메뉴 건너뛰기




Volumn 12, Issue 6, 2010, Pages 537-551

Metabolome, transcriptome and metabolic flux analysis of arabinose fermentation by engineered Saccharomyces cerevisiae

Author keywords

Arabinose; Evolutionary engineering; Metabolic flux analysis; Metabolomics; Saccharomyces cerevisiae; Transcriptomics

Indexed keywords

ARABINOSE; EVOLUTIONARY ENGINEERING; METABOLIC FLUX ANALYSIS; METABOLOMICS; SACCHAROMYCES CEREVISIAE; TRANSCRIPTOMICS;

EID: 78049451371     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2010.08.003     Document Type: Article
Times cited : (69)

References (79)
  • 2
    • 33947493105 scopus 로고    scopus 로고
    • Hxk2 regulates the phosphorylation state of Mig1 and therefore its nucleocytoplasmic distribution
    • Ahuatzi D., Riera A., Pelaez R., Herrero P., Moreno F. Hxk2 regulates the phosphorylation state of Mig1 and therefore its nucleocytoplasmic distribution. J. Biol. Chem. 2007, 282:4485-4493.
    • (2007) J. Biol. Chem. , vol.282 , pp. 4485-4493
    • Ahuatzi, D.1    Riera, A.2    Pelaez, R.3    Herrero, P.4    Moreno, F.5
  • 3
    • 0002587184 scopus 로고
    • Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for growth in a defined medium
    • Andreasen A.A., Stier T.J. Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for growth in a defined medium. J. Cell Physiol. 1953, 41:23-36.
    • (1953) J. Cell Physiol. , vol.41 , pp. 23-36
    • Andreasen, A.A.1    Stier, T.J.2
  • 4
    • 0000493179 scopus 로고
    • Anaerobic nutrition of Saccharomyces cerevisiae. II. Unsaturated fatty acid requirement for growth in a defined medium
    • Andreasen A.A., Stier T.J. Anaerobic nutrition of Saccharomyces cerevisiae. II. Unsaturated fatty acid requirement for growth in a defined medium. J. Cell Physiol. 1954, 43:271-281.
    • (1954) J. Cell Physiol. , vol.43 , pp. 271-281
    • Andreasen, A.A.1    Stier, T.J.2
  • 5
    • 0034071629 scopus 로고    scopus 로고
    • Metabolic engineering applications to renewable resource utilization
    • Aristidou A., Penttilä M. Metabolic engineering applications to renewable resource utilization. Curr. Opin. Biotechnol. 2000, 11:187-198.
    • (2000) Curr. Opin. Biotechnol. , vol.11 , pp. 187-198
    • Aristidou, A.1    Penttilä, M.2
  • 6
    • 0034100041 scopus 로고    scopus 로고
    • Glucose depletion rapidly inhibits translation initiation in yeast
    • Ashe M.P., De Long S.K., Sachs A.B. Glucose depletion rapidly inhibits translation initiation in yeast. Mol. Biol. Cell 2000, 11:833-848.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 833-848
    • Ashe, M.P.1    De Long, S.K.2    Sachs, A.B.3
  • 7
    • 0014353859 scopus 로고
    • Energy charge of adenylate pool as a regulatory parameter. Interaction with feedback modifiers
    • Atkinson D.E. Energy charge of adenylate pool as a regulatory parameter. Interaction with feedback modifiers. Biochemistry 1968, 7:4030-4034.
    • (1968) Biochemistry , vol.7 , pp. 4030-4034
    • Atkinson, D.E.1
  • 8
    • 0037962155 scopus 로고    scopus 로고
    • A modified Saccharomyces cerevisiae strain that consumes l-arabinose and produces ethanol
    • Becker J., Boles E. A modified Saccharomyces cerevisiae strain that consumes l-arabinose and produces ethanol. Appl. Environ. Microbiol. 2003, 69:4144-4150.
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 4144-4150
    • Becker, J.1    Boles, E.2
  • 10
    • 77955555768 scopus 로고    scopus 로고
    • Establishment of l-arabinose fermentation in glucose/xylose co-fermenting recombinant Saccharomyces cerevisiae 424A(LNH-ST) by genetic engineering. Appl. Microbiol. Biotechnol.
    • Bera, A.K., Sedlak, M., Khan, A., Ho, N.W., 2010. Establishment of l-arabinose fermentation in glucose/xylose co-fermenting recombinant Saccharomyces cerevisiae 424A(LNH-ST) by genetic engineering. Appl. Microbiol. Biotechnol.
