Functional analysis of the single nucleotide polymorphism (787T>C) in the Tissue-Nonspecific Alkaline Phosphatase gene associated with BMD

Journal of Bone and Mineral Research

Volumn 20, Issue 5, 2005, Pages 773-782

  Goseki Sone, Masae ^a   Sogabe, Natsuko ^a   Fukushi Irie, Mariko ^a   Mizoi, Lena ^a   Orimo, Hideo ^b   Suzuki, Takao ^c   Nakamura, Hiroyuki ^d   Orimo, Hajime ^e   Hosoi, Takayuki ^f  

^a JAPAN WOMEN'S UNIVERSITY   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^d GAKUSHUIN UNIVERSITY   (Japan)

^e Health Science University   (Japan)

^f Tokyo Metropolitan Institute of Gerontology   (Japan)

Author keywords

BMD; Expression vector; Osteoporosis; Single nucleotide polymorphism; Tissue nonspecific alkaline phosphatase

Indexed keywords

ALKALINE PHOSPHATASE; COMPLEMENTARY DNA;

ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; BONE DENSITOMETRY; BONE DENSITY; BONE MINERALIZATION; CATALYSIS; CELL TYPE; FEMALE; GENE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC TRANSFECTION; HAPLOTYPE; HETEROZYGOTE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; POSTMENOPAUSE; RECEPTOR AFFINITY; SINGLE NUCLEOTIDE POLYMORPHISM; TISSUE SPECIFICITY; TNSALP GENE;

AGED; AGED, 80 AND OVER; ALKALINE PHOSPHATASE; ANIMALS; BLOTTING, WESTERN; BONE DENSITY; CATALYSIS; CELL LINE; CELL LINE, TUMOR; COS CELLS; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HOMOZYGOTE; HUMANS; HYDROLYSIS; KINETICS; LINKAGE DISEQUILIBRIUM; MODELS, MOLECULAR; OSTEOPOROSIS; PLASMIDS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; POSTMENOPAUSE; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; TRANSFECTION;

EID: 17644367807     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.041229     Document Type: Article

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