메뉴 건너뛰기




Volumn 1, Issue , 2010, Pages

Requirement of ATM-dependent pathway for the repair of a subset of DNA double strand breaks created by restriction endonucleases

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; ATM PROTEIN; ENDONUCLEASE; SERINE;

EID: 78249273420     PISSN: None     EISSN: 20419414     Source Type: Journal    
DOI: 10.1186/2041-9414-1-4     Document Type: Article
Times cited : (5)

References (55)
  • 1
    • 33747889722 scopus 로고    scopus 로고
    • Role of non-homologous end joining (NHEJ) in maintaining genomic integrity
    • 10.1016/j.dnarep.2006.05.026, 16822724
    • Burma S, Chen BP, Chen DJ. Role of non-homologous end joining (NHEJ) in maintaining genomic integrity. DNA Repair 2006, 5:1042-1048. 10.1016/j.dnarep.2006.05.026, 16822724.
    • (2006) DNA Repair , vol.5 , pp. 1042-1048
    • Burma, S.1    Chen, B.P.2    Chen, D.J.3
  • 2
    • 33747889217 scopus 로고    scopus 로고
    • Differential usage of non-homologous end-joining and homologous recombination in double strand break repair
    • 10.1016/j.dnarep.2006.05.022, 16807135
    • Sonoda E, Hochegger H, Saberi A, Taniguchi Y, Takeda S. Differential usage of non-homologous end-joining and homologous recombination in double strand break repair. DNA Repair 2006, 5:1021-1029. 10.1016/j.dnarep.2006.05.022, 16807135.
    • (2006) DNA Repair , vol.5 , pp. 1021-1029
    • Sonoda, E.1    Hochegger, H.2    Saberi, A.3    Taniguchi, Y.4    Takeda, S.5
  • 3
    • 33845604556 scopus 로고    scopus 로고
    • DNA double-strand break repair: all's well that ends well
    • 10.1146/annurev.genet.40.110405.090451, 16895466
    • Wyman C, Kanaar R. DNA double-strand break repair: all's well that ends well. Annu Rev Genet 2006, 40:363-383. 10.1146/annurev.genet.40.110405.090451, 16895466.
    • (2006) Annu Rev Genet , vol.40 , pp. 363-383
    • Wyman, C.1    Kanaar, R.2
  • 4
    • 72049089840 scopus 로고    scopus 로고
    • Cellular radiosensitivity: How much better do we understand it?
    • 10.3109/09553000903261263, 19995233
    • Jeggo P, Lavin MF. Cellular radiosensitivity: How much better do we understand it?. Int J Radiat Biol 2009, 85:1061-1081. 10.3109/09553000903261263, 19995233.
    • (2009) Int J Radiat Biol , vol.85 , pp. 1061-1081
    • Jeggo, P.1    Lavin, M.F.2
  • 5
    • 68249125048 scopus 로고    scopus 로고
    • Choreorgaphy of recombination proteins during the DNA damage response
    • 10.1016/j.dnarep.2009.04.007, 19473884
    • Lisby M, Rothstein R. Choreorgaphy of recombination proteins during the DNA damage response. DNA Repair 2009, 8:1068-1076. 10.1016/j.dnarep.2009.04.007, 19473884.
    • (2009) DNA Repair , vol.8 , pp. 1068-1076
    • Lisby, M.1    Rothstein, R.2
  • 6
    • 59849089955 scopus 로고    scopus 로고
    • Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
    • 10.1042/BJ20080413, 19133841
    • Mahaney BL, Meek K, Lees-Miller SP. Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem J 2009, 417:639-650. 10.1042/BJ20080413, 19133841.
    • (2009) Biochem J , vol.417 , pp. 639-650
    • Mahaney, B.L.1    Meek, K.2    Lees-Miller, S.P.3
  • 7
    • 33747882881 scopus 로고    scopus 로고
    • DNA double-strand break repair and chromosome translocations
    • 10.1016/j.dnarep.2006.05.029, 16798112
    • Agarwal S, Tafel AA, Kanaar R. DNA double-strand break repair and chromosome translocations. DNA Repair 2006, 5:1075-1081. 10.1016/j.dnarep.2006.05.029, 16798112.
