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Volumn 45, Issue 2, 2007, Pages 331-339

Mutual changes of thioredoxin and nitrosothiols during biliary cirrhosis: Results from humans and cholestatic rats

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; HYALURONIC ACID; NITRIC OXIDE; NITROSOTHIOL DERIVATIVE; THIOL DERIVATIVE; THIOREDOXIN; UNCLASSIFIED DRUG;

EID: 33847790688     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21519     Document Type: Article
Times cited : (30)

References (50)
  • 1
    • 0029145255 scopus 로고
    • Reduced antioxidative capacity in liver mitochondria from bile duct ligated rats
    • Krahenbuhl S, Talos C, Lauterburg BH, Reichen J. Reduced antioxidative capacity in liver mitochondria from bile duct ligated rats. HEPATOLOGY 1995;22:607-612.
    • (1995) HEPATOLOGY , vol.22 , pp. 607-612
    • Krahenbuhl, S.1    Talos, C.2    Lauterburg, B.H.3    Reichen, J.4
  • 2
    • 0036844813 scopus 로고    scopus 로고
    • Hepatic oxidative alterations in patients with extra-hepatic cholestasis: Effect of surgical drainage
    • Vendemiale G, Grattagliano I, Lupo I., Memeo V, Altomare E. Hepatic oxidative alterations in patients with extra-hepatic cholestasis: effect of surgical drainage. J Hepatol 2002;37:601-605.
    • (2002) J Hepatol , vol.37 , pp. 601-605
    • Vendemiale, G.1    Grattagliano, I.2    Lupo, I.3    Memeo, V.4    Altomare, E.5
  • 3
    • 0027339359 scopus 로고
    • Erythrocyte alterations correlate with CC14 and biliary obstruction-induced liver damage in the rat
    • Muriel P, Favari L, Soto C. Erythrocyte alterations correlate with CC14 and biliary obstruction-induced liver damage in the rat. Life Sci 1993;52:647-655.
    • (1993) Life Sci , vol.52 , pp. 647-655
    • Muriel, P.1    Favari, L.2    Soto, C.3
  • 4
    • 0141593582 scopus 로고    scopus 로고
    • Structural and oxidative modifications of erythrocyte ghosts in patients with primary biliary cirrhosis: Relation with the disease stage and effect of bile acid treatment
    • Grattagliano I, Giudetti AM, Grattagliano V, Palmieri VO, Gnoni GV, Lapadula G, et al. Structural and oxidative modifications of erythrocyte ghosts in patients with primary biliary cirrhosis: relation with the disease stage and effect of bile acid treatment. Eur J Clin Invest 2003;33:868-874.
    • (2003) Eur J Clin Invest , vol.33 , pp. 868-874
    • Grattagliano, I.1    Giudetti, A.M.2    Grattagliano, V.3    Palmieri, V.O.4    Gnoni, G.V.5    Lapadula, G.6
  • 5
    • 2342455104 scopus 로고    scopus 로고
    • Low membrane protein sulfhydrils but not G6PD deficiency predict ribavirin-induced hemolysis in hepatitis C
    • Grattagliano I, Russmann S, Palmieri VO, Juni P, Bihl F, Portincasa P, et al. Low membrane protein sulfhydrils but not G6PD deficiency predict ribavirin-induced hemolysis in hepatitis C. HEPATOLOGY 2004;391248-1255.
    • (2004) HEPATOLOGY , pp. 391248-391255
    • Grattagliano, I.1    Russmann, S.2    Palmieri, V.O.3    Juni, P.4    Bihl, F.5    Portincasa, P.6
  • 6
    • 0035099012 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase in the liver of bile duct-ligated Wistar rats with modulation by lymphomono-nuclear cells
    • Arriero MM, Lopez-Farre A, Fryeiro O, Rodriguez-Feo JA, Velasco S, Garcia-Duran M, et al. Expression of inducible nitric oxide synthase in the liver of bile duct-ligated Wistar rats with modulation by lymphomono-nuclear cells. Surgery 2001;129:255-266.
