Nifedipine indirectly upregulates superoxide dismutase expression in endothelial cells via vascular smooth muscle cell-dependent pathways

Circulation

Volumn 106, Issue 3, 2002, Pages 356-361

  Fukuo, Keisuke ^a   Yang, Jin ^a   Yasuda, Osamu ^a   Mogi, Masaki ^a   Suhara, Toshimitsu ^a   Sato, Naoyuki ^a   Suzuki, Takashi ^a   Morimoto, Shigeto ^a   Ogihara, Toshio ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Bradykinin; Calcium; Endothelium; Muscle, Smooth; Nitric oxide

Indexed keywords

AMLODIPINE; ANTISENSE OLIGODEOXYNUCLEOTIDE; BRADYKININ RECEPTOR; ICATIBANT; NEUTRALIZING ANTIBODY; NIFEDIPINE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; VASCULOTROPIN;

ARTICLE; COCULTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; CALCIUM CHANNEL BLOCKERS; CELL COMMUNICATION; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; HUMANS; LYMPHOKINES; MALE; MUSCLE, SMOOTH, VASCULAR; NIFEDIPINE; NITRIC OXIDE; RATS; RATS, WISTAR; RECEPTORS, BRADYKININ; SUPEROXIDE DISMUTASE; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0037118682     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000021924.02006.BA     Document Type: Article

References (24)

1. Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
2. Extracellular superoxide dismutase in vessels and airways of humans and baboons
3. Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation
4. SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
5. Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbit by treatment with the calcium blocker PN200110
6. Nifedipine improves endothelial function in hypercholesterolemia, independently of an effect on blood pressure or plasma lipids
7. Antioxidant activity of calcium channel blocking drugs
8. Pattern of superoxide dismutase enzymatic activity and RNA changes in rat heart ventricles after myocardial infarction
9. Detection and imaging of nitric oxide with novel fluorescent indicators: Diaminofluoresceins
10. Induction of manganese superoxide dismutase in rat cardiac myocytes increases tolerance to hypoxia 24 hours after preconditioning
11. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
12. Effect of amlodipine on morbidity and mortality in severe chronic heart failure
13. Morbidity and mortality in patients randomized to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT)
14. Normalization of abnormal coronary vasomotion by calcium antagonists in patients with hypertension
15. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease
16. Risk of thrombosis in human atherosclerotic plaques: Role of extracellular lipid, macrophage, and smooth muscle cell content
17. Direct in situ measurement of nitric oxide in mesenteric resistance arteries: Increased decomposition by superoxide in hypertension
18. Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: Role of enhanced vascular superoxide production
19. Superoxide production and reactive oxygen species signaling by endothelial nitric-oxide synthase
20. Effect of native and oxidized low-density lipoprotein on endothelial nitric oxide and superoxide production: Key role of L-arginine availability
21. Interaction of 1,4 dihydropyridine calcium channel antagonists with biological membranes: Lipid bilayer partitioning could occur before drug binding to receptors
22. Amlodipine releases nitric oxide from canine coronary microvessels: An unexpected mechanism of action of a calcium channel-blocking agent
23. Human airway smooth muscle cells secrete vascular endothelial growth factor: Upregulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism
24. Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training