-
1
-
-
0034326802
-
Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation
-
Ahn J.Y., Schwarz J.K., Piwnica-Worms H., and Canman C.E. 2000. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res. 60: 5934.
-
(2000)
Cancer Res.
, vol.60
, pp. 5934
-
-
Ahn, J.Y.1
Schwarz, J.K.2
Piwnica-Worms, H.3
Canman, C.E.4
-
2
-
-
0032508506
-
Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure
-
Akhmedov A.T., Frei C., Tsai-Pflugfelder M., Kemper B., Gasser S.M., and Jessberger R. 1998. Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure. J. Biol. Chem. 273: 24088.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24088
-
-
Akhmedov, A.T.1
Frei, C.2
Tsai-Pflugfelder, M.3
Kemper, B.4
Gasser, S.M.5
Jessberger, R.6
-
3
-
-
0037017393
-
Condensin and cohesin display different arm conformations with characteristic hinge angles
-
Anderson D.E., Losada A., Erickson H.P., and Hirano T. 2002. Condensin and cohesin display different arm conformations with characteristic hinge angles. J. Cell Biol. 156: 419.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 419
-
-
Anderson, D.E.1
Losada, A.2
Erickson, H.P.3
Hirano, T.4
-
4
-
-
0242490999
-
ATP hydrolysis is required for cohesin's association with chromosomes
-
Arumugam P., Gruber S., Tanaka K., Haering C.H., Mechtler K., and Nasmyth K. 2003. ATP hydrolysis is required for cohesin's association with chromosomes. Curr. Biol. 13: 1941.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1941
-
-
Arumugam, P.1
Gruber, S.2
Tanaka, K.3
Haering, C.H.4
Mechtler, K.5
Nasmyth, K.6
-
5
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist C.J. and Kastan M.B. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499.
-
(2003)
Nature
, vol.421
, pp. 499
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
6
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
Banin S., Moyal L., Shieh S., Taya Y., Anderson C.W., Chessa L., Smorodinsky N.I., Prives C., Reiss Y., Shiloh Y., and Ziv Y. 1998. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281: 1674.
-
(1998)
Science
, vol.281
, pp. 1674
-
-
Banin, S.1
Moyal, L.2
Shieh, S.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
Ziv, Y.11
-
7
-
-
0035927713
-
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses
-
Bao S., Tibbetts R.S., Brumbaugh K.M., Fang Y., Richardson D.A., Ali A., Chen S.M., Abraham R.T., and Wang X.F. 2001. ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature 411: 969.
-
(2001)
Nature
, vol.411
, pp. 969
-
-
Bao, S.1
Tibbetts, R.S.2
Brumbaugh, K.M.3
Fang, Y.4
Richardson, D.A.5
Ali, A.6
Chen, S.M.7
Abraham, R.T.8
Wang, X.F.9
-
8
-
-
0027059030
-
Cloning and characterization of rad21 an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair
-
Birkenbihl R.P. and Subramani S. 1992. Cloning and characterization of rad21 an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair. Nucleic Acids Res. 20: 6605.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 6605
-
-
Birkenbihl, R.P.1
Subramani, S.2
-
10
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman C.E., Lim D.S., Cimprich K.A., Taya Y., Tamai K., Sakaguchi K., Appella E., Kastan M.B., and Siliciano J.D. 1998. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281: 1677.
-
(1998)
Science
, vol.281
, pp. 1677
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siliciano, J.D.9
-
11
-
-
0345732687
-
The Mre11 complex is required for ATM activation and the G2/M checkpoint
-
Carson C.T., Schwartz R.A., Stracker T.H., Lilley C.E., Lee D.V., and Weitzman M.D. 2003. The Mre11 complex is required for ATM activation and the G2/M checkpoint. EMBO J. 22: 6610.
-
(2003)
EMBO J.
, vol.22
, pp. 6610
-
-
Carson, C.T.1
Schwartz, R.A.2
Stracker, T.H.3
Lilley, C.E.4
Lee, D.V.5
Weitzman, M.D.6
-
12
-
-
0029999538
-
Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae
-
Castano I.B., Brzoska P.M., Sadoff B.U., Chen H., and Christman M.F. 1996. Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae. Genes Dev. 10: 2564.
-
(1996)
Genes Dev.
, vol.10
, pp. 2564
-
-
Castano, I.B.1
Brzoska, P.M.2
Sadoff, B.U.3
Chen, H.4
Christman, M.F.5
-
13
-
-
3543079922
-
Chromatin association of rad17 is required for an ataxia telangiectasia and rad-related kinase-mediated S-phase checkpoint in response to low-dose ultraviolet radiation
-
Garg R., Callens S., Lim D.S., Canman C.E., Kastan M.B., and Xu B. 2004. Chromatin association of rad17 is required for an ataxia telangiectasia and rad-related kinase-mediated S-phase checkpoint in response to low-dose ultraviolet radiation. Mol. Cancer Res. 2: 362.