    • (2006) DNA Repair , vol.5 , pp. 1075-1081
    • Agarwal, S.1    Tafel, A.A.2    Kanaar, R.3
  • 8
    • 33748173811 scopus 로고    scopus 로고
    • Contribution of DNA repair and cell cycle checkpoint arrest to the maintainance of genomic stability
    • 10.1016/j.dnarep.2006.05.011, 16797253
    • Jeggo P, Lobrich M. Contribution of DNA repair and cell cycle checkpoint arrest to the maintainance of genomic stability. DNA Repair 2006, 5:1192-1198. 10.1016/j.dnarep.2006.05.011, 16797253.
    • (2006) DNA Repair , vol.5 , pp. 1192-1198
    • Jeggo, P.1    Lobrich, M.2
  • 9
    • 52149095466 scopus 로고    scopus 로고
    • Induction of chromosomal translocations in mouse and human cells using site-specific endonucleases
    • 10.1093/jncimonographs/lgn009, 18647997
    • Weinstock DM, Brunet E, Jasin M. Induction of chromosomal translocations in mouse and human cells using site-specific endonucleases. J Natl Cancer Inst Monogr 2008, 39:20-24. 10.1093/jncimonographs/lgn009, 18647997.
    • (2008) J Natl Cancer Inst Monogr , vol.39 , pp. 20-24
    • Weinstock, D.M.1    Brunet, E.2    Jasin, M.3
  • 10
    • 36949005417 scopus 로고    scopus 로고
    • DNA damage signalling guards against activated oncogenes and tumour progression
    • 10.1038/sj.onc.1210881, 18066090
    • Bartek J, Bartkova J, Lukas J. DNA damage signalling guards against activated oncogenes and tumour progression. Oncogene 2007, 26:7773-7779. 10.1038/sj.onc.1210881, 18066090.
    • (2007) Oncogene , vol.26 , pp. 7773-7779
    • Bartek, J.1    Bartkova, J.2    Lukas, J.3
  • 11
    • 36749022214 scopus 로고    scopus 로고
    • The DNA damage response: ten years after
    • 10.1016/j.molcel.2007.11.015, 18082599
    • Harper JW, Elledge SJ. The DNA damage response: ten years after. Mol Cell 2007, 28:739-745. 10.1016/j.molcel.2007.11.015, 18082599.
    • (2007) Mol Cell , vol.28 , pp. 739-745
    • Harper, J.W.1    Elledge, S.J.2
  • 12
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related proteins kinases: safeguarding genome integrity
    • 10.1038/nrc1011, 12612651
    • Shiloh Y. ATM and related proteins kinases: safeguarding genome integrity. Nat Rev Cancer 2003, 3:155-168. 10.1038/nrc1011, 12612651.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 13
    • 33746407124 scopus 로고    scopus 로고
    • The ATM-dependent DNA damage signaling pathway
    • 10.1101/sqb.2005.70.002, 16869743
    • Kitagawa R, Kastan MB. The ATM-dependent DNA damage signaling pathway. Cold Spring Harb Symp Quant Biol 2005, 70:99-109. 10.1101/sqb.2005.70.002, 16869743.
    • (2005) Cold Spring Harb Symp Quant Biol , vol.70 , pp. 99-109
    • Kitagawa, R.1    Kastan, M.B.2
  • 14
    • 52449114574 scopus 로고    scopus 로고
    • Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
    • 10.1038/nrm2514, 18813293
    • Lavin MF. Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer. Nat Rev Mol Cell Biol 2008, 9:759-769. 10.1038/nrm2514, 18813293.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 759-769
    • Lavin, M.F.1
  • 15
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • 10.1038/nature01368, 12556884
    • Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003, 421:499-506. 10.1038/nature01368, 12556884.
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 16
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • 10.1038/nature08467, 19847258
    • Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature 2009, 461:1071-1078. 10.1038/nature08467, 19847258.
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 17
    • 67749104769 scopus 로고    scopus 로고
    • The DNA-damage response: new molecular insights and new approaches to cancer therapy
    • 10.1042/BST0370483, 19442242
    • Jackson SP. The DNA-damage response: new molecular insights and new approaches to cancer therapy. Biochem Soc Trans 2009, 37:483-494. 10.1042/BST0370483, 19442242.
