Angiotensin-converting enzyme gene polymorphism and its association with essential hypertension in a Tibetan population

Hypertension Research

Volumn 25, Issue 3, 2002, Pages 481-485

  Gesang, Luobu ^a   Liu, Guozhang ^a   Cen, Weijun ^a   Qiu, Changchun ^a   Zhuoma, Ciren ^a   Zhuang, Lanping ^a   Ren, Dan ^a   Pincuo, Zhaxi ^a   Chan, Yong ^a  

^a People's Hospital of Tibet Autonomous Region   (China)

Author keywords

Angiotensin; Gene; Hypertension

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; ARTICLE; BLOOD PRESSURE; CASE CONTROL STUDY; CHINA; COMPLICATION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ESSENTIAL HYPERTENSION; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; POLYMERASE CHAIN REACTION; RACE DIFFERENCE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM; URBAN POPULATION; AGED; CROSS-SECTIONAL STUDY; ENZYMOLOGY; GENETICS; GENOTYPE; HYPERTENSION; MIDDLE AGED; SEX DIFFERENCE;

ADULT; AGED; CROSS-SECTIONAL STUDIES; FEMALE; GENOTYPE; HUMAN; HYPERTENSION; MALE; MIDDLE AGE; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM (GENETICS); SEX FACTORS; SUPPORT, NON-U.S. GOV'T; TIBET; HUMANS; MIDDLE AGED; POLYMORPHISM, GENETIC;

EID: 0035991479     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.25.481     Document Type: Article

References (17)

1. An insertion/deletion polymorphism in the angiotensin-converting enzyme gene account for half of the variance in serum ACE levels
2. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study
3. Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males
4. Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in Japanese men
5. Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin converting enzyme gene controls plasma ACE levels
6. Mistyping of ACE heterozygotes
7. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
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