    • (2010)
    • Bera, A.K.1    Sedlak, M.2    Khan, A.3    Ho, N.W.4
  • 11
    • 68949213819 scopus 로고    scopus 로고
    • Arabinose and xylose fermentation by recombinant Saccharomyces cerevisiae expressing a fungal pentose utilization pathway
    • Bettiga M., Bengtsson O., Hahn-Hägerdal B., Gorwa-Grauslund M.F. Arabinose and xylose fermentation by recombinant Saccharomyces cerevisiae expressing a fungal pentose utilization pathway. Microb. Cell Fact. 2009, 8:40.
    • (2009) Microb. Cell Fact. , vol.8 , pp. 40
    • Bettiga, M.1    Bengtsson, O.2    Hahn-Hägerdal, B.3    Gorwa-Grauslund, M.F.4
  • 12
    • 0026651864 scopus 로고
    • Overproduction of the Gal1 or Gal3 protein causes galactose-independent activation of the Gal4 protein-evidence for a new model of induction for the yeast Gal Mel regulon
    • Bhat P.J., Hopper J.E. Overproduction of the Gal1 or Gal3 protein causes galactose-independent activation of the Gal4 protein-evidence for a new model of induction for the yeast Gal Mel regulon. Mol. Cell. Biol. 1992, 12:2701-2707.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2701-2707
    • Bhat, P.J.1    Hopper, J.E.2
  • 13
    • 0037474301 scopus 로고    scopus 로고
    • The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur
    • Boer V.M., de Winde J.H., Pronk J.T., Piper M.D. The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J. Biol. Chem. 2003, 278:3265-3274.
    • (2003) J. Biol. Chem. , vol.278 , pp. 3265-3274
    • Boer, V.M.1    de Winde, J.H.2    Pronk, J.T.3    Piper, M.D.4
  • 14
    • 0030971548 scopus 로고    scopus 로고
    • Characterization of a glucose-repressed pyruvate kinase (Pyk2p) in Saccharomyces cerevisiae that is catalytically insensitive to fructose-1,6-bisphosphate
    • Boles E., Schulte F., Miosga T., Freidel K., Schlüter E., Zimmermann F.K., Hollenberg C.P., Heinisch J.J. Characterization of a glucose-repressed pyruvate kinase (Pyk2p) in Saccharomyces cerevisiae that is catalytically insensitive to fructose-1,6-bisphosphate. J. Bacteriol. 1997, 179:2987-2993.
    • (1997) J. Bacteriol. , vol.179 , pp. 2987-2993
    • Boles, E.1    Schulte, F.2    Miosga, T.3    Freidel, K.4    Schlüter, E.5    Zimmermann, F.K.6    Hollenberg, C.P.7    Heinisch, J.J.8
  • 15
    • 0022606970 scopus 로고
    • The interdependence of glycolytic and pentose cycle intermediates in ad libitum fed rats
    • Casazza J.P., Veech R.L. The interdependence of glycolytic and pentose cycle intermediates in ad libitum fed rats. J. Biol. Chem. 1986, 261:690-698.
    • (1986) J. Biol. Chem. , vol.261 , pp. 690-698
    • Casazza, J.P.1    Veech, R.L.2
  • 16
    • 69749094421 scopus 로고    scopus 로고
    • A comprehensive method for the quantification of the non-oxidative pentose phosphate pathway intermediates in Saccharomyces cerevisiae by GC-IDMS
    • Cipollina C., ten Pierick A., Canelas A., Seifar R.M., van Maris A.J.A., Van Dam J.C., Heijnen J.J. A comprehensive method for the quantification of the non-oxidative pentose phosphate pathway intermediates in Saccharomyces cerevisiae by GC-IDMS. J. Chromatogr. B 2009, 877:3231-3236.
    • (2009) J. Chromatogr. B , vol.877 , pp. 3231-3236
    • Cipollina, C.1    ten Pierick, A.2    Canelas, A.3    Seifar, R.M.4    van Maris, A.J.A.5    Van Dam, J.C.6    Heijnen, J.J.7
  • 18
    • 1542350073 scopus 로고    scopus 로고
    • Role of transcriptional regulation in controlling fluxes in central carbon metabolism of Saccharomyces cerevisiae. A chemostat culture study
    • Daran-Lapujade P., Jansen M.L., Daran J.M., van Gulik W., de Winde J.H., Pronk J.T. Role of transcriptional regulation in controlling fluxes in central carbon metabolism of Saccharomyces cerevisiae. A chemostat culture study. J. Biol. Chem. 2004, 279:9125-9138.
    • (2004) J. Biol. Chem. , vol.279 , pp. 9125-9138
    • Daran-Lapujade, P.1    Jansen, M.L.2    Daran, J.M.3    van Gulik, W.4    de Winde, J.H.5    Pronk, J.T.6
  • 19
    • 0020564055 scopus 로고
    • Nucleotide pools of growing, synchronized and stressed cultures of Saccharomyces cerevisiae
    • Ditzelmüller G., Wöhrer W., Kubicek C.P., Röhr M. Nucleotide pools of growing, synchronized and stressed cultures of Saccharomyces cerevisiae. Arch. Microbiol. 1983, 135:63-67.