    • (2009) Biochem Soc Trans , vol.37 , pp. 483-494
    • Jackson, S.P.1
  • 18
    • 67651125091 scopus 로고    scopus 로고
    • Clinical radiation sensitivity with DNA repair disorders: an overview
    • Pollard JM, Gatti RA. Clinical radiation sensitivity with DNA repair disorders: an overview. Int J Radiat Oncol Biol Phys 2009, 74:1323-1331.
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , pp. 1323-1331
    • Pollard, J.M.1    Gatti, R.A.2
  • 19
    • 0030750923 scopus 로고    scopus 로고
    • Hypersensitivity of ataxia-telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks
    • 10.1080/095530097143266, 9298107
    • Foray N, Priestley A, Alsbeih G, Badie C, Capulas EP, Arlett CF, Malaise EP. Hypersensitivity of ataxia-telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks. Int J Radiat Biol 1997, 72:271-283. 10.1080/095530097143266, 9298107.
    • (1997) Int J Radiat Biol , vol.72 , pp. 271-283
    • Foray, N.1    Priestley, A.2    Alsbeih, G.3    Badie, C.4    Capulas, E.P.5    Arlett, C.F.6    Malaise, E.P.7
  • 20
    • 0032404350 scopus 로고    scopus 로고
    • Splitting the ATM: distinct repair and checkpoint defects in ataxia-telangiectasia
    • 10.1016/S0168-9525(98)01511-X, 9724963
    • Jeggo PA, Carr AM, Lehmann AR. Splitting the ATM: distinct repair and checkpoint defects in ataxia-telangiectasia. Trends Genet 1998, 14:312-316. 10.1016/S0168-9525(98)01511-X, 9724963.
    • (1998) Trends Genet , vol.14 , pp. 312-316
    • Jeggo, P.A.1    Carr, A.M.2    Lehmann, A.R.3
  • 21
    • 1642556817 scopus 로고    scopus 로고
    • A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity
    • 10.1158/0008-5472.CAN-03-2384, 14744762
    • Kuhne M, Riballo E, Rief M, Rothkamm K, Jeggo PA, Lobrich M. A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Res 2004, 64:500-508. 10.1158/0008-5472.CAN-03-2384, 14744762.
    • (2004) Cancer Res , vol.64 , pp. 500-508
    • Kuhne, M.1    Riballo, E.2    Rief, M.3    Rothkamm, K.4    Jeggo, P.A.5    Lobrich, M.6
  • 23
    • 25444502657 scopus 로고    scopus 로고
    • Artemis links ATM to double strand break rejoining
    • Jeggo PA, Lobrich M. Artemis links ATM to double strand break rejoining. Cell Cycle 2005, 4:359-362.
    • (2005) Cell Cycle , vol.4 , pp. 359-362
    • Jeggo, P.A.1    Lobrich, M.2
  • 24
    • 20644471358 scopus 로고    scopus 로고
    • Harmonising the response to DSBs: a new string in the ATM bow
    • 10.1016/j.dnarep.2004.12.008, 15978533
    • Lobrich M, Jeggo PA. Harmonising the response to DSBs: a new string in the ATM bow. DNA Repair 2005, 4:749-759. 10.1016/j.dnarep.2004.12.008, 15978533.
    • (2005) DNA Repair , vol.4 , pp. 749-759
    • Lobrich, M.1    Jeggo, P.A.2
  • 25
    • 34047153762 scopus 로고    scopus 로고
    • Functions and regulation of human Artemis in double strand break repair
    • 10.1002/jcb.21226, 17211852
    • Dahm K. Functions and regulation of human Artemis in double strand break repair. J Cell Biochem 2007, 100:1346-1351. 10.1002/jcb.21226, 17211852.
    • (2007) J Cell Biochem , vol.100 , pp. 1346-1351
    • Dahm, K.1
  • 27
    • 4744373121 scopus 로고    scopus 로고
    • Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response
    • 10.1128/MCB.24.20.9207-9220.2004, 517881, 15456891
    • Zhang X, Succi J, Feng Z, Prithivirasingh S, Story MD, Legersky R. Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Mol Cell Biol 2004, 24:9207-9220. 10.1128/MCB.24.20.9207-9220.2004, 517881, 15456891.
    • (2004) Mol Cell Biol , vol.24 , pp. 9207-9220
    • Zhang, X.1    Succi, J.2    Feng, Z.3    Prithivirasingh, S.4    Story, M.D.5    Legersky, R.6
  • 28
    • 47349107760 scopus 로고    scopus 로고
    • ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
    • 10.1016/j.molcel.2008.05.017, 18657500
    • Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, Lobrich M, Jeggo PA. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell 2008, 31:167-177. 10.1016/j.molcel.2008.05.017, 18657500.
