메뉴 건너뛰기




Volumn 10, Issue 8, 2010, Pages 1070-1082

Translational errors: From yeast to new therapeutic targets

Author keywords

Aminoglycosides; Frameshifting; Genetic diseases; HIV 1; Stop codon readthrough; Yeast

Indexed keywords

EFAVIRENZ; ENFUVIRTIDE; INDINAVIR; MARAVIROC; MESSENGER RNA; RALTEGRAVIR; TRANSFER RNA; TRANSLATION TERMINATION FACTOR; VIRUS RNA; ZIDOVUDINE;

EID: 78349241066     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1111/j.1567-1364.2010.00684.x     Document Type: Review
Times cited : (16)

References (118)
  • 1
    • 39449127401 scopus 로고    scopus 로고
    • Drug-induced readthrough of premature stop codons leads to the stabilization of laminin alpha2 chain mRNA in CMD myotubes
    • Allamand V, Bidou L, Arakawa M et al. (2008) Drug-induced readthrough of premature stop codons leads to the stabilization of laminin alpha2 chain mRNA in CMD myotubes. J Gene Med 10: 217-224.
    • (2008) J Gene Med , vol.10 , pp. 217-224
    • Allamand, V.1    Bidou, L.2    Arakawa, M.3
  • 2
    • 33750989874 scopus 로고    scopus 로고
    • Selenoprotein synthesis
    • &, Biochimie
    • Allmang C & Krol A (2006) Selenoprotein synthesis: UGA does not end the story. Biochimie 88: 1561-1571.
    • (2006) UGA does not end the story , vol.88 , pp. 1561-1571
    • Allmang, C.1    Krol, A.2
  • 3
    • 0347993773 scopus 로고    scopus 로고
    • Negamycin restores dystrophin expression in skeletal and cardiac muscles of mdx mice
    • Arakawa M, Shiozuka M, Nakayama Y et al. (2003) Negamycin restores dystrophin expression in skeletal and cardiac muscles of mdx mice. J Biochem 134: 751-758.
    • (2003) J Biochem , vol.134 , pp. 751-758
    • Arakawa, M.1    Shiozuka, M.2    Nakayama, Y.3
  • 4
    • 15644379785 scopus 로고    scopus 로고
    • Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae
    • Asakura T, Sasaki T, Nagano F et al. (1998) Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae. Oncogene 16: 121-130.
    • (1998) Oncogene , vol.16 , pp. 121-130
    • Asakura, T.1    Sasaki, T.2    Nagano, F.3
  • 6
    • 62549134976 scopus 로고    scopus 로고
    • Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression
    • Auld DS, Thorne N, Maguire WF & Inglese J (2009) Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression. P Natl Acad Sci USA 106: 3585-3590.
    • (2009) P Natl Acad Sci USA , vol.106 , pp. 3585-3590
    • Auld, D.S.1    Thorne, N.2    Maguire, W.F.3    Inglese, J.4
  • 7
    • 77950430317 scopus 로고    scopus 로고
    • Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124
    • Auld DS, Lovell S, Thorne N et al. (2010) Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124. P Natl Acad Sci USA 107: 4878-4883.
    • (2010) P Natl Acad Sci USA , vol.107 , pp. 4878-4883
    • Auld, D.S.1    Lovell, S.2    Thorne, N.3
  • 8
    • 0034650834 scopus 로고    scopus 로고
    • Inhibition of in vitro and ex vivo translation by a transplatin-modified oligo(2'-O-methylribonucleotide) directed against the HIV-1 gag-pol frameshift signal
    • Aupeix-Scheidler K, Chabas S, Bidou L, Rousset JP, Leng M & Toulme JJ (2000) Inhibition of in vitro and ex vivo translation by a transplatin-modified oligo(2'-O-methylribonucleotide) directed against the HIV-1 gag-pol frameshift signal. Nucleic Acids Res 28: 438-445.
    • (2000) Nucleic Acids Res , vol.28 , pp. 438-445
    • Aupeix-Scheidler, K.1    Chabas, S.2    Bidou, L.3    Rousset, J.P.4    Leng, M.5    Toulme, J.J.6
  • 9
    • 10744225913 scopus 로고    scopus 로고
    • Isolation of drugs active against mammalian prions using a yeast-based screening assay
    • Bach S, Talarek N, Andrieu T et al. (2003) Isolation of drugs active against mammalian prions using a yeast-based screening assay. Nat Biotechnol 21: 1075-1081.
    • (2003) Nat Biotechnol , vol.21 , pp. 1075-1081
    • Bach, S.1    Talarek, N.2    Andrieu, T.3
  • 13
    • 0141631892 scopus 로고    scopus 로고
    • Efficiency of a programmed -1 ribosomal frameshift in the different subtypes of the human immunodeficiency virus type 1 group M
    • Baril M, Dulude D, Gendron K, Lemay G & Brakier-Gingras L (2003) Efficiency of a programmed -1 ribosomal frameshift in the different subtypes of the human immunodeficiency virus type 1 group M. RNA 9: 1246-1253.
    • (2003) RNA , vol.9 , pp. 1246-1253
    • Baril, M.1    Dulude, D.2    Gendron, K.3    Lemay, G.4    Brakier-Gingras, L.5
  • 14
    • 0018577407 scopus 로고
    • A different genetic code in human mitochondria
    • Barrell BG, Bankier AT & Drouin J (1979) A different genetic code in human mitochondria. Nature 282: 189-194.
    • (1979) Nature , vol.282 , pp. 189-194
    • Barrell, B.G.1    Bankier, A.T.2    Drouin, J.3
  • 16
    • 0030702773 scopus 로고    scopus 로고
    • Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line
    • Bedwell DM, Kaenjak A, Benos DJ et al. (1997) Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line. Nat Med 3: 1280-1284.
