-
1
-
-
33748947179
-
The role of mitochondrial respiration in physiological and evolutionary adaptation
-
Das J (2006) The role of mitochondrial respiration in physiological and evolutionary adaptation. Bioessays 28: 890-901.
-
(2006)
Bioessays
, vol.28
, pp. 890-901
-
-
Das, J.1
-
2
-
-
0034611678
-
Towards a molecular understanding of adaptive thermogenesis
-
Lowell BB, Spiegelman BM (2000) Towards a molecular understanding of adaptive thermogenesis. Nature 404: 652-660.
-
(2000)
Nature
, vol.404
, pp. 652-660
-
-
Lowell, B.B.1
Spiegelman, B.M.2
-
3
-
-
85047700144
-
Relationship between juvenile obesity, dietary energy and fat intake and physical activity
-
Gillis LJ, Kennedy LC, Gillis AM, Bar-Or O (2002) Relationship between juvenile obesity, dietary energy and fat intake and physical activity. International J Obesity 26: 458-463.
-
(2002)
International J Obesity
, vol.26
, pp. 458-463
-
-
Gillis, L.J.1
Kennedy, L.C.2
Gillis, A.M.3
Bar-Or, O.4
-
4
-
-
67649841598
-
Fat storage and the biology of energy expenditure
-
Redinger RN (2009) Fat storage and the biology of energy expenditure. Transl Res 154: 52-60.
-
(2009)
Transl Res
, vol.154
, pp. 52-60
-
-
Redinger, R.N.1
-
5
-
-
0018785949
-
Endothermy and activity in vertebrates
-
Bennett AF, Ruben JA (1979) Endothermy and activity in vertebrates. Science 206: 649-654.
-
(1979)
Science
, vol.206
, pp. 649-654
-
-
Bennett, A.F.1
Ruben, J.A.2
-
6
-
-
71249100778
-
Lack of adequate appreciation of physical exercise's complexities can pre-emp appropriate design and interpretation in scientific discovery
-
Booth FW, Laye MJ (2009) Lack of adequate appreciation of physical exercise's complexities can pre-emp appropriate design and interpretation in scientific discovery. J Physiol 587: 5527-5540.
-
(2009)
J Physiol
, vol.587
, pp. 5527-5540
-
-
Booth, F.W.1
Laye, M.J.2
-
7
-
-
58049195487
-
Linking performance and chronic disease risk: Indices of physical performance are surrogates for health
-
Booth FW, Roberts CK (2008) Linking performance and chronic disease risk: indices of physical performance are surrogates for health. Brit J Sport Med 42: 950-952.
-
(2008)
Brit J Sport Med
, vol.42
, pp. 950-952
-
-
Booth, F.W.1
Roberts, C.K.2
-
8
-
-
47949104798
-
The role of exercise and PGC1 alpha in inflammation and chronic disease
-
Handschin C, Spiegelman BM (2008) The role of exercise and PGC1 alpha in inflammation and chronic disease. Nature 454: 463-469.
-
(2008)
Nature
, vol.454
, pp. 463-469
-
-
Handschin, C.1
Spiegelman, B.M.2
-
9
-
-
61849086539
-
A changing paradigm for prevention of cardiovascular disease: Emergence of the metabolic syndrome as a multiplex risk factor
-
Grundy SM (2008) A changing paradigm for prevention of cardiovascular disease: emergence of the metabolic syndrome as a multiplex risk factor. Eur Heart J Suppl 10: B16-B23.
-
(2008)
Eur Heart J Suppl
, vol.10
-
-
Grundy, S.M.1
-
10
-
-
45549108083
-
Reduced physical activity and risk of chronic disease: The biology behind the consequences
-
Booth FW, Laye MJ, Lees SJ, Rector RS, Thyfault JP (2008) Reduced physical activity and risk of chronic disease: the biology behind the consequences. Eur J Appl Physiol 102: 381-390.
-
(2008)
Eur J Appl Physiol
, vol.102
, pp. 381-390
-
-
Booth, F.W.1
Laye, M.J.2
Lees, S.J.3
Rector, R.S.4
Thyfault, J.P.5
-
11
-
-
68149137621
-
eNOS, metabolic syndrome and cardiovascular disease
-
Huang PL (2009) eNOS, metabolic syndrome and cardiovascular disease. Trends Endocrin Metabol 20: 295-302.
