메뉴 건너뛰기




Volumn 29, Issue 1, 2010, Pages

Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; CASPASE 3; CASPASE 9; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE H3; PACLITAXEL; PROTEIN BCL 2; PROTEIN P27; SURVIVIN; VALPROIC ACID; ANTINEOPLASTIC AGENT; HDAC1 PROTEIN, HUMAN; HDAC2 PROTEIN, HUMAN; HISTONE; TUBULIN;

EID: 78249234725     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-29-149     Document Type: Article
Times cited : (47)

References (61)
  • 1
    • 27944437003 scopus 로고    scopus 로고
    • Concepts in the prevention of adenocarcinoma of the distal esophagus and proximal stomach
    • Concepts in the prevention of adenocarcinoma of the distal esophagus and proximal stomach. RF Souza SJ Spechler, CA cancer J Clin 2005 55 334 51
    • (2005) CA Cancer J Clin , vol.55 , pp. 334-51
    • Souza, R.F.1    Spechler, S.J.2
  • 2
    • 63149131482 scopus 로고    scopus 로고
    • Recent results of therapy for scirrhous gastric cancer
    • Recent results of therapy for scirrhous gastric cancer. M Ikeguchi T Miyake T Matsunaga,, et al. Surg Today 2009 39 290 4
    • (2009) Surg Today , vol.39 , pp. 290-4
    • Ikeguchi, M.1    Miyake, T.2    Matsunaga, T.3
  • 3
    • 0036016810 scopus 로고    scopus 로고
    • Peritoneal carcinomatosis and lymph node metastasis are prognostic indicators in patients with Borrmann type IV gastric carcinoma
    • Peritoneal carcinomatosis and lymph node metastasis are prognostic indicators in patients with Borrmann type IV gastric carcinoma. CY Chen CW Wu SS Lo MC Hsieh WY Lui KH Shen, Hepatogastroenterology 2002 49 874 7
    • (2002) Hepatogastroenterology , vol.49 , pp. 874-7
    • Chen, C.Y.1    Wu, C.W.2    Lo, S.S.3    Hsieh, M.C.4    Lui, W.Y.5    Shen, K.H.6
  • 4
    • 77949318561 scopus 로고    scopus 로고
    • Phase II study of weekly intravenous and intraperitoneal paclitaxel combined with S-1 for advanced gastric cancer with peritoneal metastasis
    • Phase II study of weekly intravenous and intraperitoneal paclitaxel combined with S-1 for advanced gastric cancer with peritoneal metastasis. H Ishigami J Kitayama S Kaisaki,, et al. Ann Oncol 2010 21 67 70
    • (2010) Ann Oncol , vol.21 , pp. 67-70
    • Ishigami, H.1    Kitayama, J.2    Kaisaki, S.3
  • 5
    • 47549110793 scopus 로고    scopus 로고
    • Dual anti-cancer effects of weekly intraperitoneal docetaxel in treatment of advanced gastric cancer patients with peritoneal carcinomatosis: A feasibility and pharmacokinetic study
    • Dual anti-cancer effects of weekly intraperitoneal docetaxel in treatment of advanced gastric cancer patients with peritoneal carcinomatosis: a feasibility and pharmacokinetic study. S Fushida J Kinoshita Y Yagi,, et al. Oncol Rep 2008 19 1305 10
    • (2008) Oncol Rep , vol.19 , pp. 1305-10
    • Fushida, S.1    Kinoshita, J.2    Yagi, Y.3
  • 6
    • 33846629672 scopus 로고    scopus 로고
    • Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma
    • Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma. MA Shah RK Ramanathan DH Ilson,, et al. J Clin Oncol 2006 24 5201 6
    • (2006) J Clin Oncol , vol.24 , pp. 5201-6
    • Shah, M.A.1    Ramanathan, R.K.2    Ilson, D.H.3
  • 7
    • 33847663871 scopus 로고    scopus 로고
    • Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study)
    • Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study). C Pinto F Di Fabio S Siena,, et al. Ann Oncol 2007 18 510 7
    • (2007) Ann Oncol , vol.18 , pp. 510-7
