int , vol.15 , pp. 103-107
    • Filardi, S.1    Zebaze, R.M.2    Duan, Y.3    Edmonds, J.4    Beck, T.5    Seeman, E.6
  • 53
    • 0034782662 scopus 로고    scopus 로고
    • Effects of current and discontinued estrogen replacement therapy on hip structural geometry: The study of osteoporotic fractures
    • Beck TJ, Stone KL, Oreskovic TL, Hochberg MC, Nevitt MC, Genant HK, Cummings SR 2001 Effects of current and discontinued estrogen replacement therapy on hip structural geometry: The study of osteoporotic fractures. J Bone Miner Res 16:2103-2110.
    • (2001) J Bone Miner Res , vol.16 , pp. 2103-2110
    • Beck, T.J.1    Stone, K.L.2    Oreskovic, T.L.3    Hochberg, M.C.4    Nevitt, M.C.5    Genant, H.K.6    Cummings, S.R.7
  • 54
    • 4344657882 scopus 로고    scopus 로고
    • Femoral bpne structural geometry adapts to mechanical loading and is influenced by sex steroids: The Penn State Young Women's Health Study
    • Petit MA, Beck TJ, Lin HM, Bentley C, Legro RS, Lloyd T 2004 Femoral bpne structural geometry adapts to mechanical loading and is influenced by sex steroids: The Penn State Young Women's Health Study. Bone 35:750-759.
    • (2004) Bone , vol.35 , pp. 750-759
    • Petit, M.A.1    Beck, T.J.2    Lin, H.M.3    Bentley, C.4    Legro, R.S.5    Lloyd, T.6
  • 55
    • 0028262987 scopus 로고
    • Prediction of hip fractures from pelvic radiographs: The study of osteoporotic fractures
    • The Study of Osteoporotic Fractures Research Group
    • Gluer CC, Cummings SR, Pressman A, Li J, Gluer K, Faulkner KG, Grampp S, Genant HK 1994 Prediction of hip fractures from pelvic radiographs: The study of osteoporotic fractures. The Study of Osteoporotic Fractures Research Group. J Bone Miner Res 9:671-677.
    • (1994) J Bone Miner Res , vol.9 , pp. 671-677
    • Gluer, C.C.1    Cummings, S.R.2    Pressman, A.3    Li, J.4    Gluer, K.5    Faulkner, K.G.6    Grampp, S.7    Genant, H.K.8
  • 56
    • 0029841074 scopus 로고    scopus 로고
    • Prediction of fracture load at different skeletal sites by geometric properties of the cortical shell
    • Augat P, Reeb H, Claes LE 1996 Prediction of fracture load at different skeletal sites by geometric properties of the cortical shell. J Bone Miner Res 11:1356-1363.
    • (1996) J Bone Miner Res , vol.11 , pp. 1356-1363
    • Augat, P.1    Reeb, H.2    Claes, L.E.3
  • 59
    • 0028126646 scopus 로고
    • Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development
    • Chang SC, Hoang B, Thomas JT, Vukicevic S, Luyten FP, Ryba NJ, Kozak CA, Reddi AH, Moos M Jr 1994 Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development. J Biol Chem 269:28227-28234.
    • (1994) J Biol Chem , vol.269 , pp. 28227-28234
    • Chang, S.C.1    Hoang, B.2    Thomas, J.T.3    Vukicevic, S.4    Luyten, F.P.5    Ryba, N.J.6    Kozak, C.A.7    Reddi, A.H.8    Moos Jr., M.9
  • 63
    • 0842306340 scopus 로고    scopus 로고
    • Association of a polymorphism of the matrix metalloproteinase-9 gene with bone mineral density in Japanese men
    • Yamada Y, Ando F, Niino N, Shimokata H 2004 Association of a polymorphism of the matrix metalloproteinase-9 gene with bone mineral density in Japanese men. Metabolism 53:135-137.
    • (2004) Metabolism , vol.53 , pp. 135-137
    • Yamada, Y.1    Ando, F.2    Niino, N.3    Shimokata, H.4
  • 64
    • 0030740253 scopus 로고    scopus 로고
    • Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
    • Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM 1997 Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell 90:569-580.
    • (1997) Cell , vol.90 , pp. 569-580
    • Chen, H.1    Lin, R.J.2    Schiltz, R.L.3    Chakravarti, D.4    Nash, A.5    Nagy, L.6    Privalsky, M.L.7    Nakatani, Y.8    Evans, R.M.9
  • 65
    • 33644516144 scopus 로고    scopus 로고
    • Nuclear receptor coativator-3 (NCO A3/AIB1/SRC3) alleles are a strong correlate of bioavailable testosterone and vertebral bone mass in older men
    • Zmuda JM, Cauley JA, Ferrel RE 2004 Nuclear receptor coativator-3 (NCO A3/AIB1/SRC3) alleles are a strong correlate of bioavailable testosterone and vertebral bone mass in older men. J Bone Miner Res 19:S387.