-
(2009)
Trends Endocrin Metabol
, vol.20
, pp. 295-302
-
-
Huang, P.L.1
-
12
-
-
0036712032
-
Exercise and gene expression: Physiological regulation of the human genome through physical activity
-
Booth FW, Chakravarthy MV, Spangenburg EE (2002) Exercise and gene expression: physiological regulation of the human genome through physical activity. J Physiol 543: 399-411.
-
(2002)
J Physiol
, vol.543
, pp. 399-411
-
-
Booth, F.W.1
Chakravarthy, M.V.2
Spangenburg, E.E.3
-
13
-
-
48449094498
-
AMPK and PPAR delta agonists are exercise mimetics
-
Narkar VA, Downes M, Yu RT, Embler E, Wang YX, et al. (2008) AMPK and PPAR delta agonists are exercise mimetics. Cell 134: 405-415.
-
(2008)
Cell
, vol.134
, pp. 405-415
-
-
Narkar, V.A.1
Downes, M.2
Yu, R.T.3
Embler, E.4
Wang, Y.X.5
-
14
-
-
0347660639
-
Controlling muscle mitochondrial content
-
Moyes CD (2003) Controlling muscle mitochondrial content. J Exp Biol 206: 4385-4391.
-
(2003)
J Exp Biol
, vol.206
, pp. 4385-4391
-
-
Moyes, C.D.1
-
15
-
-
72649089588
-
Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity
-
Hoehn KL, Turner N, Swarbrick MM, Wilks D, Preston E, et al. (2010) Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. Cell Metabol 11: 70-76.
-
(2010)
Cell Metabol
, vol.11
, pp. 70-76
-
-
Hoehn, K.L.1
Turner, N.2
Swarbrick, M.M.3
Wilks, D.4
Preston, E.5
-
16
-
-
0019405046
-
Influence of mild cold on 24 h energy expenditure, resting metabolism and diet-induced thermogenesis
-
Dauncey MJ (1981) Influence of mild cold on 24 h energy expenditure, resting metabolism and diet-induced thermogenesis. Brit J Nutr 45: 257-267.
-
(1981)
Brit J Nutr
, vol.45
, pp. 257-267
-
-
Dauncey, M.J.1
-
17
-
-
42049114034
-
Transcriptional paradigms in mammalian mitochondrial biogenesis and function
-
Scarpulla RC (2008) Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol Rev 88: 611-638.
-
(2008)
Physiol Rev
, vol.88
, pp. 611-638
-
-
Scarpulla, R.C.1
-
18
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu ZD, Puigserver P, Andersson U, Zhang CY, Adelmant G, et al. (1999) Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98: 115-124.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.D.1
Puigserver, P.2
Andersson, U.3
Zhang, C.Y.4
Adelmant, G.5
-
19
-
-
0032549811
-
A coldinducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M, et al. (1998) A coldinducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92: 829-839.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
-
20
-
-
0037326196
-
Peroxisome proliferator-activated receptorgamma coactivator 1 alpha (PGC-1 alpha): Transcriptional coactivator and metabolic regulator
-
Puigserver P, Spiegelman BM (2003) Peroxisome proliferator-activated receptorgamma coactivator 1 alpha (PGC-1 alpha): Transcriptional coactivator and metabolic regulator. Endocr Rev 24: 78-90.
-
(2003)
Endocr Rev
, vol.24
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
21
-
-
0036903174
-
Adaptations of skeletal muscle to exercise: Rapid increase in the transcriptional coactivator PGC-1
-
Baar K, Wende AR, Jones TE, Marison M, Nolte LA, et al. (2002) Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. Faseb J 16: 1879-1886.
-
(2002)
Faseb J
, vol.16
, pp. 1879-1886
-
-
Baar, K.1
Wende, A.R.2
Jones, T.E.3
Marison, M.4
Nolte, L.A.5
-
22
-
-
0642303113
-
Peroxisome proliferator-activated receptor delta controls muscle development and oxydative capability
-
Luquet S, Lopez-Soriano J, Holst D, Fredenrich A, Melki J, et al. (2003) Peroxisome proliferator-activated receptor delta controls muscle development and oxydative capability. Faseb J 17: 2299-2301.