    • Pinto, C.1    Di Fabio, F.2    Siena, S.3
  • 8
    • 1242319394 scopus 로고    scopus 로고
    • Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis
    • Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis. B Schniewind M Christgen R Kurdow,, et al. Int J Cancer 2004 109 182 8
    • (2004) Int J Cancer , vol.109 , pp. 182-8
    • Schniewind, B.1    Christgen, M.2    Kurdow, R.3
  • 9
    • 0036280745 scopus 로고    scopus 로고
    • Effects of histone acetylation and DNA methylation on p21 (WAF1) regulation
    • Effects of histone acetylation and DNA methylation on p21 (WAF1) regulation. JY Fang YY Lu, World J Gastroenterol 2002 8 400 5
    • (2002) World J Gastroenterol , vol.8 , pp. 400-5
    • Fang, J.Y.1    Lu, Y.Y.2
  • 10
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Translating the histone code. T Jenuwein CD Alli's, Science 2001 293 1074 80
    • (2001) Science , vol.293 , pp. 1074-80
    • Jenuwein, T.1    Alli'S, C.D.2
  • 12
    • 0036008097 scopus 로고    scopus 로고
    • Deacetylase enzymes: Biological functions and the use of small-molecule inhibitors
    • Deacetylase enzymes: biological functions and the use of small-molecule inhibitors. CM Grozinger SL Schreiber, Chem Biol 2002 9 3 16
    • (2002) Chem Biol , vol.9 , pp. 3-16
    • Grozinger, C.M.1    Schreiber, S.L.2
  • 13
    • 0035862199 scopus 로고    scopus 로고
    • The human histone deacetylase family
    • The human histone deacetylase family. SG Gray TJ Ekström, Exp Cell Res 2001 262 75 83
    • (2001) Exp Cell Res , vol.262 , pp. 75-83
    • Gray, S.G.1    Ekström, T.J.2
  • 14
    • 11844278521 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors
    • Histone deacetylase inhibitors. C Monneret, Eur J Med Chem 2005 40 1 13
    • (2005) Eur J Med Chem , vol.40 , pp. 1-13
    • Monneret, C.1
  • 15
    • 33745920222 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors:gathering pace
    • Histone deacetylase inhibitors:gathering pace. N Carey NB La Thangue, Curr Opin Pharmacol 2006 6 369 75
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 369-75
    • Carey, N.1    La Thangue, N.B.2
  • 16
    • 0034672294 scopus 로고    scopus 로고
    • Effect of Trichostatin A on cell growth and expression of cell cycle-and apoptosis-related molecules in human gastric and oral carcinoma cell lines
    • Effect of Trichostatin A on cell growth and expression of cell cycle-and apoptosis-related molecules in human gastric and oral carcinoma cell lines. T Suzuki H Yokozaki H Kuniyasu,, et al. Int J Cancer 2000 88 992 7
    • (2000) Int J Cancer , vol.88 , pp. 992-7
    • Suzuki, T.1    Yokozaki, H.2    Kuniyasu, H.3
  • 17
    • 33749187262 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines
    • Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines. X Zhang M Yashiro J Ren,, et al. Oncol Rep 2006 16 563 8
    • (2006) Oncol Rep , vol.16 , pp. 563-8
    • Zhang, X.1    Yashiro, M.2    Ren, J.3
  • 18
    • 55949119320 scopus 로고    scopus 로고
    • Valproic acid inhibits the growth of cervical cancer both in vitro and in vivo
    • Valproic acid inhibits the growth of cervical cancer both in vitro and in vivo. S Sami N Höti HM Xu Z Shen X Huang, J Biochem 2008 144 357 62
    • (2008) J Biochem , vol.144 , pp. 357-62
    • Sami, S.1    Höti, N.2    Xu, H.M.3    Shen, Z.4    Huang, X.5
  • 19
    • 0037925520 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2
    • The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2. OH Kramer P Zhu HP Ostendorff,, et al. EMBO J 2003 22 3411 20