-
(2004)
Mol. Cancer Res.
, vol.2
, pp. 362
-
-
Garg, R.1
Callens, S.2
Lim, D.S.3
Canman, C.E.4
Kastan, M.B.5
Xu, B.6
-
14
-
-
0037459376
-
Chromosomal cohesin forms a ring
-
Gruber S., Haering C.H., and Nasmyth K. 2003. Chromosomal cohesin forms a ring. Cell 112: 765.
-
(2003)
Cell
, vol.112
, pp. 765
-
-
Gruber, S.1
Haering, C.H.2
Nasmyth, K.3
-
15
-
-
0345060775
-
Building and breaking bridges between sister chromatids
-
Haering C.H. and Nasmyth K. 2003. Building and breaking bridges between sister chromatids. Bioessays 25: 1178.
-
(2003)
Bioessays
, vol.25
, pp. 1178
-
-
Haering, C.H.1
Nasmyth, K.2
-
16
-
-
0036242551
-
Molecular architecture of SMC proteins and the yeast cohesin complex
-
Haering C.H., Lowe J., Hochwagen A., and Nasmyth K. 2002. Molecular architecture of SMC proteins and the yeast cohesin complex. Mol. Cell 9: 773.
-
(2002)
Mol. Cell
, vol.9
, pp. 773
-
-
Haering, C.H.1
Lowe, J.2
Hochwagen, A.3
Nasmyth, K.4
-
17
-
-
0036834549
-
Hinge-mediated dimerization of SMC protein is essential for its dynamic interaction with DNA
-
Hirano M. and Hirano T. 2002. Hinge-mediated dimerization of SMC protein is essential for its dynamic interaction with DNA. EMBO J. 21: 5733.
-
(2002)
EMBO J.
, vol.21
, pp. 5733
-
-
Hirano, M.1
Hirano, T.2
-
18
-
-
0029782098
-
SMC proteins constitute two subunits of the mammalian recombination complex RC-1
-
Jessberger R., Riwar B., Baechtold H., and Akhmedov A.T. 1996. SMC proteins constitute two subunits of the mammalian recombination complex RC-1. EMBO J. 15: 4061.
-
(1996)
EMBO J.
, vol.15
, pp. 4061
-
-
Jessberger, R.1
Riwar, B.2
Baechtold, H.3
Akhmedov, A.T.4
-
20
-
-
0036500555
-
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
-
Kim S.T., Xu B., and Kastan M.B. 2002. Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev. 16: 560.
-
(2002)
Genes Dev.
, vol.16
, pp. 560
-
-
Kim, S.T.1
Xu, B.2
Kastan, M.B.3
-
21
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
Kim S.T., Lim D.S., Canman C.E., and Kastan M.B. 1999. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274: 37538.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37538
-
-
Kim, S.T.1
Lim, D.S.2
Canman, C.E.3
Kastan, M.B.4
-
22
-
-
2942687831
-
Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway
-
Kitagawa R., Bakkenist C.J., McKinnon P.J., and Kastan M.B. 2004. Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes Dev. 18: 1423.
-
(2004)
Genes Dev.
, vol.18
, pp. 1423
-
-
Kitagawa, R.1
Bakkenist, C.J.2
McKinnon, P.J.3
Kastan, M.B.4
-
23
-
-
1842431822
-
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
-
Lee J.H. and Paull T.T. 2004. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science 304: 93.
-
(2004)
Science
, vol.304
, pp. 93
-
-
Lee, J.H.1
Paull, T.T.2
-
24
-
-
17644409069
-
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
-
_. 2005. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science 308: 551.
-
(2005)
Science
, vol.308
, pp. 551
-
-
-
25
-
-
0034611728
-
ATM phosphorylates p95/nbs1 in an Sphase checkpoint pathway
-
Lim D.S., Kim S.T., Xu B., Maser R.S., Lin J., Petrini J.H., and Kastan M.B. 2000. ATM phosphorylates p95/nbs1 in an Sphase checkpoint pathway. Nature 404: 613.
-
(2000)
Nature
, vol.404
, pp. 613
-
-
Lim, D.S.1
Kim, S.T.2
Xu, B.3
Maser, R.S.4
Lin, J.5
Petrini, J.H.6
Kastan, M.B.7
-
26
-
-
0034641724
-
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
-
Matsuoka S., Rotman G., Ogawa A., Shiloh Y., Tamai K., and Elledge S.J. 2000. Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc. Natl. Acad. Sci. 97: 10389.
-
(2000)
Proc. Natl. Acad. Sci.