-
(2003)
Faseb J
, vol.17
, pp. 2299-2301
-
-
Luquet, S.1
Lopez-Soriano, J.2
Holst, D.3
Fredenrich, A.4
Melki, J.5
-
23
-
-
0037453718
-
Peroxisomeproliferator- activated receptor delta activates fat metabolism to prevent obesity
-
Wang YX, Lee CH, Tiep S, Yu RT, Ham JY, et al. (2003) Peroxisomeproliferator- activated receptor delta activates fat metabolism to prevent obesity. Cell 113: 159-170.
-
(2003)
Cell
, vol.113
, pp. 159-170
-
-
Wang, Y.X.1
Lee, C.H.2
Tiep, S.3
Yu, R.T.4
Ham, J.Y.5
-
24
-
-
8844276054
-
Regulation of muscle fiber type and running endurance by PPAR delta
-
Wang YX, Zhang CL, Yu RT, Cho HK, Nelson MC, et al. (2004) Regulation of muscle fiber type and running endurance by PPAR delta. PLoS Biol 2: 1532-1539.
-
(2004)
PLoS Biol
, vol.2
, pp. 1532-1539
-
-
Wang, Y.X.1
Zhang, C.L.2
Yu, R.T.3
Cho, H.K.4
Nelson, M.C.5
-
25
-
-
0035283207
-
UCP1: The only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency
-
Nedergaard J, Golozoubova V, Matthias A, Asadi A, Jacobsson A, et al. (2001) UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency. Biochim Et Biophys Acta-Bioenergetics 1504: 82-106.
-
(2001)
Biochim Et Biophys Acta-Bioenergetics
, vol.1504
, pp. 82-106
-
-
Nedergaard, J.1
Golozoubova, V.2
Matthias, A.3
Asadi, A.4
Jacobsson, A.5
-
26
-
-
0037251008
-
Cold-induced recruitment of brown adipose tissue thermogenesis
-
Klingenspor M (2003) Cold-induced recruitment of brown adipose tissue thermogenesis. Exp Physiol 88: 141-148.
-
(2003)
Exp Physiol
, vol.88
, pp. 141-148
-
-
Klingenspor, M.1
-
27
-
-
0347989317
-
Brown adipose tissue: Function and physiological significance
-
Cannon B, Nedergaard J (2004) Brown adipose tissue: Function and physiological significance. Physiol Rev 84: 277-359.
-
(2004)
Physiol Rev
, vol.84
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
28
-
-
33745627066
-
Transverse aortic constriction leads to accelarated heart failure in mice lacking PPAR-c coactivator 1a
-
Arany Z, Novlkov M, Chin S, Rosenzweig A, Spiegelman BM (2006) Transverse aortic constriction leads to accelarated heart failure in mice lacking PPAR-c coactivator 1a. Proc Natl Acad Sci USA 103: 10086-10091.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10086-10091
-
-
Arany, Z.1
Novlkov, M.2
Chin, S.3
Rosenzweig, A.4
Spiegelman, B.M.5
-
29
-
-
75849155745
-
The transcriptional coactivator PGC-1a mediates exercise-induced angiogenesis in skeletal muscle
-
Chinsomboon J, Ruas J, Gupta RK, Thom R, Shoag J, et al. (2009) The transcriptional coactivator PGC-1a mediates exercise-induced angiogenesis in skeletal muscle. Proc Natl Acad Sci USA 106: 21401-21406.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21401-21406
-
-
Chinsomboon, J.1
Ruas, J.2
Gupta, R.K.3
Thom, R.4
Shoag, J.5
-
30
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1a
-
Jäger S, Handschirm C, St.-Pierre J, Spiegelman BM (2007) AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1a. Proc Natl Acad Sci USA 104: 12017-12022.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12017-12022
-
-
Jäger, S.1
Handschirm, C.2
St.-Pierre, J.3
Spiegelman, B.M.4
-
31
-
-
34250740323
-
Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1a transcription coactivator
-
Li X, Monks B, Ge Q, Birnbaum MJ (2007) Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1a transcription coactivator. Nature 447: 1012-1017.
-
(2007)
Nature
, vol.447
, pp. 1012-1017
-
-
Li, X.1
Monks, B.2
Ge, Q.3
Birnbaum, M.J.4
-
32
-
-
0037102256
-
Transcription coactivator PGC-1a drives the formation of slow-twitch muscle fibres
-
Lin J, Wu H, Tarr PT, Zhang C-Y, Wu Z, et al. (2001) Transcription coactivator PGC-1a drives the formation of slow-twitch muscle fibres. Nature 418: 797-801.
