Substance P levels and neutral endopeptidase activity in acute burn wounds and hypertrophic scar

Plastic and Reconstructive Surgery

Volumn 115, Issue 4, 2005, Pages 1095-1102

  Scott, Jeffrey R ^a,b   Muangman, Pornprom R ^a,b   Tamura, Richard N ^a,b   Zhu, Kathy Q ^a,b   Liang, Zhi ^a,b   Anthony, Joanne ^a,b   Engrav, Loren H ^a,b   Gibran, Nicole S ^a,b,c  

^a University of Washington ^*

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; BICINCHONINIC ACID; CINCHONINE; MEMBRANE METALLOENDOPEPTIDASE; METHOXY 2 NAPHTHYLAMINE; SUBSTANCE P; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; BURN; CHILD; CLINICAL ARTICLE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REGULATION; FEMALE; HISTOPATHOLOGY; HUMAN; HYPERTROPHIC SCAR; MALE; MEDIATOR RELEASE; MEMBRANE BINDING; PERIPHERAL NERVE; PRIORITY JOURNAL; SAMPLING; SKIN INJURY; WOUND HEALING;

ADOLESCENT; ADULT; AGED; BURNS; CHILD; CHILD, PRESCHOOL; CICATRIX, HYPERTROPHIC; ENDOPEPTIDASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MIDDLE AGED; REAGENT KITS, DIAGNOSTIC; SUBSTANCE P; WOUND HEALING;

EID: 16344378605     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.PRS.0000156151.54042.DA     Document Type: Article

References (35)