    • (1983) Arch. Microbiol. , vol.135 , pp. 63-67
    • Ditzelmüller, G.1    Wöhrer, W.2    Kubicek, C.P.3    Röhr, M.4
  • 20
    • 0037167490 scopus 로고    scopus 로고
    • Physiological role of soluble fumarate reductase in redox balancing during anaerobiosis in Saccharomyces cerevisiae
    • Enomoto K., Arikawa Y., Muratsubaki H. Physiological role of soluble fumarate reductase in redox balancing during anaerobiosis in Saccharomyces cerevisiae. FEMS Microbiol. Lett. 2002, 215:103-108.
    • (2002) FEMS Microbiol. Lett. , vol.215 , pp. 103-108
    • Enomoto, K.1    Arikawa, Y.2    Muratsubaki, H.3
  • 21
    • 0030712874 scopus 로고    scopus 로고
    • Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions
    • Fernandes L., Rodrigues-Pousada C., Struhl K. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol. Cell Biol. 1997, 17:6982-6993.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 6982-6993
    • Fernandes, L.1    Rodrigues-Pousada, C.2    Struhl, K.3
  • 22
    • 0742304300 scopus 로고    scopus 로고
    • The importance of a functional trehalose biosynthetic pathway for the life of yeasts and fungi
    • Gancedo C., Flores C.L. The importance of a functional trehalose biosynthetic pathway for the life of yeasts and fungi. FEMS Yeast Res. 2004, 4:351-359.
    • (2004) FEMS Yeast Res. , vol.4 , pp. 351-359
    • Gancedo, C.1    Flores, C.L.2
  • 23
    • 0036270543 scopus 로고    scopus 로고
    • Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method
    • Gietz R.D., Woods R.A. Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. Methods Enzymol. 2002, 350:87-96.
    • (2002) Methods Enzymol. , vol.350 , pp. 87-96
    • Gietz, R.D.1    Woods, R.A.2
  • 26
    • 0037088811 scopus 로고    scopus 로고
    • A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast
    • Güldener U., Heinisch J., Koehler G.J., Voss D., Hegemann J.H. A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast. Nucleic Acids Res. 2002, 30:e23.
    • (2002) Nucleic Acids Res. , vol.30
    • Güldener, U.1    Heinisch, J.2    Koehler, G.J.3    Voss, D.4    Hegemann, J.H.5
  • 28
    • 0036738179 scopus 로고    scopus 로고
    • Characterization of the xylose-transporting properties of yeast hexose transporters and their influence on xylose utilization
    • Hamacher T., Becker J., Gardonyi M., Hahn-Hägerdal B., Boles E. Characterization of the xylose-transporting properties of yeast hexose transporters and their influence on xylose utilization. Microbiology 2002, 148:2783-2788.
    • (2002) Microbiology , vol.148 , pp. 2783-2788
    • Hamacher, T.1    Becker, J.2    Gardonyi, M.3    Hahn-Hägerdal, B.4    Boles, E.5
  • 30
    • 58149316581 scopus 로고    scopus 로고
    • The crystal structure and identification of NQM1/YGR043C, a transaldolase from Saccharomyces cerevisiae
    • Huang H., Rong H., Li X., Tong S., Zhu Z., Niu L., Teng M. The crystal structure and identification of NQM1/YGR043C, a transaldolase from Saccharomyces cerevisiae. Proteins 2008, 73:1076-1081.
    • (2008) Proteins , vol.73 , pp. 1076-1081
    • Huang, H.1    Rong, H.2    Li, X.3    Tong, S.4    Zhu, Z.5    Niu, L.6    Teng, M.7
  • 31
    • 1242264261 scopus 로고    scopus 로고
    • Metabolic engineering for improved fermentation of pentoses by yeasts
    • Jeffries T.W., Jin Y.S. Metabolic engineering for improved fermentation of pentoses by yeasts. Appl. Microbiol. Biotechnol. 2004, 63:495-509.
    • (2004) Appl. Microbiol. Biotechnol. , vol.63 , pp. 495-509
    • Jeffries, T.W.1    Jin, Y.S.2
  • 32
    • 0036208491 scopus 로고    scopus 로고
    • Reduced oxidative pentose phosphate pathway flux in recombinant xylose-utilizing Saccharomyces cerevisiae strains improves the ethanol yield from xylose
    • Jeppsson M., Johansson B., Hahn-Hägerdal B., Gorwa-Grauslund M.F. Reduced oxidative pentose phosphate pathway flux in recombinant xylose-utilizing Saccharomyces cerevisiae strains improves the ethanol yield from xylose. Appl. Environ. Microbiol. 2002, 68:1604-1609.
