Conformational changes in extracellular loop 2 associated with signal transduction in the glycine receptor

Journal of Neurochemistry

Volumn 115, Issue 5, 2010, Pages 1245-1255

  Cederholm, Jennie M E ^a,b   Absalom, Nathan L ^a,c   Sugiharto, Silas ^a   Griffith, Renate ^a   Schofield, Peter R ^a,b,c   Lewis, Trevor M ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Channel gating; Extracellular domain; Glycine receptor; Loop 2; Signal transduction

Indexed keywords

COMPLEMENTARY DNA; CYSTEINE; GLYCINE RECEPTOR; GLYCINE RECEPTOR ALPHA1; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIGAND BINDING; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

BINDING SITES; CELL LINE, TRANSFORMED; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCINE; HUMANS; ION CHANNEL GATING; LIGANDS; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GLYCINE; SIGNAL TRANSDUCTION; SULFHYDRYL REAGENTS; TRANSFECTION;

EID: 78149251538     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.07021.x     Document Type: Article

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