Nuclear factor-E2-related factor 2 expression in liver is critical for induction of NAD(P)H:quinone oxidoreductase 1 during cholestasis

Cell Stress and Chaperones

Volumn 11, Issue 4, 2006, Pages 356-363

  Aleksunes, Lauren M ^a   Slitt, Angela L ^b   Maher, Jonathan M ^b   Dieter, Matthew Z ^b   Knight, Tamara R ^b   Goedken, Michael ^a   Cherrington, Nathan J ^c   Chan, Jefferson Y ^d   Klaassen, Curtis D ^b   Manautou, José E ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; MESSENGER RNA; QUINONE OXIDOREDUCTASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ALANINE AMINOTRANSFERASE; BILE ACID; GLUTATHIONE TRANSFERASE; HEME OXYGENASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NQO1 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; CHOLESTASIS; CONTROLLED STUDY; ENZYME ACTIVITY; FOLLOW UP; GENE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE; ANIMAL; BILE DUCT; C57BL MOUSE; ENZYMOLOGY; GENETICS; LIVER; METABOLISM; PATHOLOGY;

MUS;

ALANINE TRANSAMINASE; ANIMALS; BILE ACIDS AND SALTS; BILE DUCTS; CHOLESTASIS; GLUTATHIONE TRANSFERASE; HEME OXYGENASE-1; LIVER; MALE; MICE; MICE, INBRED C57BL; NADP; NADPH DEHYDROGENASE; NF-E2-RELATED FACTOR 2; RNA, MESSENGER;

EID: 33947588378     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1379/CSC-217.1     Document Type: Article

References (23)

1. Aboutwerat A, Pemberton PW, Smith A, Burrows PC, McMahon F, Jain SK, Warnes TW. 2003. Oxidant stress is a significant feature of primary biliary cirrhosis. Biochim Biophys Acta 1637: 142-150.
2. Aleksunes LM, Goedken MJ, Manautou JE. 2006. Up-regulation of NAD(P)H quinone oxidoreductase 1 during human liver injury. World J Gastroenterol 12: 1937-1940.
3. Aleksunes LM, Slitt AM, Cherrington NJ, Thibodeau MS, Klaassen CD, Manautou JE. 2005. Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride. Toxicol Sci 83: 44-52.
4. Chan K, Han XD, Kan YW. 2001. An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen. Proc Natl Acad Sci USA 98: 4611-4616.
5. Cho HY, Jedlicka AE, Reddy SP, Kensler TW, Yamamoto M, Zhang LY, Kleeberger SR. 2002. Role of NRF2 in protection against hyperoxic lung injury in mice. Am J Respir Cell Mol Biol 26: 175-182.
6. DeMeo M, Kolli S, Keshavarzian A, et al 1998. Beneficial effect of a bile acid resin binder on enteral feeding induced diarrhea. Am J Gastroenterol 93: 967-971.
7. Hartley DP, Klaassen CD. 2000. Detection of chemical-induced differential expression of rat hepatic cytochrome P450 mRNA transcripts using branched DNA signal amplification technology. Drug Metab Dispos 28: 608-616.
8. Heijne WH, Slitt AL, van Bladeren PJ, et al. 2004. Bromobenzene-induced hepatotoxicity at the transcriptome level. Toxicol Sci 79: 411-422.
9. Huang YT, Hsu YC, Chen CJ, Liu CT, Wei YH. 2003. Oxidative-stress-related changes in the livers of bile-duct-ligated rats. J Biomed Sci 10: 170-178.
10. Ishii T, Itoh K, Yamamoto M. 2002. Roles of Nrf2 in activation of antioxidant enzyme genes via antioxidant responsive elements. Methods Enzymol 348: 182-190.
11. Kitada T, Seki S, Iwai S, Yamada T, Sakaguchi H, Wakasa K. 2001. In situ detection of oxidative DNA damage, 8-hydroxydeoxyguanosine, in chronic human liver disease. J Hepatol 35: 613-618.
12. Liu TZ, Lee KT, Chern CL, Cheng JT, Stern A, Tsai LY. 2001. Free radical-triggered hepatic injury of experimental obstructive jaundice of rats involves overproduction of proinflammatory cytokines and enhanced activation of nuclear factor κB. Ann Clin Lab Sci 31: 383-390.
13. Mathers J, Fraser JA, McMahon M, Saunders RD, Hayes JD, McLellan LI. 2004. Antioxidant and cytoprotective responses to redox stress. Biochem Soc Symp 157-176.
14. Nioi P, McMahon M, Itoh K, Yamamoto M, Hayes JD. 2003. Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence. Biochem J 374: 337-348.
15. Parola M, Leonarduzzi G, Robino G, Albano E, Poli G, Dianzani MU. 1996. On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis. Free Radic Biol Med 20: 351-359.
16. Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW. 2001. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci USA 98: 3410-3415.
17. Ross D. 2004. Quinone reductases multitasking in the metabolic world. Drug Metab Rev 36: 639-654.
18. Siegel D, Gustafson DL, Dehn DL, Han JY, Boonchoong P, Berliner LJ, Ross D. 2004. NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger. Mol Pharmacol 65: 1238-1247.
19. Stedman CA, Liddle C, Coulter SA, et al. 2005. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury. Proc Natl Acad Sci USA 102: 2063-2068.
20. Tsai LY, Lee KT, Liu TZ. 1998. Evidence for accelerated generation of hydroxyl radicals in experimental obstructive jaundice of rats. Free Radic Biol Med 24: 732-737.
21. Vendemiale G, Grattagliano I, Lupo L, Memeo V, Altomare E. 2002. Hepatic oxidative alterations in patients with extra-hepatic cholestasis. Effect of surgical drainage. J Hepatol 37: 601-605.
22. Venugopal R, Jaiswal AK. 1996. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proc Natl Acad Sci USA 93: 14960-14965.
23. Wagner M, Fickert P, Zollner G, et al. 2003. Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice. Gastroenterology 125: 825-838.