Polyketide β-branching in bryostatin biosynthesis: Identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase

Chemistry and Biology

Volumn 17, Issue 10, 2010, Pages 1092-1100

  Buchholz, Tonia J ^a   Rath, Christopher M ^a   Lopanik, Nicole B ^a,c   Gardner, Noah P ^a   Håkansson, Kristina ^a   Sherman, David H ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; BRYOSTATIN; BRYOSTATIN 1; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE;

AMINO ACID SEQUENCE; ARTICLE; BIOSYNTHESIS; CHEMISTRY; CLASSIFICATION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SURFACE PLASMON RESONANCE;

ACYL CARRIER PROTEIN; AMINO ACID SEQUENCE; BRYOSTATINS; CATALYTIC DOMAIN; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; SURFACE PLASMON RESONANCE;

BACTERIA (MICROORGANISMS);

EID: 78049389074     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2010.08.008     Document Type: Article

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