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Volumn 59, Issue 3, 2010, Pages 84-95

T-type Ca channel blockade as a determinant of kidney protection

Author keywords

Chronic kidney disease; Efonidipine; Renal microcirculation; T type calcium channels; Voltage dependent Ca channels

Indexed keywords

AMLODIPINE; AZELNIDIPINE; BENIDIPINE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; CILNIDIPINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EFONIDIPINE; FELODIPINE; MEPIRODIPINE; MIBEFRADIL; NIFEDIPINE; NILVADIPINE;

EID: 78249284594     PISSN: 00229717     EISSN: 18801293     Source Type: Journal    
DOI: 10.2302/kjm.59.84     Document Type: Review
Times cited : (45)

References (103)
  • 1
    • 0025265177 scopus 로고
    • The effect of two different calcium antagonists on the glomerular haemodynamics in dogs
    • Heller J, Horacek V: The effect of two different calcium antagonists on the glomerular haemodynamics in dogs. Eur J Physiol 1990; 415: 751-755.
    • (1990) Eur J Physiol , vol.415 , pp. 751-755
    • Heller, J.1    Horacek, V.2
  • 3
    • 0020840917 scopus 로고
    • Effects of vera-pamil on renin and aldosterone in the dog and rat
    • Roy M, Guthrie GP, Holladay FP, Kotchen TA: Effects of vera-pamil on renin and aldosterone in the dog and rat. Am J Physiol 1983; 245: E410-E416.
    • (1983) Am J Physiol , vol.245
    • Roy, M.1    Guthrie, G.P.2    Holladay, F.P.3    Kotchen, T.A.4
  • 4
    • 0024373227 scopus 로고
    • Disparate effects of Ca channel blockers on afferent and efferent arteriolar responses to ANG II
    • Carmines PK, Navar LG: Disparate effects of Ca channel blockers on afferent and efferent arteriolar responses to ANG II. Am J Physiol 1989; 256: F1015-F1020.
    • (1989) Am J Physiol , vol.256
    • Carmines, P.K.1    Navar, L.G.2
  • 5
    • 0021959070 scopus 로고
    • Reversal by the calcium antagonist nisoldipine of norepinephrine-induced reduction of GFR: Evidence for preferential antagonism of preglomeru-lar vasoconstriction
    • Loutzenhiser R, Epstein M, Horton C, Sonke P: Reversal by the calcium antagonist nisoldipine of norepinephrine-induced reduction of GFR: evidence for preferential antagonism of preglomeru-lar vasoconstriction. J Pharmacol Exp Ther 1984; 232: 382-387.
    • (1984) J Pharmacol Exp Ther , vol.232 , pp. 382-387
    • Loutzenhiser, R.1    Epstein, M.2    Horton, C.3    Sonke, P.4
  • 6
    • 0007582257 scopus 로고
    • Renal hemodynamic effects of calcium antagonists
    • In: Epstein M, Loutzenhiser R, Philadelphia, Hanley & Belfus
    • Loutzenhiser R, Epstein M: Renal hemodynamic effects of calcium antagonists. In: Epstein M, Loutzenhiser R (eds) Calcium Antagonists and the Kidney. Philadelphia, Hanley & Belfus, 1990, pp 33-74.
    • (1990) Calcium Antagonists and The Kidney , pp. 33-74
    • Loutzenhiser, R.1    Epstein, M.2
  • 7
    • 0023584303 scopus 로고
    • Calcium antagonists preferentially dilate preglomerular vessels of hydronephrotic kidney
    • Fleming JT, Parekh N, Steinhausen M: Calcium antagonists preferentially dilate preglomerular vessels of hydronephrotic kidney. Am J Physiol 1987; 253: F1157-F1163.
    • (1987) Am J Physiol , vol.253
    • Fleming, J.T.1    Parekh, N.2    Steinhausen, M.3
  • 9
    • 0023255729 scopus 로고
    • Renal autoregulation and vulnerability to hypertensive injury in remnant kidney
    • Bidani AK, Schwartz MM, Lewis EJ: Renal autoregulation and vulnerability to hypertensive injury in remnant kidney. Am J Physiol 1987; 252: F1003-F1010.
    • (1987) Am J Physiol , vol.252
    • Bidani, A.K.1    Schwartz, M.M.2    Lewis, E.J.3
  • 10
    • 0028451064 scopus 로고
    • Method of renal mass reduction is a critical determinant of subsequent hypertension and glo-merular injury
    • Griffin KA, Picken M, Bidani AK: Method of renal mass reduction is a critical determinant of subsequent hypertension and glo-merular injury. J Am Soc Nephrol 1994; 4: 2023-2031.
    • (1994) J Am Soc Nephrol , vol.4 , pp. 2023-2031
    • Griffin, K.A.1    Picken, M.2    Bidani, A.K.3
  • 11
    • 0029091742 scopus 로고
    • Deleterious effects of calcium channel blockers on pressures transmission and glomerular injury in rat remnant kidneys
    • Griffin KA, Picken MM, Bidani AK: Deleterious effects of calcium channel blockers on pressures transmission and glomerular injury in rat remnant kidneys. J Clin Invest 1995; 96: 793-800.
    • (1995) J Clin Invest , vol.96 , pp. 793-800
    • Griffin, K.A.1    Picken, M.M.2    Bidani, A.K.3
  • 12
    • 0032946830 scopus 로고    scopus 로고
    • Class differences in the effects of calcium channel blockers in the rat remnant kidney model
    • Griffin KA, Picken MM, Bakris GL, Bidani AK: Class differences in the effects of calcium channel blockers in the rat remnant kidney model. Kidney Int 1999; 55: 1849-1860.
    • (1999) Kidney Int , vol.55 , pp. 1849-1860
    • Griffin, K.A.1    Picken, M.M.2    Bakris, G.L.3    Bidani, A.K.4
  • 13
    • 0033713292 scopus 로고    scopus 로고
    • Nomenclature of voltage-gated calcium channels
    • Ertel EA, Campbell KP, Harpold MM, et al: Nomenclature of voltage-gated calcium channels. Neuron 2000; 25: 533-535.
