Mannose-6-phosphate, an inhibitor of transforming growth factor-β, improves range of motion after flexor tendon repair

Journal of Bone and Joint Surgery

Volumn 88, Issue 11, 2006, Pages 2465-2472

  Bates, Steven J ^a   Morrow, Ellen ^a   Zhang, Andrew Y ^a   Pham, Hung ^a   Longaker, Michael T ^a   Chang, James ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; DECORIN; ENROFLOXACIN; MANNOSE 6 PHOSPHATE; PHOSPHATE BUFFERED SALINE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENDOTENON; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITENON; FLEXOR TENDON; FOREFOOT; HAND MOVEMENT; IN VITRO STUDY; IN VIVO CULTURE; LOW DRUG DOSE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RABBIT; RANGE OF MOTION; SCAR FORMATION; TENDON RECONSTRUCTION; TENDON SHEATH;

EID: 33750823075     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/JBJS.E.00143     Document Type: Article

References (36)

1. Lundborg G, Rank F. Experimental intrinsic healing of flexor tendons based on synovial fluid nutrition. J Hand Surg [Am]. 1978;3:21-31.
2. Furlow LT Jr. The role of tendon tissues in tendon healing. Plast Reconstr Surg. 1976;57:39-49.
3. Potenza AD. Tendon healing within the flexor digital sheath in the dog. J Bone Joint Surg Am. 1962;44:49-64.
4. Manske PR, Lesker PA. Biochemical evidence of flexor tendon participation in the repair process-an in vitro study. J Hand Surg [Br]. 1984;9:117-20.
5. Gelberman RH, Manske PR, Vande Berg JS, Lesker PA, Akeson WH. Flexor tendon repair in vitro: comparative histologic study of the rabbit, chicken, dog, and monkey. J Orthop Res. 1984;2:39-48.
6. Gonzalez RI. Experimental tendon repair within the flexor tunnels: use of polyethylene tubes for improvement of functional results in the dog. Surgery. 1949;26:181-98.
7. Kapetanos G. The effect of the local corticosteroids on the healing and biochemical properties of the partially injured tendon. Clin Orthop Relat Res. 1982;163:170-9.
8. Herzog M, Lindsay WK, McCain WG. Effect of beta-aminoproprionitrile on adhesions following digital flexor tendon repair in chickens. Surg Forum. 1970;21:509-11.
9. Albrechtsen SJ, Harvey JS Jr. Dimethyl sulfoxide. Biomechanical effects on tendons. Am J Sports Med. 1982;10:177-9.
10. Amiel D, Ishizue K, Billings E Jr, Wiig M, Vande Berg J, Akeson WH, Gelberman R. Hyaluronan in flexor tendon repair. J Hand Surg [Am]. 1989;14:837-43.
11. Salti NI, Tuel RJ, Mass DP Effect of hyaluronic acid on rabbit profundus flexor tendon healing in vitro. J Surg Res. 1993;55:411-5.
12. Thomas SC, Jones LC, Hungerford DS. Hyaluronic acid and its effect on post-operative adhesions in the rabbit flexor tendon. A preliminary look. Clin Orthop Relat Res. 1986;206:281-9.
13. Bennett NT, Schultz GS. Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am J Surg. 1993;165:728-37.
14. Folkman J, Klagsbrun M. Angiogenic factors. Science. 1987;235:442-7.
15. Sporn MB, Roberts AB. Transforming growth factor-beta: recent progress and new challenges. J Cell Biol. 1992;119:1017-21.
16. Massague J, Chen YG. Controlling TGF-beta signaling. Genes Dev. 2000;14:627-44.
17. Kulozik M, Hogg A, Lankat-Buttgereit B, Krieg T. Co-localization of transforming growth factor beta 2 with alpha 1(1) procollagen mRNA in tissue sections of patients with systemic sclerosis. J Clin Invest. 1990;86:917-22.