-
(2001)
Nature
, vol.418
, pp. 797-801
-
-
Lin, J.1
Wu, H.2
Tarr, P.T.3
Zhang, C.-Y.4
Wu, Z.5
-
33
-
-
58149394230
-
Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals
-
Holloway GP, Bonen A, Spriet LL (2009) Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals. American J Clin Nutr 89: 455S-462S.
-
(2009)
American J Clin Nutr
, vol.89
-
-
Holloway, G.P.1
Bonen, A.2
Spriet, L.L.3
-
34
-
-
0037008157
-
BAR signaling required for diet-induced thermogenesis and obesity resistance
-
Bachman ES, Dhillon H, Zhang C-Y, Cinti S, Bianco AC (2002) bAR signaling required for diet-induced thermogenesis and obesity resistance. Nature 297: 843-845.
-
(2002)
Nature
, vol.297
, pp. 843-845
-
-
Bachman, E.S.1
Dhillon, H.2
Zhang, C.-Y.3
Cinti, S.4
Bianco, A.C.5
-
35
-
-
77949328118
-
Thermogenesis challenges the adipostat hypothesis for body-weight control
-
Cannon B, Nedergaard J (2009) Thermogenesis challenges the adipostat hypothesis for body-weight control. Proc Nutr Soc 68: 401-407.
-
(2009)
Proc Nutr Soc
, vol.68
, pp. 401-407
-
-
Cannon, B.1
Nedergaard, J.2
-
36
-
-
77958535632
-
Lower body temperatures are advantageous for a small mammal (bush rat, Rattus fuscipes) experiencing chronic cold
-
in press
-
Glanville EJ, Seebacher F (2010) Lower body temperatures are advantageous for a small mammal (bush rat, Rattus fuscipes) experiencing chronic cold. J Mammal, in press.
-
(2010)
J Mammal
-
-
Glanville, E.J.1
Seebacher, F.2
-
37
-
-
74449091178
-
Plasticity in body temperature and metabolic capacity sustains winter activity in a small endotherm (Rattus fuscipes)
-
Glanville EJ, Seebacher F (2010) Plasticity in body temperature and metabolic capacity sustains winter activity in a small endotherm (Rattus fuscipes). Comp Biochem Physiol A 155: 383-391.
-
(2010)
Comp Biochem Physiol A
, vol.155
, pp. 383-391
-
-
Glanville, E.J.1
Seebacher, F.2
-
38
-
-
33744910824
-
Contribution of thermal and nonthermal factors to the regulation of body temperature in humans
-
Mekjavic IB, Eiken O (2006) Contribution of thermal and nonthermal factors to the regulation of body temperature in humans. J Appl Physiol 100: 2065-2072.
-
(2006)
J Appl Physiol
, vol.100
, pp. 2065-2072
-
-
Mekjavic, I.B.1
Eiken, O.2
-
39
-
-
65549096847
-
Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: Insulin resistance, friend or foe?
-
Nunn AVW, Bell JD, Guy GW (2009) Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe? Nutr Metabol 6.
-
(2009)
Nutr Metabol
, pp. 6
-
-
Nunn, A.V.W.1
Bell, J.D.2
Guy, G.W.3
-
41
-
-
9144262378
-
Cardiomyocyterestricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
-
Cheng L, Ding G, Qin Q, Huang Y, Lewis W, et al. (2004) Cardiomyocyterestricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nature Med 10: 1245-1250.
-
(2004)
Nature Med
, vol.10
, pp. 1245-1250
-
-
Cheng, L.1
Ding, G.2
Qin, Q.3
Huang, Y.4
Lewis, W.5
-
42
-
-
63649121321
-
Regulation by exercise of skeletal muscle content of mitochondria and GLUT4
-
Holloszy JO (2008) Regulation by exercise of skeletal muscle content of mitochondria and GLUT4. J Physiol Pharmacol 59: 5-18.
-
(2008)
J Physiol Pharmacol
, vol.59
, pp. 5-18
-
-
Holloszy, J.O.1
-
43
-
-
67849089176
-
BAT: A new target for human obesity?
-
Fruhbeck G, Becerril S, Sainz N, Garrastachu P, Garcia-Velloso MJ (2009) BAT: a new target for human obesity? Trends Pharmacol Sci 30: 387-396.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 387-396
-
-
Fruhbeck, G.1
Becerril, S.2
Sainz, N.3
Garrastachu, P.4
Garcia-Velloso, M.J.5
-
44
-
-
0028865142
-
Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity
-
Kopecky J, Clarke G, Enerback S, Spiegelman B, Kozak LP (1995) Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity. J Clin Invest 96: 2914-2923.