    • (1997) Nat Med , vol.3 , pp. 1280-1284
    • Bedwell, D.M.1    Kaenjak, A.2    Benos, D.J.3
  • 17
    • 0036203203 scopus 로고    scopus 로고
    • Influence of the stacking potential of the base 3' of tandem shift codons on -1 ribosomal frameshifting used for gene expression
    • Bertrand C, Prere MF, Gesteland RF, Atkins JF & Fayet O (2002) Influence of the stacking potential of the base 3' of tandem shift codons on -1 ribosomal frameshifting used for gene expression. RNA 8: 16-28.
    • (2002) RNA , vol.8 , pp. 16-28
    • Bertrand, C.1    Prere, M.F.2    Gesteland, R.F.3    Atkins, J.F.4    Fayet, O.5
  • 18
    • 0030880945 scopus 로고    scopus 로고
    • In vivo HIV-1 frameshifting efficiency is directly related to the stability of the stem-loop stimulatory signal
    • Bidou L, Stahl G, Grima B, Liu H, Cassan M & Rousset JP (1997) In vivo HIV-1 frameshifting efficiency is directly related to the stability of the stem-loop stimulatory signal. RNA 3: 1153-1158.
    • (1997) RNA , vol.3 , pp. 1153-1158
    • Bidou, L.1    Stahl, G.2    Grima, B.3    Liu, H.4    Cassan, M.5    Rousset, J.P.6
  • 19
    • 0033942924 scopus 로고    scopus 로고
    • Nonsense-mediated decay mutants do not affect programmed -1 frameshifting
    • Bidou L, Stahl G, Hatin I, Namy O, Rousset JP & Farabaugh PJ (2000) Nonsense-mediated decay mutants do not affect programmed -1 frameshifting. RNA 6: 952-961.
    • (2000) RNA , vol.6 , pp. 952-961
    • Bidou, L.1    Stahl, G.2    Hatin, I.3    Namy, O.4    Rousset, J.P.5    Farabaugh, P.J.6
  • 20
    • 1842586020 scopus 로고    scopus 로고
    • Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment
    • Bidou L, Hatin I, Perez N, Allamand V, Panthier JJ & Rousset JP (2004) Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment. Gene Ther 11: 619-627.
    • (2004) Gene Ther , vol.11 , pp. 619-627
    • Bidou, L.1    Hatin, I.2    Perez, N.3    Allamand, V.4    Panthier, J.J.5    Rousset, J.P.6
  • 21
    • 0025354943 scopus 로고
    • Programmed ribosomal frameshifting generates the Escherichia coli DNA polymerase III gamma subunit from within the tau subunit reading frame
    • Blinkowa AL & Walker JR (1990) Programmed ribosomal frameshifting generates the Escherichia coli DNA polymerase III gamma subunit from within the tau subunit reading frame. Nucleic Acids Res 18: 1725-1729.
    • (1990) Nucleic Acids Res , vol.18 , pp. 1725-1729
    • Blinkowa, A.L.1    Walker, J.R.2
  • 22
    • 0029153552 scopus 로고
    • The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae
    • Bonetti B, Fu L, Moon J & Bedwell DM (1995) The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae. J Mol Biol 251: 334-345.
    • (1995) J Mol Biol , vol.251 , pp. 334-345
    • Bonetti, B.1    Fu, L.2    Moon, J.3    Bedwell, D.M.4
  • 23
    • 33646779223 scopus 로고    scopus 로고
    • Programmed ribosomal frameshifting in HIV-1 and the SARS-CoV
    • Brierley I & Dos Ramos FJ (2006) Programmed ribosomal frameshifting in HIV-1 and the SARS-CoV. Virus Res 119: 29-42.
    • (2006) Virus Res , vol.119 , pp. 29-42
    • Brierley, I.1    Dos Ramos, F.J.2
  • 24
    • 0024411889 scopus 로고
    • Characterization of an efficient coronavirus ribosomal frameshifting signal
    • &, Cell
    • Brierley I, Digard P & Inglis SC (1989) Characterization of an efficient coronavirus ribosomal frameshifting signal: requirement for an RNA pseudoknot. Cell 57: 537-547.
    • (1989) requirement for an RNA pseudoknot , vol.57 , pp. 537-547
    • Brierley, I.1    Digard, P.2    Inglis, S.C.3
  • 25
    • 0025769767 scopus 로고
    • Mutational analysis of the RNA pseudoknot component of a coronavirus ribosomal frameshifting signal
    • Brierley I, Rolley NJ, Jenner AJ & Inglis SC (1991) Mutational analysis of the RNA pseudoknot component of a coronavirus ribosomal frameshifting signal. J Mol Biol 220: 889-902.
    • (1991) J Mol Biol , vol.220 , pp. 889-902
    • Brierley, I.1    Rolley, N.J.2    Jenner, A.J.3    Inglis, S.C.4
  • 26
    • 49349100603 scopus 로고    scopus 로고
    • RNA pseudoknots and the regulation of protein synthesis
    • Brierley I, Gilbert RJ & Pennell S (2008) RNA pseudoknots and the regulation of protein synthesis. Biochem Soc T 36: 684-689.
    • (2008) Biochem Soc T , vol.36 , pp. 684-689
    • Brierley, I.1    Gilbert, R.J.2    Pennell, S.3
  • 27
    • 0022423513 scopus 로고
    • Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromomycin
    • Burke JF & Mogg AE (1985) Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromomycin. Nucleic Acids Res 13: 6265-6272.