    • (2003) EMBO J , vol.22 , pp. 3411-20
    • Kramer, O.H.1    Zhu, P.2    Ostendorff, H.P.3
  • 20
    • 18244383806 scopus 로고    scopus 로고
    • Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
    • Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. M Göttlicher S Minucci P Zhu,, et al. EMBO J 2001 20 6969 78
    • (2001) EMBO J , vol.20 , pp. 6969-78
    • Göttlicher, M.1    Minucci, S.2    Zhu, P.3
  • 21
    • 33749572938 scopus 로고    scopus 로고
    • Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells
    • Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells. A Hrzenjak F Moinfar ML Kremser,, et al. Mol Cancer Ther 2006 5 2203 10
    • (2006) Mol Cancer Ther , vol.5 , pp. 2203-10
    • Hrzenjak, A.1    Moinfar, F.2    Kremser, M.L.3
  • 22
    • 24044478600 scopus 로고    scopus 로고
    • P21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells
    • p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells. P Rocchi R Tonelli C Camerin,, et al. Oncol Rep 2005 13 1139 44
    • (2005) Oncol Rep , vol.13 , pp. 1139-44
    • Rocchi, P.1    Tonelli, R.2    Camerin, C.3
  • 23
    • 35548967147 scopus 로고    scopus 로고
    • Human endometrial and ovarian cancer cells: Histone deacetylase inhibitors exhibit antiproliferative activity, potently induce cell cycle arrest, and stimulate apoptosis
    • Human endometrial and ovarian cancer cells: histone deacetylase inhibitors exhibit antiproliferative activity, potently induce cell cycle arrest, and stimulate apoptosis. N Takai H Narahara, Curr Med Chem 2007 14 2548 53
    • (2007) Curr Med Chem , vol.14 , pp. 2548-53
    • Takai, N.1    Narahara, H.2
  • 24
    • 0037012344 scopus 로고    scopus 로고
    • Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228
    • Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228. X Yu ZS Guo MG Marcu,, et al. J Natl Cancer Inst 2002 94 504 13
    • (2002) J Natl Cancer Inst , vol.94 , pp. 504-13
    • Yu, X.1    Guo, Z.S.2    Marcu, M.G.3
  • 25
    • 0036731055 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity
    • Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity. MV Blagosklonny R Robey DL Sackett,, et al. Mol Cancer Ther 2002 1 37 41
    • (2002) Mol Cancer Ther , vol.1 , pp. 37-41
    • Blagosklonny, M.V.1    Robey, R.2    Sackett, D.L.3
  • 26
    • 35948965312 scopus 로고    scopus 로고
    • Valproic acid enhances tubulin acetylation and apoptotic activity of paclitaxel on anaplastic thyroid cancer cell lines
    • Valproic acid enhances tubulin acetylation and apoptotic activity of paclitaxel on anaplastic thyroid cancer cell lines. MG Catalano R Poli M Pugliese N Fortunati G Boccuzzi, Endocr Relat Cancer 2007 14 839 45
    • (2007) Endocr Relat Cancer , vol.14 , pp. 839-45
    • Catalano, M.G.1    Poli, R.2    Pugliese, M.3    Fortunati, N.4    Boccuzzi, G.5
  • 27
    • 0027942353 scopus 로고    scopus 로고
    • The taxoids: Paclitaxel and docetaxel
    • The taxoids: paclitaxel and docetaxel. K Gelmon, Lancet 344 1267 72
    • Lancet , vol.344 , pp. 1267-72
    • Gelmon, K.1
  • 28
    • 0035865144 scopus 로고    scopus 로고
    • Phase III trial of standard-dose intravenous cisplatin plus paclitaxel versus moderately high-dose carboplatin followed by intravenous paclitaxel and intraperitoneal cisplatin in small-volume stage III ovarian carcinoma: An intergroup study of the Gynecologic Oncology Group, Southwestern Oncology Group, and Eastern Cooperative Oncology Group
