-
2
-
-
0035830506
-
Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton
-
Hartmann C., and Tabin D.J. Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. Cell 140 (2001) 341-351
-
(2001)
Cell
, vol.140
, pp. 341-351
-
-
Hartmann, C.1
Tabin, D.J.2
-
3
-
-
0037347909
-
Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation
-
Yang Y., Topol L., Lee H., and Wu J. Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation. Development 130 (2003) 1003-1015
-
(2003)
Development
, vol.130
, pp. 1003-1015
-
-
Yang, Y.1
Topol, L.2
Lee, H.3
Wu, J.4
-
4
-
-
0037092049
-
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
-
Kato M., Patel M.S., Levasseur R., Lobov I., Chang B.H.J., Glass II D.A., et al. Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J. Cell Biol. 157 (2002) 303-314
-
(2002)
J. Cell Biol.
, vol.157
, pp. 303-314
-
-
Kato, M.1
Patel, M.S.2
Levasseur, R.3
Lobov, I.4
Chang, B.H.J.5
Glass II, D.A.6
-
5
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to axin and regulates the canonical Wnt signaling pathway
-
Mao J., Wang J., Liu B., Pan W., Farr III G.H., Flynn C., et al. Low-density lipoprotein receptor-related protein-5 binds to axin and regulates the canonical Wnt signaling pathway. Mol. Cell 7 (2001) 801-809
-
(2001)
Mol. Cell
, vol.7
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
Pan, W.4
Farr III, G.H.5
Flynn, C.6
-
6
-
-
0035822594
-
Wnt signaling: antagonistic Dickkopfs
-
Zorn A.M. Wnt signaling: antagonistic Dickkopfs. Curr. Biol. 11 (2001) R592-R595
-
(2001)
Curr. Biol.
, vol.11
-
-
Zorn, A.M.1
-
7
-
-
0029937085
-
Osteoporosis-pseudoglioma syndrome, a disorder affecting skeletal strength and vision, is assigned to chromosome region 11q12-13
-
Gong Y., Vikkula M., Boon L., Liu J., Beighton P., Ramesar R., et al. Osteoporosis-pseudoglioma syndrome, a disorder affecting skeletal strength and vision, is assigned to chromosome region 11q12-13. Am. J. Hum. Genet. 59 (1996) 146-151
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 146-151
-
-
Gong, Y.1
Vikkula, M.2
Boon, L.3
Liu, J.4
Beighton, P.5
Ramesar, R.6
-
8
-
-
18044386744
-
LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
-
Gong Y., Slee R.B., Fukai N., Rawadi G., Roman-Roman S., Reginato A.M., et al. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 107 (2001) 513-523
-
(2001)
Cell
, vol.107
, pp. 513-523
-
-
Gong, Y.1
Slee, R.B.2
Fukai, N.3
Rawadi, G.4
Roman-Roman, S.5
Reginato, A.M.6
-
9
-
-
0036138175
-
A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait
-
Little R.D., Carulli J.P., Del Mastro R.G., Dupuis J., Osborne M., Folz C., et al. A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am. J. Hum. Genet. 70 (2002) 11-19
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 11-19
-
-
Little, R.D.1
Carulli, J.P.2
Del Mastro, R.G.3
Dupuis, J.4
Osborne, M.5
Folz, C.6
-
10
-
-
0037118285
-
High bone density due to a mutation in LDL-receptor-related protein 5
-
Boyden L.M., Mao J., Belsky J., Mitzner L., Farhi A., Mitnick M.A., et al. High bone density due to a mutation in LDL-receptor-related protein 5. N. Engl. J. Med. 346 (2002) 1513-1521
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1513-1521
-
-
Boyden, L.M.1
Mao, J.2
Belsky, J.3
Mitzner, L.4
Farhi, A.5
Mitnick, M.A.6
-
11
-
-
0037373341
-
Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density
-
Van Wesenbeeck L., Cleiren E., Gram J., Beals R.K., Benichou O., Scopelliti D., et al. Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density. Am. J. Hum. Genet. 72 (2003) 763-771
-
(2003)
Am. J. Hum. Genet.
, vol.72
, pp. 763-771
-
-
Van Wesenbeeck, L.1
Cleiren, E.2
Gram, J.3
Beals, R.K.4
Benichou, O.5
Scopelliti, D.6
-
12
-
-
0029836744
-
Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I α 1 gene
-
Grant S.FA., Reid D.M., Blake G., Herd R., Fogelman I., and Ralston S.H. Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I α 1 gene. Nat. Genet. 14 (1996) 203-205
-
(1996)
Nat. Genet.
