Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula: Insights into a decarboxylase involved in polyketide chain β-branching

Journal of Biological Chemistry

Volumn 282, Issue 49, 2007, Pages 35954-35963

  Geders, Todd W ^a,b   Gu, Liangcai ^c   Mowers, Jonathan C ^a   Liu, Haichuan ^c   Gerwick, William H ^d   Håkansson, Kristina ^c   Sherman, David H ^c   Smith, Janet L ^a,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b PURDUE UNIVERSITY   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CARBOXYLATION; CATALYSIS; CROSSLINKING; CRYSTAL STRUCTURE; ENZYMES;

CYCLOPROPANE RING; POLAR SIDE CHAINS; SUPERFAMILY MEMBER;

ALGAE;

3 METHYLGLUTACONIC ACID; ALANINE; CARBOXYLIC ACID; CARBOXYLYASE; COENZYME A; ENOYL COENZYME A HYDRATASE; GLYCINE; HISTIDINE; LYSINE; POLYKETIDE; PROTON; TYROSINE; BACTERIAL PROTEIN; CURACIN A; CYCLOPROPANE DERIVATIVE; MACROLIDE; THIAZOLE DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOCHEMISTRY; CATALYSIS; CRYSTAL STRUCTURE; DECARBOXYLATION; LYNGBYA MAJUSCULA; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; AMINO ACID SUBSTITUTION; BINDING SITE; CHEMISTRY; CYANOBACTERIUM; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; METABOLISM; MISSENSE MUTATION; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

LYNGBYA MAJUSCULA;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BINDING SITES; CARBOXY-LYASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYANOBACTERIA; CYCLOPROPANES; ENOYL-COA HYDRATASE; MACROLIDES; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; SUBSTRATE SPECIFICITY; THIAZOLES;

EID: 37248999755     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M703921200     Document Type: Article

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