    • (2001) Surgery , vol.129 , pp. 255-266
    • Arriero, M.M.1    Lopez-Farre, A.2    Fryeiro, O.3    Rodriguez-Feo, J.A.4    Velasco, S.5    Garcia-Duran, M.6
  • 8
    • 0036097310 scopus 로고    scopus 로고
    • Detection of serum nitrite and nitrate in primary biliary cirrhosis: Possible role of nitric oxide in bile duct injury
    • Hokari A, Zeniya M, Esumi H, Kawabe T, Gershwin ME, Toda G. Detection of serum nitrite and nitrate in primary biliary cirrhosis: possible role of nitric oxide in bile duct injury. J Gastroenterol Hepatol 2002;17:308-315.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 308-315
    • Hokari, A.1    Zeniya, M.2    Esumi, H.3    Kawabe, T.4    Gershwin, M.E.5    Toda, G.6
  • 9
    • 0035884860 scopus 로고    scopus 로고
    • Increased formation of S-nitrothiols and nitrotyrosine in cirrhotic rats during endotoxemia
    • Ottesen LH, Harry D, Frost M, Davies S, Khan K, Halliwell B, et al. Increased formation of S-nitrothiols and nitrotyrosine in cirrhotic rats during endotoxemia. Free Radic Biol Med 2001;31:790-798.
    • (2001) Free Radic Biol Med , vol.31 , pp. 790-798
    • Ottesen, L.H.1    Harry, D.2    Frost, M.3    Davies, S.4    Khan, K.5    Halliwell, B.6
  • 10
    • 0036893739 scopus 로고    scopus 로고
    • Enhanced intrahepatic inducible nitric oxide synthase expression and nitrotyrosine accumulation in primary biliary cirrhosis and autoimmune hepatitis
    • Sanz-Cameno P, Medina J, Garcia-Buey L, Garcia-Sanchez A, Borque MJ, Martin-Vilchez S, et al. Enhanced intrahepatic inducible nitric oxide synthase expression and nitrotyrosine accumulation in primary biliary cirrhosis and autoimmune hepatitis. J Hepatol 2002;37:723-729.
    • (2002) J Hepatol , vol.37 , pp. 723-729
    • Sanz-Cameno, P.1    Medina, J.2    Garcia-Buey, L.3    Garcia-Sanchez, A.4    Borque, M.J.5    Martin-Vilchez, S.6
  • 11
    • 0141532278 scopus 로고    scopus 로고
    • Myeloperoxidase-positive inflammatory cells participate in bile duct damage in primary biliary cirrhosis through nitric oxide-mediated reactions
    • Wu CT, Eiserich JP, Ansari AA, Coppel RL, Balasubramanian S, Bowlus CL, et al. Myeloperoxidase-positive inflammatory cells participate in bile duct damage in primary biliary cirrhosis through nitric oxide-mediated reactions. HEPATOLOGY 2003;38:1018-1025.
    • (2003) HEPATOLOGY , vol.38 , pp. 1018-1025
    • Wu, C.T.1    Eiserich, J.P.2    Ansari, A.A.3    Coppel, R.L.4    Balasubramanian, S.5    Bowlus, C.L.6
  • 12
    • 0035584857 scopus 로고    scopus 로고
    • Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
    • Nordberg J, Arner ES. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 2001;31:1287-1312.
    • (2001) Free Radic Biol Med , vol.31 , pp. 1287-1312
    • Nordberg, J.1    Arner, E.S.2
  • 13
    • 0036128974 scopus 로고    scopus 로고
    • Mitochondrial thioredoxin reductase and thiol status
    • Bindoli A, Rigobello MP. Mitochondrial thioredoxin reductase and thiol status. Methods Enzymol 2002;347:307-316.
    • (2002) Methods Enzymol , vol.347 , pp. 307-316
    • Bindoli, A.1    Rigobello, M.P.2
  • 15
    • 0031984162 scopus 로고    scopus 로고
    • Purification of mitochondrial thioredoxin reductase and its involvement in the redox regulation of membrane permeability
    • Rigobello MP, Callegaro MT, Barzon E, Benetti M, Bindoli A. Purification of mitochondrial thioredoxin reductase and its involvement in the redox regulation of membrane permeability. Free Radic Biol Med 1998;24:370-376.
