Polyketide-chain branching by an enzymatic Michael addition

Angewandte Chemie - International Edition

Volumn 48, Issue 27, 2009, Pages 5001-5004

  Kusebauch, Björn ^a   Busch, Benjamin ^a   Scherlach, Kirstin ^a   Roth, Martin ^a   Hertweck, Christian ^a,b  

^a HANS KNÖLL INSTITUTE   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Conjugate addition; Macrolides; Natural products; Polyketides; Rhizoxin

Indexed keywords

CONJUGATE ADDITION; MACROLIDES; NATURAL PRODUCTS; POLYKETIDES; RHIZOXIN;

ADDITION REACTIONS; BIOCHEMISTRY;

GENETIC ENGINEERING;

ANTINEOPLASTIC AGENT; MACROLIDE; POLYKETIDE SYNTHASE; RHIZOXIN;

BIOCATALYSIS; BURKHOLDERIA; CHEMISTRY; ENZYMOLOGY; GENE INACTIVATION; GENETICS; METABOLISM; MULTIGENE FAMILY; PROTEIN TERTIARY STRUCTURE;

ANTINEOPLASTIC AGENTS; BIOCATALYSIS; BURKHOLDERIA; GENE KNOCKOUT TECHNIQUES; MACROLIDES; MULTIGENE FAMILY; POLYKETIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY;

EID: 70349909730     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200900277     Document Type: Article

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