    • (2000) Neuron , vol.25 , pp. 533-535
    • Ertel, E.A.1    Campbell, K.P.2    Harpold, M.M.3
  • 14
    • 0037207469 scopus 로고    scopus 로고
    • Molecular physiology of low-voltage-activated T-type calcium channels
    • Perez-Reyes E: Molecular physiology of low-voltage-activated T-type calcium channels. Physiol Rev 2003; 83: 117-161.
    • (2003) Physiol Rev , vol.83 , pp. 117-161
    • Perez-Reyes, E.1
  • 15
    • 28044464474 scopus 로고    scopus 로고
    • Pathophysiological significance of T-type Ca2+ channels: Properties and functional roles of T-type Ca2+ channels in cardiac pacemaking
    • Ono K, Iijima T: Pathophysiological significance of T-type Ca2+ channels: properties and functional roles of T-type Ca2+ channels in cardiac pacemaking. J Pharmacol Sci 2005; 99: 197-204.
    • (2005) J Pharmacol Sci , vol.99 , pp. 197-204
    • Ono, K.1    Iijima, T.2
  • 16
    • 0034634275 scopus 로고    scopus 로고
    • Vascular smooth muscle cells express the alpha(1A) subunit of a P-/Q-type voltage-dependent Ca(2+) channel, and it is functionally important in renal afferent arterioles
    • Hansen PB, Jensen BL, Andreasen D, Friis UG, Skott O: Vascular smooth muscle cells express the alpha(1A) subunit of a P-/Q-type voltage-dependent Ca(2+) channel, and it is functionally important in renal afferent arterioles. Circ Res 2000; 87: 896-902.
    • (2000) Circ Res , vol.87 , pp. 896-902
    • Hansen, P.B.1    Jensen, B.L.2    Andreasen, D.3    Friis, U.G.4    Skott, O.5
  • 17
    • 0035964911 scopus 로고    scopus 로고
    • Differential expression of T- and L-type voltage-dependent calcium channels in renal resistance vessels
    • Hansen PB, Jensen BL, Andreasen D, Skøtt O: Differential expression of T- and L-type voltage-dependent calcium channels in renal resistance vessels. Circ Res 2001; 89: 630-638.
    • (2001) Circ Res , vol.89 , pp. 630-638
    • Hansen, P.B.1    Jensen, B.L.2    Andreasen, D.3    Skøtt, O.4
  • 18
    • 0028588042 scopus 로고
    • Renal protective effect of efonidipine hydro-chloride (NZ-105), a new calcium antagonist, in spontaneously hypertensive rats
    • Shudo C, Masuda Y, Sugita H, Furukawa S, Hayashi K, Hirata H, Tanaka S, Tomita K: Renal protective effect of efonidipine hydro-chloride (NZ-105), a new calcium antagonist, in spontaneously hypertensive rats. Gen Pharmacol 1994; 25: 1567-1575.
    • (1994) Gen Pharmacol , vol.25 , pp. 1567-1575
    • Shudo, C.1    Masuda, Y.2    Sugita, H.3    Furukawa, S.4    Hayashi, K.5    Hirata, H.6    Tanaka, S.7    Tomita, K.8
  • 19
    • 0031922876 scopus 로고    scopus 로고
    • Saruta T: Renal protective effects of efonidipine in partially nephrectomized spontaneously hypertensive rats
    • Fujiwara K, Kanno Y, Hayashi K, Takenaka T, Saruta T: Renal protective effects of efonidipine in partially nephrectomized spontaneously hypertensive rats. Clin Exp Hypertens 1998; 20: 295- 312.
    • (1998) Clin Exp Hypertens , vol.20 , pp. 295-312
    • Fujiwara, K.1    Kanno, Y.2    Hayashi, K.3    Takenaka, T.4
  • 20
    • 0032701555 scopus 로고    scopus 로고
    • Contrasting effects of selective T- an L-type calcium channel blockade on glomerular damage in DOCA hypertensive rats
    • Karam H, Clozel J-P, Bruneval P, Gonzalez M-F, Ménard J: Contrasting effects of selective T- an L-type calcium channel blockade on glomerular damage in DOCA hypertensive rats. Hypertension 1999; 34: 673-678.
    • (1999) Hypertension , vol.34 , pp. 673-678
    • Karam, H.1    Clozel, J.-P.2    Bruneval, P.3    Gonzalez, M.-F.4    Ménard, J.5
  • 21
    • 0037307604 scopus 로고    scopus 로고
    • Effects of efonidipine and ACE inhibitors on proteinuria in human hypertension with renal impairment
    • Hayashi K, Kumagai H, Saruta T: Effects of efonidipine and ACE inhibitors on proteinuria in human hypertension with renal impairment. Am J Hypertens 2003; 16: 116-122.
    • (2003) Am J Hypertens , vol.16 , pp. 116-122
    • Hayashi, K.1    Kumagai, H.2    Saruta, T.3
  • 22
    • 0035723064 scopus 로고    scopus 로고
    • Comparison of L-type and mixed Land T-type calcium channel blockers on kidney injury caused by deoxycorticosterone-salt hypertension in rats
    • Baylis C, Qiu C, Engels K: Comparison of L-type and mixed Land T-type calcium channel blockers on kidney injury caused by deoxycorticosterone-salt hypertension in rats. Am J Kidney Dis 2001; 38: 1292-1297.
    • (2001) Am J Kidney Dis , vol.38 , pp. 1292-1297
    • Baylis, C.1    Qiu, C.2    Engels, K.3
  • 23
    • 68249152209 scopus 로고    scopus 로고
    • Influence of T-calcium channel blocker treatment on deterioration of renal function in chronic kidney disease
    • Omae K, Ogawa T, Nitta K: Influence of T-calcium channel blocker treatment on deterioration of renal function in chronic kidney disease. Heart Vessels 2009; 24: 301-307.
    • (2009) Heart Vessels , vol.24 , pp. 301-307
    • Omae, K.1    Ogawa, T.2    Nitta, K.3
  • 24
    • 1242319239 scopus 로고    scopus 로고
    • The impact of splice isoforms on voltage-gated calcium channel α1 subunits
    • Jurkat-Rott K, Lehmann-Horn F: The impact of splice isoforms on voltage-gated calcium channel α1 subunits. J Physiol 2003; 554; 609-619.