    • (1985) Nucleic Acids Res , vol.13 , pp. 6265-6272
    • Burke, J.F.1    Mogg, A.E.2
  • 30
    • 0028031976 scopus 로고
    • Translational frameshifting at the gag-pol junction of human immunodeficiency virus type 1 is not increased in infected T-lymphoid cells
    • Cassan M, Delaunay N, Vaquero C & Rousset JP (1994) Translational frameshifting at the gag-pol junction of human immunodeficiency virus type 1 is not increased in infected T-lymphoid cells. J Virol 68: 1501-1508.
    • (1994) J Virol , vol.68 , pp. 1501-1508
    • Cassan, M.1    Delaunay, N.2    Vaquero, C.3    Rousset, J.P.4
  • 31
    • 65449127059 scopus 로고    scopus 로고
    • Structural insights into eRF3 and stop codon recognition by eRF1
    • Cheng Z, Saito K, Pisarev AV et al. (2009) Structural insights into eRF3 and stop codon recognition by eRF1. Genes Dev 23: 1106-1118.
    • (2009) Genes Dev , vol.23 , pp. 1106-1118
    • Cheng, Z.1    Saito, K.2    Pisarev, A.V.3
  • 33
    • 38049129654 scopus 로고    scopus 로고
    • Mammalian gene PEG10 expresses two reading frames by high efficiency -1 frameshifting in embryonic-associated tissues
    • Clark MB, Janicke M, Gottesbuhren U, Kleffmann T, Legge M, Poole ES & Tate WP (2007) Mammalian gene PEG10 expresses two reading frames by high efficiency -1 frameshifting in embryonic-associated tissues. J Biol Chem 282: 37359-37369.
    • (2007) J Biol Chem , vol.282 , pp. 37359-37369
    • Clark, M.B.1    Janicke, M.2    Gottesbuhren, U.3    Kleffmann, T.4    Legge, M.5    Poole, E.S.6    Tate, W.P.7
  • 34
    • 0022547355 scopus 로고
    • Expression of peptide chain release factor 2 requires high-efficiency frameshift
    • Craigen WJ & Caskey CT (1986) Expression of peptide chain release factor 2 requires high-efficiency frameshift. Nature 322: 273-275.
    • (1986) Nature , vol.322 , pp. 273-275
    • Craigen, W.J.1    Caskey, C.T.2
  • 35
    • 0029854442 scopus 로고    scopus 로고
    • Mof4-1 is an allele of the UPF1/IFS2 gene which affects both mRNA turnover and -1 ribosomal frameshifting efficiency
    • Cui Y, Dinman JD & Peltz SW (1996) Mof4-1 is an allele of the UPF1/IFS2 gene which affects both mRNA turnover and -1 ribosomal frameshifting efficiency. EMBO J 15: 5726-5736.
    • (1996) EMBO J , vol.15 , pp. 5726-5736
    • Cui, Y.1    Dinman, J.D.2    Peltz, S.W.3
  • 36
    • 0028032017 scopus 로고
    • Translational maintenance of frame
    • Dinman JD & Wickner RB (1994) Translational maintenance of frame. Genetics 136: 75-86.
    • (1994) Genetics , vol.136 , pp. 75-86
    • Dinman, J.D.1    Wickner, R.B.2
  • 37
    • 10644251799 scopus 로고    scopus 로고
    • Programmed -1 ribosomal frameshifting in the SARS coronavirus
    • Dos Ramos F, Carrasco M, Doyle T & Brierley I (2004) Programmed -1 ribosomal frameshifting in the SARS coronavirus. Biochem Soc T 32: 1081-1083.
    • (2004) Biochem Soc T , vol.32 , pp. 1081-1083
    • Dos Ramos, F.1    Carrasco, M.2    Doyle, T.3    Brierley, I.4
  • 38
    • 0036924931 scopus 로고    scopus 로고
    • Characterization of the frameshift stimulatory signal controlling a programmed -1 ribosomal frameshift in the human immunodeficiency virus type 1
    • Dulude D, Baril M & Brakier-Gingras L (2002) Characterization of the frameshift stimulatory signal controlling a programmed -1 ribosomal frameshift in the human immunodeficiency virus type 1. Nucleic Acids Res 30: 5094-5102.
    • (2002) Nucleic Acids Res , vol.30 , pp. 5094-5102
    • Dulude, D.1    Baril, M.2    Brakier-Gingras, L.3
  • 39
    • 0032937983 scopus 로고    scopus 로고
    • The C-terminus of eRF1 defines a functionally important domain for translation termination in Saccharomyces cerevisiae
    • Eurwilaichitr L, Graves FM, Stansfield I & Tuite MF (1999) The C-terminus of eRF1 defines a functionally important domain for translation termination in Saccharomyces cerevisiae. Mol Microbiol 32: 485-496.
    • (1999) Mol Microbiol , vol.32 , pp. 485-496
    • Eurwilaichitr, L.1    Graves, F.M.2    Stansfield, I.3    Tuite, M.F.4
  • 40
    • 38049092550 scopus 로고    scopus 로고
    • Eukaryotic ribosomal RNA determinants of aminoglycoside resistance and their role in translational fidelity
    • Fan-Minogue H & Bedwell DM (2008) Eukaryotic ribosomal RNA determinants of aminoglycoside resistance and their role in translational fidelity. RNA 14: 148-157.
    • (2008) RNA , vol.14 , pp. 148-157
    • Fan-Minogue, H.1    Bedwell, D.M.2
  • 41
    • 0028242356 scopus 로고
    • Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family
    • Fearon K, McClendon V, Bonetti B & Bedwell DM (1994) Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family. J Biol Chem 269: 17802-17808.
