Renal afferent and efferent arteriolar dilation by nilvadipine: Studies in the isolated perfused hydronephrotic kidney

Journal of Cardiovascular Pharmacology

Volumn 33, Issue 2, 1999, Pages 243-247

  Ozawa, Yuri ^a   Hayashi, Koichi ^a   Nagahama, Takahiko ^a   Fujiwara, Keiji ^a   Wakino, Shu ^a   Saruta, Takao ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Afferent arteriole; Calcium antagonists; Efferent arteriole; Nilvadipine; Renal microcirculation

Indexed keywords

ANGIOTENSIN; NILVADIPINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; EFFERENT NERVE; HYDRONEPHROSIS; ISOLATED KIDNEY; KIDNEY PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE; VASODILATATION;

ANESTHESIA; ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; CALCIUM CHANNEL BLOCKERS; HYDRONEPHROSIS; MALE; MICROCIRCULATION; NIFEDIPINE; PERFUSION; RATS; RATS, WISTAR; RENAL ARTERY; VASOCONSTRICTION; VASODILATION;

EID: 0032935843     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199902000-00010     Document Type: Article

References (32)

1. Allison N, Dubb J, Alexander P, et al. Effect of nilvadipine on renal function in normal man [Abstract]. Fed Proc 1985;44:1638.
2. Carmines PK, Navar LG. Disparate effects of Ca channel blockade on afferent and efferent arteriolar responses to ANG II. Am J Physiol 1989;256:F1015-20.
3. Hayashi K, Nagahama T, Oka K, Epstein M, Saruta T. Disparate effects of calcium antagonists on renal microcirculation. Hypertens Res 1996;19:31-6.
4. Fleming JT, Parekh N, Steinhausen M. Calcium antagonists preferentially dilate preglomerular vessels of hydronephrotic kidney. Am J Physiol 1987;253:F1157-63.
5. Griffin KA, Picken MM, Bidani AK. Deleterious effects of calcium channel blockade on pressure transmission and glomerular injury in rat remnant kidneys. J Clin Invest 1995;96:793-800.
6. Saruta T, Kanno Y, Hayashi K, Konishi K. Antihypertensive agents and renal protection: calcium channel blockers. Kidney Int 1996;49(suppl 55):S52-6.
7. Arima S, Ito S, Omata K, Tsunoda K, Yaoita H, Abe K. Diverse effects of calcium antagonists on glomerular hemodynamics. Kidney Int 1996;49(suppl 55):S132-4.
8. Fujiwara K, Hayashi K, Kanno Y, Takenaka T, Saruta T. Renal protective effects of efonidipine hydrochloride in subtotally nephrectomized spontaneously hypertensive rats. Clin Exp Hypertens 1998;23:295-312.
9. Loutzenhiser R, Hayashi K, Epstein M. Atrial natriuretic peptide reverses afferent arteriolar vasoconstriction and potentiates efferent arteriolar vasoconstriction in the isolated perfused rat kidney. J Pharmacol Exp Ther 1988;246:522-8.
10. Loutzenhiser R, Hayashi K, Epstein M. Divergent effects of KCl-induced depolarization on afferent and efferent arterioles. Am J Physiol 1989;257:F561-4.
11. Steinhausen M, Snoei H, Parekh N, Baker R, Johnson PC. Hydronephrosis: a new method to visualize vas afferens, efferens, and glomerular network. Kidney Int 1983;23:794-806.
12. Epstein M, Flamenbaum W, Loutzenhiser R. Characterization of the renin-angiotensin system in the isolated perfused kidney. Renal Physiol 1980;2:244-56.
13. Hayashi K, Nagahama T, Oka K, Fujiwara K, Saruta T. Effects of insulin on rat renal microvessels: studies in the isolated perfused hydronephrotic kidney. Kidney Int 1997;51:1507-13.
14. Shudo C, Masuda Y, Sugita H. Renal protective effect of efonidipine hydrochloride (NZ-105): a new calcium antagonist in spontaneously hypertensive rats. Gen Pharmacol 1994;25:1567-75.
15. Fujimaki M, Nagase M, Uchida S. Long-term effect of manidipine on renal function and structure in uninephrectomized spontaneously hypertensive rats. Clin Exp Pharmacol Physiol 1997;27:506-12.
16. Takakura S, Furuichi Y, Mori J, et al. Effects of nilvadipine on the development of neurological deficits in stroke-prone spontaneously hypertensive rats. Stroke 1994;25:677-82.
17. Carmines PK, Perry MD, Hazelrig JB, Navar LG. Effects of preglomerular and postglomerular vascular resistance alterations on filtration fraction. Kidney Int 1987;31(suppl 20):S229-32.
18. Hayashi K, Epstein M, Loutzenhiser R. Pressure-induced vasoconstriction of renal microvessels in normotensive and hypertensive rats: studies in the isolated perfused hydronephrotic kidney. Circ Res 1989;65:1475-84.
19. Conger JD, Falk SA, Robinette JB. Angiotensin II-induced changes in smooth muscle calcium in rat arterioles. J Am Soc Nephrol 1993;3:1792-803.
20. Hayashi K, Saruta T, Epstein M. Renal hemodynamic effects of calcium antagonists. In: Epstein M, ed. Calcium antagonists and the kidney. 2nd ed. Philadelphia: Hanley & Belfus, 1998:393-411.
21. Loutzenhiser R, Chilton L, Trottier G. Membrane potential measurements in renal afferent and efferent arterioles: actions of angiotensin II. Am J Physiol 1997;273:F307-14.
22. 2+] in renal arterioles. Am J Physiol 1993;265:F677-85.
23. Brock TA, Alexander RW, Ekstein LS, Atkinson WJ, Gimbrone MA Jr. Angiotensin increases cytosolic free calcium in cultured vascular smooth muscle cells. Hypertension 1985;7(suppl I):I-105-9.
24. Takenaka T, Suzuki H, Kanno Y, et al. Cellular mechanisms mediating rat renal microvascular constriction by angiotensin II. J Clin Invest 1997;100:2107-14.
25. Nagahama T, Oka K, Hayashi K, Saruta T. Role of protein kinase C in angiotensin II-induced vasoconstriction of the renal microvasculature [Abstract]. J Am Soc Nephrol 1997;8:351A.
26. Lewis EJ, Hunsicker LG, Bain RP, Rohde RD. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N Engl J Med 1993;329:1456-62.
27. The GISEN Group (Gruppo Italiano di Studi Epidemiologici in Nefrologia). Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non-diabetic nephropathy. Lancet 1997;349:1857-63.
28. Anderson S, Rennke HG, Brenner BM. Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat. J Clin Invest 1986;77:1993-2000.
29. Kimura G, Imanishi M, Sanai T, et al. Intrarenal hemodynamics in patients with essential hypertension. Circ Res 1991;69:421-8.
30. Dworkin LD, Feiner HD, Parker M, Tolbert E. Effects of nifedipine and enalapril on glomerular structure and function in uninephrectomized SHR. Kidney Int 1991;39:1112-7.
31. Bauer JH, Reams GP. Renal protection with calcium antagonism in essential hypertension. Clin Invest Med 1989;12:300-4.
32. Maki DD, Ma JZ, Louis TA, Kasiske BL. Long-term effects of antihypertensive agents on proteinuria and renal function. Arch Intern Med 1995;155:1073-80.