    • (2003) J Physiol , vol.554 , pp. 609-619
    • Jurkat-Rott, K.1    Lehmann-Horn, F.2
  • 26
    • 0022973258 scopus 로고
    • Atrial natriuretic pep-tide causes pre-glomerular vasodilatation and post-glomerular va-soconstriction in rat kidney
    • Marin-Grez M, Fleming JT, Steinhausen M: Atrial natriuretic pep-tide causes pre-glomerular vasodilatation and post-glomerular va-soconstriction in rat kidney. Nature 1986; 324: 473-476.
    • (1986) Nature , vol.324 , pp. 473-476
    • Marin-Grez, M.1    Fleming, J.T.2    Steinhausen, M.3
  • 27
    • 0023753726 scopus 로고
    • A trial natriuretic peptide reverses afferent arteriolar vasoconstriction and potentiates efferent arteriolar vasoconstriction in the isolated perfused rat kidney
    • Loutzenhiser R, Hayashi K, Epstein M: A trial natriuretic peptide reverses afferent arteriolar vasoconstriction and potentiates efferent arteriolar vasoconstriction in the isolated perfused rat kidney. J Pharmacol Exp Ther 1988; 246: 522-528.
    • (1988) J Pharmacol Exp Ther , vol.246 , pp. 522-528
    • Loutzenhiser, R.1    Hayashi, K.2    Epstein, M.3
  • 28
    • 0024844623 scopus 로고
    • Pressure-induced vaso-constriction of renal microvessels in normotensive and hypertensive rats: Studies in the isolated perfused hydronephrotic kidney
    • Hayashi K, Epstein M, Loutzenhiser R: Pressure-induced vaso-constriction of renal microvessels in normotensive and hypertensive rats: studies in the isolated perfused hydronephrotic kidney. Circ Res 1989; 65: 1475-1484.
    • (1989) Circ Res , vol.65 , pp. 1475-1484
    • Hayashi, K.1    Epstein, M.2    Loutzenhiser, R.3
  • 29
    • 0025103352 scopus 로고
    • Direct visualization of effects of endothelin on the renal microvasculature
    • Loutzenhiser R, Epstein M, Hayashi K, Horton C: Direct visualization of effects of endothelin on the renal microvasculature. Am J Physiol 1990; 258: F61-F68.
    • (1990) Am J Physiol , vol.258
    • Loutzenhiser, R.1    Epstein, M.2    Hayashi, K.3    Horton, C.4
  • 30
    • 0024437322 scopus 로고
    • Divergent effects of KCl-induced depolarization on afferent and efferent arterioles
    • Loutzenhiser R, Hayashi K, Epstein M: Divergent effects of KCl-induced depolarization on afferent and efferent arterioles. Am J Physiol 1989; 257: F561-F564.
    • (1989) Am J Physiol , vol.257
    • Loutzenhiser, R.1    Hayashi, K.2    Epstein, M.3
  • 31
    • 0022107010 scopus 로고
    • Intracellular recordings from renin-positive cells of the afferent glomerular arteriole
    • Bührle CP, Nobiling R, Taugner R: Intracellular recordings from renin-positive cells of the afferent glomerular arteriole. Am J Physiol 1985; 249: F272-F281.
    • (1985) Am J Physiol , vol.249
    • Bührle, C.P.1    Nobiling, R.2    Taugner, R.3
  • 32
    • 0027138546 scopus 로고
    • Segmental distinct effects of depolarization on intracellular [Ca2+] in renal arterioles
    • Carmines PK, Fower BC, Bell PD: Segmental distinct effects of depolarization on intracellular [Ca2+] in renal arterioles. Am J Physiol 1993; 265: F677-F685.
    • (1993) Am J Physiol , vol.265
    • Carmines, P.K.1    Fower, B.C.2    Bell, P.D.3
  • 33
    • 0006370437 scopus 로고
    • Vasomotion and vasoconstriction induced by a Ca agonist in the split hydronephrotic kidney
    • Steinhausen M, Baehr M: Vasomotion and vasoconstriction induced by a Ca agonist in the split hydronephrotic kidney. Prog Appl Microcirc 1989; 14: 25-29.
    • (1989) Prog Appl Microcirc , vol.14 , pp. 25-29
    • Steinhausen, M.1    Baehr, M.2
  • 34
    • 0043107912 scopus 로고
    • Acute and chronic effects of calcium antagonists on the essential hypertensive kidney
    • In: Epstein M, Lout-zenhiser R, Philadelphia, Hanley & Belfus
    • Reams GP, Bauer JH: Acute and chronic effects of calcium antagonists on the essential hypertensive kidney. In: Epstein M, Lout-zenhiser R (eds) Calcium Antagonists and the Kidney. Philadelphia, Hanley & Belfus, 1990, pp 247-256.
    • (1990) Calcium Antagonists and The Kidney , pp. 247-256
    • Reams, G.P.1    Bauer, J.H.2
  • 35
    • 0029788759 scopus 로고    scopus 로고
    • Will angiotensin II receptor antagonists be renopro-tective in humans?
    • Ichikawa I: Will angiotensin II receptor antagonists be renopro-tective in humans? Kidney Int 1996; 50: 684-692.
    • (1996) Kidney Int , vol.50 , pp. 684-692
    • Ichikawa, I.1
  • 36
    • 0022000420 scopus 로고
    • Effects of diltiazem and manganese on renal hemodynamics: Studies in the isolated perfused rat kidney
    • Loutzenhiser R, Horton C, Epstein M: Effects of diltiazem and manganese on renal hemodynamics: studies in the isolated perfused rat kidney. Nephron. 1985; 39: 382-388.
    • (1985) Nephron , vol.39 , pp. 382-388
    • Loutzenhiser, R.1    Horton, C.2    Epstein, M.3
  • 37
    • 0024423338 scopus 로고
    • Horton C: Effects of am-lodipine on renal hemodynamics
    • Loutzenhiser R, Epstein M, Fischetti F, Horton C: Effects of am-lodipine on renal hemodynamics. Am J Cardiol 1989; 64: 122I- 127I.