    • (2004) J Bone Miner Res , vol.19
    • Zmuda, J.M.1    Cauley, J.A.2    Ferrel, R.E.3
  • 68
    • 0037303461 scopus 로고    scopus 로고
    • Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density
    • Shultz KL, Donahue LR, Bouxsein ML, Baylink DJ, Rosen CJ, Beamer WG 2003 Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density. J Bone Miner Res 18:175-185.
    • (2003) J Bone Miner Res , vol.18 , pp. 175-185
    • Shultz, K.L.1    Donahue, L.R.2    Bouxsein, M.L.3    Baylink, D.J.4    Rosen, C.J.5    Beamer, W.G.6
  • 69
    • 0041331738 scopus 로고    scopus 로고
    • Age, gender, and body mass effects on quantitative trait loci for bone mineral density: The Framingham Study
    • Karasik D, Cupples LA, Hannan MT, Kiel DP 2003 Age, gender, and body mass effects on quantitative trait loci for bone mineral density: The Framingham Study. Bone 33:308-316.
    • (2003) Bone , vol.33 , pp. 308-316
    • Karasik, D.1    Cupples, L.A.2    Hannan, M.T.3    Kiel, D.P.4
  • 71
    • 33644507278 scopus 로고    scopus 로고
    • Low DXA and CT bone measures in young adults with a simple sequence repeat in IGF-I gene
    • Liu X, Rosen C, Mora S, Dong D, Pitukcheewanont P, Gilsanz V 2004 Low DXA and CT Bone Measures in Young Adults with a Simple Sequence Repeat in IGF-I Gene. J Bone Miner Res 19:8248.
    • (2004) J Bone Miner Res , vol.19 , pp. 8248
    • Liu, X.1    Rosen, C.2    Mora, S.3    Dong, D.4    Pitukcheewanont, P.5    Gilsanz, V.6
  • 72
    • 0028177078 scopus 로고
    • Lumbar vertebral and femoral neck bone mineral density are higher in postmenopausal women with the alpha 2HS-glycoprotein 2 phenotype
    • Dickson IR, Gwilliam R, Arora M, Murphy S, Khaw KT, Phillips C, Lincoln P 1994 Lumbar vertebral and femoral neck bone mineral density are higher in postmenopausal women with the alpha 2HS-glycoprotein 2 phenotype. Bone Miner 24:181-188.
    • (1994) Bone Miner , vol.24 , pp. 181-188
    • Dickson, I.R.1    Gwilliam, R.2    Arora, M.3    Murphy, S.4    Khaw, K.T.5    Phillips, C.6    Lincoln, P.7
  • 80
    • 0036252133 scopus 로고    scopus 로고
    • Genetic dissection of femur breaking strength in a large population (MRL/MpJ × SJL/J) of F2 Mice: Single QTL effects, epistasis, and pleiotropy
    • Li X, Masinde G, Gu W, Wergedal J, Mohan S, Baylink DJ 2002 Genetic dissection of femur breaking strength in a large population (MRL/MpJ × SJL/J) of F2 Mice: Single QTL effects, epistasis, and pleiotropy. Genomics 79:734-740.
    • (2002) Genomics , vol.79 , pp. 734-740
    • Li, X.1    Masinde, G.2    Gu, W.3    Wergedal, J.4    Mohan, S.5    Baylink, D.J.6
  • 82
    • 0036594821 scopus 로고    scopus 로고
    • Relationship among VDR (BsmI and FokI), COLIA1, and CTR polymorphisms with bone mass, bone turnover markers, and sex hormones in men
    • Braga V, Sangalli A, Malerba G, Mottes M, Mirandola S, Gatti D, Rossini M, Zamboni M, Adami S 2002 Relationship among VDR (BsmI and FokI), COLIA1, and CTR polymorphisms with bone mass, bone turnover markers, and sex hormones in men. Calcif Tissue Int 70:457-162.
    • (2002) Calcif Tissue Int , vol.70 , pp. 457-1162
    • Braga, V.1    Sangalli, A.2    Malerba, G.3    Mottes, M.4    Mirandola, S.5    Gatti, D.6    Rossini, M.7    Zamboni, M.8    Adami, S.9
  • 87
    • 0035209177 scopus 로고    scopus 로고
    • Large upward bias in estimation of locus-specific effects from genomewide scans
    • Goring HH, Terwilliger JD, Blangero J 2001 Large upward bias in estimation of locus-specific effects from genomewide scans. Am J Hum Genet 69:1357-1369.
    • (2001) Am J Hum Genet , vol.69 , pp. 1357-1369
    • Goring, H.H.1    Terwilliger, J.D.2    Blangero, J.3
  • 88
    • 0036844237 scopus 로고    scopus 로고
    • Upward bias in estimation of genetic effects
    • Siegmund D 2002 Upward bias in estimation of genetic effects. Am J Hum Genet 71:1183-1188.
    • (2002) Am J Hum Genet , vol.71 , pp. 1183-1188
    • Siegmund, D.1


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