-
(1995)
J Clin Invest
, vol.96
, pp. 2914-2923
-
-
Kopecky, J.1
Clarke, G.2
Enerback, S.3
Spiegelman, B.4
Kozak, L.P.5
-
45
-
-
58149529580
-
UCP1: Its involvement and utility in obesity
-
Kozak LP, Anunciado-Koza R (2008) UCP1: its involvement and utility in obesity. Int J Obesity 32: S32-S38.
-
(2008)
Int J Obesity
, vol.32
-
-
Kozak, L.P.1
Anunciado-Koza, R.2
-
46
-
-
58749091645
-
UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
-
Feldman HM, Golozoubova V, Cannon B, Nedergaard J (2009) UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab 9: 203-209.
-
(2009)
Cell Metab
, vol.9
, pp. 203-209
-
-
Feldman, H.M.1
Golozoubova, V.2
Cannon, B.3
Nedergaard, J.4
-
47
-
-
64349095231
-
Cold-activated brown adipose tissue in healthy men
-
Lichtenbelt WDV, Vanhommerig JW, Smulders NM, Drossaerts J, Kemerink GJ (2009) Cold-activated brown adipose tissue in healthy men. New Engl J Med 360: 1500-1508.
-
(2009)
New Engl J Med
, vol.360
, pp. 1500-1508
-
-
Lichtenbelt, W.D.V.1
Vanhommerig, J.W.2
Smulders, N.M.3
Drossaerts, J.4
Kemerink, G.J.5
-
48
-
-
77950221998
-
Human brown adipose tissue
-
Enerbäck S (2010) Human brown adipose tissue. Cell Metab 11: 248-252.
-
(2010)
Cell Metab
, vol.11
, pp. 248-252
-
-
Enerbäck, S.1
-
49
-
-
34249730751
-
Transient receptor potential ion channels control thermoregulatory behaviour in reptiles
-
Seebacher F, Murray, SA (2007) Transient receptor potential ion channels control thermoregulatory behaviour in reptiles. PLoS One 2: e281.
-
(2007)
PLoS One
, vol.2
-
-
Seebacher, F.1
Murray, S.A.2
-
50
-
-
17344392308
-
A new mathematical model for the relative quantification in real-time RT-PCR
-
Pfaffl MW (2001) A new mathematical model for the relative quantification in real-time RT-PCR. Nucl Acid Res 29: 2002-2007.
-
(2001)
Nucl Acid Res
, vol.29
, pp. 2002-2007
-
-
Pfaffl, M.W.1
-
51
-
-
0037386379
-
Seasonal acclimatisation of muscle metabolic enzymes in a reptile (Alligator mississippiensis)
-
Seebacher F, Guderley H, Elsey RM, Trosclair PL (2003) Seasonal acclimatisation of muscle metabolic enzymes in a reptile (Alligator mississippiensis). J Exp Biol 206: 1193-1200.
-
(2003)
J Exp Biol
, vol.206
, pp. 1193-1200
-
-
Seebacher, F.1
Guderley, H.2
Elsey, R.M.3
Trosclair, P.L.4
-
52
-
-
0034779544
-
Design, calibration and calculation for flow-through respirometry systems
-
Withers PC (2001) Design, calibration and calculation for flow-through respirometry systems. Aust J Zool 49: 445-461.
-
(2001)
Aust J Zool
, vol.49
, pp. 445-461
-
-
Withers, P.C.1
-
53
-
-
0001495141
-
The respiratory metabolism and swimming performance of young sockeye salmon
-
Brett JR (1964) The respiratory metabolism and swimming performance of young sockeye salmon. J Fish Res 21: 1183-1226.
-
(1964)
J Fish Res
, vol.21
, pp. 1183-1226
-
-
Brett, J.R.1
-
54
-
-
10344249454
-
Voluntary running in deer mice: Speed, distance, energy costs and temperature effects
-
Chappell MA, Garland T, Rezende EL, Gomes FR (2004) Voluntary running in deer mice: speed, distance, energy costs and temperature effects. J Exp Biology 207: 3839-3854.
-
(2004)
J Exp Biology
, vol.207
, pp. 3839-3854
-
-
Chappell, M.A.1
Garland, T.2
Rezende, E.L.3
Gomes, F.R.4
|