    • (1989) Am J Cardiol , vol.64
    • Loutzenhiser, R.1    Epstein, M.2    Fischetti, F.3
  • 38
    • 0023584593 scopus 로고
    • Modification of the renal hemody-namic response to vasoconstrictors by calcium antagonists
    • Loutzenhiser R, Epstein M: Modification of the renal hemody-namic response to vasoconstrictors by calcium antagonists. Am J Nephrol 1987; 7 (Suppl 1): 7-16.
    • (1987) Am J Nephrol , vol.7 , Issue.SUPPL. 1 , pp. 7-16
    • Loutzenhiser, R.1    Epstein, M.2
  • 39
    • 0020758598 scopus 로고
    • Segmental effects of norepinephrine and angioten-sin II on isolated renal microvessels
    • Edwards RM: Segmental effects of norepinephrine and angioten-sin II on isolated renal microvessels. Am J Physiol. 1983; 244: F526-F534.
    • (1983) Am J Physiol , vol.244
    • Edwards, R.M.1
  • 40
    • 0025308375 scopus 로고
    • Effects of angiotensin II and norepinephrine on isolated rat afferent and efferent arterioles
    • Yuan B, Robinette JB, Conger JD: Effects of angiotensin II and norepinephrine on isolated rat afferent and efferent arterioles. Am J Physiol 1990; 258: F741-F750.
    • (1990) Am J Physiol , vol.258
    • Yuan, B.1    Robinette, J.B.2    Conger, J.D.3
  • 41
    • 0025243378 scopus 로고
    • An in vitro approach to the study of macula densa-mediated glomerular hemodynamics
    • Ito S, Carretero OA: An in vitro approach to the study of macula densa-mediated glomerular hemodynamics. Kidney Int 1990; 38: 1206-1210.
    • (1990) Kidney Int , vol.38 , pp. 1206-1210
    • Ito, S.1    Carretero, O.A.2
  • 42
    • 0027222109 scopus 로고
    • Evidence for the role of nitric oxide in macula densa control of glomerular hemodynamics
    • Ito S, Ren Y: Evidence for the role of nitric oxide in macula densa control of glomerular hemodynamics. J Clin Invest 1993; 92: 1093-1098.
    • (1993) J Clin Invest , vol.92 , pp. 1093-1098
    • Ito, S.1    Ren, Y.2
  • 43
    • 18144437821 scopus 로고
    • Navar LG: In vitro perfusion of juxtamedullary neph-rons in rats
    • Casellas D, Navar LG: In vitro perfusion of juxtamedullary neph-rons in rats. Am J Physiol 1984; 246: F349-F358.
    • (1984) Am J Physiol , vol.246
    • Casellas, D.1
  • 44
    • 0020537942 scopus 로고
    • Hydro-nephrosis: A new method to visualize vas afferens, efferens, and glomerular network
    • Steinhausen M, Snoei H, Parekh N, Baker R, Johnson PC: Hydro-nephrosis: A new method to visualize vas afferens, efferens, and glomerular network. Kidney Int 1983; 23: 794-806.
    • (1983) Kidney Int , vol.23 , pp. 794-806
    • Steinhausen, M.1    Snoei, H.2    Parekh, N.3    Baker, R.4    Johnson, P.C.5
  • 45
    • 0034955116 scopus 로고    scopus 로고
    • In vivo visualization of tubuloglomerular feedback- and angiotensin II-induced renal vasoconstriction in dogs by an intravital pencil lens-probe video-microscope
    • Yamamoto T, Hayashi K, Matsuda H, et al: In vivo visualization of tubuloglomerular feedback- and angiotensin II-induced renal vasoconstriction in dogs by an intravital pencil lens-probe video-microscope. Kidney Int 2001; 60: 364-369.
    • (2001) Kidney Int , vol.60 , pp. 364-369
    • Yamamoto, T.1    Hayashi, K.2    Matsuda, H.3
  • 46
    • 0024373227 scopus 로고
    • Disparate effects of Ca channel blockers on afferent and efferent arteriolar responses to ANG II
    • Carmines PK, Navar LG: Disparate effects of Ca channel blockers on afferent and efferent arteriolar responses to ANG II. Am J Physiol 1989; 256: F1015-F1020.
    • (1989) Am J Physiol , vol.256
    • Carmines, P.K.1    Navar, L.G.2
  • 48
    • 0029927951 scopus 로고    scopus 로고
    • Disparate effects of calcium antagonists on renal microcirculation
    • Hayashi K, Nagahama T, Oka K, Epstein M, Saruta T: Disparate effects of calcium antagonists on renal microcirculation. Hyper-tens Res 1996; 19: 31-36.
    • (1996) Hyper-tens Res , vol.19 , pp. 31-36
    • Hayashi, K.1    Nagahama, T.2    Oka, K.3    Epstein, M.4    Saruta, T.5
  • 49
    • 0002903245 scopus 로고    scopus 로고
    • Antihypertensive agents and renal protection: Calcium channel blockers
    • Saruta T, Kanno Y, Hayashi K, Konishi K: Antihypertensive agents and renal protection: Calcium channel blockers. Kidney Int 49 (Suppl) 1996; 55: S52-S56.
    • (1996) Kidney Int 49 (Suppl) , vol.55
    • Saruta, T.1    Kanno, Y.2    Hayashi, K.3    Konishi, K.4
  • 50
    • 0034756707 scopus 로고    scopus 로고
    • Divergent renal vasodilator action of L- and T-type calcium antagonists in vivo
    • Honda M, Hayashi K, Matsuda H, et al: Divergent renal vasodilator action of L- and T-type calcium antagonists in vivo. J Hyper-tens 2001; 9: 2031-2037.
    • (2001) J Hyper-tens , vol.9 , pp. 2031-2037
    • Honda, M.1    Hayashi, K.2    Matsuda, H.3
  • 53
    • 0032935843 scopus 로고    scopus 로고
    • Renal afferent and efferent arteriolar dilation by nilvadipine: Studies in the isolated perfused hydronephrotic kidney
    • Ozawa Y, Hayashi K, Nagahama T, Fujiwara K, Wakino S, Saruta T: Renal afferent and efferent arteriolar dilation by nilvadipine: studies in the isolated perfused hydronephrotic kidney. J Cardio-vasc Pharmacol 1999; 33: 243-247.