    • (2008) Mol Cell , vol.31 , pp. 167-177
    • Goodarzi, A.A.1    Noon, A.T.2    Deckbar, D.3    Ziv, Y.4    Shiloh, Y.5    Lobrich, M.6    Jeggo, P.A.7
  • 30
    • 66149111681 scopus 로고    scopus 로고
    • Revisiting the role of heterochromatin protein 1 in DNA repair
    • 10.1083/jcb.200904033, 2711565, 19451270
    • Ball AR, Yokomori K. Revisiting the role of heterochromatin protein 1 in DNA repair. J Cell Biol 2009, 185:573-575. 10.1083/jcb.200904033, 2711565, 19451270.
    • (2009) J Cell Biol , vol.185 , pp. 573-575
    • Ball, A.R.1    Yokomori, K.2
  • 31
    • 42249102663 scopus 로고    scopus 로고
    • Gamma-H2AX foci form preferentially in euchromatin after ionising-radiation
    • 10.1371/journal.pone.0001057, 10.1371/journal.pone.0001057, 2020439, 17957241
    • Cowell IG, Sunter NJ, Singh PB, Austin CA, Durkacz BW, Tilby MJ. Gamma-H2AX foci form preferentially in euchromatin after ionising-radiation. PLoS ONE 2007, 2:e1057. 10.1371/journal.pone.0001057, 10.1371/journal.pone.0001057, 2020439, 17957241.
    • (2007) PLoS ONE , vol.2
    • Cowell, I.G.1    Sunter, N.J.2    Singh, P.B.3    Austin, C.A.4    Durkacz, B.W.5    Tilby, M.J.6
  • 33
    • 67749093497 scopus 로고    scopus 로고
    • The impact of heterochromatin on DSB repair
    • 10.1042/BST0370569, 19442252
    • Goodarzi AA, Noon AT, Jeggo PA. The impact of heterochromatin on DSB repair. Biochem Soc Trans 2009, 37:569-576. 10.1042/BST0370569, 19442252.
    • (2009) Biochem Soc Trans , vol.37 , pp. 569-576
    • Goodarzi, A.A.1    Noon, A.T.2    Jeggo, P.A.3
  • 34
    • 44449136965 scopus 로고    scopus 로고
    • HP1-β mobilization promotes chromatin changes that initiate the DNA damage response
    • 10.1038/nature06875, 18438399
    • Ayoub N, Jeyasekharan AD, Bernal JA, Venkitaraman AR. HP1-β mobilization promotes chromatin changes that initiate the DNA damage response. Nature 2008, 453:682-686. 10.1038/nature06875, 18438399.
    • (2008) Nature , vol.453 , pp. 682-686
    • Ayoub, N.1    Jeyasekharan, A.D.2    Bernal, J.A.3    Venkitaraman, A.R.4
  • 35
    • 48349097917 scopus 로고    scopus 로고
    • ATM breaks into heterochromatin
    • 10.1016/j.molcel.2008.07.004, 18691960
    • Fernadez-Capetillo O, Nussenzweig A. ATM breaks into heterochromatin. Mol Cell 2008, 31:303-304. 10.1016/j.molcel.2008.07.004, 18691960.
    • (2008) Mol Cell , vol.31 , pp. 303-304
    • Fernadez-Capetillo, O.1    Nussenzweig, A.2
  • 36
    • 0024504602 scopus 로고
    • Cell electroporation is a highly efficient method for introducing restriction endonucleases into cells
    • 10.1016/0165-7992(89)90032-8, 2536473
    • Winegar RA, Phillips JW, Youngblom JH, Morgan WF. Cell electroporation is a highly efficient method for introducing restriction endonucleases into cells. Mutat Res 1989, 225:49-53. 10.1016/0165-7992(89)90032-8, 2536473.