    • (1998) Free Radic Biol Med , vol.24 , pp. 370-376
    • Rigobello, M.P.1    Callegaro, M.T.2    Barzon, E.3    Benetti, M.4    Bindoli, A.5
  • 16
    • 0033168698 scopus 로고    scopus 로고
    • Involvement of thioredoxin in rheumatoid arthritis: Its costimulatory roles in the TNF-alpha-induced production of IL-6 and IL-8 from cultured synovial fibroblasts
    • Yoshida S, Katoh T, Tetsuka T, Uno K, Matsui N, Okamoto T. Involvement of thioredoxin in rheumatoid arthritis: its costimulatory roles in the TNF-alpha-induced production of IL-6 and IL-8 from cultured synovial fibroblasts. J Immunol 1999;163:351-358.
    • (1999) J Immunol , vol.163 , pp. 351-358
    • Yoshida, S.1    Katoh, T.2    Tetsuka, T.3    Uno, K.4    Matsui, N.5    Okamoto, T.6
  • 17
    • 0033532619 scopus 로고    scopus 로고
    • Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells
    • Bertini R, Howard OM, Dong HF, Oppenheim JJ, Bizzarri C, Sergi R, et al. Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells. J Exp Med 1999;189:1783-1789.
    • (1999) J Exp Med , vol.189 , pp. 1783-1789
    • Bertini, R.1    Howard, O.M.2    Dong, H.F.3    Oppenheim, J.J.4    Bizzarri, C.5    Sergi, R.6
  • 18
    • 0029764601 scopus 로고    scopus 로고
    • S-nitrosoglutathione is cleaved by the thioredoxin system with liberation of glutathione and redox regulating nitric oxide
    • Nikitovic D, Holmgren A. S-nitrosoglutathione is cleaved by the thioredoxin system with liberation of glutathione and redox regulating nitric oxide. J Biol Chem 1996;271:19180-19185.
    • (1996) J Biol Chem , vol.271 , pp. 19180-19185
    • Nikitovic, D.1    Holmgren, A.2
  • 19
    • 27844457019 scopus 로고    scopus 로고
    • Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols
    • Stoyanovsky DA, Tyurina YY, Tyurin VA, Anand D, Mandavia DN, Gius D, et al. Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols. J Am Chem Soc 2005;127:15815-15823.
    • (2005) J Am Chem Soc , vol.127 , pp. 15815-15823
    • Stoyanovsky, D.A.1    Tyurina, Y.Y.2    Tyurin, V.A.3    Anand, D.4    Mandavia, D.N.5    Gius, D.6
  • 20
    • 5444240112 scopus 로고    scopus 로고
    • Effect of dietary restriction and N-acetylcysteine supplementation on intestinal mucosa and liver mitochondrial redox status and function in aged rats
    • Grattagliano I, Portincasa P, Cocco T, Moschetta A, Di PM, Palmieri VO, et al. Effect of dietary restriction and N-acetylcysteine supplementation on intestinal mucosa and liver mitochondrial redox status and function in aged rats. Exp Gerontol 2004;39:1323-1332.
    • (2004) Exp Gerontol , vol.39 , pp. 1323-1332
    • Grattagliano, I.1    Portincasa, P.2    Cocco, T.3    Moschetta, A.4    Di, P.M.5    Palmieri, V.O.6
  • 21
    • 0028987969 scopus 로고    scopus 로고
    • Arnelle DR, Stamler JS. NO+, NO, and NO- donation by S-nitrosothiols: implications for regulation of physiological functions by S-nitrosylation and acceleration of disulfide formation. Arch Biochem Biophys 1995;318:279-285.
    • Arnelle DR, Stamler JS. NO+, NO, and NO- donation by S-nitrosothiols: implications for regulation of physiological functions by S-nitrosylation and acceleration of disulfide formation. Arch Biochem Biophys 1995;318:279-285.
  • 22
    • 0028132836 scopus 로고
    • Redox signaling: Nitrosylation and related target interactions of nitric oxide
    • Stamler JS. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 1994;78:931-936.
