Epigallocatechin-3-gallate inhibits growth of activated hepatic stellate cells by enhancing the capacity of glutathione synthesis

Molecular Pharmacology

Volumn 73, Issue 5, 2008, Pages 1465-1473

  Fu, Yumei ^a   Zheng, Shizhong ^a,b   Lu, Shelly C ^c   Chen, Anping ^a,b  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; BUTHIONINE SULFOXIMINE; EPIGALLOCATECHIN GALLATE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE ETHYL ESTER; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; CATECHIN; DRUG DERIVATIVE; GLUTATHIONE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSOL; DRUG INHIBITION; GENE EXPRESSION; GENETIC TRANSFECTION; GLUTATHIONE METABOLISM; GROWTH INHIBITION; MALE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; STELLATE CELL; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CYTOLOGY; CYTOPLASM; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; LIVER CELL; LIVER MITOCHONDRION; METABOLISM; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; BUTHIONINE SULFOXIMINE; CATECHIN; CELL PROLIFERATION; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HEPATOCYTES; MALE; MITOCHONDRIA, LIVER; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 42449089421     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.040634     Document Type: Article

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