    • Phase III trial of standard-dose intravenous cisplatin plus paclitaxel versus moderately high-dose carboplatin followed by intravenous paclitaxel and intraperitoneal cisplatin in small-volume stage III ovarian carcinoma: an intergroup study of the Gynecologic Oncology Group, Southwestern Oncology Group, and Eastern Cooperative Oncology Group. M Markman BN Bundy DS Alberts,, et al. J Clin Oncol 2001 19 1001 7
    • (2001) J Clin Oncol , vol.19 , pp. 1001-7
    • Markman, M.1    Bundy, B.N.2    Alberts, D.S.3
  • 29
    • 0842325787 scopus 로고    scopus 로고
    • Histone deacetylase is a target of valproic acid-mediated cellular differentiation
    • Histone deacetylase is a target of valproic acid-mediated cellular differentiation. N Gurvich OM Tsygankova JL Meinkoth PS Klein, Cancer Res 2004 64 1079 86
    • (2004) Cancer Res , vol.64 , pp. 1079-86
    • Gurvich, N.1    Tsygankova, O.M.2    Meinkoth, J.L.3    Klein, P.S.4
  • 31
    • 17744375806 scopus 로고    scopus 로고
    • Role of p53 status in chemosensitivity determination of cancer cells against histone deacetylase inhibitor sodium butyrate
    • Role of p53 status in chemosensitivity determination of cancer cells against histone deacetylase inhibitor sodium butyrate. J Joseph N Wajapeyee K Somasundaram, Int J Cancer 2005 115 11 8
    • (2005) Int J Cancer , vol.115 , pp. 11-8
    • Joseph, J.1    Wajapeyee, N.2    Somasundaram, K.3
  • 32
    • 0037974533 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor FR901228 (desipeptide) restores expression and function of pseudo-null p53
    • The histone deacetylase inhibitor FR901228 (desipeptide) restores expression and function of pseudo-null p53. M Kitazono S Bates P Fok T Fojo MV Blagosklonny, Cancer Biol Ther 2002 1 665 8
    • (2002) Cancer Biol Ther , vol.1 , pp. 665-8
    • Kitazono, M.1    Bates, S.2    Fok, P.3    Fojo, T.4    Blagosklonny, M.V.5
  • 33
    • 0029968617 scopus 로고    scopus 로고
    • Fibrosis in the peritoneum induced by scirrhous gastric cancer cells may act as 'soil' for peritoneal dissemination
    • Fibrosis in the peritoneum induced by scirrhous gastric cancer cells may act as 'soil' for peritoneal dissemination. M Yashiro YS Chung S Nishimura T Inoue M Sowa, Cancer 1996 77 1668 75
    • (1996) Cancer , vol.77 , pp. 1668-75
    • Yashiro, M.1    Chung, Y.S.2    Nishimura, S.3    Inoue, T.4    Sowa, M.5
  • 34
    • 77649274997 scopus 로고    scopus 로고
    • Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells
    • Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells. O Shinto M Yashiro H Kawajiri,, et al. Br J Cancer 2010 102 844 51
    • (2010) Br J Cancer , vol.102 , pp. 844-51
    • Shinto, O.1    Yashiro, M.2    Kawajiri, H.3
  • 35
    • 0031724451 scopus 로고    scopus 로고
    • Over expression of transforming growth factor-beta1 in scirrhous carcinoma of the stomach correlates with decreased survival
    • Over expression of transforming growth factor-beta1 in scirrhous carcinoma of the stomach correlates with decreased survival. S Kinugasa S Abe M Tachibana,, et al. Oncology 1998 55 582 7
    • (1998) Oncology , vol.55 , pp. 582-7
    • Kinugasa, S.1    Abe, S.2    Tachibana, M.3
  • 36
    • 0030996215 scopus 로고    scopus 로고
    • Transforming growth factor-beta and hepatocyte growth factor produced by gastric fibroblasts stimulate the invasiveness of scirrhous gastric cancer cells