    • (1994) Cell , vol.78 , pp. 931-936
    • Stamler, J.S.1
  • 23
    • 0026693724 scopus 로고
    • Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin
    • Stamler JS, Jaraki O, Osborne J, Simon DI, Keaney J, Vita J, et al. Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin. Proc Natl Acad Sci U S A 1992;89:7674-7677.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 7674-7677
    • Stamler, J.S.1    Jaraki, O.2    Osborne, J.3    Simon, D.I.4    Keaney, J.5    Vita, J.6
  • 24
    • 0037232972 scopus 로고    scopus 로고
    • Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease
    • Sumida Y, Nakashima T, Yoh T, Furutani M, Hirohama A, Kakisaka Y, et al. Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease. J Hepatol 2003;38:32-38.
    • (2003) J Hepatol , vol.38 , pp. 32-38
    • Sumida, Y.1    Nakashima, T.2    Yoh, T.3    Furutani, M.4    Hirohama, A.5    Kakisaka, Y.6
  • 26
    • 84964193601 scopus 로고
    • Primary biliary cirrhosis
    • Scheuer P. Primary biliary cirrhosis. Proc R Soc Med 1967;60:1257-1260.
    • (1967) Proc R Soc Med , vol.60 , pp. 1257-1260
    • Scheuer, P.1
  • 27
    • 0018399518 scopus 로고
    • Riboflavin and rat hepatic cell structure and function. Mitochondrial oxidative metabolism in deficiency states
    • Hoppel C, DiMarco JP, Tandler B. Riboflavin and rat hepatic cell structure and function. Mitochondrial oxidative metabolism in deficiency states. J Biol Chem 1979;254:4164-4170.
    • (1979) J Biol Chem , vol.254 , pp. 4164-4170
    • Hoppel, C.1    DiMarco, J.P.2    Tandler, B.3
  • 28
    • 0029187491 scopus 로고
    • Thioredoxin and thioredoxin reductase
    • Holmgren A, Bjornstedt M. Thioredoxin and thioredoxin reductase. Methods Enzymol 1995;252:199-208.
    • (1995) Methods Enzymol , vol.252 , pp. 199-208
    • Holmgren, A.1    Bjornstedt, M.2
  • 30
    • 0030198889 scopus 로고    scopus 로고
    • Oxidation of circulating proteins in alcoholics: Role of acetaldehyde and xanthine oxidase
    • Grattagliano I, Vendemiale G, Sabba C, Buonamico P, Altomare E. Oxidation of circulating proteins in alcoholics: role of acetaldehyde and xanthine oxidase. J Hepatol 1996;25:28-36.
    • (1996) J Hepatol , vol.25 , pp. 28-36
    • Grattagliano, I.1    Vendemiale, G.2    Sabba, C.3    Buonamico, P.4    Altomare, E.5
  • 31
    • 0027066985 scopus 로고
    • Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages
    • Schmidt HH, Warner TD, Nakane M, Forstermann U, Murad F. Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages. Mol Pharmacol 1992;41:615-624.
    • (1992) Mol Pharmacol , vol.41 , pp. 615-624
    • Schmidt, H.H.1    Warner, T.D.2    Nakane, M.3    Forstermann, U.4    Murad, F.5
  • 32
    • 33646050895 scopus 로고    scopus 로고
    • Metalloprotein-dependent decomposition of S-nitrosothiols: Studies on the stabilization and measurement of S-nitrosothiols in tissues
    • Mani AR, Ebrahimkhani MR, Ippolito S, Ollosson R, Moore KP. Metalloprotein-dependent decomposition of S-nitrosothiols: studies on the stabilization and measurement of S-nitrosothiols in tissues. Free Radic Biol Med 2006;40:1654-1663.
    • (2006) Free Radic Biol Med , vol.40 , pp. 1654-1663
    • Mani, A.R.1    Ebrahimkhani, M.R.2    Ippolito, S.3    Ollosson, R.4    Moore, K.P.5
  • 33
    • 0027762128 scopus 로고
    • Biological activity of S-nitrosothiols: The role of nitric oxide
    • Mathews WR, Kerr SW. Biological activity of S-nitrosothiols: the role of nitric oxide. J Pharmacol Exp Ther 1993;267:1529-1537.