    • (1999) J Cardio-vasc Pharmacol , vol.33 , pp. 243-247
    • Ozawa, Y.1    Hayashi, K.2    Nagahama, T.3    Fujiwara, K.4    Wakino, S.5    Saruta, T.6
  • 55
    • 0032822473 scopus 로고    scopus 로고
    • Differential effects of T- and L-type calcium antagonists on glomerular dynamics in spontaneously hypertensive rats
    • Nakamura Y, Ono H, Frohlich ED: Differential effects of T- and L-type calcium antagonists on glomerular dynamics in spontaneously hypertensive rats. Hypertension 1999; 34: 273-278.
    • (1999) Hypertension , vol.34 , pp. 273-278
    • Nakamura, Y.1    Ono, H.2    Frohlich, E.D.3
  • 56
    • 0035570642 scopus 로고    scopus 로고
    • Effect of T-type selective calcium antagonist on renal microcirculation: Studies in the isolated perfused hydronephrotic kidney
    • Ozawa Y, Hayashi K, Nagahama T, Fujiwara K, Saruta T: Effect of T-type selective calcium antagonist on renal microcirculation: studies in the isolated perfused hydronephrotic kidney. Hypertension 2001; 38: 343-347.
    • (2001) Hypertension , vol.38 , pp. 343-347
    • Ozawa, Y.1    Hayashi, K.2    Nagahama, T.3    Fujiwara, K.4    Saruta, T.5
  • 57
    • 0036563247 scopus 로고    scopus 로고
    • N- and L-type calcium channel antagonist improves glomerular dynamics, reverses severe nephrosclerosis, and inhibits apoptosis and proliferation in an L-NAME/SHR model
    • Zhou X, Ono H, Ono Y, Frohlich ED: N- and L-type calcium channel antagonist improves glomerular dynamics, reverses severe nephrosclerosis, and inhibits apoptosis and proliferation in an L-NAME/SHR model. J Hypertens 2002; 20: 993-1000.
    • (2002) J Hypertens , vol.20 , pp. 993-1000
    • Zhou, X.1    Ono, H.2    Ono, Y.3    Frohlich, E.D.4
  • 59
    • 0028865517 scopus 로고
    • Inhibitory effect of cilnidipine on vascular sympathetic neurotransmission and subsequent vasoconstriction in spontaneously hypertensive rats
    • Hosono M, Fujii S, Hiruma T, Watanabe K, Hayashi Y, Ohnishi H, Takata Y, Kato H: Inhibitory effect of cilnidipine on vascular sympathetic neurotransmission and subsequent vasoconstriction in spontaneously hypertensive rats. Jpn J Pharmacol 1995; 69: 127-134.
    • (1995) Jpn J Pharmacol , vol.69 , pp. 127-134
    • Hosono, M.1    Fujii, S.2    Hiruma, T.3    Watanabe, K.4    Hayashi, Y.5    Ohnishi, H.6    Takata, Y.7    Kato, H.8
  • 60
    • 2942580721 scopus 로고    scopus 로고
    • The evaluation of the N-type channel blocking properties of cilnidip-ine and other voltage-dependent calcium antagonists
    • Nap A, Mathy MJ, Balt JC, Pfaffendorf M, van Zwieten PA: The evaluation of the N-type channel blocking properties of cilnidip-ine and other voltage-dependent calcium antagonists. Fundam Clin Pharmacol 2004; 18: 309-319.
    • (2004) Fundam Clin Pharmacol , vol.18 , pp. 309-319
    • Nap, A.1    Mathy, M.J.2    Balt, J.C.3    Pfaffendorf, M.4    van Zwieten, P.A.5
  • 61
    • 0030819213 scopus 로고    scopus 로고
    • Cilnidip-ine attenuates renal nerve stimulation-induced renal vasoconstric-tion and antinatriuresis in anesthetized dogs
    • Takahara A, Dohmoto H, Hisa H, Satoh S, Yoshimoto R: Cilnidip-ine attenuates renal nerve stimulation-induced renal vasoconstric-tion and antinatriuresis in anesthetized dogs. Jpn J Pharmacol. 1997; 75: 27-32.
    • (1997) Jpn J Pharmacol , vol.75 , pp. 27-32
    • Takahara, A.1    Dohmoto, H.2    Hisa, H.3    Satoh, S.4    Yoshimoto, R.5
  • 63
    • 0024253737 scopus 로고
    • Ichikawa I: "Intact nephrons" as the primary origin of proteinuria in chronic renal disease. Study in the rat model of subtotal nephrectomy
    • Yoshioka T, Shiraga H, Yoshida Y, Fogo A, Glick AD, Deen WM, Hoyer JR, Ichikawa I: "Intact nephrons" as the primary origin of proteinuria in chronic renal disease. Study in the rat model of subtotal nephrectomy. J Clin Invest 1988; 82: 1614-1623.
    • (1988) J Clin Invest , vol.82 , pp. 1614-1623
    • Yoshioka, T.1    Shiraga, H.2    Yoshida, Y.3    Fogo, A.4    Glick, A.D.5    Deen, W.M.6    Hoyer, J.R.7
  • 64
    • 0023158661 scopus 로고
    • Verapamil protects against progression of experimental chronic renal disease
    • Harris DC, Hammond WS, Burke TJ, Schrier RW: Verapamil protects against progression of experimental chronic renal disease. Kidney Int 1987; 31: 41-46.
    • (1987) Kidney Int , vol.31 , pp. 41-46
    • Harris, D.C.1    Hammond, W.S.2    Burke, T.J.3    Schrier, R.W.4
  • 66
    • 0026729390 scopus 로고
    • Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension
    • Wenzel UO, Troschau G, Schoeppe W, Helmchen U, Schwietzer G: Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension. Hypertension 1992; 20: 233-241.