, vol.14
, pp. 203-205
-
-
Grant, S.FA.1
Reid, D.M.2
Blake, G.3
Herd, R.4
Fogelman, I.5
Ralston, S.H.6
-
13
-
-
0035135523
-
A candidate prostate cancer susceptibility gene at chromosome 17p
-
Tavtigian S.V., Simard J., Teng D.H., Abtin V., Baumgard M., Beck A., et al. A candidate prostate cancer susceptibility gene at chromosome 17p. Nat. Genet. 27 (2001) 172-224
-
(2001)
Nat. Genet.
, vol.27
, pp. 172-224
-
-
Tavtigian, S.V.1
Simard, J.2
Teng, D.H.3
Abtin, V.4
Baumgard, M.5
Beck, A.6
-
14
-
-
0033804457
-
Association of HPC2/ELAC2 genotypes and prostate cancer
-
Rebbeck T.R., Walker A.H., Zeigler-Johnson C., Weisburg S., Martin A.M., Nathanson K.L., et al. Association of HPC2/ELAC2 genotypes and prostate cancer. Am. J. Hum. Genet. 67 (2000) 1014-1019
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 1014-1019
-
-
Rebbeck, T.R.1
Walker, A.H.2
Zeigler-Johnson, C.3
Weisburg, S.4
Martin, A.M.5
Nathanson, K.L.6
-
15
-
-
3242781066
-
Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density
-
Urano T., Shiraki M., Ezura Y., Fujita M., Sekine E., Hoshino S., et al. Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density. J. Bone Miner. Metab. 22 (2004) 341-345
-
(2004)
J. Bone Miner. Metab.
, vol.22
, pp. 341-345
-
-
Urano, T.1
Shiraki, M.2
Ezura, Y.3
Fujita, M.4
Sekine, E.5
Hoshino, S.6
-
16
-
-
12144287023
-
LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density
-
Mizuguchi T., Furuta I., Watanabe Y., Tsukamoto K., Tomita H., Tsujihata M., et al. LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density. J. Hum. Genet. 49 (2004) 80-86
-
(2004)
J. Hum. Genet.
, vol.49
, pp. 80-86
-
-
Mizuguchi, T.1
Furuta, I.2
Watanabe, Y.3
Tsukamoto, K.4
Tomita, H.5
Tsujihata, M.6
-
17
-
-
3042752105
-
Association between bone mineral density and LDL receptor-related protein 5 gene polymorphisms in young Korean men
-
Koh J.M., Jung M.H., Hong J.S., Park H.J., Chang J.S., Shin H.D., et al. Association between bone mineral density and LDL receptor-related protein 5 gene polymorphisms in young Korean men. J. Korean Med. Sci. 19 (2004) 407-412
-
(2004)
J. Korean Med. Sci.
, vol.19
, pp. 407-412
-
-
Koh, J.M.1
Jung, M.H.2
Hong, J.S.3
Park, H.J.4
Chang, J.S.5
Shin, H.D.6
-
18
-
-
2342529785
-
Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites
-
Ferrari S.L., Deutsh S., Choudhury U., Chevalley T., Bonjour J.P., Dermitzakis E.T., et al. Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites. Am. J. Hum. Genet. 74 (2004) 866-875
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 866-875
-
-
Ferrari, S.L.1
Deutsh, S.2
Choudhury, U.3
Chevalley, T.4
Bonjour, J.P.5
Dermitzakis, E.T.6
-
19
-
-
0034765632
-
Diagnostic criteria for primary osteoporosis: year 2000 revision
-
Orimo H., Hayashi Y., Fukunaga M., Sone T., Fujiwara M., Shiraki M., et al. Diagnostic criteria for primary osteoporosis: year 2000 revision. J. Bone Miner. Metab. 19 (2001) 331-337
-
(2001)
J. Bone Miner. Metab.
, vol.19
, pp. 331-337
-
-
Orimo, H.1
Hayashi, Y.2
Fukunaga, M.3
Sone, T.4
Fujiwara, M.5
Shiraki, M.6
-
20
-
-
10744221715
-
Association of molecular variants, haplotypes, and linkage disequilibrium within the human vitamin D-binding protein (DBP) gene with postmenopausal bone mineral density
-
Ezura Y., Nakajima T., Kajita M., Ishida R., Inoue S., Yoshida H., et al. Association of molecular variants, haplotypes, and linkage disequilibrium within the human vitamin D-binding protein (DBP) gene with postmenopausal bone mineral density. J. Bone Miner. Res. 18 (2003) 1642-1649
-
(2003)
