Protective mechanism of KIOM-4 in streptozotocin-induced pancreatic β-cells damage is involved in the inhibition of endoplasmic reticulum stress

Evidence-based Complementary and Alternative Medicine

Volumn 2011, Issue , 2011, Pages

  Hyun, Jin Won ^a   Zhang, Rui ^a   Kim, Jin Sook ^b   Kang, Kyoung Ah ^a   Piao, Mei Jing ^a   Kim, Ki Cheon ^a  

^a Jeju National University School of Medicine   (South Korea)

^b Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CALCIUM ION; CASPASE 12; CCAAT ENHANCER BINDING PROTEIN; EUPHORBIA EXTRACT; EUPHORBIA PEKINENSIS EXTRACT; GLUCOSE REGULATED PROTEIN 78; GLYCYRRHIZA URALENSIS EXTRACT; KIOM 4; MAGNOLIA OFFICINALIS EXTRACT; MEMBRANE PROTEIN; PLANT EXTRACT; PROTEIN KINASE; PUERARIA EXTRACT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; ENZYME PHOSPHORYLATION; EUPHORBIA; FLUORESCENCE MICROSCOPY; GLYCYRRHIZA URALENSIS; INSULIN DEPENDENT DIABETES MELLITUS; MAGNOLIACEAE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PUERARIA; RAT; RNA INTERFERENCE; STREPTOZOCIN DIABETES; WESTERN BLOTTING;

EID: 77958512943     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2011/231938     Document Type: Article

References (58)

