Transforming growth factor-β and hepatocyte growth factor produced by gastric fibroblasts stimulate the invasiveness of scirrhous gastric cancer cells

Japanese Journal of Cancer Research

Volumn 88, Issue 2, 1997, Pages 152-159

  Inoue, Tohru ^a   Chung, Yong Suk ^a   Yashiro, Masakazu ^a   Nishimura, Shigehiko ^a   Hasuma, Tadayoshi ^a   Otani, Shuzo ^a   Sowa, Michio ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Fibroblast; Hepatocyte growth factor; Invasion; Sirrhous gastric carcinoma; Transforming growth factor

Indexed keywords

CYTOKINE ANTIBODY; GROWTH FACTOR RECEPTOR; NEUTRALIZING ANTIBODY; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CASE REPORT; CELL INVASION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STOMACH CARCINOMA;

EID: 0030996215     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1997.tb00360.x     Document Type: Article

References (35)

1. Kiyasu, Y., Kaneshima, S. and Koga, S. Morphogenesis of peritoneal metastasis in human gastric cancer. Cancer Res., 41, 1236-1239 (1981).
2. Yashiro, M., Chung, Y. S., Nishimura, S., Inoue, T. and Sowa, M. Peritoneal metastatic model for human scir- rhous gastric carcinoma in nude mice. Clin. Exp. Metasta- sis. 14, 43-54 (1996).
3. Yashiro, M., Chung, Y. S., Nishimura, S., Inoue, T. and Sowa, M. Establishment of two new scirrhous gastric cancer cell lines: analysis of factors associated with dis- seminated metastasis. Br. J. Cancer, 72, 1200-1210 (1995).
4. Tahara, E. Growth factors and oncogenes in human gastrointestinal carcinomas. J. Cancer Res. Clin. Oncol., 116, 121-131 (1990).
5. Shimura, H., Date, K., Matsumoto, K., Nakamura, T. and Tanaka, M. Induction of invasive growth in a gallbladder cancer cell line by hepatocyte growth factor in vitro. Jpn. J. Cancer Res., 86, 662-669 (1995).
6. Gohji, K., Nakajima, M., Fabra, A., Bucana, C. D., von Eschenbach, A. C., Tsuruo, T. and Fidler, I. J. Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibloblasts. Jpn. J. Cancer Res., 85, 152- 160 (1994).
7. van den Hooff, A. Stromal involvement in malignant growth. Adv. Cancer Res., 50, 159-196 (1988).
8. Morikawa, K., Walker, S. M., Nakajima, M., Pathak, S., Jessup, J. M. and Fidler, I. J. Influence of the organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res., 48, 6863-6871 (1988).
9. Nakajima, M. and Chop, A. M. Tumor invasion and extracellular matrix degradative enzymes: regulation of activity by organ factors. Sem. Cancer Biol., 2, 115-127 (1991).
10. Fabra, A., Nakajima, M., Bucana, C. D. and Fidler, I. J. Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice. Differentiation, 52, 101-110 (1992).
11. Matsumoto, K., Date, K., Shimura, H. and Nakamura, T. Acquisition of invasive phenotype in gallbladder cancer cells via mutual interaction of stromal fibroblasts and cancer cells as mediated by hepatocyte growth factor. Jpn, J. Cancer Res., 87, 702-710 (1996).
12. Yashiro, M., Chung, Y.-S. and Sowa, M. Role of ortho- topic fibroblasts in the development of scirrhous gastric carcinoma. Jpn. J. Cancer Res., 85, 883-886 (1994).
13. Albini, A., Iwamoto, Y., Kleinman, H. K., Martin, G. R., Aaronson, S. A., Kozlowski, J. M. and McEvan, R. N. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res., 47, 3239-3245 (1987).
14. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-687 (1970).
15. Welch, D. R., Fabra, A. and Nakajima, M. Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential. Proc. Natl. Acad. Sci. USA, 87, 7678-7682 (1990).
16. Ueki, N., Ohkawa, T., Yokoyama, Y., Maeda, J., Kawai, Y., Ikeda, T., Amuro, Y., Hada, T. and Higashio, K. Potentiation of metastatic capacity by transforming growth factor-β1 gene transfection. Jpn. J. Cancer Res., 84, 589-593 (1993).
17. Mooradian, D. L., McCarthy, J. B., Komanduri, K. V. and Furcht, L. T. Effects of transforming growth factor- β1 on human pulmonary adenocarcinoma cell adhesion, motility, and invasion in vitro. J. Natl. Cancer Inst., 84, 523-527 (1992).