18. Peltonen J, Kahari L, Jaakkola S, Kahari VM, Varga J, Uitto J, Jimenez SA. Evaluation of transforming growth factor beta and type I procollagen gene expression in fibrotic skin diseases by in situ hybridization. J Invest Dermatol. 1990;94:365-71.
19. Ghahary A, Shen YJ, Scott PG, Gong Y, Tredget EE. Enhanced expression of mRNA for transforming growth factor-beta, type I and type III procollagen in human post-burn hypertrophic scar tissues. J Lab Clin Med. 1993;122:465-73.
20. Peltonen J, Hsiao LL, Jaakkola S, Sollberg S, Aumailley M, Timpl R, Chu ML, Uitto J. Activation of collagen gene expression in keloids: co-localization of type I and VI collagen and transforming growth factor-beta 1 mRNA. J Invest Dermatol. 1991;97:240-8.
21. Shah M, Foreman DM, Ferguson MW. Neutralizing antibody to TGF-beta 1,2 reduces cutaneous scarring in adult rodents. J Cell Sci. 1994;107:1137-57.
22. Border WA, Noble NA, Yamamoto T, Harper JR, Yamaguchi Y, Pierschbacher MD, Ruoslahti E. Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease. Nature. 1992;360:361-4.
23. Markmann A, Hausser H, Schonherr E, Kresse H. Influence of decorin expression on transforming growth factor-beta-mediated collagen gel retraction and biglycan induction. Matrix Biol. 2000;19:631-6.
24. Logan A, Berry M. Transforming growth factor-beta 1 and basic fibroblast growth factor in the injured CNS. Trends Pharmacol Sci. 1993;14:337-42.
25. Dennis PA, Rifkin DB. Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc Natl Acad Sci USA. 1991;88:580-4.
26. Roberts AB, Sporn MB. Transforming growth factor-beta. In: Clark RA, editor. The molecular and cellular biology of wound repair. 2nd ed. New York: Plenum; 1996. p 275-98.
27. Klein MB, Yalamanchi N, Pham H, Longaker MT, Chang J. Flexor tendon wound healing in vitro: effects of TGF-beta on tendon cell collagen production. J Hand Surg [Am]. 2002;27:615-20.
28. Zhang AY, Pham H, Ho F, Teng K, Longaker MT, Chang J. Inhibition of TGF-beta-induced collagen production in rabbit flexor tendons. J Hand Surg [Am]. 2004;29:230-5.
29. Chang J, Most D, Stelnicki E, Siebert JW, Longaker MT, Hui K, Lineaweaver WC. Gene expression of transforming growth factor beta-1 in rabbit zone II flexor tendon wound healing: evidence for dual mechanisms of repair. Plast Reconstr Surg. 1997;100:937-94.
30. Ngo M, Pham H, Longaker MT, Chang J. Differential expression of transforming growth factor-beta receptors in a rabbit zone II flexor tendon wound healing model. Plast Reconstr Surg. 2001;108:1260-7.
31. Chang J, Thunder R, Most D, Longaker MT, Lineaweaver WC. Studies in flexor tendon wound healing: neutralizing antibody to TGF-beta1 increases postoperative range of motion. Plast Reconstr Surg. 2000;105:148-55.
32. Thunder RM, Chang J, Broome RL, Most D. A method for immobilizing the forelimbs of rabbits. Contemp Top Lab Anim Sci. 1998;37:94-5.
33. Fukui N, Fukuda A, Kojima K, Nakajima K, Oda H, Nakamura K. Suppression of fibrous adhesions by proteoglycan decorin. J Orthop Res. 2001;19:456-62.
34. Yamaguchi Y, Mann DM, Ruoslahti E. Negative regulation of transforming growth factor-beta by the proteoglycan decorin. Nature. 1990;346:281-4.
35. Kresse H, Schonherr E. Proteoglycans of the extracellular matrix and growth control. J Cell Physiol. 2001;189:266-74.
36. Dennis PA, Rifkin DB. Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose-6-phosphate/ insulin-like growth factor type II receptor. Proc Natl Acad Sci USA. 1991;88:580-4.