    • (1992) Hypertension , vol.20 , pp. 233-241
    • Wenzel, U.O.1    Troschau, G.2    Schoeppe, W.3    Helmchen, U.4    Schwietzer, G.5
  • 67
    • 0025812269 scopus 로고
    • Impaired autoregulation of glomerular capillary hydrostatic pressure in the rat remnant nephron
    • Pelayo JC, Westoo JY: Impaired autoregulation of glomerular capillary hydrostatic pressure in the rat remnant nephron. J Clin Invest 1991; 88: 101-105.
    • (1991) J Clin Invest , vol.88 , pp. 101-105
    • Pelayo, J.C.1    Westoo, J.Y.2
  • 68
    • 84988198153 scopus 로고
    • Beneficial effect of efonidipine hydrochloride (NZ-105) on proteinuria in aged spontaneously hypertensive rats (SHR)
    • Shudo C, Masuda Y, Sugita H: Beneficial effect of efonidipine hydrochloride (NZ-105) on proteinuria in aged spontaneously hypertensive rats (SHR). Pharm Sci 1995; 1: 333-335.
    • (1995) Pharm Sci , vol.1 , pp. 333-335
    • Shudo, C.1    Masuda, Y.2    Sugita, H.3
  • 69
    • 9544234453 scopus 로고    scopus 로고
    • Effects of efonidipine, nicar-dipine and captopril on proteinuria in aged spontaneously hypertensive rats
    • Shudo C, Masuda Y, Sugita H, et al: Effects of efonidipine, nicar-dipine and captopril on proteinuria in aged spontaneously hypertensive rats. Arzneimittel Forschung 1996; 46: 852-854.
    • (1996) Arzneimittel Forschung , vol.46 , pp. 852-854
    • Shudo, C.1    Masuda, Y.2    Sugita, H.3
  • 70
    • 33646445167 scopus 로고    scopus 로고
    • Yamamoto H: Effects of L/N-type calcium channel antagonist, cilnidipine on progressive renal injuries in Dahl salt-sensitive rats
    • Konda T, Enomoto A, Takahara A, Yamamoto H: Effects of L/N-type calcium channel antagonist, cilnidipine on progressive renal injuries in Dahl salt-sensitive rats. Biol Pharm Bull 2006; 29: 933 -937.
    • (2006) Biol Pharm Bull , vol.29 , pp. 933-937
    • Konda, T.1    Enomoto, A.2    Takahara, A.3
  • 71
    • 23844487058 scopus 로고    scopus 로고
    • The N- and L-type calcium channel blocker cilnidipine suppresses renal injury in Dahl rats fed a high-sucrose diet, an experimental model of metabolic syndrome
    • Konda T, Enomoto A, Matsushita J, Takahara A, Moriyama T: The N- and L-type calcium channel blocker cilnidipine suppresses renal injury in Dahl rats fed a high-sucrose diet, an experimental model of metabolic syndrome. Nephron Physiol 2005; 101: 1-13.
    • (2005) Nephron Physiol , vol.101 , pp. 1-13
    • Konda, T.1    Enomoto, A.2    Matsushita, J.3    Takahara, A.4    Moriyama, T.5
  • 72
    • 0031922876 scopus 로고    scopus 로고
    • Renal protective effects of efonidipine hydrochloride in subtotally ne-phrectomized spontaneously hypertensive rats
    • Fujiwara K, Hayashi K, Kanno Y, Takenaka T, Saruta T: Renal protective effects of efonidipine hydrochloride in subtotally ne-phrectomized spontaneously hypertensive rats. Clin Exp Hyper-tens 1998; 23: 295-312.
    • (1998) Clin Exp Hyper-tens , vol.23 , pp. 295-312
    • Fujiwara, K.1    Hayashi, K.2    Kanno, Y.3    Takenaka, T.4    Saruta, T.5
  • 73
    • 0034092516 scopus 로고    scopus 로고
    • Calcium channel blockers inhibit proliferation and matrix production in rat me-sangial cells: Possible mechanism of suppression of AP-1 and CREB activities
    • Sugiura T, Imai E, Moriyama T, Horio M, Hori M: Calcium channel blockers inhibit proliferation and matrix production in rat me-sangial cells: possible mechanism of suppression of AP-1 and CREB activities. Nephron 2000; 85: 71-80.
    • (2000) Nephron , vol.85 , pp. 71-80
    • Sugiura, T.1    Imai, E.2    Moriyama, T.3    Horio, M.4    Hori, M.5
  • 75
    • 0033794776 scopus 로고    scopus 로고
    • The effects of calcium channel blockers on nuclear factor kappa B activation in the mesangial cells
    • Hayashi M, Yamaji Y, Nakazato Y, Saruta T: The effects of calcium channel blockers on nuclear factor kappa B activation in the mesangial cells. Hypertens Res 2000; 23: 521-525.
    • (2000) Hypertens Res , vol.23 , pp. 521-525
    • Hayashi, M.1    Yamaji, Y.2    Nakazato, Y.3    Saruta, T.4
  • 76
    • 0037118682 scopus 로고    scopus 로고
    • Nifedipine indirectly upregu-lates superoxide dismutase expression in endothelial cells via vascular smooth muscle cell-dependent pathways
    • Fukuo K, Yang J, Yasuda O, et al: Nifedipine indirectly upregu-lates superoxide dismutase expression in endothelial cells via vascular smooth muscle cell-dependent pathways. Circulation 2002; 106: 356-361.
    • (2002) Circulation , vol.106 , pp. 356-361
    • Fukuo, K.1    Yang, J.2    Yasuda, O.3
  • 77
    • 0032253670 scopus 로고    scopus 로고
    • Inhibitory action of mibefradil on calcium signaling and aldosterone synthesis in bovine adrenal glomerulosa cells
    • Rossier MF, Ertel EA, Vallotton MB, Capponi AM: Inhibitory action of mibefradil on calcium signaling and aldosterone synthesis in bovine adrenal glomerulosa cells. J Pharmacol Exp Ther. 1998; 287: 824-831.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 824-831
    • Rossier, M.F.1    Ertel, E.A.2    Vallotton, M.B.3    Capponi, A.M.4
  • 78
    • 67649669261 scopus 로고    scopus 로고
    • Regulation of aldoste-rone and cortisol production by the transcriptional repressor neuron restrictive silencer factor
    • Somekawa S, Imagawa K, Naya N, et al: Regulation of aldoste-rone and cortisol production by the transcriptional repressor neuron restrictive silencer factor. Endocrinology, 2009; 150: 3110-3117.