1. Parks, D. H. Late problems in burns. Clin. Plast. Surg. 4: 547, 1977.
2. Peltonen, J., Hsiao, L. L., Jaakkola, S., et al. Activation of collagen gene expression in keloids: Co-localization of type I and VI collagen and transforming growth factor-beta 1 mRNA. J. Invest. Dermatol. 97: 240, 1991.
3. Goretsky, M. J., Harriger, M. D., Supp, A. P., et al. Expression of interleukin-1 alpha, interleukin-6, and basic fibroblast growth factor by cultured skin substitutes before and after grafting to full-thickness wounds in athymic mice. J. Trauma 40: 894, 1996.
4. Lepisto, J., Laato, M., Niinikoski, J., et al. Effects of homodimeric isoforms of platelet-derived growth factor (PDGF-AA and PDGF-BB) on wound healing in rat. Surg. Res. 53: 596, 1992.
5. Pierce, G. F., Tarpley, J. E., Yanagihara, D., et al. Platelet-derived growth factor (BB homodimer), transforming growth factor-beta 1, and basic fibroblast growth factor in dermal wound healing: Neovessel and matrix formation and cessation of repair. Am. J. Pathol. 140: 1375, 1992.
6. Lawrence, W. T., and Diegelmann, R. F. Growth factors in wound healing. Clin. Dermatol. 12: 157, 1994.
7. Xu, S., Bao, W., Chen, D., and Wang, Q. The characters of proliferating activity and biosynthetic function of fibroblasts from abnormal scars after complete contact in vitro (in Chinese). Zhonghua Zheng Xing Wai Ke Za Zhi 18: 86, 2002.
8. Castagnoli, C., Trombotto, C., Ondei, S., et al. Characterization of T-cell subsets infiltrating post-burn hypertrophic scar tissues. Burns 23: 565, 1997.
9. Kischer, C. W., and Bailey, J. F. The mast cell in hypertrophic scars. Tex. Rep. Biol. Med. 30: 327, 1972.
10. Kupietzky, A., and Levi-Schaffer, F. The role of mast cell-derived histamine in the closure of an in vitro wound. Inflamm. Res. 45: 176, 1996.
11. Cracco, C., Stella, M., Teich, A. S., and Filogamo, G. Comparative study of Langerhans cells in normal and pathological human scars: II. Hypertrophic scars. Eur. J. Histochem. 36: 53, 1992.
12. Zhang, L. Q., and Laato, M. Innervation of normal and hypertrophic human scars and experimental wounds in the rat. Ann. Chir. Gynaecol. 90 (Suppl. 215): 29, 2001.
13. Crowe, R., Parkhouse, N., McGrouther, D., and Burnstock, G. Neuropeptide-containing nerves in painful hypertrophic human scar tissue. Br. J. Dermatol. 130: 444, 1994.
14. Liang, Z. E. L., Muangman, P., Muffley, L. A., et al. Nerve quantification in female, red Duroc pig (FDRP) scar compared to human hypertrophic scar. Burns 30: 57, 2004.
15. Gibran, N. S., Jang, Y. C., Isik, F. F., et al. Diminished neuropeptide levels contribute to the impaired cutaneous healing response associated with diabetes mellitus. J. Surg. Res. 108: 122, 2002.
16. Dunnick, C., Gibran, N., and Heimbach, D. M. Substance P has a role in neurogenic mediation of burn wound healing. J. Burn Care Rehabil 17: 390, 1996.
17. Iwamoto, I., Ueki, I. F., Borson, D. B., and Nadel, J. A. Neutral endopeptidase modulates tachykinin-induced increase in vascular permeability in guinea pig skin. Int. Arch. Allergy Appl. Immunol. 88: 288, 1989.
18. Holzer, P. Neurogenic vasodilatation and plasma leakage in the skin. Gen. Pharmacol. 30: 5, 1998.
19. Hughes, S., Williams, T., and Brain, S. Evidence that endogenous nitric oxide modulates oedema formation induced by substance P. Eur. J. Pharmacol. 191: 481, 1990.
20. Zhao, D., Kuhnt-Moore, S., Zeng, H., et al. Substance P-stimulated interleukin-8 expression in human co-Ionic epithelial cells involves Rho family small GT-Pases. Biochem. J. 368: 665, 2002.
21. Weidner, C., Klede, M., Rukwied, R., et al. Acute effects of substance P and calcitonin gene-related peptide in human skin: A microdialysis study. J. Invest. Dermatol. 115: 1015, 2000.
22. Helme, R. D., Eglezos, A., and Hosking, C. S. Substance P induces chemotaxis of neutrophils in normal and capsaicin-treated rats. Immunol. Cell Biol. 65: 267, 1987.
23. Scott, J. R., Muangman, P., Anthony, J., and Gibran, N. Topical substance P increases macrophage and leukocyte density in the healing wound. Unpublished data, 2002.
24. Roch-Arveiller, M., Regoli, D., Chanaud, B., et al. Tachykinins: Effects on motility and metabolism of rat polymorphonuclear leucocytes. Pharmacology 33: 266, 1986.
25. Carolan, E. J., and Casale, T. B. Effects of neuropeptides on neutrophil migration through noncellular and endothelial barriers. J. Allergy Clin. Immunol. 92: 589, 1993.
26. Ziehe, M., Morbidelli, L., Pacini, M., et al. Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells. Microvasc. Res. 40: 264, 1990.
27. Kahler, C. M., Herold, M., Reinisch, N., and Wiedermann, C. J. Interaction of substance P with epidermal growth factor and fibroblast growth factor in cyclooxygenase-dependent proliferation of human skin fibroblasts. J. Cell. Physiol. 166: 601, 1996.
28. Kahler, C. M., Herold, M., and Wiedermann, C. J. Substance P: A competence factor for human fibroblast proliferation that induces the release of growth-regulatory arachidonic acid metabolites. J. Cell. Physiol. 156: 579, 1993.
29. Roques, B. P., Noble, F., Dauge, V., et al. Neutral endopeptidase 24.11: Structure, inhibition, and experimental and clinical pharmacology. Pharmacol. Rev. 45: 87, 1993.
30. Graf, K., Kunkel, K., Zhang, M., et al. Activation of adenylate cyclase and phosphodiesterase inhibition enhance neutral endopeptidase activity in human endothelial cells. Peptides 16: 1273, 1995.
31. Olerud, J. E., Usui, M. L., Seckin, D., et al. Neutral endopeptidase expression and distribution in human skin and wounds. J. Invest. Dermatol. 112: 873, 1999.
32. Spenny, M. L., Muangman, P., Sullivan, S. R., et al. Neutral endopeptidase inhibition in diabetic wound repair. Wound Repair Regen. 10: 295, 2002.
33. Terashima, H., Okamoto, A., Menozzi, D., et al. Identification of neuropeptide-degrading enzymes in the pancreas. Peptides 13: 741, 1992.
34. Liang, X. E. L. Unpublished observations, 2003.
35. Wajima, Z., Hua, X. Y., and Yaksh, T. L. Inhibition of spinal protein kinase C blocks substance P-mediated hyperalgesia. Brain Res. 877: 314, 2000.