    • (1994) J Biol Chem , vol.269 , pp. 17802-17808
    • Fearon, K.1    McClendon, V.2    Bonetti, B.3    Bedwell, D.M.4
  • 42
    • 75849156881 scopus 로고    scopus 로고
    • Direct observation of distinct A/P hybrid-state tRNAs in translocating ribosomes
    • Flanagan JF, Namy O, Brierley I & Gilbert RJ (2010) Direct observation of distinct A/P hybrid-state tRNAs in translocating ribosomes. Structure 18: 257-264.
    • (2010) Structure , vol.18 , pp. 257-264
    • Flanagan, J.F.1    Namy, O.2    Brierley, I.3    Gilbert, R.J.4
  • 43
    • 0025303309 scopus 로고
    • The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting
    • Flower AM & McHenry CS (1990) The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting. P Natl Acad Sci USA 87: 3713-3717.
    • (1990) P Natl Acad Sci USA , vol.87 , pp. 3713-3717
    • Flower, A.M.1    McHenry, C.S.2
  • 44
    • 0028581973 scopus 로고
    • A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor
    • Frolova L, Le Goff X, Rasmussen HH et al. (1994) A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor. Nature 372: 701-703.
    • (1994) Nature , vol.372 , pp. 701-703
    • Frolova, L.1    Le Goff, X.2    Rasmussen, H.H.3
  • 45
    • 0036216442 scopus 로고    scopus 로고
    • Highly conserved NIKS tetrapeptide is functionally essential in eukaryotic translation termination factor eRF1
    • Frolova L, Seit-Nebi A & Kisselev L (2002) Highly conserved NIKS tetrapeptide is functionally essential in eukaryotic translation termination factor eRF1. RNA 8: 129-136.
    • (2002) RNA , vol.8 , pp. 129-136
    • Frolova, L.1    Seit-Nebi, A.2    Kisselev, L.3
  • 47
    • 0034724565 scopus 로고    scopus 로고
    • Structure, stability and function of RNA pseudoknots involved in stimulating ribosomal frameshifting
    • Giedroc DP, Theimer CA & Nixon PL (2000) Structure, stability and function of RNA pseudoknots involved in stimulating ribosomal frameshifting. J Mol Biol 298: 167-185.
    • (2000) J Mol Biol , vol.298 , pp. 167-185
    • Giedroc, D.P.1    Theimer, C.A.2    Nixon, P.L.3
  • 48
    • 33846143163 scopus 로고    scopus 로고
    • Structure-function analysis of the ribosomal frameshifting signal of two human immunodeficiency virus type 1 isolates with increased resistance to viral protease inhibitors
    • Girnary R, King L, Robinson L, Elston R & Brierley I (2007) Structure-function analysis of the ribosomal frameshifting signal of two human immunodeficiency virus type 1 isolates with increased resistance to viral protease inhibitors. J Gen Virol 88: 226-235.
    • (2007) J Gen Virol , vol.88 , pp. 226-235
    • Girnary, R.1    King, L.2    Robinson, L.3    Elston, R.4    Brierley, I.5
  • 51
    • 0036342198 scopus 로고    scopus 로고
    • The structures of four macrolide antibiotics bound to the large ribosomal subunit
    • Hansen JL, Ippolito JA, Ban N, Nissen P, Moore PB & Steitz TA (2002) The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol Cell 10: 117-128.
    • (2002) Mol Cell , vol.10 , pp. 117-128
    • Hansen, J.L.1    Ippolito, J.A.2    Ban, N.3    Nissen, P.4    Moore, P.B.5    Steitz, T.A.6
  • 52
    • 7044260452 scopus 로고    scopus 로고
    • Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough
    • Harger JW & Dinman JD (2004) Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough. RNA 10: 1721-1729.
    • (2004) RNA , vol.10 , pp. 1721-1729
    • Harger, J.W.1    Dinman, J.D.2
  • 53
    • 0031901133 scopus 로고    scopus 로고
    • Importance of ribosomal frameshifting for human immunodeficiency virus type 1 particle assembly and replication
    • Hung M, Patel P, Davis S & Green SR (1998) Importance of ribosomal frameshifting for human immunodeficiency virus type 1 particle assembly and replication. J Virol 72: 4819-4824.
    • (1998) J Virol , vol.72 , pp. 4819-4824
    • Hung, M.1    Patel, P.2    Davis, S.3    Green, S.R.4
  • 54
    • 0024277965 scopus 로고
    • Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region
    • Jacks T, Madhani HD, Masiarz FR & Varmus HE (1988) Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region. Cell 55: 447-458.
    • (1988) Cell , vol.55 , pp. 447-458
    • Jacks, T.1    Madhani, H.D.2    Masiarz, F.R.3    Varmus, H.E.4
  • 55
    • 0021341393 scopus 로고
    • Aminoglycoside toxicity - a review of clinical studies published between 1975 and 1982
    • Kahlmeter G & Dahlager JI (1984) Aminoglycoside toxicity - a review of clinical studies published between 1975 and 1982. J Antimicrob Chemoth 13 (suppl A): 9-22.
    • (1984) J Antimicrob Chemoth , vol.13 , Issue.SUPPL A , pp. 9-22
    • Kahlmeter, G.1    Dahlager, J.I.2
  • 56
    • 0032721006 scopus 로고    scopus 로고
    • Correction of genetic disease by making sense from nonsense
    • Kaufman RJ (1999) Correction of genetic disease by making sense from nonsense. J Clin Invest 104: 367-368.
    • (1999) J Clin Invest , vol.104 , pp. 367-368
    • Kaufman, R.J.1
  • 57
    • 0029671218 scopus 로고    scopus 로고
    • Trans-acting proteins involved in RNA encapsidation and viral assembly in human immunodeficiency virus type 1
    • Kaye JF & Lever AM (1996) Trans-acting proteins involved in RNA encapsidation and viral assembly in human immunodeficiency virus type 1. J Virol 70: 880-886.
