Contrasting Effects of Selective T- and L-Type Calcium Channel Blockade on Glomerular Damage in DOCA Hypertensive Rats

Hypertension

Volumn 34, Issue 4, 1999, Pages 673-678

  Karam, Habib ^a   Clozel, Jean Paul ^a   Bruneval, Patrick ^a   Gonzalez, Marie Françoise ^a   Ménard, Joël ^a  

^a HÔPITAL BROUSSAIS   (France)

Author keywords

Amlodipine; Calcium channels; Hypertension, experimental; Kidney; Mibefradil; Rats

Indexed keywords

AMLODIPINE; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; ENALAPRIL; KIDNEY RENIN; MIBEFRADIL;

ANIMAL TISSUE; ARTICLE; DRUG SELECTIVITY; HYPERTENSION; KIDNEY INJURY; MALE; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEINURIA; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYSTOLIC BLOOD PRESSURE;

AMLODIPINE; ANALYSIS OF VARIANCE; ANIMALS; BLOOD PRESSURE; BODY WEIGHT; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CORONARY CIRCULATION; DESOXYCORTICOSTERONE; HEMODYNAMIC PROCESSES; HYPERTENSION; KIDNEY GLOMERULUS; MALE; MIBEFRADIL; ORGAN SIZE; RATS; RATS, WISTAR; RENIN;

EID: 0032701555     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/01.HYP.34.4.673     Document Type: Article

References (25)

1. Bernink PJLM, Prager G, Schelling A, Kobrin I. Antihypertensive properties of the novel calcium antagonist mibefradil (Ro 40-5967): a new generation of calcium antagonists? Hypertension. 1996;27:426-432.
2. Ménard J, Karam H, Véniant M, Heudes D, Bruneval P, Clozel J-P. Effects of calcium blockade on end-organ damage in experimental hypertension. J Hypertens. 1997;15(suppl 3):S19-S30.
3. Dworkin LD, Tolbert E, Recht PA, Hersch JC, Feiner H, Levin RI. Effects of amlodipine on glomerular filtration, growth, and injury in experimental hypertension. Hypertension. 1996;27:245-250.
4. Wagner C, Kramer BK, Hinder M, Kieninger M, Kurtz A. T-type, and L-type calcium channel blockers exert opposite effects on renin secretion and renin gene expression in conscious rats. Br J Pharmacol. 1998;124:579-585.
5. Ménard J, Catt KJ. Measurement of renin activity, concentration and substrate in rat plasma by radioimmunoassay of angiotensin I. Endocrinology. 1972;90:422-430.
6. Clozel JP, Osterrieder W, Kleinbloesem CH, Welker HA, Schläppi B, Tudor R, Hefti F, Schmitt R, Eggers H. Ro 40-5967: a new nondihydropyridine calcium antagonist. Cardiovasc Drugs Rev. 1991;9:4-17.
7. Véniant M, Clozel JP, Hess P, Wolfgang R. Hemodynamic profile of Ro 40-5967 in conscious rats: comparison with diltiazem, verapamil and amlodipine. J Cardiovasc Pharmacol. 1991;18:S55-S58.
8. 2+ channels by Ro 40-5967. Circ Res. 1994;75:144-148.
9. Selye H, Hall CE, Rowley EM. Malignant hypertension produced by treatment with deoxycorticosterone acetate and sodium chloride. Can Med Assoc J. 1943;49:88-92.
10. Hamlyn JM, Blaustein MP. Sodium chloride, extracellular fluid volume, and blood pressure regulation. Am J Physiol. 1986;251:F563-F575.
11. Ueno Y. Mohara O, Brosnihan KB, Ferrario CM. Characteristics of hormonal and neurogenic mechanisms of deoxycorticosterone-induced hypertension. Hypertension. 1988;11(suppl 1):I172-I177.
12. Gavras H, Brunner HR, Laragh JH, Vaughan ED, Koss M, Cote LJ, Gavras I. Malignant hypertension resulting from deoxycorticosterone acetate and salt excess. Circ Res. 1975;63:300-309.
13. Dworkin LD, Feiner HD, Randazzo J. Glomerular hypertension and injury in deoxycorticosterone-salt rats on antihypertensive therapy. Kidney Int. 1987;31:718-724.
14. Karam H, Heudes D, Hess P, Gonzales M-F, Löffler B-M, Clozel M, Clozel J-P. Respective role of humoral factors and blood pressure in cardiac remodeling of DOCA hypertensive rats. Cardiovasc Res. 1996;31:287-295.
15. Churchill PC. Calcium channel antagonists and renin release. Am J Nephrol. 1987;7:32-38.
16. Osswald H, Weinheimer G, Kapp JF. Renal actions of calcium channel antagonists. J Neural Transm Suppl. 1990;31:39-53.
17. Cappucio FP, Markandu ND, Sagnella GA, Singer DR, Buckley MG, Miller MA, MacGregor GA. Effects of amlodipine on urinary sodium excretion, renin-angiotensin-aldosterone system, atrial peptide and blood pressure in essential hypertension. J Hum Hypertens. 1991;5:115-119.
18. Schricker K, Hamann M, Macher A, Krämer BK, Kaissling B, Kurtz A. Effect of amlodipine on renin secretion and renin gene expression in rats. Br J Pharmacol. 1996;119:744-750.
19. Villarreal FJ, Kim NN, Ungab GD, Printz MP, Dillmann WH. Identification of functional angiotensin II receptors on rat cardiac fibroblasts. Circulation. 1993;88:2849-2861.
20. Brilla CG, Zhou G, Matsubara L, Weber KT. Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone. J Mol Cell Cardiol. 1994;26:809-820.
21. Brilla CG, Pick R, Tan LB, Janicki JS, Weber KT. Remodeling of the rat right and left ventricles in experimental hypertension. Circ Res. 1990;67:1355-1364.
22. Scholz H, Kurtz A. Differential regulation of cytosolic calcium between afferent arteriolar smooth muscle cells from mouse kidney. Pflügers Arch. 1996;431:46-51.
23. Hall JE. Control of sodium excretion by angiotensin II: intra-renal mechanisms and blood pressure regulation. Am J Physiol. 1986;250:R960-R972.
24. 2+ channel gene family. Circ Res. 1998;83:103-109.
25. Hackenthal E, Paul M, Ganten D, Taugner R. Morphology, physiology and molecular biology of renin secretion. Physiol Rev. 1990;70:1067-1116.