    • (2002) Appl. Environ. Microbiol. , vol.68 , pp. 1604-1609
    • Jeppsson, M.1    Johansson, B.2    Hahn-Hägerdal, B.3    Gorwa-Grauslund, M.F.4
  • 33
    • 8744293844 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae engineered for xylose metabolism exhibits a respiratory response
    • Jin Y.S., Laplaza J.M., Jeffries T.W. Saccharomyces cerevisiae engineered for xylose metabolism exhibits a respiratory response. Appl. Environ. Microbiol. 2004, 70:6816-6825.
    • (2004) Appl. Environ. Microbiol. , vol.70 , pp. 6816-6825
    • Jin, Y.S.1    Laplaza, J.M.2    Jeffries, T.W.3
  • 34
    • 26244452731 scopus 로고    scopus 로고
    • 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence
    • 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence. FEBS J. 2005, 272:4970-4982.
    • (2005) FEBS J. , vol.272 , pp. 4970-4982
    • Kleijn, R.J.1    van Winden, W.A.2    van Gulik, W.M.3    Heijnen, J.J.4
  • 36
    • 0027395082 scopus 로고
    • Xylose fermentation by Saccharomyces cerevisiae
    • Kötter P., Ciriacy M. Xylose fermentation by Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 1993, 38:776-783.
    • (1993) Appl. Microbiol. Biotechnol. , vol.38 , pp. 776-783
    • Kötter, P.1    Ciriacy, M.2
  • 37
    • 0014848054 scopus 로고
    • Galactose transport in Saccharomyces cerevisiae II. Characteristics of galactose uptake and exchange in galactokinaseless cells
    • Kou S.C., Christensen M.S., Cirillo V.P. Galactose transport in Saccharomyces cerevisiae II. Characteristics of galactose uptake and exchange in galactokinaseless cells. J. Bacteriol. 1970, 103:671-678.
    • (1970) J. Bacteriol. , vol.103 , pp. 671-678
    • Kou, S.C.1    Christensen, M.S.2    Cirillo, V.P.3
  • 38
    • 76649127721 scopus 로고    scopus 로고
    • Phylogenetic analysis of ascomycete yeasts that form coenzyme Q-9 and the proposal of the new genera Babjeviella, Meyerozyma, Millerozyma, Priceomyces, and Scheffersomyces
    • Kurtzman C.P., Suzuki M. Phylogenetic analysis of ascomycete yeasts that form coenzyme Q-9 and the proposal of the new genera Babjeviella, Meyerozyma, Millerozyma, Priceomyces, and Scheffersomyces. Mycoscience 2010, 51:2-14.
    • (2010) Mycoscience , vol.51 , pp. 2-14
    • Kurtzman, C.P.1    Suzuki, M.2
  • 39
    • 13244262739 scopus 로고    scopus 로고
    • Metabolic engineering of a xylose-isomerase-expressing Saccharomyces cerevisiae strain for rapid anaerobic xylose fermentation
    • Kuyper M., Hartog M.M., Toirkens M.J., Almering M.J., Winkler A.A., van Dijken J.P., Pronk J.T. Metabolic engineering of a xylose-isomerase-expressing Saccharomyces cerevisiae strain for rapid anaerobic xylose fermentation. FEMS Yeast Res. 2005, 5:399-409.
    • (2005) FEMS Yeast Res. , vol.5 , pp. 399-409
    • Kuyper, M.1    Hartog, M.M.2    Toirkens, M.J.3    Almering, M.J.4    Winkler, A.A.5    van Dijken, J.P.6    Pronk, J.T.7
  • 40
    • 21744438324 scopus 로고    scopus 로고
    • Evolutionary engineering of mixed-sugar utilization by a xylose-fermenting Saccharomyces cerevisiae strain
    • Kuyper M., Toirkens M.J., Diderich J.A., Winkler A.A., van Dijken J.P., Pronk J.T. Evolutionary engineering of mixed-sugar utilization by a xylose-fermenting Saccharomyces cerevisiae strain. FEMS Yeast Res. 2005, 5:925-934.
    • (2005) FEMS Yeast Res. , vol.5 , pp. 925-934
    • Kuyper, M.1    Toirkens, M.J.2    Diderich, J.A.3    Winkler, A.A.4    van Dijken, J.P.5    Pronk, J.T.6
  • 41
    • 78049446539 scopus 로고    scopus 로고
    • Quantitative physiology of S. cerevisiae using metabolic network analysis. Ph.D. Thesis, Delft University of Technology, Department of Biotechnology, the Netherlands.
