Disparate effects of calcium antagonists on renal microcirculation

Hypertension Research - Clinical and Experimental

Volumn 19, Issue 1, 1996, Pages 31-36

  Hayashi, Koichi ^a   Nagahama, Takahiko ^a   Oka, Kiyoshi ^a   Epstein, Murray ^b,c   Saruta, Takao ^a  

^a KEIO UNIVERSITY   (Japan)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Afferent arteriole; Calcium antagonists; Efferent arteriole; Hypertension; Renal circulation

Indexed keywords

AMLODIPINE; ANGIOTENSIN; CALCIUM ANTAGONIST; CALCIUM CHANNEL; DIHYDROPYRIDINE DERIVATIVE; EFONIDIPINE; NICARDIPINE; NIFEDIPINE; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; DOSE RESPONSE; GLOMERULUS CAPILLARY; HYDRONEPHROSIS; HYPERTENSION; KIDNEY CIRCULATION; MALE; MICROCIRCULATION; NONHUMAN; RAT; VASOCONSTRICTION; VASODILATATION;

EID: 0029927951     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.19.31     Document Type: Article

References (29)

1. Murakami M, Murakami E, Takekoshi N, Tsuchiya M, Kin T: Antihypertensive effect of 4(-2′-nitro-phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonic acid dimethylester (nifedipine, Bay-a-1040), a new coronary dilator. Jpn Heart J 1972; 13: 128-135.
2. Epstein M: Calcium antagonists in the management of hypertension. Epstein M (eds): Calcium Antagonists in Clinical Medicine. Philadelphia, Hanley & Belfus, 1992, pp213.
3. Epstein M: Calcium antagonists and the kidney: implications for renal protection. Epstein M (eds): Calcium Antagonists in Clinical Medicine. Philadelphia, Hanley & Belfus, 1992, pp309.
4. Guyton AC: Kidneys and fluids in pressure regulation. Hypertension 1992; 19 (suppl I): I-2-I-8.
5. 2+ antagonists on isolated rabbit mesenteric resistance vessels as compared to rabbit aorta. Fleckenstein A, van Breemen C, Gross R, Hoffmeister F (eds): Cardiovascular Effects of Dihydropyridine-type Calcium Antagonists and Agonists. Berlin, Springer-Verlag, 1985, pp259-269.
6. Loutzenhiser R, Hayashi K, Epstein M: Calcium antagonists augment glomerular filtration rate of angiotensin II-vasoconstricted isolated perfused kidneys by dilating afferent but not efferent arterioles. J Cadiovasc Pharmacol 1988; 12: (Suppl 6) S149.
7. Carmines PK, Navar LG: Disparate effects of Ca channel blockade on afferent and efferent arteriolar responses to ANG II. Am J Physiol 1989; 256: F1015-F1020.
8. Fleming JT, Parekh N, Steinhausen M: Calcium antagonists preferentially dilate preglomerular vessels of hydronephrotic kidney. Am J Physiol 1987; 253: F1157-F1163.
9. Murakami K, Kimura G, Imanishi M, et al: Effect of manidipine, a new calcium antagonist, on intrarenal hemodynamics in essential hypertension. Blood Pressure 1992; 1 (Suppl 3): 114-118.
10. Loutzenhiser R, Hayashi K, Epstein M: Atrial natriuretic peptide reverses afferent arteriolar vasoconstriction and potentiates efferent arteriolar vasoconstriction in the isolated perfused rat kidney. J Pharmacol Exp Ther 1988; 246: 522-528.
11. Hayashi K, Epstein M, Loutzenhiser R: Pressure-induced vasoconstriction of renal microvessels in normotensive and hypertensive rats: studies in the isolated perfused hydronephrotic kidney. Circ Res 1989; 65: 1475-1484.
12. Loutzenhiser R, Epstein M, Hayashi K, Horton C: Direct visualization of effects of endothelin on the renal microvasculature. Am J Physiol 1990; 258: F61-F68.
13. Steinhausen M, Snoei H, Parekh N, Baker R, Johnson PC: Hydronephrosis: a new method to visualize vas afferens, efferens, and glomerular network. Kidney Int 1983; 23: 794-806.
14. Epstein M, Flamenbaum W, Loutzenhiser R: Characterization of the renin-angiotensin system in the isolated perfused rat kidney. Renal Physiol 1980; 2: 244-256.
15. Loutzenhiser R, Hayashi K, Epstein M: Divergent effects of KCl-induced depolarization on afferent and efferent arterioles. Am J Physiol 1989; 257: F561-F564.
16. 2+] in renal arterioles. Am J Physiol 1993; 265: F677-F685.
17. 2+ agonist in the split hydronephrotic kidney. Prog Appl Microcirc 1989; 14: 25-39.
18. Anderson S, Rennke H, Brenner BM: Nifedipine versus fosinopril in uninephrectomized diabetic rats. Kidney Int 1992; 41: 891-897.
19. Wenzel UO, Troschau G, Schoeppe W, Helmchen U, Schwietzer G: Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension. Hypertension 1992; 20: 233-241.
20. Mimran A, Insua A, Ribstein J, Monnier L, Bringer J, Mirouze J: Contrasting effects of captopril and nifedipine in normotensive patients with incipient diabetic nephropathy. J Hypertens 1988; 6: 919-923.
21. Tojo A, Kimura K, Matsuoka H, Sugimoto T: Effects of manidipine on the renal microcirculation in spontaneously hypertensive rats. J Cardiovasc Pharmacol 1992; 20: 895-899.
22. Yokoyama T, Masuda Y, Sakai T, Tanaka S, Tomita K: Effects of NZ-105, a new calcium antagonist, on renal function in anesthetized spontaneously hypertensive rats. J Cardiovasc Pharmacol 1992; 19: 851-856.
23. 2+movement in vascular smooth muscle cells. Jpn J Pharmacol 1990; 52: (Suppl I): 82.
24. ter Wee PM, De Micheli AG, Epstein M: Effects of calcium antagonists on renal hemodynamics and progression of non-diabetic chronic renal disease. Arch Intern Med 1994; 154: 1185-1202.
25. Dworkin LD, Benstein JA, Parker M, Tolbert E, Feiner HD: Calcium antagonists and converting enzyme inhibitors reduce renal injury by different mechanisms. Kidney Int 1993; 43: 808-814.
26. Kanno Y, Suzuki H, Okada H, Okada H, Saruta T: Renal protective effects of amlodipine on partially nephrectomized spontaneously hypertensive rats fed a high-salt diet. J Cardiovasc Pharmacol 1994; 23: 480-484.
27. Demarie BK, Bakris CL: Different effects of calcium antagonists on proteinuria in diabetic man. Ann Intern Med 1990; 112: 707-708.
28. Shudo C, Masuda Y, Sugita H, Tanaka S, Tomita K: Beneficial effect of efonidipine hydrochloride (NZ-105) on proteinuria in aged spontaneously hypertensive rats (SHR). Pharm Sci 1995; 1: 333-335.
29. Shudo C, Masuda Y, Sugita H, et al: Renal protective effect of efonidipine hydrochloride (NZ-105), a nesv calcium antagonist, in spontaneously hypertensive rats. Gen Pharmacol 1994; 25: 1567-1575.