Neuropeptide, mast cell, and myofibroblast expression after rabbit deep flexor tendon repair

Journal of Hand Surgery

Volumn 35, Issue 11, 2010, Pages 1842-1849

  Berglund, Maria E ^a,b   Hildebrand, Kevin A ^a,b   Zhang, Mei ^a,b   Hart, David A ^a,b   Wiig, Monica E ^a,b  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Flexor tendon healing; mast cell; myofibroblast; neuropeptide; TGF 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; MESSENGER RNA; NEUROPEPTIDE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FLEXOR TENDON; FLEXOR TENDON INJURY; IMMUNOHISTOCHEMISTRY; MAST CELL; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TENDON RECONSTRUCTION; TENDON SHEATH;

ANIMALS; BIOLOGICAL MARKERS; BIOPSY, NEEDLE; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MAST CELLS; MYOFIBROBLASTS; NEUROPEPTIDES; RABBITS; RANDOM ALLOCATION; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TENDON INJURIES; TENOTOMY; UP-REGULATION; WOUND HEALING;

EID: 78049470094     PISSN: 03635023     EISSN: 15316564     Source Type: Journal    
DOI: 10.1016/j.jhsa.2010.06.031     Document Type: Article

References (42)

1. D. Elliot, C.H. Barbieri, R.B. Evans, D. Mass, and J.B. Tang IFSSH flexor tendon committee report 2007 J Hand Surg 32B 2007 346 356
2. D. Huang, G. Balian, and A.B. Chhabra Tendon tissue engineering and gene transfer: the future of surgical treatment J Hand Surg 31A 2006 693 704
3. R. James, G. Kesturu, G. Balian, and A.B. Chhabra Tendon: biology, biomechanics, repair, growth factors, and evolving treatment options J Hand Surg 33A 2008 102 112
4. M.J. Silva, M.I. Boyer, and R.H. Gelberman Recent progress in flexor tendon healing J Orthop Sci 7 2002 508 514
5. W.A. Border, and N.A. Noble Transforming growth factor β in tissue fibrosis N Engl J Med 331 1994 1286 1292
6. K.A. Hildebrand, M. Zhang, N.M. Germscheid, C. Wang, and D.A. Hart Cellular, matrix and growth factor components of the joint capsule are modified early in the process of posttraumatic contracture formation in a rabbit model Acta Orthop 79 2008 116 125
7. T. Gottwald, S. Coerper, M. Schffer, G. Kveker, and R.H. Stead The mast cell-nerve axis in wound healing: a hypothesis Wound Repair Regen 6 1998 8 20
8. M. Maurer, T. Theoharides, R.D. Granstein, S.C. Bischoff, J. Bienenstock, and B. Henz What is the physiological function of mast cells? Exp Dermatol 12 2003 886 910
9. T.E. Schubert, C. Weidler, N. Borisch, C. Schubert, F. Hofstdter, and R.H. Straub Dupuytren's contracture is associated with sprouting of substance P positive nerve fibres and infiltration by mast cells Ann Rheum Dis 65 2006 414 415
10. J.R. Scott, P.R. Muangman, R.N. Tamura, K.Q. Zhu, Z. Liang, and J. Anthony Substance P levels and neutral endopeptidase activity in acute burn wounds and hypertrophic scar Plast Reconstr Surg 115 2005 1095 1102
11. G. Andersson, P. Danielson, H. Alfredson, and S. Forsgren Presence of substance P and the neurokinin-1 receptor in tenocytes of the human Achilles tendon Regul Pept 150 2008 81 87
12. Ø. Lian, J. Dahl, P.W. Ackermann, F. Frihagen, L. Engebretsen, and R. Bahr Pronociceptive and antinociceptive neuromediators in patellar tendinopathy Am J Sports Med 34 2006 1801 1808
13. T.E. Schubert, C. Weidler, K. Lerch, F. Hofstdter, and R.H. Straub Achilles tendinosis is associated with sprouting of substance P positive nerve fibres Ann Rheum Dis 64 2005 1083 1086
14. M. Berglund, D.A. Hart, and M. Wiig The inflammatory response and hyaluronan synthases in the rabbit flexor tendon and tendon sheath following injury J Hand Surg 32B 2007 581 587
15. A.E. Loiselle, G.A. Bragdon, J.A. Jacobson, S. Hasslund, Z.E. Cortes, and E.M. Schwarz Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression J Orthop Res 27 2009 833 840
16. M. Wiig, S.O. Abrahamsson, and G. Lundborg Tendon repair: cellular activities in rabbit deep flexor tendons and surrounding synovial sheaths and the effects of hyaluronan An experimental study in vivo and in vitro J Hand Surg 22A 1997 818 825
17. T. de Wit, D. de Putter, W. Tra, H.A. Rakhorst, G.J. van Osch, and S.E. Hovius Auto-crosslinked hyaluronic acid gel accelerates healing of rabbit flexor tendons in vivo J Orthop Res 27 2009 408 415
18. C. Reno, L. Marchuk, P. Sciore, C.B. Frank, and D.A. Hart Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues Biotechniques 22 1997 1082 1086
19. M. Berglund, M. Wiig, M. Torstensson, C. Reno, and D. Hart Assessment of mRNA levels for matrix molecules and TGF-β1 in rabbit flexor and peroneus tendons reveals regional differences in steady-state expression J Hand Surg 29B 2004 165 169