18. Merzak, A., McCrea, S., Koocheckpour, S. and Pilkington, G. J. Control of human glioma cell growth, migration and invasion In vitro by transforming growth factor β1. Br. J. Cancer, 70, 199-203 (1994).
19. Mahara, K., Kato, J., Terui, T., Takimoto, R., Horimoto, M., Murakami, T., Mogi, Y., Watanabe, N., Kohgo, Y. and Niitsu, Y. Transforming growth factor β1 secreted from scirrhous gastric cancer cells is associated with excess collagen deposition in the tissue. Br. J. Cancer, 69, 777-783 (1994).
20. Guirguits, R., Marguies, I., Taraboletti, G., Schiffmann, E. and Liotta, L. Cytokine-induced pseudopodal protrusion is coupled to tumor cell migration. Nature, 329, 261-263 (1987).
21. Liotta, L. A., Rao, C. N. and Barsky, S. H. Tumor invasion and the extracellular matrix. Lab. Invest., 49, 636-649 (1983).
22. Saksela, O., Moscatelli, D. and Rifkin, D. B. The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen ac- tivator activity in capillary endothelial cells. J. Cell Biol., 105, 957-963 (1987).
23. Weidner, K. M., Arakaki, N., Vandekereckhove, J., Weingart, S., Hartmann, G., Rieder, H., Fonatsch, C., Tsubouchi, H., Hishida, T., Daikuhara, Y. and Birchmeier, W. Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc. Natl. Acad. Sci. USA, 88, 7001-7005 (1991).
24. Rosen, E. M., Knesel, J., Goldberg, I. D., Jin, L., Bhargava, M., Joseph, A., Zitnik, R., Wines, J., Kelley, M. and Rockwell, S. Scatter factor modulates the metastatic phenotype of the EMT6 mouse mammary tumor. Int. J. Cancer, 57, 706-714 (1994).
25. Rong, S., Segal, S., Anver, M., Resau, J. H. and Vande Woude, G. F. Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. Proc. Natl. Acad. Sci. USA, 91, 4731-4735 (1994).
26. Nakamura, T., Nishizawa, T., Hagiya, M., Seki, T., Shimonishi, M., Sugiura, A., Tashiro, K. and Shimizu, S. Molecular cloning and expression of human hepatocyte growth factor. Nature, 342, 440-443 (1989).
27. Takahashi, M., Ota, S., Shimada, T., Hamada, E., Kawabe, T., Okudaira, T., Matsumura, M., Kaneko, N., Terano, A., Nakamura, T. and Omata, M. Hepatocyte growth factor is the most potent endogenous stimulant of rabbit gastric epithelial cell proliferation and migration in primary culture. J. Clin. Invest., 95, 1994-2003 (1995).
28. Bottaro, D. P., Rubin, J. S., Faletto, D. L., Chan, A. M.-L., Kmiecik, T. E., van de Woude, G. F. and Aaronson, S. A. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science, 251, 802-804 (1991).
29. Nardini, L., Vigna, E., Narsimhan, R., Guadino, G., Zarnegar, R., Michalopoulos, G. and Comoglio, P. M. Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto- oncogene c-MET. Oncogene, 6, 501-504 (1991).
30. Kuniyasu, H., Yasui, W., Kitadai, Y., Yokozaki, H., Ito, H. and Tahara, E. Frequent amplification of the c-met gene in scirrhous type gastric cancer. Biochem. Biophys. Res. Commun., 189, 227-232 (1992).
31. Tahara, E., Kuniyasu, H., Yasui, W. and Yokozaki, H. Abnormal expression of growth factors and their receptors in stomach cancer. Gann Monogr. Cancer Res., 42, 163- 173 (1994).
32. Lyons, R. M., Keski-Oja, J. and Moses, H. L. Proteolytic activation of latent transforming growth factor β from fibroblast conditioned medium. J. Cell Biol., 106, 1659- 1665 (1990).
33. Horimoto, M., Kato, J., Takimoto, R., Terui, T., Mogi, Y. and Niitsu, Y. Identification of a transforming growth factor-β1 activator derived from a human gastric cancer cell line. Br. J. Cancer, 72, 676-682 (1995).
34. Miyazono, K. and Heldin, C.-H. Role for carbohydrate structures in TGF-β1 latency. Nature, 338, 158-160 (1989).
35. Odekon, L. E., Blasi, F. and Rifkin, D. B. Requirement for receptor-bound urokinase in plasmin-dependent cellu- lar conversion of latent TGF-beta to TGF-beta. J. Cell. Physiol., 158, 398-407 (1994).