J. Bone Miner. Res.
, vol.18
, pp. 1642-1649
-
-
Ezura, Y.1
Nakajima, T.2
Kajita, M.3
Ishida, R.4
Inoue, S.5
Yoshida, H.6
-
21
-
-
0037292521
-
Association of a Trp16Ser variation in the gonadotropin releasing hormone (GnRH) signal peptide with bone mineral density, revealed by SNP-dependent PCR (Sd-PCR) typing
-
Iwasaki H., Emi M., Ezura Y., Ishida R., Kajita M., Kodaira M., et al. Association of a Trp16Ser variation in the gonadotropin releasing hormone (GnRH) signal peptide with bone mineral density, revealed by SNP-dependent PCR (Sd-PCR) typing. Bone 32 (2002) 185-190
-
(2002)
Bone
, vol.32
, pp. 185-190
-
-
Iwasaki, H.1
Emi, M.2
Ezura, Y.3
Ishida, R.4
Kajita, M.5
Kodaira, M.6
-
22
-
-
0034673547
-
Association of estrogen receptor b gene polymorphism with bone mineral density
-
Ogawa S., Hosoi T., Shiraki M., Orimo H., Emi M., Muramatsu M., et al. Association of estrogen receptor b gene polymorphism with bone mineral density. Biochem. Biophys. Res. Commun. 269 (2000) 537-541
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.269
, pp. 537-541
-
-
Ogawa, S.1
Hosoi, T.2
Shiraki, M.3
Orimo, H.4
Emi, M.5
Muramatsu, M.6
-
23
-
-
17544401107
-
Seven novel sequence variations in the human low density lipoprotein receptor related protein 5 (LRP5) gene
-
Okubo M., Horinishi A., Kim D.H., Yamamoto T.T., and Murase T. Seven novel sequence variations in the human low density lipoprotein receptor related protein 5 (LRP5) gene. Hum. Mutat. 19 (2002) 186
-
(2002)
Hum. Mutat.
, vol.19
, pp. 186
-
-
Okubo, M.1
Horinishi, A.2
Kim, D.H.3
Yamamoto, T.T.4
Murase, T.5
-
24
-
-
17344387757
-
Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation
-
Mein C.A., Barratt B.J., Dunn M.G., Siegmund T., Smith A.N., Esposito L., et al. Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation. Genome Res. 10 (2000) 330-343
-
(2000)
Genome Res.
, vol.10
, pp. 330-343
-
-
Mein, C.A.1
Barratt, B.J.2
Dunn, M.G.3
Siegmund, T.4
Smith, A.N.5
Esposito, L.6
-
25
-
-
0036956227
-
Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190 562 genetic variations in the human genome
-
Haga H., Yamada R., Ohnishi Y., Nakamura Y., and Tanaka T. Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190 562 genetic variations in the human genome. J. Hum. Genet. 47 (2002) 605-610
-
(2002)
J. Hum. Genet.
, vol.47
, pp. 605-610
-
-
Haga, H.1
Yamada, R.2
Ohnishi, Y.3
Nakamura, Y.4
Tanaka, T.5
-
26
-
-
0033930144
-
Juxtaposed regions of extensive minimal linkage disequilibrium in human Xq25 and Xq28
-
Miller P.T., Sardina I.B., Saccone N.L., Putzel J., Laitinen T., Cao A., et al. Juxtaposed regions of extensive minimal linkage disequilibrium in human Xq25 and Xq28. Nat. Genet. 25 (2000) 324-328
-
(2000)
Nat. Genet.
, vol.25
, pp. 324-328
-
-
Miller, P.T.1
Sardina, I.B.2
Saccone, N.L.3
Putzel, J.4
Laitinen, T.5
Cao, A.6
-
27
-
-
0023915850
-
The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes
-
Thompson E.A., Deeb S., Walker D., and Motulsky A.G. The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes. Am. J. Hum. Genet. 42 (1988) 113-124
-
(1988)
Am. J. Hum. Genet.
, vol.42
, pp. 113-124
-
-
Thompson, E.A.1
Deeb, S.2
Walker, D.3
Motulsky, A.G.4
-
28
-
-
0036119504
-
Accounting for human polymorphisms predicted to affect protein function
-
Ng P.C., and Henikoff S. Accounting for human polymorphisms predicted to affect protein function. Genome Res. 12 (2002) 436-446
-
(2002)
Genome Res.
, vol.12
, pp. 436-446
-
-
Ng, P.C.1
Henikoff, S.2
-
29
-
-
14844298409
-
Influence of LRP5 polymorphisms on normal variation in BMD
-
Koay M.A., Woon P.Y., Zhang Y., Miles L.J., Duncan E.L., Ralston S.H., et al. Influence of LRP5 polymorphisms on normal variation in BMD. J. Bone Miner. Res. 19 (2004) 1619-1627
-
(2004)