    • (1989) Mutat Res , vol.225 , pp. 49-53
    • Winegar, R.A.1    Phillips, J.W.2    Youngblom, J.H.3    Morgan, W.F.4
  • 37
    • 0027435175 scopus 로고
    • Response of ataxia telangiectasia cells to restriction endonuclease induced DNA double-strand breaks: I. Cytogenetic characterization
    • 10.1093/mutage/8.6.503, 8133779
    • Liu N, Bryant PE. Response of ataxia telangiectasia cells to restriction endonuclease induced DNA double-strand breaks: I. Cytogenetic characterization. Mutagenesis 1993, 8:503-510. 10.1093/mutage/8.6.503, 8133779.
    • (1993) Mutagenesis , vol.8 , pp. 503-510
    • Liu, N.1    Bryant, P.E.2
  • 38
    • 0028564893 scopus 로고
    • Enhanced chromosomal response of ataxia-telangiectasia cells to specific types of DNA double-strand breaks
    • Liu N, Bryant PE. Enhanced chromosomal response of ataxia-telangiectasia cells to specific types of DNA double-strand breaks. Int J Radiat Biol 1994, 66(Supple 6):115-121.
    • (1994) Int J Radiat Biol , vol.66 , Issue.SUPPL 6 , pp. 115-121
    • Liu, N.1    Bryant, P.E.2
  • 39
    • 0023815374 scopus 로고
    • Use of restriction endonucleases to study relationships between DNA double-strand breaks, chromosomal aberrations and other end-points in mammalian cells
    • 10.1080/09553008814552291, 2903886
    • Bryant PE. Use of restriction endonucleases to study relationships between DNA double-strand breaks, chromosomal aberrations and other end-points in mammalian cells. Int J Radiat Biol 1988, 54:869-890. 10.1080/09553008814552291, 2903886.
    • (1988) Int J Radiat Biol , vol.54 , pp. 869-890
    • Bryant, P.E.1
  • 40
    • 0027462474 scopus 로고
    • Restriction-endonuclease-induced DNA double-strand breaks and chromosomal aberrations in mammalian cells
    • 10.1016/0165-1218(93)90105-M, 7683096
    • Bryant PE, Johnston PJ. Restriction-endonuclease-induced DNA double-strand breaks and chromosomal aberrations in mammalian cells. Mutat Res 1993, 299:289-296. 10.1016/0165-1218(93)90105-M, 7683096.
    • (1993) Mutat Res , vol.299 , pp. 289-296
    • Bryant, P.E.1    Johnston, P.J.2
  • 41
    • 0028934355 scopus 로고
    • Chromosome damage induced by combined treatments with restriction endonucleases introduced into CHO cells by single or double electroporation
    • Ortiz T, Pinero J, Cortes F. Chromosome damage induced by combined treatments with restriction endonucleases introduced into CHO cells by single or double electroporation. Mutat Res 1995, 327:161-169.
    • (1995) Mutat Res , vol.327 , pp. 161-169
    • Ortiz, T.1    Pinero, J.2    Cortes, F.3
  • 42
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • 10.1083/jcb.146.5.905, 2169482, 10477747
    • Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 1999, 146:905-915. 10.1083/jcb.146.5.905, 2169482, 10477747.
    • (1999) J Cell Biol , vol.146 , pp. 905-915
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 43
    • 16644392782 scopus 로고    scopus 로고
    • Detection of DNA damage in individual cells by analysis of histone H2AX phosphorylation
    • full_text, 15603433
    • Olive PL. Detection of DNA damage in individual cells by analysis of histone H2AX phosphorylation. Methods Cell Biol 2004, 75:355-373. full_text, 15603433.
    • (2004) Methods Cell Biol , vol.75 , pp. 355-373
    • Olive, P.L.1
  • 44
    • 70349308060 scopus 로고    scopus 로고
    • 53 BP1: function and mechanism of focal recruitment
    • 10.1042/BST0370897, 19614615
    • FitzGerald JE, Grenon M, Lowndes NF. 53 BP1: function and mechanism of focal recruitment. Biochem Soc Trans 2009, 37:897-904. 10.1042/BST0370897, 19614615.
    • (2009) Biochem Soc Trans , vol.37 , pp. 897-904
    • FitzGerald, J.E.1    Grenon, M.2    Lowndes, N.F.3
  • 45
    • 3242880238 scopus 로고    scopus 로고
    • H2AX: the histone guardian of the genome
    • 10.1016/j.dnarep.2004.03.024, 15279782
    • Fernandez-Capetillo O, Lee A, Nussenzweig M, Nussenzweig A. H2AX: the histone guardian of the genome. DNA Repair 2004, 3:959-967. 10.1016/j.dnarep.2004.03.024, 15279782.