, vol.97
, pp. 10389
-
-
Matsuoka, S.1
Rotman, G.2
Ogawa, A.3
Shiloh, Y.4
Tamai, K.5
Elledge, S.J.6
-
27
-
-
0035339357
-
ATM-dependent phosphorylation of Mdm2 on serine 395: Role in p53 activation by DNA damage
-
Maya R., Balass M., Kim S.T., Shkedy D., Leal J.F., Shifman O., Moas M., Buschmann T., Ronai Z., Shiloh Y., Kastan M.B., Katzir E., and Oren M. 2001. ATM-dependent phosphorylation of Mdm2 on serine 395: Role in p53 activation by DNA damage. Genes Dev. 15: 1067.
-
(2001)
Genes Dev.
, vol.15
, pp. 1067
-
-
Maya, R.1
Balass, M.2
Kim, S.T.3
Shkedy, D.4
Leal, J.F.5
Shifman, O.6
Moas, M.7
Buschmann, T.8
Ronai, Z.9
Shiloh, Y.10
Kastan, M.B.11
Katzir, E.12
Oren, M.13
-
28
-
-
0030885925
-
Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
-
Michaelis C., Ciosk R., and Nasmyth K. 1997. Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids. Cell 91: 35.
-
(1997)
Cell
, vol.91
, pp. 35
-
-
Michaelis, C.1
Ciosk, R.2
Nasmyth, K.3
-
29
-
-
0346059615
-
53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage
-
Mochan T.A., Venere M., DiTullio R.A., Jr., and Halazonetis T.D. 2003. 53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage. Cancer Res. 63: 8586.
-
(2003)
Cancer Res.
, vol.63
, pp. 8586
-
-
Mochan, T.A.1
Venere, M.2
DiTullio Jr., R.A.3
Halazonetis, T.D.4
-
30
-
-
0037205292
-
Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA
-
Saitoh S., Chabes A., McDonald W.H., Thelander L., Yates J.R., and Russell P. 2002. Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA. Cell 109: 563.
-
(2002)
Cell
, vol.109
, pp. 563
-
-
Saitoh, S.1
Chabes, A.2
McDonald, W.H.3
Thelander, L.4
Yates, J.R.5
Russell, P.6
-
31
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky K., Bar-Shira A., Gilad S., Rotman G., Ziv Y., Vanagaite L., Tagle D.A., Smith S., Uziel T., and Sfez S., et al. 1995. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268: 1749.
-
(1995)
Science
, vol.268
, pp. 1749
-
-
Savitsky, K.1
Bar-Shira, A.2
Gilad, S.3
Rotman, G.4
Ziv, Y.5
Vanagaite, L.6
Tagle, D.A.7
Smith, S.8
Uziel, T.9
Sfez, S.10
-
32
-
-
4444292641
-
SMC1 coordinates DNA double-strand break repair pathways
-
Schar P., Fasi M., and Jessberger R. 2004. SMC1 coordinates DNA double-strand break repair pathways. Nucleic Acids Res. 32: 3921.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 3921
-
-
Schar, P.1
Fasi, M.2
Jessberger, R.3
-
33
-
-
0034798285
-
ATM: Genome stability, neuronal development, and cancer cross paths
-
Shiloh Y. and Kastan M.B. 2001. ATM: Genome stability, neuronal development, and cancer cross paths. Adv. Cancer Res. 83: 209.
-
(2001)
Adv. Cancer Res.
, vol.83
, pp. 209
-
-
Shiloh, Y.1
Kastan, M.B.2
-
34
-
-
0035954251
-
Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae
-
Sjogren C. and Nasmyth K. 2001. Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae. Curr. Biol. 11: 991.
-
(2001)
Curr. Biol.
, vol.11
, pp. 991
-
-
Sjogren, C.1
Nasmyth, K.2
-
35
-
-
0027893001
-
Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage
-
Slichenmyer W.J., Nelson W.G., Slebos R.J., and Kastan M.B. 1993. Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Res. 53: 4164.
-
(1993)
Cancer Res.
, vol.53
, pp. 4164
-
-
Slichenmyer, W.J.1
Nelson, W.G.2
Slebos, R.J.3
Kastan, M.B.4
-
36
-
-
10944232673
-
Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair
-
Strom L., Lindroos H.B., Shirahige K., and Sjogren C. 2004. Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair. Mol. Cell 16: 1003.
-
(2004)
Mol. Cell
, vol.16
, pp. 1003
-
-
Strom, L.1
Lindroos, H.B.2
Shirahige, K.3
Sjogren, C.4
-
37
-
-
0033167929
-
Structural maintenance of chromosomes (SMC) proteins: Conserved molecular properties for multiple biological functions
-
Strunnikov A.V. and Jessberger R. 1999. Structural maintenance of chromosomes (SMC) proteins: Conserved molecular properties for multiple biological functions. Eur. J. Biochem. 263: 6.