    • Lange, H.C., 2002. Quantitative physiology of S. cerevisiae using metabolic network analysis. Ph.D. Thesis, Delft University of Technology, Department of Biotechnology, the Netherlands.
    • (2002)
    • Lange, H.C.1
  • 43
    • 37349079028 scopus 로고    scopus 로고
    • A metabolome study of the steady-state relation between central metabolism, amino acid biosynthesis and penicillin production in Penicillium chrysogenum
    • Nasution U., van Gulik W.M., Ras C., Proell A., Heijnen J.J. A metabolome study of the steady-state relation between central metabolism, amino acid biosynthesis and penicillin production in Penicillium chrysogenum. Metab. Eng. 2008, 10:10-23.
    • (2008) Metab. Eng. , vol.10 , pp. 10-23
    • Nasution, U.1    van Gulik, W.M.2    Ras, C.3    Proell, A.4    Heijnen, J.J.5
  • 44
    • 0031015551 scopus 로고    scopus 로고
    • Flux distributions in anaerobic, glucose-limited continuous cultures of Saccharomyces cerevisiae
    • Nissen T.L., Schulze U., Nielsen J., Villadsen J. Flux distributions in anaerobic, glucose-limited continuous cultures of Saccharomyces cerevisiae. Microbiology 1997, 143:203-218.
    • (1997) Microbiology , vol.143 , pp. 203-218
    • Nissen, T.L.1    Schulze, U.2    Nielsen, J.3    Villadsen, J.4
  • 45
    • 0031041461 scopus 로고    scopus 로고
    • Metabolic and regulatory changes associated with growth of Saccharomyces cerevisiae in 1.4m NaCl-evidence for osmotic induction of glycerol dissimilation via the dihydroxyacetone pathway
    • Norbeck J., Blomberg A. Metabolic and regulatory changes associated with growth of Saccharomyces cerevisiae in 1.4m NaCl-evidence for osmotic induction of glycerol dissimilation via the dihydroxyacetone pathway. J. Biol. Chem. 1997, 272:5544-5554.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5544-5554
    • Norbeck, J.1    Blomberg, A.2
  • 46
    • 0037020260 scopus 로고    scopus 로고
    • Reproducibility of oligonucleotide microarray transcriptome analyses. An interlaboratory comparison using chemostat cultures of Saccharomyces cerevisiae
    • Piper M.D.W., Daran-Lapujade P., Bro C., Regenberg B., Knudsen S., Nielsen J., Pronk J.T. Reproducibility of oligonucleotide microarray transcriptome analyses. An interlaboratory comparison using chemostat cultures of Saccharomyces cerevisiae. J. Biol. Chem. 2002, 277:37001-37008.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37001-37008
    • Piper, M.D.W.1    Daran-Lapujade, P.2    Bro, C.3    Regenberg, B.4    Knudsen, S.5    Nielsen, J.6    Pronk, J.T.7
  • 47
    • 0038514106 scopus 로고    scopus 로고
    • Metabolic flux analysis of xylose metabolism in recombinant Saccharomyces cerevisiae using continuous culture
    • Pitkänen J.P., Aristidou A., Salusjärvi L., Ruohonen L., Penttilä M. Metabolic flux analysis of xylose metabolism in recombinant Saccharomyces cerevisiae using continuous culture. Metab. Eng. 2003, 5:16-31.
    • (2003) Metab. Eng. , vol.5 , pp. 16-31
    • Pitkänen, J.P.1    Aristidou, A.2    Salusjärvi, L.3    Ruohonen, L.4    Penttilä, M.5
  • 48
    • 21344472162 scopus 로고    scopus 로고
    • Xylose chemostat isolates of Saccharomyces cerevisiae show altered metabolite and enzyme levels compared with xylose, glucose, and ethanol metabolism of the original strain
    • Pitkänen J.P., Rintala E., Aristidou A., Ruohonen L., Penttilä M. Xylose chemostat isolates of Saccharomyces cerevisiae show altered metabolite and enzyme levels compared with xylose, glucose, and ethanol metabolism of the original strain. Appl. Microbiol. Biotechnol. 2005, 67:827-837.
    • (2005) Appl. Microbiol. Biotechnol. , vol.67 , pp. 827-837
    • Pitkänen, J.P.1    Rintala, E.2    Aristidou, A.3    Ruohonen, L.4    Penttilä, M.5
  • 49
    • 0032527810 scopus 로고    scopus 로고
    • The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex
    • Platt A., Reece R.J. The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex. EMBO J. 1998, 17:4086-4091.