    • Transforming growth factor-beta and hepatocyte growth factor produced by gastric fibroblasts stimulate the invasiveness of scirrhous gastric cancer cells. T Inoue YS Chung M Yashiro,, et al. Jpn J Cancer Res 1997 88 152 9
    • (1997) Jpn J Cancer Res , vol.88 , pp. 152-9
    • Inoue, T.1    Chung, Y.S.2    Yashiro, M.3
  • 37
    • 0034132753 scopus 로고    scopus 로고
    • TGF-beta1 secreted by gastric fibroblasts up-regulates CD44 H expression and stimulates the peritoneal metastatic ability of scirrhous gastric cancer cells
    • TGF-beta1 secreted by gastric fibroblasts up-regulates CD44 H expression and stimulates the peritoneal metastatic ability of scirrhous gastric cancer cells. T Koyama M Yashiro T Inoue,, et al. Int J Oncol 2000 16 355 62
    • (2000) Int J Oncol , vol.16 , pp. 355-62
    • Koyama, T.1    Yashiro, M.2    Inoue, T.3
  • 38
    • 77954862083 scopus 로고    scopus 로고
    • The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells
    • The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells. MA Taylor JG Parvani WP Schiemann, J Mammary Gland Biol Neoplasia 2010 15 169 90
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 169-90
    • Taylor, M.A.1    Parvani, J.G.2    Schiemann, W.P.3
  • 39
    • 74949093198 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer
    • Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer. K Miyazono, Proc Jpn Acad Ser B Phys Biol Sci 2009 85 314 23
    • (2009) Proc Jpn Acad ser B Phys Biol Sci , vol.85 , pp. 314-23
    • Miyazono, K.1
  • 40
    • 70449727057 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer progression
    • Epithelial-mesenchymal transition in cancer progression. M Gos J Mioszewska M Przybyszewska, Postepy Biochem 2009 55 121 8
    • (2009) Postepy Biochem , vol.55 , pp. 121-8
    • Gos, M.1    Mioszewska, J.2    Przybyszewska, M.3
  • 41
    • 34848863333 scopus 로고    scopus 로고
    • Histone deacetylase 4 is required for TGFbeta1-induced myofibroblastic differentiation
    • Histone deacetylase 4 is required for TGFbeta1-induced myofibroblastic differentiation. W Glenisson V Castronovo D Waltregny, Biochim Biophys Acta 2007 1773 1572 82
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1572-82
    • Glenisson, W.1    Castronovo, V.2    Waltregny, D.3
  • 42
    • 37849019672 scopus 로고    scopus 로고
    • Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
    • Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors. N Khan M Jeffers S Kumar,, et al. Biochem J 2008 409 581 9
    • (2008) Biochem J , vol.409 , pp. 581-9
    • Khan, N.1    Jeffers, M.2    Kumar, S.3
  • 43
    • 0037416151 scopus 로고    scopus 로고
    • HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo
    • HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo. Y Zhang N Li C Caron,, et al. EMBO J 2003 22 1168 79
    • (2003) EMBO J , vol.22 , pp. 1168-79
    • Zhang, Y.1    Li, N.2    Caron, C.3
  • 44
    • 0036731055 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity
    • Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity. MV Blagosklonny R Robey DL Sackett,, et al. Mol Cancer Ther 2002 1 937 41
    • (2002) Mol Cancer Ther , vol.1 , pp. 937-41
    • Blagosklonny, M.V.1    Robey, R.2    Sackett, D.L.3
  • 45
    • 0037161744 scopus 로고    scopus 로고
    • HDAC6 is a microtubule-associated deacetylase
    • HDAC6 is a microtubule-associated deacetylase. C Hubbert A Guardiola R Shao,, et al. Nature 2002 417 455 8
    • (2002) Nature , vol.417 , pp. 455-8
    • Hubbert, C.1    Guardiola, A.2    Shao, R.3