    • (1996) J Virol , vol.70 , pp. 880-886
    • Kaye, J.F.1    Lever, A.M.2
  • 58
    • 0035997219 scopus 로고    scopus 로고
    • Clinically relevant aminoglycosides can suppress disease-associated premature stop mutations in the IDUA and P53 cDNAs in a mammalian translation system
    • Keeling KM & Bedwell DM (2002) Clinically relevant aminoglycosides can suppress disease-associated premature stop mutations in the IDUA and P53 cDNAs in a mammalian translation system. J Mol Med 80: 367-376.
    • (2002) J Mol Med , vol.80 , pp. 367-376
    • Keeling, K.M.1    Bedwell, D.M.2
  • 59
    • 0027941188 scopus 로고
    • The sequences of and distance between two cis-acting signals determine the efficiency of ribosomal frameshifting in human immunodeficiency virus type 1 and human T-cell leukemia virus type II in vivo
    • Kollmus H, Honigman A, Panet A & Hauser H (1994) The sequences of and distance between two cis-acting signals determine the efficiency of ribosomal frameshifting in human immunodeficiency virus type 1 and human T-cell leukemia virus type II in vivo. J Virol 68: 6087-6091.
    • (1994) J Virol , vol.68 , pp. 6087-6091
    • Kollmus, H.1    Honigman, A.2    Panet, A.3    Hauser, H.4
  • 60
    • 0035200990 scopus 로고    scopus 로고
    • Ribosomal pausing at a frameshifter RNA pseudoknot is sensitive to reading phase but shows little correlation with frameshift efficiency
    • Kontos H, Napthine S & Brierley I (2001) Ribosomal pausing at a frameshifter RNA pseudoknot is sensitive to reading phase but shows little correlation with frameshift efficiency. Mol Cell Biol 21: 8657-8670.
    • (2001) Mol Cell Biol , vol.21 , pp. 8657-8670
    • Kontos, H.1    Napthine, S.2    Brierley, I.3
  • 61
    • 33845895536 scopus 로고    scopus 로고
    • The frequency of translational misreading errors in E. coli is largely determined by tRNA competition
    • Kramer EB & Farabaugh PJ (2007) The frequency of translational misreading errors in E. coli is largely determined by tRNA competition. RNA 13: 87-96.
    • (2007) RNA , vol.13 , pp. 87-96
    • Kramer, E.B.1    Farabaugh, P.J.2
  • 62
    • 0029014536 scopus 로고
    • A genetic screen identifies cellular factors involved in retroviral -1 frameshifting
    • Lee SI, Umen JG & Varmus HE (1995) A genetic screen identifies cellular factors involved in retroviral -1 frameshifting. P Natl Acad Sci USA 92: 6587-6591.
    • (1995) P Natl Acad Sci USA , vol.92 , pp. 6587-6591
    • Lee, S.I.1    Umen, J.G.2    Varmus, H.E.3
  • 63
    • 34548768192 scopus 로고    scopus 로고
    • The three transfer RNAs occupying the A, P and E sites on the ribosome are involved in viral programmed -1 ribosomal frameshift
    • Leger M, Dulude D, Steinberg SV & Brakier-Gingras L (2007) The three transfer RNAs occupying the A, P and E sites on the ribosome are involved in viral programmed -1 ribosomal frameshift. Nucleic Acids Res 35: 5581-5592.
    • (2007) Nucleic Acids Res , vol.35 , pp. 5581-5592
    • Leger, M.1    Dulude, D.2    Steinberg, S.V.3    Brakier-Gingras, L.4
  • 64
    • 0023907071 scopus 로고
    • Gene for a novel tRNA species that accepts l-serine and cotranslationally inserts selenocysteine
    • Leinfelder W, Zehelein E, Mandrand-Berthelot MA & Bock A (1988) Gene for a novel tRNA species that accepts l-serine and cotranslationally inserts selenocysteine. Nature 331: 723-725.
    • (1988) Nature , vol.331 , pp. 723-725
    • Leinfelder, W.1    Zehelein, E.2    Mandrand-Berthelot, M.A.3    Bock, A.4
  • 65
    • 0033984933 scopus 로고    scopus 로고
    • Kinetics of ribosomal pausing during programmed -1 translational frameshifting
    • Lopinski JD, Dinman JD & Bruenn JA (2000) Kinetics of ribosomal pausing during programmed -1 translational frameshifting. Mol Cell Biol 20: 1095-1103.
    • (2000) Mol Cell Biol , vol.20 , pp. 1095-1103
    • Lopinski, J.D.1    Dinman, J.D.2    Bruenn, J.A.3
  • 66
    • 15044348272 scopus 로고    scopus 로고
    • Characterization of the frameshift signal of Edr, a mammalian example of programmed -1 ribosomal frameshifting
    • Manktelow E, Shigemoto K & Brierley I (2005) Characterization of the frameshift signal of Edr, a mammalian example of programmed -1 ribosomal frameshifting. Nucleic Acids Res 33: 1553-1563.
    • (2005) Nucleic Acids Res , vol.33 , pp. 1553-1563
    • Manktelow, E.1    Shigemoto, K.2    Brierley, I.3
  • 67
    • 0033929810 scopus 로고    scopus 로고
    • Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system
    • Manuvakhova M, Keeling K & Bedwell DM (2000) Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system. RNA 6: 1044-1055.
    • (2000) RNA , vol.6 , pp. 1044-1055
    • Manuvakhova, M.1    Keeling, K.2    Bedwell, D.M.3
  • 68
    • 0032573606 scopus 로고    scopus 로고
    • Secondary structure and mutational analysis of the ribosomal frameshift signal of rous sarcoma virus
    • Marczinke B, Fisher R, Vidakovic M, Bloys AJ & Brierley I (1998) Secondary structure and mutational analysis of the ribosomal frameshift signal of rous sarcoma virus. J Mol Biol 284: 205-225.