    • (1998) EMBO J. , vol.17 , pp. 4086-4091
    • Platt, A.1    Reece, R.J.2
  • 50
    • 0037375506 scopus 로고    scopus 로고
    • Production of ethanol from l-arabinose by Saccharomyces cerevisiae containing a fungal l-arabinose pathway
    • Richard P., Verho R., Putkonen M., Londesborough J., Penttilä M. Production of ethanol from l-arabinose by Saccharomyces cerevisiae containing a fungal l-arabinose pathway. FEMS Yeast Res. 2003, 3:185-189.
    • (2003) FEMS Yeast Res. , vol.3 , pp. 185-189
    • Richard, P.1    Verho, R.2    Putkonen, M.3    Londesborough, J.4    Penttilä, M.5
  • 51
    • 70449428931 scopus 로고    scopus 로고
    • Increased expression of the oxidative pentose phosphate pathway and gluconeogenesis in anaerobically growing xylose-utilizing Saccharomyces cerevisiae
    • Runquist D., Hahn-Hägerdal B., Bettiga M. Increased expression of the oxidative pentose phosphate pathway and gluconeogenesis in anaerobically growing xylose-utilizing Saccharomyces cerevisiae. Microb. Cell Fact. 2009, 8.
    • (2009) Microb. Cell Fact. , pp. 8
    • Runquist, D.1    Hahn-Hägerdal, B.2    Bettiga, M.3
  • 53
    • 0027431110 scopus 로고
    • Tkl2, a second transketolase gene of Saccharomyces cerevisiae-cloning, sequence and deletion analysis of the gene
    • Schaaff-Gerstenschläger I., Mannhaupt G., Vetter I., Zimmermann F.K., Feldmann H. Tkl2, a second transketolase gene of Saccharomyces cerevisiae-cloning, sequence and deletion analysis of the gene. Eur. J. Biochem. 1993, 217:487-492.
    • (1993) Eur. J. Biochem. , vol.217 , pp. 487-492
    • Schaaff-Gerstenschläger, I.1    Mannhaupt, G.2    Vetter, I.3    Zimmermann, F.K.4    Feldmann, H.5
  • 54
    • 33748945157 scopus 로고    scopus 로고
    • Production of ethanol from cellulosic biomass hydrolysates using genetically engineered Saccharomyces yeast capable of cofermenting glucose and xylose
    • Sedlak M., Ho N.W. Production of ethanol from cellulosic biomass hydrolysates using genetically engineered Saccharomyces yeast capable of cofermenting glucose and xylose. Appl. Biochem. Biotechnol. 2004, 113-116:403-416.
    • (2004) Appl. Biochem. Biotechnol. , pp. 403-416
    • Sedlak, M.1    Ho, N.W.2
  • 55
    • 0035793151 scopus 로고    scopus 로고
    • Expression of E. coli araBAD operon encoding enzymes for metabolizing l-arabinose in Saccharomyces cerevisiae
    • Sedlak M., Ho N.W.Y. Expression of E. coli araBAD operon encoding enzymes for metabolizing l-arabinose in Saccharomyces cerevisiae. Enzyme Microb. Technol. 2001, 28:16-24.
    • (2001) Enzyme Microb. Technol. , vol.28 , pp. 16-24
    • Sedlak, M.1    Ho, N.W.Y.2
  • 56
    • 64549153538 scopus 로고    scopus 로고
    • Simultaneous quantification of free nucleotides in complex biological samples using ion pair reversed phase liquid chromatography isotope dilution tandem mass spectrometry
    • Seifar R.M., Ras C., Van Dam J.C., van Gulik W.M., Heijnen J.J., van Winden W.A. Simultaneous quantification of free nucleotides in complex biological samples using ion pair reversed phase liquid chromatography isotope dilution tandem mass spectrometry. Anal. Biochem. 2009, 388:213-219.
    • (2009) Anal. Biochem. , vol.388 , pp. 213-219
    • Seifar, R.M.1    Ras, C.2    Van Dam, J.C.3    van Gulik, W.M.4    Heijnen, J.J.5    van Winden, W.A.6
  • 58
    • 2442641770 scopus 로고    scopus 로고
    • Molecular basis for anaerobic growth of Saccharomyces cerevisiae on xylose, investigated by global gene expression and metabolic flux analysis
    • Sonderegger M., Jeppsson M., Hahn-Hägerdal B., Sauer U. Molecular basis for anaerobic growth of Saccharomyces cerevisiae on xylose, investigated by global gene expression and metabolic flux analysis. Appl. Environ. Microbiol. 2004, 70:2307-2317.
    • (2004) Appl. Environ. Microbiol. , vol.70 , pp. 2307-2317
    • Sonderegger, M.1    Jeppsson, M.2    Hahn-Hägerdal, B.3    Sauer, U.4
  • 59
    • 0037394596 scopus 로고    scopus 로고
    • Evolutionary engineering of Saccharomyces cerevisiae for anaerobic growth on xylose
    • Sonderegger M., Sauer U. Evolutionary engineering of Saccharomyces cerevisiae for anaerobic growth on xylose. Appl. Environ. Microbiol. 2003, 69:1990-1998.