  • 46
    • 33845209109 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells
    • Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells. SC Dowdy S Jiang XC Zhou,, et al. Mol Cancer Ther 2006 5 2767 76
    • (2006) Mol Cancer Ther , vol.5 , pp. 2767-76
    • Dowdy, S.C.1    Jiang, S.2    Zhou, X.C.3
  • 47
    • 77649134470 scopus 로고    scopus 로고
    • Low-dose paclitaxel ameliorates renal fibrosis in rat UUO model by inhibition of TGF-beta/Smad activity
    • Low-dose paclitaxel ameliorates renal fibrosis in rat UUO model by inhibition of TGF-beta/Smad activity. D Zhang L Sun W Xian,, et al. Lab Invest 2010 90 436 47
    • (2010) Lab Invest , vol.90 , pp. 436-47
    • Zhang, D.1    Sun, L.2    Xian, W.3
  • 48
    • 34447256779 scopus 로고    scopus 로고
    • Paclitaxel interrupts TGF-beta1 signaling between gallbladder epithelial cells and myofibroblasts
    • Paclitaxel interrupts TGF-beta1 signaling between gallbladder epithelial cells and myofibroblasts. HS Choi CE Savard JW Choi R Kuver SP Lee, J Surg Res 2007 141 183 91
    • (2007) J Surg Res , vol.141 , pp. 183-91
    • Choi, H.S.1    Savard, C.E.2    Choi, J.W.3    Kuver, R.4    Lee, S.P.5
  • 49
    • 29644432536 scopus 로고    scopus 로고
    • Paclitaxel modulates TGFbeta signaling in scleroderma skin grafts in immunodeficient mice
    • Paclitaxel modulates TGFbeta signaling in scleroderma skin grafts in immunodeficient mice. X Liu S Zhu T Wang,, et al. PLoS Med 2005 2 354
    • (2005) PLoS Med , vol.2 , pp. 5354
    • Liu, X.1    Zhu, S.2    Wang, T.3
  • 50
    • 72449139586 scopus 로고    scopus 로고
    • Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition
    • Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition. W Guo B Shan RC Klingsberg X Qin JA Lasky, Am J Physiol Lung Cell Mol Physiol 2009 297 864 70
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.297 , pp. 12864-70
    • Guo, W.1    Shan, B.2    Klingsberg, R.C.3    Qin, X.4    Lasky, J.A.5
  • 51
    • 34447304130 scopus 로고    scopus 로고
    • Valproic acid (VPA) in patients with refractory advanced cancer: A dose escalating phase i clinical trial
    • Valproic acid (VPA) in patients with refractory advanced cancer: a dose escalating phase I clinical trial. A Atmaca SE Al-Batran A Maurer,, et al. Br J Cancer 2007 97 177 82
    • (2007) Br J Cancer , vol.97 , pp. 177-82
    • Atmaca, A.1    Al-Batran, S.E.2    Maurer, A.3
  • 52
    • 58149263278 scopus 로고    scopus 로고
    • A phase I-II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma
    • A phase I-II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma. A Rocca S Minucci G Tosti,, et al. Br J Cancer 2009 100 28 36
    • (2009) Br J Cancer , vol.100 , pp. 28-36
    • Rocca, A.1    Minucci, S.2    Tosti, G.3
  • 53
    • 0035119485 scopus 로고    scopus 로고
    • A phase II study to establish the efficacy and toxicity of sodium valproate in patients with cancer-related neuropathic pain
    • A phase II study to establish the efficacy and toxicity of sodium valproate in patients with cancer-related neuropathic pain. JR Hardy EA Rees B Gwilliam J Ling K Broadley R A'Hern, J Pain Symptom Manage 2001 21 204 9
    • (2001) J Pain Symptom Manage , vol.21 , pp. 204-9
    • Hardy, J.R.1    Rees, E.A.2    Gwilliam, B.3    Ling, J.4    Broadley, K.5    A'Hern, R.6
  • 54
    • 45849101673 scopus 로고    scopus 로고
    • Targeting cancer and neuropathy with histone deacetylase inhibitors: Two birds with one stone?