    • (2004) DNA Repair , vol.3 , pp. 959-967
    • Fernandez-Capetillo, O.1    Lee, A.2    Nussenzweig, M.3    Nussenzweig, A.4
  • 47
    • 55249116558 scopus 로고    scopus 로고
    • Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
    • 10.1093/nar/gkn550, 2553572, 18772227
    • Kinner A, Wu W, Staudt C, Iliakis G. Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin. Nucleic Acids Res 2008, 36:5678-5694. 10.1093/nar/gkn550, 2553572, 18772227.
    • (2008) Nucleic Acids Res , vol.36 , pp. 5678-5694
    • Kinner, A.1    Wu, W.2    Staudt, C.3    Iliakis, G.4
  • 48
    • 9744271049 scopus 로고    scopus 로고
    • Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
    • 10.1158/0008-5472.CAN-04-2727, 15604286
    • Hickson I, Zhao Y, Richardson CJ, Green SJ, Martin NM, Orr AI, Reaper PM, Jackson SP, Curtin NJ, Smith GC. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res 2004, 64:9152-9159. 10.1158/0008-5472.CAN-04-2727, 15604286.
    • (2004) Cancer Res , vol.64 , pp. 9152-9159
    • Hickson, I.1    Zhao, Y.2    Richardson, C.J.3    Green, S.J.4    Martin, N.M.5    Orr, A.I.6    Reaper, P.M.7    Jackson, S.P.8    Curtin, N.J.9    Smith, G.C.10
  • 50
    • 64549100748 scopus 로고    scopus 로고
    • Signatures of DNA double strand breaks produced in irradiated G1 and G2 cells persist into mitosis
    • 10.1002/jcp.21726, 19206160
    • Kato TA, Okayasu R, Bedford JS. Signatures of DNA double strand breaks produced in irradiated G1 and G2 cells persist into mitosis. J Cell Physiol 2009, 219:760-765. 10.1002/jcp.21726, 19206160.
    • (2009) J Cell Physiol , vol.219 , pp. 760-765
    • Kato, T.A.1    Okayasu, R.2    Bedford, J.S.3
  • 52
    • 45549099011 scopus 로고    scopus 로고
    • Coordinate 5' and 3' endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase
    • 10.1093/nar/gkn205, 2425473, 18440975
    • Yannone SM, Khan IS, Zhou RZ, Zhou T, Valerie K, Povirk LF. Coordinate 5' and 3' endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase. Nucleic Acids Res 2008, 36:3354-3365. 10.1093/nar/gkn205, 2425473, 18440975.
    • (2008) Nucleic Acids Res , vol.36 , pp. 3354-3365
    • Yannone, S.M.1    Khan, I.S.2    Zhou, R.Z.3    Zhou, T.4    Valerie, K.5    Povirk, L.F.6
  • 54
    • 33646437364 scopus 로고    scopus 로고
    • Qualitative and quantitative analysis of phosphorylated ATM foci induced by low dose ionizing radiation
    • 10.1667/RR3542.1, 16669703
    • Suzuki K, Okada H, Yamauchi M, Oka Y, Kodama S, Watanabe M. Qualitative and quantitative analysis of phosphorylated ATM foci induced by low dose ionizing radiation. Radiat Res 2006, 165:499-504. 10.1667/RR3542.1, 16669703.
    • (2006) Radiat Res , vol.165 , pp. 499-504
    • Suzuki, K.1    Okada, H.2    Yamauchi, M.3    Oka, Y.4    Kodama, S.5    Watanabe, M.6
  • 55
    • 0027085881 scopus 로고
    • Effect of multiple irradiation with low doses of gamma-rays on morphological transformation and growth ability of human embryo cells in vitro
    • 10.1080/09553009214552661, 1362764
    • Watanabe M, Suzuki M, Suzuki K, Nakano K, Watanabe K. Effect of multiple irradiation with low doses of gamma-rays on morphological transformation and growth ability of human embryo cells in vitro. Int J Radiat Biol 1992, 62:711-718. 10.1080/09553009214552661, 1362764.
    • (1992) Int J Radiat Biol , vol.62 , pp. 711-718
    • Watanabe, M.1    Suzuki, M.2    Suzuki, K.3    Nakano, K.4    Watanabe, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.