-
(1999)
Eur. J. Biochem.
, vol.263
, pp. 6
-
-
Strunnikov, A.V.1
Jessberger, R.2
-
38
-
-
0033522135
-
Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1
-
Stursberg S., Riwar B., and Jessberger R. 1999. Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1. Gene 228: 1.
-
(1999)
Gene
, vol.228
, pp. 1
-
-
Stursberg, S.1
Riwar, B.2
Jessberger, R.3
-
39
-
-
0037123768
-
Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways
-
Taniguchi T., Garcia-Higuera I., Xu B., Andreassen P.R., Gregory R.C., Kim S.T., Lane W.S., Kastan M.B., and D'Andrea A.D. 2002. Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. Cell 109: 459.
-
(2002)
Cell
, vol.109
, pp. 459
-
-
Taniguchi, T.1
Garcia-Higuera, I.2
Xu, B.3
Andreassen, P.R.4
Gregory, R.C.5
Kim, S.T.6
Lane, W.S.7
Kastan, M.B.8
D'Andrea, A.D.9
-
40
-
-
10944262393
-
DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain
-
Unal E., Arbel-Eden A., Sattler U., Shroff R., Lichten M., Haber J.E., and Koshland D. 2004. DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol. Cell 16: 991.
-
(2004)
Mol. Cell
, vol.16
, pp. 991
-
-
Unal, E.1
Arbel-Eden, A.2
Sattler, U.3
Shroff, R.4
Lichten, M.5
Haber, J.E.6
Koshland, D.7
-
41
-
-
1642499359
-
Quaternary structure of ATR and effects of ATRIP and replication protein a on its DNA binding and kinase activities
-
Unsal-Kacmaz K. and Sancar A. 2004. Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities. Mol. Cell. Biol. 24: 1292.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 1292
-
-
Unsal-Kacmaz, K.1
Sancar, A.2
-
42
-
-
0142136826
-
Requirement of the MRN complex for ATM activation by DNA damage
-
Uziel T., Lerenthal Y., Moyal L., Andegeko Y., Mittelman L., and Shiloh Y. 2003. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 22: 5612.
-
(2003)
EMBO J.
, vol.22
, pp. 5612
-
-
Uziel, T.1
Lerenthal, Y.2
Moyal, L.3
Andegeko, Y.4
Mittelman, L.5
Shiloh, Y.6
-
43
-
-
0034604445
-
Pol kappa: A DNA polymerase required for sister chromatid cohesion
-
Wang Z., Castano I.B., De Las Penas A., Adams C., and Christman M.F. 2000. Pol kappa: A DNA polymerase required for sister chromatid cohesion. Science 289: 774.
-
(2000)
Science
, vol.289
, pp. 774
-
-
Wang, Z.1
Castano, I.B.2
De Las Penas, A.3
Adams, C.4
Christman, M.F.5
-
44
-
-
0242540364
-
A model for ATP hydrolysis-dependent binding of cohesin to DNA
-
Weitzer S., Lehane C., and Uhlmann F. 2003. A model for ATP hydrolysis-dependent binding of cohesin to DNA. Curr. Biol. 13: 1930.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1930
-
-
Weitzer, S.1
Lehane, C.2
Uhlmann, F.3
-
45
-
-
0036146085
-
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
-
Xu B., Kim S.T., Lim D.S., and Kastan M.B. 2002a. Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Mol. Cell. Biol. 22: 1049.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1049
-
-
Xu, B.1
Kim, S.T.2
Lim, D.S.3
Kastan, M.B.4
-
46
-
-
0037102275
-
Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation
-
Xu B., O'Donnell A.H., Kim S.T., and Kastan M.B. 2002b. Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation. Cancer Res. 62: 4588.
-
(2002)
Cancer Res.
, vol.62
, pp. 4588
-
-
Xu, B.1
O'Donnell, A.H.2
Kim, S.T.3
Kastan, M.B.4
-
47
-
-
0036500690
-
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
-
Yazdi P.T., Wang Y., Zhao S., Patel N., Lee E.Y., and Qin J. 2002. SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes Dev. 16: 571.
-
(2002)
Genes Dev.
, vol.16
, pp. 571
-
-
Yazdi, P.T.1
Wang, Y.2
Zhao, S.3
Patel, N.4
Lee, E.Y.5
Qin, J.6
-
48
-
-
0034015540
-
Retinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1p
-
Zheng L., Chen Y., Riley D.J., Chen P.L., and Lee W.H. 2000. Retinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1p. Mol. Cell. Biol. 20: 3529.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3529
-
-
Zheng, L.1
Chen, Y.2
Riley, D.J.3
Chen, P.L.4
Lee, W.H.5
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