    • (1998) J Mol Biol , vol.284 , pp. 205-225
    • Marczinke, B.1    Fisher, R.2    Vidakovic, M.3    Bloys, A.J.4    Brierley, I.5
  • 73
    • 0031474466 scopus 로고    scopus 로고
    • Programmed translational frameshifting in a gene required for yeast telomere replication
    • Morris DK & Lundblad V (1997) Programmed translational frameshifting in a gene required for yeast telomere replication. Curr Biol 7: 969-976.
    • (1997) Curr Biol , vol.7 , pp. 969-976
    • Morris, D.K.1    Lundblad, V.2
  • 74
    • 0034779875 scopus 로고    scopus 로고
    • Impact of the six nucleotides downstream of the stop codon on translation termination
    • Namy O, Hatin I & Rousset JP (2001) Impact of the six nucleotides downstream of the stop codon on translation termination. EMBO Rep 2: 787-793.
    • (2001) EMBO Rep , vol.2 , pp. 787-793
    • Namy, O.1    Hatin, I.2    Rousset, J.P.3
  • 76
    • 0842267214 scopus 로고    scopus 로고
    • Reprogrammed genetic decoding in cellular gene expression
    • Namy O, Rousset JP, Napthine S & Brierley I (2004) Reprogrammed genetic decoding in cellular gene expression. Mol Cell 13: 157-168.
    • (2004) Mol Cell , vol.13 , pp. 157-168
    • Namy, O.1    Rousset, J.P.2    Napthine, S.3    Brierley, I.4
  • 77
    • 33646557329 scopus 로고    scopus 로고
    • A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting
    • Namy O, Moran SJ, Stuart DI, Gilbert RJ & Brierley I (2006) A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting. Nature 441: 244-247.
    • (2006) Nature , vol.441 , pp. 244-247
    • Namy, O.1    Moran, S.J.2    Stuart, D.I.3    Gilbert, R.J.4    Brierley, I.5
  • 78
    • 35548939370 scopus 로고    scopus 로고
    • Adding pyrrolysine to the Escherichia coli genetic code
    • Namy O, Zhou Y, Gundllapalli S et al. (2007) Adding pyrrolysine to the Escherichia coli genetic code. FEBS Lett 581: 5282-5288.
    • (2007) FEBS Lett , vol.581 , pp. 5282-5288
    • Namy, O.1    Zhou, Y.2    Gundllapalli, S.3
  • 80
    • 0033532080 scopus 로고    scopus 로고
    • The role of RNA pseudoknot stem 1 length in the promotion of efficient -1 ribosomal frameshifting
    • Napthine S, Liphardt J, Bloys A, Routledge S & Brierley I (1999) The role of RNA pseudoknot stem 1 length in the promotion of efficient -1 ribosomal frameshifting. J Mol Biol 288: 305-320.
    • (1999) J Mol Biol , vol.288 , pp. 305-320
    • Napthine, S.1    Liphardt, J.2    Bloys, A.3    Routledge, S.4    Brierley, I.5
  • 81
    • 33845951105 scopus 로고    scopus 로고
    • Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance
    • Ortiz PA, Ulloque R, Kihara GK, Zheng H & Kinzy TG (2006) Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance. J Biol Chem 281: 32639-32648.
    • (2006) J Biol Chem , vol.281 , pp. 32639-32648
    • Ortiz, P.A.1    Ulloque, R.2    Kihara, G.K.3    Zheng, H.4    Kinzy, T.G.5
  • 82
    • 0018790866 scopus 로고
    • Variation of phenotypic suppression due to the psi+ and psi- extrachromosomal determinants in yeast
    • Palmer E, Wilhelm JM & Sherman F (1979) Variation of phenotypic suppression due to the psi+ and psi- extrachromosomal determinants in yeast. J Mol Biol 128: 107-110.
    • (1979) J Mol Biol , vol.128 , pp. 107-110
    • Palmer, E.1    Wilhelm, J.M.2    Sherman, F.3
  • 83
    • 0033961143 scopus 로고    scopus 로고
    • Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome
    • Pape T, Wintermeyer W & Rodnina MV (2000) Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome. Nat Struct Biol 7: 104-107.
    • (2000) Nat Struct Biol , vol.7 , pp. 104-107
    • Pape, T.1    Wintermeyer, W.2    Rodnina, M.V.3
  • 84
    • 0032931260 scopus 로고    scopus 로고
    • Ribosomal protein L3 mutants alter translational fidelity and promote rapid loss of the yeast killer virus
    • Peltz SW, Hammell AB, Cui Y, Yasenchak J, Puljanowski L & Dinman JD (1999) Ribosomal protein L3 mutants alter translational fidelity and promote rapid loss of the yeast killer virus. Mol Cell Biol 19: 384-391.
    • (1999) Mol Cell Biol , vol.19 , pp. 384-391
    • Peltz, S.W.1    Hammell, A.B.2    Cui, Y.3    Yasenchak, J.4    Puljanowski, L.5    Dinman, J.D.6
  • 86
    • 45749109340 scopus 로고    scopus 로고
    • The stimulatory RNA of the Visna-Maedi retrovirus ribosomal frameshifting signal is an unusual pseudoknot with an interstem element
    • Pennell S, Manktelow E, Flatt A, Kelly G, Smerdon SJ & Brierley I (2008) The stimulatory RNA of the Visna-Maedi retrovirus ribosomal frameshifting signal is an unusual pseudoknot with an interstem element. RNA 14: 1366-1377.