    • Targeting cancer and neuropathy with histone deacetylase inhibitors: two birds with one stone? V Rodriguez-Menendez L Tremolizzo G Cavaletti, Curr Cancer Drug Targets 2008 8 266 74
    • (2008) Curr Cancer Drug Targets , vol.8 , pp. 266-74
    • Rodriguez-Menendez, V.1    Tremolizzo, L.2    Cavaletti, G.3
  • 55
    • 58149174109 scopus 로고    scopus 로고
    • Phase i study of epigenetic modulation with 5-azacytidine and valproic acid in patients with advanced cancers
    • Phase I study of epigenetic modulation with 5-azacytidine and valproic acid in patients with advanced cancers. F Braiteh AO Soriano G Garcia-Manero,, et al. Clin Cancer Res 2008 14 6296 301
    • (2008) Clin Cancer Res , vol.14 , pp. 6296-301
    • Braiteh, F.1    Soriano, A.O.2    Garcia-Manero, G.3
  • 56
    • 65249141665 scopus 로고    scopus 로고
    • Clinical and biological effects of valproic acid as a histone deacetylase inhibitor on tumor and surrogate tissues: Phase I/II trial of valproic acid and epirubicin/FEC
    • Clinical and biological effects of valproic acid as a histone deacetylase inhibitor on tumor and surrogate tissues: phase I/II trial of valproic acid and epirubicin/FEC. P Munster D Marchion E Bicaku,, et al. Clin Cancer Res 2009 15 2488 96
    • (2009) Clin Cancer Res , vol.15 , pp. 2488-96
    • Munster, P.1    Marchion, D.2    Bicaku, E.3
  • 57
    • 38449100788 scopus 로고    scopus 로고
    • Expression profile of class i histone deacetylases in human cancer tissues
    • Expression profile of class I histone deacetylases in human cancer tissues. M Nakagawa Y Oda T Eguchi,, et al. Oncol Rep 2007 18 769 74
    • (2007) Oncol Rep , vol.18 , pp. 769-74
    • Nakagawa, M.1    Oda, Y.2    Eguchi, T.3
  • 58
    • 38549157208 scopus 로고    scopus 로고
    • Association of patterns of class i histone deacetylase expression with patient prognosis in gastric cancer: A retrospective analysis
    • Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis. W Weichert A Röske V Gekeler,, et al. Lancet Oncol 2008 9 139 48
    • (2008) Lancet Oncol , vol.9 , pp. 139-48
    • Weichert, W.1    Röske, A.2    Gekeler, V.3
  • 59
    • 0035676731 scopus 로고    scopus 로고
    • Expression profile of histone deacetylase 1 in gastric cancer tissues
    • Expression profile of histone deacetylase 1 in gastric cancer tissues. JH Choi HJ Kwon BI Yoon,, et al. Jpn J Cancer Res 2001 92 1300 4
    • (2001) Jpn J Cancer Res , vol.92 , pp. 1300-4
    • Choi, J.H.1    Kwon, H.J.2    Yoon, B.I.3
  • 60
    • 21044447215 scopus 로고    scopus 로고
    • Increased expression of histone deacetylase 2 is found in human gastric cancer
    • Increased expression of histone deacetylase 2 is found in human gastric cancer. J Song JH Noh JH Lee,, et al. APMIS 2005 113 264 8
    • (2005) APMIS , vol.113 , pp. 264-8
    • Song, J.1    Noh, J.H.2    Lee, J.H.3
  • 61
    • 38549157208 scopus 로고    scopus 로고
    • Association of patterns of class i histone deacetylase expression with patient prognosis in gastric cancer: A retrospective analysis
    • Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis. W Weichert A Röske V Gekeler,, et al. Lancet Oncol 2008 9 139 48
    • (2008) Lancet Oncol , vol.9 , pp. 139-48
    • Weichert, W.1    Röske, A.2    Gekeler, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.