    • (2009) Endocrinology , vol.150 , pp. 3110-3117
    • Somekawa, S.1    Imagawa, K.2    Naya, N.3
  • 79
    • 34948896521 scopus 로고    scopus 로고
    • Comparison of the effects of efonidipine and amlodipine on aldo-sterone in patients with hypertension
    • Tanaka T, Tsutamoto T, Sakai H, Fuji M, Yamamoto T, Horie M: Comparison of the effects of efonidipine and amlodipine on aldo-sterone in patients with hypertension. Hypertens Res 2007; 30: 691-697.
    • (2007) Hypertens Res , vol.30 , pp. 691-697
    • Tanaka, T.1    Tsutamoto, T.2    Sakai, H.3    Fuji, M.4    Yamamoto, T.5    Horie, M.6
  • 80
    • 34548028268 scopus 로고    scopus 로고
    • Efonidipine reduces proteinuria and plasma aldosterone in patients with chronic glo-merulonephritis
    • Ishimitsu T, Kameda T, Akashiba A, et al: Efonidipine reduces proteinuria and plasma aldosterone in patients with chronic glo-merulonephritis. Hypertens Res 2007; 30: 621-626.
    • (2007) Hypertens Res , vol.30 , pp. 621-626
    • Ishimitsu, T.1    Kameda, T.2    Akashiba, A.3
  • 81
    • 2342567070 scopus 로고    scopus 로고
    • McMahon EG: Aldosterone target organ protection by eplerenone
    • Rudolph AE, Rocha R, McMahon EG: Aldosterone target organ protection by eplerenone. Mol Cell Endocrinol. 2004; 217: 229- 238.
    • (2004) Mol Cell Endocrinol , vol.217 , pp. 229-238
    • Rudolph, A.E.1    Rocha, R.2
  • 82
    • 0344514708 scopus 로고    scopus 로고
    • Effect of fasudil on Rho-kinase and nephropathy in subtotally ne-phrectomized spontaneously hypertensive rats
    • Kanda T, Wakino S, Hayashi K, Homma K, Ozawa Y, Saruta T: Effect of fasudil on Rho-kinase and nephropathy in subtotally ne-phrectomized spontaneously hypertensive rats. Kidney Int. 2003; 64: 2009-2019.
    • (2003) Kidney Int , vol.64 , pp. 2009-2019
    • Kanda, T.1    Wakino, S.2    Hayashi, K.3    Homma, K.4    Ozawa, Y.5    Saruta, T.6
  • 83
    • 4344704302 scopus 로고    scopus 로고
    • Fasudil, a Rho-kinase inhibitor, attenuates glomerulosclerosis in Dahl salt-sensitive rats
    • Nishikimi T, Akimoto K, Wang X, et al: Fasudil, a Rho-kinase inhibitor, attenuates glomerulosclerosis in Dahl salt-sensitive rats. J Hypertens. 2004; 22: 1787-1796.
    • (2004) J Hypertens , vol.22 , pp. 1787-1796
    • Nishikimi, T.1    Akimoto, K.2    Wang, X.3
  • 84
    • 31544433970 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutic strategies of chronic renal injury: Renoprotective effect of Rho-ki-nase inhibitor in hypertensive glomerulosclerosis
    • Nishikimi T, Matsuoka H: Molecular mechanisms and therapeutic strategies of chronic renal injury: renoprotective effect of Rho-ki-nase inhibitor in hypertensive glomerulosclerosis. J Pharmacol Sci 2006; 100: 22-28.
    • (2006) J Pharmacol Sci , vol.100 , pp. 22-28
    • Nishikimi, T.1    Matsuoka, H.2
  • 86
    • 0030656619 scopus 로고    scopus 로고
    • Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
    • Uehata M, Ishizaki T, Satoh H, et al: Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997; 389: 990-994.
    • (1997) Nature , vol.389 , pp. 990-994
    • Uehata, M.1    Ishizaki, T.2    Satoh, H.3
  • 87
    • 40849085208 scopus 로고    scopus 로고
    • T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy
    • Sugano N, Wakino S, Kanda T, et al: T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy. Kidney Int 2008; 73; 826-834.
    • (2008) Kidney Int , vol.73 , pp. 826-834
    • Sugano, N.1    Wakino, S.2    Kanda, T.3
  • 88
    • 0141996311 scopus 로고    scopus 로고
    • Rho GTPases as therapeutic targets for the treatment of inflammatory diseases
    • Zhao D, Pothoulakis C: Rho GTPases as therapeutic targets for the treatment of inflammatory diseases. Expert Opin Ther Targets 2003; 7: 583-592.
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 583-592
    • Zhao, D.1    Pothoulakis, C.2
  • 89
    • 0344373794 scopus 로고    scopus 로고
    • Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretics
    • The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group
    • The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group: Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretics. JAMA 2003; 288: 2981-2997.
    • (2003) JAMA , vol.288 , pp. 2981-2997
  • 91
    • 0035816018 scopus 로고    scopus 로고
    • African American Study of Kidney Disease and Hypertension (AASK) Study Group: Effect of ramipril vs. amlodipine on renal outcomes in hypertensive nephrosclerosis: A randomized controlled trial
    • Agodoa LY, Appel L, Bakris GL, et al; African American Study of Kidney Disease and Hypertension (AASK) Study Group: Effect of ramipril vs. amlodipine on renal outcomes in hypertensive nephrosclerosis: a randomized controlled trial. JAMA 2002; 285: 2719-2728.
    • (2002) JAMA , vol.285 , pp. 2719-2728
    • Agodoa, L.Y.1    Appel, L.2    Bakris, G.L.3
  • 92
    • 15844414184 scopus 로고    scopus 로고
    • REIN-2 Study Group: Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): Multicentre, randomised controlled trial
    • Ruggenenti P, Perna A, Loriga G, et al; REIN-2 Study Group: Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): multicentre, randomised controlled trial. Lancet 2005; 365: 939-946.