20. L. Marchuk, P. Sciore, C. Reno, C.B. Frank, and D.A. Hart Postmortem stability of total RNA isolated from rabbit ligament, tendon and cartilage Biochim Biophys Acta 1379 1998 171 177
21. M. Berglund, C. Reno, D.A. Hart, and M. Wiig Patterns of mRNA expression for matrix molecules and growth factors in flexor tendon injury: differences in the regulation between tendon and tendon sheath J Hand Surg 31A 2006 1279 1287
22. K.A. Hildebrand, M. Zhang, P.T. Salo, and D.A. Hart Joint capsule mast cells and neuropeptides are increased within four weeks of injury and remain elevated in chronic stages of posttraumatic contractures J Orthop Res 26 2008 1313 1319
23. K.A. Hildebrand, M. Zhang, W. van Snellenberg, G.J. King, and D.A. Hart Myofibroblast numbers are elevated in human capsules after trauma Clin Orthop Relat Res 419 2004 189 197
24. Y.F. Wu, C.H. Chen, Y. Cao, B. Avanessian, X.T. Wang, and J.B. Tang Molecular events of cellular apoptosis and proliferation in the early tendon healing period J Hand Surg 35A 2010 2 10
25. D.D. Metcalfe, D. Baram, and Y.A. Mekori Mast cells Physiol Rev 77 1997 1033 1079
26. C.L. Gallant-Behm, K.A. Hildebrand, and D.A. Hart The mast cell stabilizer ketotifen prevents development of excessive skin wound contraction and fibrosis in red Duroc pigs Wound Repair Regen 16 2008 226 233
27. A. Desmoulire, C. Chaponnier, and G. Gabbiani Tissue repair, contraction, and the myofibroblast Wound Repair Regen 13 2005 7 12
28. A. Desmoulire Factors influencing myofibroblast differentiation during wound healing and fibrosis Cell Biol Int 19 1995 471 476
29. H.F. Chiu, and R.M. McFarlane Pathogenesis of Dupuytren's contracture: a correlative clinical-pathological study J Hand Surg 3 1978 1 10
30. L.S. Verjee, K. Midwood, D. Davidson, D. Essex, A. Sandison, and J. Nanchahal Myofibroblast distribution in Dupuytren's cords: correlation with digital contracture J Hand Surg 34A 2009 1785 1794
31. H.B. Hindman, R. Marty-Roix, J.B. Tang, J.B. Jupiter, B.P. Simmons, and M. Spector Regulation of expression of α-smooth muscle actin in cells of Dupuytren's contracture J Bone Joint Surg 85B 2003 448 455
32. D. Jiang, Z. Jiang, Z. Li, and Y. Zhang Suppression of the production of extracellular matrix and α-smooth muscle actin induced by transforming growth factor-β1 in fibroblasts of the flexor tendon sheath by hepatocyte growth factor Scand J Plast Reconstr Surg 42 2008 169 173
33. M.B. Vaughan, E.W. Howard, and J.J. Tomasek Transforming growth factor-β1 promotes the morphological and functional differentiation of the myofibroblast Exp Cell Res 257 2000 180 189
34. M.A. Bisson, D.A. McGrouther, V. Mudera, and A.O. Grobbelaar The different characteristics of Dupuytren's disease fibroblasts derived from either nodule or cord: expression of α-smooth muscle actin and the response to stimulation by TGF-β1 J Hand Surg 28B 2003 351 356
35. J. Chang, D. Most, E. Stelnicki, J. Siebert, M.T. Longaker, and K. Hui Gene expression of transforming growth factor β1 in rabbit zone II flexor tendon wound healing: evidence for dual mechanisms of repair Plast Reconstr Surg 100 1997 937 944
36. C.H. Chen, Y. Cao, Y.F. Wu, A.J. Bais, J.S. Gao, and J.B. Tang Tendon healing in vivo: gene expression and production of multiple growth factors in early tendon healing period J Hand Surg 33A 2008 1834 1842
37. J. Chang, R. Thunder, D. Most, M.T. Longaker, and W.C. Lineaweaver Studies in flexor tendon wound healing: neutralizing antibody to TGF-β1 increases postoperative range of motion Plast Reconstr Surg 105 2000 148 155
38. S.J. Bates, E. Morrow, A.Y. Zhang, H. Pham, M.T. Longaker, and J. Chang Mannose-6-phosphate, an inhibitor of transforming growth factor-beta, improves range of motion after flexor tendon repair J Bone Joint Surg 88A 2006 2465 2472
39. C. Zhao, M.E. Zobitz, Y.L. Sun, K.S. Predmore, P.C. Amadio, and K.N. An Surface treatment with 5-fluorouracil after flexor tendon repair in a canine in vivo model J Bone Joint Surg 91A 2009 2673 2682
40. R. Ragoowansi, U. Khan, R.A. Brown, and D.A. McGrouther Differences in morphology, cytoskeletal architecture and protease production between zone II tendon and synovial fibroblasts in vitro J Hand Surg 28B 2003 465 470
41. A.E. Steyaert, P.J. Burssens, C.W. Vercruysse, G.G. Vanderstraeten, and R.M. Verbeeck The effects of substance P on the biomechanic properties of ruptured rat Achilles' tendon Arch Phys Med Rehabil 87 2006 254 258
42. J. Parreno, and D.A. Hart Molecular and mechano-biology of collagen gel contraction mediated by human MG-63 cells: involvement of specific intracellular signaling pathways and the cytoskeleton Biochem Cell Biol 87 2009 895 904