    • (2008) RNA , vol.14 , pp. 1366-1377
    • Pennell, S.1    Manktelow, E.2    Flatt, A.3    Kelly, G.4    Smerdon, S.J.5    Brierley, I.6
  • 89
    • 1342327618 scopus 로고    scopus 로고
    • A programmed -1 ribosomal frameshift signal can function as a cis-acting mRNA destabilizing element
    • Plant EP, Wang P, Jacobs JL & Dinman JD (2004) A programmed -1 ribosomal frameshift signal can function as a cis-acting mRNA destabilizing element. Nucleic Acids Res 32: 784-790.
    • (2004) Nucleic Acids Res , vol.32 , pp. 784-790
    • Plant, E.P.1    Wang, P.2    Jacobs, J.L.3    Dinman, J.D.4
  • 90
  • 91
    • 77950837290 scopus 로고    scopus 로고
    • Restoration of APC gene function in colorectal cancer cells by aminoglycoside- and macrolide-induced read-through of premature termination codons
    • Rosin-Arbesfeld R, Zilberberg A & Lahav L (2009) Restoration of APC gene function in colorectal cancer cells by aminoglycoside- and macrolide-induced read-through of premature termination codons. Gut 59: 496-507.
    • (2009) Gut , vol.59 , pp. 496-507
    • Rosin-Arbesfeld, R.1    Zilberberg, A.2    Lahav, L.3
  • 92
    • 68649089108 scopus 로고    scopus 로고
    • Pharmaceuticals targeting nonsense mutations in genetic diseases
    • &, BioDrugs
    • Rowe SM & Clancy JP (2009) Pharmaceuticals targeting nonsense mutations in genetic diseases: progress in development. BioDrugs 23: 165-174.
    • (2009) progress in development , vol.23 , pp. 165-174
    • Rowe, S.M.1    Clancy, J.P.2
  • 93
    • 4344677977 scopus 로고    scopus 로고
    • GTP hydrolysis by eRF3 facilitates stop codon decoding during eukaryotic translation termination
    • Salas-Marco J & Bedwell DM (2004) GTP hydrolysis by eRF3 facilitates stop codon decoding during eukaryotic translation termination. Mol Cell Biol 24: 7769-7778.
    • (2004) Mol Cell Biol , vol.24 , pp. 7769-7778
    • Salas-Marco, J.1    Bedwell, D.M.2
  • 94
    • 70350654363 scopus 로고    scopus 로고
    • What recent ribosome structures have revealed about the mechanism of translation
    • Schmeing TM & Ramakrishnan V (2009) What recent ribosome structures have revealed about the mechanism of translation. Nature 461: 1234-1242.
    • (2009) Nature , vol.461 , pp. 1234-1242
    • Schmeing, T.M.1    Ramakrishnan, V.2
  • 95
    • 34247200483 scopus 로고    scopus 로고
    • In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis
    • BMC Med
    • Sermet-Gaudelus I, Renouil M, Fajac A et al. (2007) In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study. BMC Med 5: 5.
    • (2007) a pilot study , vol.5 , pp. 5
    • Sermet-Gaudelus, I.1    Renouil, M.2    Fajac, A.3
  • 96
    • 0035138477 scopus 로고    scopus 로고
    • Maintenance of the Gag/Gag-Pol ratio is important for human immunodeficiency virus type 1 RNA dimerization and viral infectivity
    • Shehu-Xhilaga M, Crowe SM & Mak J (2001) Maintenance of the Gag/Gag-Pol ratio is important for human immunodeficiency virus type 1 RNA dimerization and viral infectivity. J Virol 75: 1834-1841.
    • (2001) J Virol , vol.75 , pp. 1834-1841
    • Shehu-Xhilaga, M.1    Crowe, S.M.2    Mak, J.3
  • 97
    • 0035477279 scopus 로고    scopus 로고
    • Identification and characterisation of a developmentally regulated mammalian gene that utilises -1 programmed ribosomal frameshifting
    • Shigemoto K, Brennan J, Walls E, Watson CJ, Stott D, Rigby PW & Reith AD (2001) Identification and characterisation of a developmentally regulated mammalian gene that utilises -1 programmed ribosomal frameshifting. Nucleic Acids Res 29: 4079-4088.
    • (2001) Nucleic Acids Res , vol.29 , pp. 4079-4088
    • Shigemoto, K.1    Brennan, J.2    Walls, E.3    Watson, C.J.4    Stott, D.5    Rigby, P.W.6    Reith, A.D.7
  • 98
    • 0025805098 scopus 로고
    • The signal for a leaky UAG stop codon in several plant viruses includes the two downstream codons
    • Skuzeski JM, Nichols LM, Gesteland RF & Atkins JF (1991) The signal for a leaky UAG stop codon in several plant viruses includes the two downstream codons. J Mol Biol 218: 365-373.
    • (1991) J Mol Biol , vol.218 , pp. 365-373
    • Skuzeski, J.M.1    Nichols, L.M.2    Gesteland, R.F.3    Atkins, J.F.4
  • 99
    • 0027494569 scopus 로고
    • Ribosomal pausing during translation of an RNA pseudoknot
    • Somogyi P, Jenner AJ, Brierley I & Inglis SC (1993) Ribosomal pausing during translation of an RNA pseudoknot. Mol Cell Biol 13: 6931-6940.
    • (1993) Mol Cell Biol , vol.13 , pp. 6931-6940
    • Somogyi, P.1    Jenner, A.J.2    Brierley, I.3    Inglis, S.C.4
  • 100
    • 0034603210 scopus 로고    scopus 로고
    • The crystal structure of human eukaryotic release factor eRF1 - mechanism of stop codon recognition and peptidyl-tRNA hydrolysis
    • Song H, Mugnier P, Das AK et al. (2000) The crystal structure of human eukaryotic release factor eRF1 - mechanism of stop codon recognition and peptidyl-tRNA hydrolysis. Cell 100: 311-321.