J. Bone Miner. Res.
, vol.19
, pp. 1619-1627
-
-
Koay, M.A.1
Woon, P.Y.2
Zhang, Y.3
Miles, L.J.4
Duncan, E.L.5
Ralston, S.H.6
-
30
-
-
14844326069
-
Contribution of the LRP5 gene to normal variation in peak BMD in women
-
Koller D.L., Ichikawa S., Johnson M.L., Lai D., Xuei X., Edenberg H.J., et al. Contribution of the LRP5 gene to normal variation in peak BMD in women. J. Bone Miner. Res. 20 (2005) 75-80
-
(2005)
J. Bone Miner. Res.
, vol.20
, pp. 75-80
-
-
Koller, D.L.1
Ichikawa, S.2
Johnson, M.L.3
Lai, D.4
Xuei, X.5
Edenberg, H.J.6
-
31
-
-
10744224854
-
High bone mass in mice expressing a mutant LRP5 gene
-
Babij P., Zhao W., Small C., Kharode Y., Yaworsky P.J., Bouxsein M.L., et al. High bone mass in mice expressing a mutant LRP5 gene. J. Bone Miner. Res. 18 (2003) 960-974
-
(2003)
J. Bone Miner. Res.
, vol.18
, pp. 960-974
-
-
Babij, P.1
Zhao, W.2
Small, C.3
Kharode, Y.4
Yaworsky, P.J.5
Bouxsein, M.L.6
-
32
-
-
0033305396
-
Genetics of osteoporosis
-
Eisman J.A. Genetics of osteoporosis. Endocr. Rev. 20 (1999) 788-804
-
(1999)
Endocr. Rev.
, vol.20
, pp. 788-804
-
-
Eisman, J.A.1
-
34
-
-
0035134345
-
Role of genetic factors in the pathophysiology and management of osteoporosis
-
Hobson E.E., and Ralston S.H. Role of genetic factors in the pathophysiology and management of osteoporosis. Clin. Endocrinol. 54 (2001) 1-9
-
(2001)
Clin. Endocrinol.
, vol.54
, pp. 1-9
-
-
Hobson, E.E.1
Ralston, S.H.2
-
35
-
-
0033678444
-
Genome screen for QTLs contributing to normal variation in bone mineral density and osteoporosis
-
Koller D.L., Econs M.J., Morin P.A., Christian J.C., Hui S.L., Parry P., et al. Genome screen for QTLs contributing to normal variation in bone mineral density and osteoporosis. J. Clin. Endocrinol. Metab. 85 (2000) 3116-3120
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 3116-3120
-
-
Koller, D.L.1
Econs, M.J.2
Morin, P.A.3
Christian, J.C.4
Hui, S.L.5
Parry, P.6
-
36
-
-
0036861322
-
Relationships among body mass, its components, and bone
-
Reid I.R. Relationships among body mass, its components, and bone. Bone 31 (2002) 547-555
-
(2002)
Bone
, vol.31
, pp. 547-555
-
-
Reid, I.R.1
-
37
-
-
0033773314
-
A neuro(endo)crine regulation of bone remodeling
-
Amling M., Takeda S., and Karsenty G. A neuro(endo)crine regulation of bone remodeling. BioEssays 22 (2000) 970-975
-
(2000)
BioEssays
, vol.22
, pp. 970-975
-
-
Amling, M.1
Takeda, S.2
Karsenty, G.3
-
39
-
-
0036847619
-
Leptin regulates bone formation via the sympathetic nervous system
-
Takeda S., Elefteriou F., Levasseur R., Liu X., Zhao L., Parker K.L., et al. Leptin regulates bone formation via the sympathetic nervous system. Cell 111 (2002) 305-3017
-
(2002)
Cell
, vol.111
, pp. 305-3017
-
-
Takeda, S.1
Elefteriou, F.2
Levasseur, R.3
Liu, X.4
Zhao, L.5
Parker, K.L.6
-
40
-
-
0030846737
-
Association of bone mineral density with apolipoprotein E phenotype
-
Shiraki M., Shiraki Y., Aoki C., Hosoi T., Inoue S., Kaneki M., et al. Association of bone mineral density with apolipoprotein E phenotype. J. Bone Miner. Res. 12 (1997) 1438-1445
-
(1997)
J. Bone Miner. Res.
, vol.12
, pp. 1438-1445
-
-
Shiraki, M.1
Shiraki, Y.2
Aoki, C.3
Hosoi, T.4
Inoue, S.5
Kaneki, M.6
-
41
-
-
0036090467
-
Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation
-
Lecka-Czernik B., Moerman E.J., Grant D.F., Lehmann J.M., Manolagas S.C., and Jilka R.L. Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation. Endocrinology 143 (2002) 2376-2384
-
(2002)
Endocrinology
, vol.143
, pp. 2376-2384
-
-
Lecka-Czernik, B.1
Moerman, E.J.2
Grant, D.F.3
Lehmann, J.M.4
Manolagas, S.C.5
Jilka, R.L.6
|