    • (2005) Lancet , vol.365 , pp. 939-946
    • Ruggenenti, P.1    Perna, A.2    Loriga, G.3
  • 93
    • 33644912981 scopus 로고    scopus 로고
    • Independent and additive impact of blood pressure control and angiotensin II receptor blockade on renal outcomes in the irbesartan diabetic ne-phropathy trial: Clinical implications and limitations
    • Pohl MA, Blumenthal S, Cordonnier DJ, et al: Independent and additive impact of blood pressure control and angiotensin II receptor blockade on renal outcomes in the irbesartan diabetic ne-phropathy trial: clinical implications and limitations. J Am Soc Nephrol 2005; 16: 3027-337.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3027-3337
    • Pohl, M.A.1    Blumenthal, S.2    Cordonnier, D.J.3
  • 94
    • 43749112197 scopus 로고    scopus 로고
    • GUARD (Gauging Albuminuria Reduction With Lotrel in Diabetic Patients With Hypertension) Study Investigators: Effects of different ACE inhibitor combinations on albuminuria: Results of the GUARD study
    • Bakris GL, Toto RD, McCullough PA, Rocha R, Purkayastha D, Davis P; GUARD (Gauging Albuminuria Reduction With Lotrel in Diabetic Patients With Hypertension) Study Investigators: Effects of different ACE inhibitor combinations on albuminuria: results of the GUARD study. Kidney Int 2008; 73: 1303-1309.
    • (2008) Kidney Int , vol.73 , pp. 1303-1309
    • Bakris, G.L.1    Toto, R.D.2    McCullough, P.A.3    Rocha, R.4    Purkayastha, D.5    Davis, P.6
  • 95
    • 48349136426 scopus 로고    scopus 로고
    • Uzu T, Sawaguchi M, Maegawa H, Kashiwagi A: Impact of renin-an-giotensin system inhibition on microalbuminuria in type 2 diabe- tes: A post hoc analysis of the Shiga Microalbuminuria Reduction Trial (SMART)
    • Shiga Microalbuminuria Reduction Trial (SMART) Group
    • Shiga Microalbuminuria Reduction Trial (SMART) Group, Uzu T, Sawaguchi M, Maegawa H, Kashiwagi A: Impact of renin-an-giotensin system inhibition on microalbuminuria in type 2 diabe- tes: a post hoc analysis of the Shiga Microalbuminuria Reduction Trial (SMART). Hypertens Res 2008; 31: 1171-1176.
    • (2008) Hypertens Res , vol.31 , pp. 1171-1176
  • 96
    • 14044271544 scopus 로고    scopus 로고
    • NICE Combi Study Group: Controlled-re-lease nifedipine and candesartan low-dose combination therapy in patients with essential hypertension: The NICE Combi (Nifedipine and Candesartan Combination) Study
    • Hasebe N, Kikuchi K; NICE Combi Study Group: Controlled-re-lease nifedipine and candesartan low-dose combination therapy in patients with essential hypertension: the NICE Combi (Nifedipine and Candesartan Combination) Study. J Hypertens 2005; 23: 445- 453.
    • (2005) J Hypertens , vol.23 , pp. 445-453
    • Hasebe, N.1    Kikuchi, K.2
  • 97
    • 34250643958 scopus 로고    scopus 로고
    • Azelnidipine reduces urinary protein excretion and urinary liver-type fatty acid binding protein in patients with hypertensive chronic kidney disease
    • Nakamura T, Sugaya T, Kawagoe Y, Suzuki T, Ueda Y, Koide H, Inoue T, Node K: Azelnidipine reduces urinary protein excretion and urinary liver-type fatty acid binding protein in patients with hypertensive chronic kidney disease. Am J Med Sci 2007; 333: 321-326.
    • (2007) Am J Med Sci , vol.333 , pp. 321-326
    • Nakamura, T.1    Sugaya, T.2    Kawagoe, Y.3    Suzuki, T.4    Ueda, Y.5    Koide, H.6    Inoue, T.7    Node, K.8
  • 98
    • 48349097293 scopus 로고    scopus 로고
    • Combination therapy with renin-angio-tensin system inhibitors and the calcium channel blocker azelni-dipine decreases plasma inflammatory markers and urinary oxida-tive stress markers in patients with diabetic nephropathy
    • Ogawa S, Mori T, Ito S: Combination therapy with renin-angio-tensin system inhibitors and the calcium channel blocker azelni-dipine decreases plasma inflammatory markers and urinary oxida-tive stress markers in patients with diabetic nephropathy. Hyper-tens Res 2008; 31: 1147-1155.
    • (2008) Hyper-tens Res , vol.31 , pp. 1147-1155
    • Ogawa, S.1    Mori, T.2    Ito, S.3
  • 101
    • 70350045748 scopus 로고    scopus 로고
    • Comparison of the antiproteinuric effects of the calcium channel blockers benidipine and amlodipine administered in combination with angiotensin receptor blockers to hypertensive patients with stage 3-5 chronic kidney disease
    • Abe M, Okada K, Maruyama T, Maruyama N, Matsumoto K: Comparison of the antiproteinuric effects of the calcium channel blockers benidipine and amlodipine administered in combination with angiotensin receptor blockers to hypertensive patients with stage 3-5 chronic kidney disease. Hypertens Res 2009; 32: 270-275.
    • (2009) Hypertens Res , vol.32 , pp. 270-275
    • Abe, M.1    Okada, K.2    Maruyama, T.3    Maruyama, N.4    Matsumoto, K.5
  • 102
    • 40849130229 scopus 로고    scopus 로고
    • Calcium antagonists: Do they equally protect against kidney injury?
    • Hart P, Bakris GL: Calcium antagonists: Do they equally protect against kidney injury? Kidney Int 2008; 73: 795-796.
    • (2008) Kidney Int , vol.73 , pp. 795-796
    • Hart, P.1    Bakris, G.L.2
  • 103
    • 64849099219 scopus 로고    scopus 로고
    • Combined L-/T-type calcium channel blockers: Ready for prime time
    • Ge W, Ren J: Combined L-/T-type calcium channel blockers: ready for prime time. Hypertension 2009; 53: 592-594.
    • (2009) Hypertension , vol.53 , pp. 592-594
    • Ge, W.1    Ren, J.2


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