    • (1993) J Pharmacol Exp Ther , vol.267 , pp. 1529-1537
    • Mathews, W.R.1    Kerr, S.W.2
  • 34
    • 0036154951 scopus 로고    scopus 로고
    • The paradox of nitric oxide in cirrhosis and portal hypertension: Too much, not enough
    • Wiest R, Groszmann RJ. The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough. HEPATOLOGY 2002;35:478-491.
    • (2002) HEPATOLOGY , vol.35 , pp. 478-491
    • Wiest, R.1    Groszmann, R.J.2
  • 35
    • 0035201477 scopus 로고    scopus 로고
    • Arginine reverses ethanol-induced inflammatory and fibrotic changes in liver despite continued ethanol administration
    • Nanji AA, Jokelainen K, Lau GK, Rahemtulla A, Tipoe GL, Polavarapu R, et al. Arginine reverses ethanol-induced inflammatory and fibrotic changes in liver despite continued ethanol administration. J Pharmacol Exp Ther 2001;299:832-839.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 832-839
    • Nanji, A.A.1    Jokelainen, K.2    Lau, G.K.3    Rahemtulla, A.4    Tipoe, G.L.5    Polavarapu, R.6
  • 36
    • 11144269045 scopus 로고    scopus 로고
    • Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice
    • Okuyama H, Nakamura H, Shimahara Y, Uyama N, Kwon YW, Kawada N, et al. Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice. J Hepatol 2005;42:117-123.
    • (2005) J Hepatol , vol.42 , pp. 117-123
    • Okuyama, H.1    Nakamura, H.2    Shimahara, Y.3    Uyama, N.4    Kwon, Y.W.5    Kawada, N.6
  • 37
    • 0036903724 scopus 로고    scopus 로고
    • Endothelial, but not the inducible, nitric oxide synthase is detectable in normal and portal hypertensive rats
    • Stumm MM, D'Orazio D, Sumanovski LT, Martin PY, Reichen J, Sieber CC. Endothelial, but not the inducible, nitric oxide synthase is detectable in normal and portal hypertensive rats. Liver 2002;22:441-450.
    • (2002) Liver , vol.22 , pp. 441-450
    • Stumm, M.M.1    D'Orazio, D.2    Sumanovski, L.T.3    Martin, P.Y.4    Reichen, J.5    Sieber, C.C.6
  • 38
    • 0030273532 scopus 로고    scopus 로고
    • Decreased constitutive hepatic nitric oxide synthase expression in secondary biliary fibrosis and its changes after Roux-en-Y choledocho-jejunostomy in the rat
    • Zimmermann H, Kurzen P, Klossner W, Renner EL, Marti U. Decreased constitutive hepatic nitric oxide synthase expression in secondary biliary fibrosis and its changes after Roux-en-Y choledocho-jejunostomy in the rat. J Hepatol 1996;25:567-573.
    • (1996) J Hepatol , vol.25 , pp. 567-573
    • Zimmermann, H.1    Kurzen, P.2    Klossner, W.3    Renner, E.L.4    Marti, U.5
  • 39
    • 17144389914 scopus 로고    scopus 로고
    • Protective effect of low dose of melatonin against cholestatic oxidative stress after common bile duct ligation in rats
    • Esrefoglu M, Gul M, Emre MH, Polat A, Selimoglu MA. Protective effect of low dose of melatonin against cholestatic oxidative stress after common bile duct ligation in rats. World J Gastroenterol 2005;11:1951-1956.
    • (2005) World J Gastroenterol , vol.11 , pp. 1951-1956
    • Esrefoglu, M.1    Gul, M.2    Emre, M.H.3    Polat, A.4    Selimoglu, M.A.5
  • 40
    • 14644401128 scopus 로고    scopus 로고
    • S-Nitrosothiols: Cellular formation and transport
    • Zhang Y, Hogg N. S-Nitrosothiols: cellular formation and transport. Free Radic Biol Med 2005;38:831-838.