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 1990-1998
    • Sonderegger, M.1    Sauer, U.2
  • 60
    • 0024287205 scopus 로고
    • Thermodynamics of isomerization reactions involving sugar phosphates
    • Tewari Y.B., Steckler D.K., Goldberg R.N. Thermodynamics of isomerization reactions involving sugar phosphates. J. Biol. Chem. 1988, 263:3664-3669.
    • (1988) J. Biol. Chem. , vol.263 , pp. 3664-3669
    • Tewari, Y.B.1    Steckler, D.K.2    Goldberg, R.N.3
  • 61
    • 0001985853 scopus 로고
    • Flux determinations in cellular bioreaction networks: applications to lysine fermentations. In: S.K. Skidar, M. Bier, P. Todd (Eds.), Frontiers in Bioprocess. CRC Press, Boca Raton, FL
    • Vallino, J.J., Stephanopoulos, G., 1990. Flux determinations in cellular bioreaction networks: applications to lysine fermentations. In: S.K. Skidar, M. Bier, P. Todd (Eds.), Frontiers in Bioprocess. CRC Press, Boca Raton, FL, pp. 205-219.
    • (1990) , pp. 205-219
    • Vallino, J.J.1    Stephanopoulos, G.2
  • 62
    • 0037024247 scopus 로고    scopus 로고
    • Analysis of glycolytic metabolites in Saccharomyces cerevisiae using anion exchange chromatography and electrospray ionization with tandem mass spectrometric detection
    • Van Dam J.C., Eman M.R., Frank J., Lange H.C., van Dedem G.W.K., Heijnen J.J. Analysis of glycolytic metabolites in Saccharomyces cerevisiae using anion exchange chromatography and electrospray ionization with tandem mass spectrometric detection. Anal. Chim. Acta 2002, 460:209-218.
    • (2002) Anal. Chim. Acta , vol.460 , pp. 209-218
    • Van Dam, J.C.1    Eman, M.R.2    Frank, J.3    Lange, H.C.4    van Dedem, G.W.K.5    Heijnen, J.J.6
  • 63
    • 0022507007 scopus 로고
    • Redox balances in the metabolism of sugars by yeasts
    • van Dijken J.P., Scheffers W.A. Redox balances in the metabolism of sugars by yeasts. FEMS Microbiol. Rev. 1986, 32:199-224.
    • (1986) FEMS Microbiol. Rev. , vol.32 , pp. 199-224
    • van Dijken, J.P.1    Scheffers, W.A.2
  • 64
    • 0028973161 scopus 로고
    • A metabolic network stoichiometry analysis of microbial growth and product formation
    • van Gulik W.M., Heijnen J.J. A metabolic network stoichiometry analysis of microbial growth and product formation. Biotechnol. Bioeng. 1995, 48:681-698.
    • (1995) Biotechnol. Bioeng. , vol.48 , pp. 681-698
    • van Gulik, W.M.1    Heijnen, J.J.2
  • 66
    • 0024257862 scopus 로고
    • Metabolic responses of Saccharomyces cerevisiae CBS 8066 and Candida utilis CBS 621 upon transition from glucose limitation to glucose excess
    • van Urk H., Mak P.R., Scheffers W.A., van Dijken J.P. Metabolic responses of Saccharomyces cerevisiae CBS 8066 and Candida utilis CBS 621 upon transition from glucose limitation to glucose excess. Yeast 1988, 4:283-291.
    • (1988) Yeast , vol.4 , pp. 283-291
    • van Urk, H.1    Mak, P.R.2    Scheffers, W.A.3    van Dijken, J.P.4
  • 69
    • 0014619162 scopus 로고
    • Disequilibrium in triose phosphate isomerase system in rat liver
    • Veech R.L., Raijman L., Dalziel K., Krebs H.A. Disequilibrium in triose phosphate isomerase system in rat liver. Biochem. J. 1969, 115:837-842.
    • (1969) Biochem. J. , vol.115 , pp. 837-842
    • Veech, R.L.1    Raijman, L.2    Dalziel, K.3    Krebs, H.A.4
  • 70
    • 0025318231 scopus 로고
    • Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures
    • Verduyn C., Postma E., Scheffers W.A., van Dijken J.P. Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. J. Gen. Microbiol. 1990, 136:395-403.