    • (2000) Cell , vol.100 , pp. 311-321
    • Song, H.1    Mugnier, P.2    Das, A.K.3
  • 102
    • 0029165882 scopus 로고
    • The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae
    • Stansfield I, Jones KM, Kushnirov VV et al. (1995) The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae. EMBO J 14: 4365-4373.
    • (1995) EMBO J , vol.14 , pp. 4365-4373
    • Stansfield, I.1    Jones, K.M.2    Kushnirov, V.V.3
  • 103
    • 0041660967 scopus 로고    scopus 로고
    • Solution structure of the HIV-1 frameshift inducing stem-loop RNA
    • Staple DW & Butcher SE (2003) Solution structure of the HIV-1 frameshift inducing stem-loop RNA. Nucleic Acids Res 31: 4326-4331.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4326-4331
    • Staple, D.W.1    Butcher, S.E.2
  • 104
    • 20344397919 scopus 로고    scopus 로고
    • Solution structure and thermodynamic investigation of the HIV-1 frameshift inducing element
    • Staple DW & Butcher SE (2005) Solution structure and thermodynamic investigation of the HIV-1 frameshift inducing element. J Mol Biol 349: 1011-1023.
    • (2005) J Mol Biol , vol.349 , pp. 1011-1023
    • Staple, D.W.1    Butcher, S.E.2
  • 106
    • 0035225969 scopus 로고    scopus 로고
    • Modulation of RNA function by oligonucleotides recognizing RNA structure
    • Toulme JJ, Di Primo C & Moreau S (2001) Modulation of RNA function by oligonucleotides recognizing RNA structure. Prog Nucleic Acid Re 69: 1-46.
    • (2001) Prog Nucleic Acid Re , vol.69 , pp. 1-46
    • Toulme, J.J.1    Di Primo, C.2    Moreau, S.3
  • 107
    • 39149144526 scopus 로고    scopus 로고
    • Antiprion drugs as chemical tools to uncover mechanisms of prion propagation
    • Tribouillard D, Gug F, Galons H, Bach S, Saupe SJ & Blondel M (2007) Antiprion drugs as chemical tools to uncover mechanisms of prion propagation. Prion 1: 48-52.
    • (2007) Prion , vol.1 , pp. 48-52
    • Tribouillard, D.1    Gug, F.2    Galons, H.3    Bach, S.4    Saupe, S.J.5    Blondel, M.6
  • 108
    • 0025355475 scopus 로고
    • Translational frameshifting generates the gamma subunit of DNA polymerase III holoenzyme
    • Tsuchihashi Z & Kornberg A (1990) Translational frameshifting generates the gamma subunit of DNA polymerase III holoenzyme. P Natl Acad Sci USA 87: 2516-2520.
    • (1990) P Natl Acad Sci USA , vol.87 , pp. 2516-2520
    • Tsuchihashi, Z.1    Kornberg, A.2
  • 109
    • 0026784740 scopus 로고
    • Enhancement of ribosomal frameshifting by oligonucleotides targeted to the HIV gag-pol region
    • Vickers TA & Ecker DJ (1992) Enhancement of ribosomal frameshifting by oligonucleotides targeted to the HIV gag-pol region. Nucleic Acids Res 20: 3945-3953.
    • (1992) Nucleic Acids Res , vol.20 , pp. 3945-3953
    • Vickers, T.A.1    Ecker, D.J.2
  • 110
    • 0034982292 scopus 로고    scopus 로고
    • Gentamicin treatment of Duchenne and Becker muscular dystrophy due to nonsense mutations
    • Wagner KR, Hamed S, Hadley DW et al. (2001) Gentamicin treatment of Duchenne and Becker muscular dystrophy due to nonsense mutations. Ann Neurol 49: 706-711.
    • (2001) Ann Neurol , vol.49 , pp. 706-711
    • Wagner, K.R.1    Hamed, S.2    Hadley, D.W.3
  • 111
    • 68449092202 scopus 로고    scopus 로고
    • Architecture and secondary structure of an entire HIV-1 RNA genome
    • Watts JM, Dang KK, Gorelick RJ et al. (2009) Architecture and secondary structure of an entire HIV-1 RNA genome. Nature 460: 711-716.
    • (2009) Nature , vol.460 , pp. 711-716
    • Watts, J.M.1    Dang, K.K.2    Gorelick, R.J.3
  • 113
    • 34247588271 scopus 로고    scopus 로고
    • PTC124 targets genetic disorders caused by nonsense mutations
    • Welch EM, Barton ER, Zhuo J et al. (2007) PTC124 targets genetic disorders caused by nonsense mutations. Nature 447: 87-91.
    • (2007) Nature , vol.447 , pp. 87-91
    • Welch, E.M.1    Barton, E.R.2    Zhuo, J.3
  • 115
    • 0034073736 scopus 로고    scopus 로고
    • A pilot study of the effect of gentamicin on nasal potential difference measurements in cystic fibrosis patients carrying stop mutations
    • Wilschanski M, Famini C, Blau H et al. (2000) A pilot study of the effect of gentamicin on nasal potential difference measurements in cystic fibrosis patients carrying stop mutations. Am J Resp Crit Care 161: 860-865.
    • (2000) Am J Resp Crit Care , vol.161 , pp. 860-865
    • Wilschanski, M.1    Famini, C.2    Blau, H.3
  • 117
    • 71549118507 scopus 로고    scopus 로고
    • Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems
    • Yuan J, O'Donoghue P, Ambrogelly A et al. (2010) Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems. FEBS Lett 584: 342-349.
    • (2010) FEBS Lett , vol.584 , pp. 342-349
    • Yuan, J.1    O'Donoghue, P.2    Ambrogelly, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.