    • (2005) Free Radic Biol Med , vol.38 , pp. 831-838
    • Zhang, Y.1    Hogg, N.2
  • 41
  • 42
    • 11144305211 scopus 로고    scopus 로고
    • The extracellular micro-environment plays a key role in regulating the redox status of cell surface proteins in HIV-infected subjects
    • Sahaf B, Heydari K, Herzenberg LA, Herzenberg LA. The extracellular micro-environment plays a key role in regulating the redox status of cell surface proteins in HIV-infected subjects. Arch Biochem Biophys 2005;434:26-32.
    • (2005) Arch Biochem Biophys , vol.434 , pp. 26-32
    • Sahaf, B.1    Heydari, K.2    Herzenberg, L.A.3    Herzenberg, L.A.4
  • 43
    • 0032560572 scopus 로고    scopus 로고
    • Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione
    • Clementi E, Brown GC, Feelisch M, Moncada S. Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione. Proc Natl Acad Sci U S A 1998;95:7631-7636.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7631-7636
    • Clementi, E.1    Brown, G.C.2    Feelisch, M.3    Moncada, S.4
  • 44
    • 0030697859 scopus 로고    scopus 로고
    • Nitric oxide synthase activity in mitochondria
    • Ghafourifar P, Richter C. Nitric oxide synthase activity in mitochondria. FEBS Lett 1997;418:291-296.
    • (1997) FEBS Lett , vol.418 , pp. 291-296
    • Ghafourifar, P.1    Richter, C.2
  • 46
    • 3042823067 scopus 로고    scopus 로고
    • Mitochondrial nitric oxide synthase drives redox signals for proliferation and quiescence in rat liver development
    • Carreras MC, Converso DP, Lorenti AS, Barbich M, Levisman DM, Jaitovich A, et al. Mitochondrial nitric oxide synthase drives redox signals for proliferation and quiescence in rat liver development. HEPATOLOGY 2004;40:157-166.
    • (2004) HEPATOLOGY , vol.40 , pp. 157-166
    • Carreras, M.C.1    Converso, D.P.2    Lorenti, A.S.3    Barbich, M.4    Levisman, D.M.5    Jaitovich, A.6
  • 47
    • 0347579845 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
    • Nisoli E, Clementi E, Paolucci C, Cozzi V, Tonello C, Sciorati C, et al. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 2003;299:896-899.
    • (2003) Science , vol.299 , pp. 896-899
    • Nisoli, E.1    Clementi, E.2    Paolucci, C.3    Cozzi, V.4    Tonello, C.5    Sciorati, C.6
  • 48
    • 0027767708 scopus 로고
    • Alterations in mitochondrial function and morphology in chronic liver disease: Pathogenesis and potential for therapeutic intervention
    • Krahenbuhl S. Alterations in mitochondrial function and morphology in chronic liver disease: pathogenesis and potential for therapeutic intervention. Pharmacol Ther 1993;60:1-38.
    • (1993) Pharmacol Ther , vol.60 , pp. 1-38
    • Krahenbuhl, S.1
  • 49
    • 24144455258 scopus 로고    scopus 로고
    • Glutathione depletion renders rat hepatocytes sensitive to nitric oxide donor-mediated toxicity
    • Chen T, Pearce LL, Peterson J, Stoyanovsky D, Billiar TR. Glutathione depletion renders rat hepatocytes sensitive to nitric oxide donor-mediated toxicity. HEPATOLOGY 2005;42:598-607.
    • (2005) HEPATOLOGY , vol.42 , pp. 598-607
    • Chen, T.1    Pearce, L.L.2    Peterson, J.3    Stoyanovsky, D.4    Billiar, T.R.5
  • 50
    • 0036374139 scopus 로고    scopus 로고
    • Increased nitric oxide production in hepatocytes is involved in liver dysfunction following obstructive jaundice
    • Tu W, Kitade H, Satoi S, Zhang ZT, Kaibori M, Kwon AH, et al. Increased nitric oxide production in hepatocytes is involved in liver dysfunction following obstructive jaundice. J Surg Res 20021;106:31-36.
    • (2002) J Surg Res , vol.106 , Issue.1 , pp. 31-36
    • Tu, W.1    Kitade, H.2    Satoi, S.3    Zhang, Z.T.4    Kaibori, M.5    Kwon, A.H.6


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