    • (1990) J. Gen. Microbiol. , vol.136 , pp. 395-403
    • Verduyn, C.1    Postma, E.2    Scheffers, W.A.3    van Dijken, J.P.4
  • 71
    • 0026710123 scopus 로고
    • Effect of benzoic acid on metabolic fluxes in yeasts: a continuous-culture study on the regulation of respiration and alcoholic fermentation
    • Verduyn C., Postma E., Scheffers W.A., van Dijken J.P. Effect of benzoic acid on metabolic fluxes in yeasts: a continuous-culture study on the regulation of respiration and alcoholic fermentation. Yeast 1992, 8:501-517.
    • (1992) Yeast , vol.8 , pp. 501-517
    • Verduyn, C.1    Postma, E.2    Scheffers, W.A.3    van Dijken, J.P.4
  • 72
    • 0347297600 scopus 로고    scopus 로고
    • Molecular analysis of a Saccharomyces cerevisiae mutant with improved ability to utilize xylose shows enhanced expression of proteins involved in transport, initial xylose metabolism, and the pentose phosphate pathway
    • Wahlbom C.F., Cordero Otero R.R., van Zyl W.H., Hahn-Hägerdal B., Jonsson L.J. Molecular analysis of a Saccharomyces cerevisiae mutant with improved ability to utilize xylose shows enhanced expression of proteins involved in transport, initial xylose metabolism, and the pentose phosphate pathway. Appl. Environ. Microbiol. 2003, 69:740-746.
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 740-746
    • Wahlbom, C.F.1    Cordero Otero, R.R.2    van Zyl, W.H.3    Hahn-Hägerdal, B.4    Jonsson, L.J.5
  • 73
    • 0035809032 scopus 로고    scopus 로고
    • Intracellular fluxes in a recombinant xylose-utilizing Saccharomyces cerevisiae cultivated anaerobically at different dilution rates and feed concentrations
    • Wahlbom C.F., Eliasson A., Hahn-Hägerdal B. Intracellular fluxes in a recombinant xylose-utilizing Saccharomyces cerevisiae cultivated anaerobically at different dilution rates and feed concentrations. Biotechnol. Bioeng. 2001, 72:289-296.
    • (2001) Biotechnol. Bioeng. , vol.72 , pp. 289-296
    • Wahlbom, C.F.1    Eliasson, A.2    Hahn-Hägerdal, B.3
  • 74
    • 0028790841 scopus 로고
    • SOK2 may regulate cyclic AMP-dependent protein kinase-stimulated growth and pseudohyphal development by repressing transcription
    • Ward M.P., Gimeno C.J., Fink G.R., Garrett S. SOK2 may regulate cyclic AMP-dependent protein kinase-stimulated growth and pseudohyphal development by repressing transcription. Mol. Cell Biol. 1995, 15:6854-6863.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 6854-6863
    • Ward, M.P.1    Gimeno, C.J.2    Fink, G.R.3    Garrett, S.4
  • 75
    • 33845958976 scopus 로고    scopus 로고
    • A systems biology approach to study glucose repression in the yeast Saccharomyces cerevisiae
    • Westergaard S.L., Oliveira A.P., Bro C., Olsson L., Nielsen J. A systems biology approach to study glucose repression in the yeast Saccharomyces cerevisiae. Biotechnol. Bioeng. 2007, 96:134-145.
    • (2007) Biotechnol. Bioeng. , vol.96 , pp. 134-145
    • Westergaard, S.L.1    Oliveira, A.P.2    Bro, C.3    Olsson, L.4    Nielsen, J.5
  • 76
    • 0028314909 scopus 로고
    • Effects of oxygen limitation on sugar metabolism in yeasts-a continuous-culture study of the Kluyver effect
    • Weusthuis R.A., Visser W., Pronk J.T., Scheffers W.A., van Dijken J.P. Effects of oxygen limitation on sugar metabolism in yeasts-a continuous-culture study of the Kluyver effect. Microbiology 1994, 140:703-715.
    • (1994) Microbiology , vol.140 , pp. 703-715
    • Weusthuis, R.A.1    Visser, W.2    Pronk, J.T.3    Scheffers, W.A.4    van Dijken, J.P.5
  • 79
    • 0036036461 scopus 로고    scopus 로고
    • Fermentation performance and intracellular metabolite patterns in laboratory and industrial xylose-fermenting Saccharomyces cerevisiae
    • Zaldivar J., Borges A., Johansson B., Smits H.P., Villas-Boas S.G., Nielsen J., Olsson L. Fermentation performance and intracellular metabolite patterns in laboratory and industrial xylose-fermenting Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 2002, 59:436-442.
    • (2002) Appl. Microbiol. Biotechnol. , vol.59 , pp. 436-442
    • Zaldivar, J.1    Borges, A.2    Johansson, B.3    Smits, H.P.4    Villas-Boas, S.G.5    Nielsen, J.6    Olsson, L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.