Participation of nuclear factor (erythroid 2-related), factor 2 in ameliorating lithocholic acid-induced cholestatic liver injury in mice

British Journal of Pharmacology

Volumn 161, Issue 5, 2010, Pages 1111-1121

  Tan, K P ^a   Wood, G A ^b   Yang, M ^a   Ito, S ^a  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

ATP binding cassette transporters; Cholestasis; Glutathione; Glutathione S transferases; Haeme oxygenase 1; Lipid peroxidation; Lithocholic acid; Liver injury; Nrf2; Oxidative stress; Thioredoxin reductase 1

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; BIOLOGICAL MARKER; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE TRANSFERASE; HEME OXYGENASE 1; LITHOCHOLIC ACID; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; THIOREDOXIN REDUCTASE 1; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT; CELL PROTECTION; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; GENE INDUCTION; GENE TARGETING; INTRAHEPATIC CHOLESTASIS; LIPID PEROXIDATION; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; LIVER TOXICITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE;

ANIMALS; BILE DUCTS; BIOLOGICAL MARKERS; CHOLESTASIS, INTRAHEPATIC; LIPID PEROXIDATION; LITHOCHOLIC ACID; LIVER; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; NECROSIS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; SEVERITY OF ILLNESS INDEX;

EID: 77958517394     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00953.x     Document Type: Article

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