1. Saito J., Sakai Y., Nagase H., In vitro anti-mutagenic effect of magnolol against direct and indirect mutagens Mutation Research 2006 609 1 68 73
2. Park E. J., Kim S. Y., Zhao Y. Z., Sohn D. H., Honokiol reduces oxidative stress, c-jun-NH2-terminal kinase phosphorylation and protects against glycochenodeoxycholic acid-induced apoptosis in primary cultured rat hepatocytes Planta Medica 2006 72 7 661 664
3. Cao A. H., Vo L. T., King R. G., Honokiol protects against carbon tetrachloride induced liver damage in the rat Phytotherapy Research 2005 19 11 932 937
4. Lin Y. R., Chen H. H., Ko C. H., Chan M. H., Neuroprotective activity of honokiol and magnolol in cerebellar granule cell damage European Journal of Pharmacology 2006 537 1-3 64 69
5. Lee J., Jung E., Park J., Jung K., Lee S., Hong S., Park J., Park E., Kim J., Park S., Park D., Anti-inflammatory effects of magnolol and honokiol are mediated through inhibition of the downstream pathway of MEKK-1 in NF- B activation signaling Planta Medica 2005 71 4 338 343
6. Ho K. Y., Tsai C. C., Chen C. P., Huang J. S., Lin C. C., Antimicrobial activity of honokiol and magnolol isolated from Magnolia officinalis Phytotherapy Research 2001 15 2 139 141
7. Lee S. J., Cho Y. H., Park K., Kim E. J., Kang B. S., Jung K. H., Kim C. H., Kim W. J., Moon S. K., Inhibitory effects of the aqueous extract of Magnolia officinalis on the responses of human urinary bladder cancer 5637 cells in vitro and mouse urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in vitro Phytotherapy Research 2009 23 1 20 27
8. Tam W. Y., Chook P., Qiao M., Chan L. T., Chan T. Y. K., Poon Y. K., Fung K. P., Leung P. C., Woo K. S., The efficacy and tolerability of adjunctive alternative herbal medicine (Salvia miltiorrhiza and Pueraria lobata) on vascular function and structure in coronary patients Journal of Alternative and Complementary Medicine 2009 15 4 415 421
9. Miyazawa M., Sakano K., Nakamura S. I., Kosaka H., Antimutagenic activity of isoflavone from Pueraria lobata Journal of Agricultural and Food Chemistry 2001 49 1 336 341
10. Lee K. T., Sohn I. C., Kim D. H., Choi J. W., Kwon S. H., Park H. J., Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro Archives of Pharmacal Research 2000 23 5 461 466
11. Lee K. T., Sohn I. C., Kim Y. K., Choi J. H., Choi J. W., Park H. J., Itoh Y., Miyamoto K. I., Tectorigenin, an isoflavone of Pueraria thunbergiana BENTH., induces differentiation and apoptosis in human promyelocytic leukemia HL-60 cells Biological and Pharmaceutical Bulletin 2001 24 10 1117 1121
12. Liao H., Banbury L. K., Leach D. N., Elucidation of Danzhixiaoyao Wan and its constituent herbs on antioxidant activity and inhibition of nitric oxide production Evidence-Based Complementary and Alternative Medicine 2007 4 4 425 430
13. Wang Z. Y., Nixon D. W., Licorice and cancer Nutrition and Cancer 2001 39 1 1 11
14. Popovich D. G., Yeo S. Y., Zhang W., Ginseng (Panax quinquefolius) and Licorice (Glycyrrhiza uralensis) root extract combinations increase hepatocarcinoma cell (Hep-G2) viability. Evidence-Based Complementary and Alternative Medicine. In press
15. Ahn M. J., Chul Y. K., Ji S. L., Tae G. K., Seung H. K., Lee C. K., Lee B. B., Shin C. G., Huh H., Kim J., Inhibition of HIV-1 integrase by galloyl glucoses from Terminalia chebula and flavonol glycoside gallates from Euphorbia pekinensis Planta Medica 2002 68 5 457 459
16. Kong L. Y., Li Y., Wu X. L., Min Z. D., Cytotoxic diterpenoids from Euphorbia pekinensis Planta Medica 2002 68 3 249 252
17. Kang K. A., Kim J. S., Hyun J. W., KIOM-4 protects RINm5F pancreatic -cells against streptozotocin induced oxidative stress in vitro Biotechnology and Bioprocess Engineering 2008 13 2 150 157
18. Kang K. A., Kim J. S., Zhang R., Piao M. J., Chang W. Y., Kim K. C., Kim G. Y., Jin M., Hyun J. W., Protective mechanism of KIOM-4 against streptozotocin induced diabetic cells: Involvement of heme oxygenase-1 Biotechnology and Bioprocess Engineering 2009 14 3 295 301
19. Kang K. A., Kim J. S., Zhang R., KIOM-4 protects against oxidative stress-induced mitochondrial damage in pancreatic -cells via its antioxidant effects. Evidence-Based Complementary and Alternative Medicine. In press
20. Mathis D., Vence L., Benoist C., -cell death during progression to diabetes Nature 2001 414 6865 792 798
21. Maytin E. V., Habener J. F., Transcription factors C/EBP, C/EBP, and CHOP (Gadd153) expressed during the differentiation program of keratinocytes in vitro and in vivo Journal of Investigative Dermatology 1998 110 3 238 246
22. Heller B., Wang Z. Q., Wagner E. F., Radons J., Burkle A., Fehsel K., Burkart V., Kolb H., Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells The Journal of Biological Chemistry 1995 270 19 11176 11180
23. Eizirik D. L., Mandrup-Poulsen T., A choice of deaththe signal-transduction of immune-mediated beta-cell apoptosis Diabetologia 2001 44 12 2115 2133
24. Mori K., Tripartite management of unfolded proteins in the endoplasmic reticulum Cell 2000 101 5 451 454
25. Kaufman R. J., Scheuner D., Schrder M., Shen X., Lee K., Liu C. Y., Arnold S. M., The unfolded protein response in nutrient sensing and differentiation Nature Reviews Molecular Cell Biology 2002 3 6 411 421
26. Oyadomari S., Araki E., Mori M., Endoplasmic reticulum stress-mediated apoptosis in pancreatic -cells Apoptosis 2002 7 4 335 345
27. Araki E., Oyadomari S., Mori M., Endoplasmic reticulum stress and diabetes mellitus Internal Medicine 2003 42 1 7 14
28. Laybutt D. R., Preston A. M., kerfeldt M. C., Kench J. G., Busch A. K., Biankin A. V., Biden T. J., Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes Diabetologia 2007 50 4 752 763
29. Malhotra J. D., Miao H., Zhang K., Wolfson A., Pennathur S., Pipe S. W., Kaufman R. J., Antioxidants reduce endoplasmic reticulum stress and improve protein secretion Proceedings of the National Academy of Sciences of the United States of America 2008 105 47 18525 18530
30. Haynes C. M., Titus E. A., Cooper A. A., Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death Molecular Cell 2004 15 5 767 776
31. Malhotra J. D., Miao H., Zhang K., Wolfson A., Pennathur S., Pipe S. W., Kaufman R. J., Antioxidants reduce endoplasmic reticulum stress and improve protein secretion Proceedings of the National Academy of Sciences of the United States of America 2008 105 47 18525 18530
32. Wataha J. C., Hanks C. T., Craig R. G., The in vitro effects of metal cations on eukaryotic cell metabolism Journal of Biomedical Materials Research 1991 25 9 1133 1149
33. Carmichael J., DeGraff W. G., Gazdar A. F., Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing Cancer Research 1987 47 4 936 942 (Pubitemid 17027905)
34. Hajnoczky G., Robb-Gaspers L. D., Seitz M. B., Thomas A. P., Decoding of cytosolic calcium oscillations in the mitochondria Cell 1995 82 3 415 424
35. Cullinan S. B., Diehl J. A., Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway International Journal of Biochemistry and Cell Biology 2006 38 3 317 332
36. Savory J., Herman M. M., Ghribi O., Intracellular mechanisms underlying aluminum-induced apoptosis in rabbit brain Journal of Inorganic Biochemistry 2003 97 1 151 154
37. Schrder M., Kaufman R. J., The mammalian unfolded protein response Annual Review of Biochemistry 2005 74 739 789
38. Ferri K. F., Kroemer G., Organelle-specific initiation of cell death pathways Nature Cell Biology 2001 3 11 E255 263
39. Abdelrahim M., Newman K., Vanderlaag K., Samudio I., Safe S., 3, 3′ -Diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5 Carcinogenesis 2006 27 4 717 728
40. Jiang H. Y., Wek R. C., Phosphorylation of the -subunit of the eukaryotic initiation factor-2 (eIF2 ) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition The Journal of Biological Chemistry 2005 280 14 14189 14202
41. Moenner M., Pluquet O., Bouchecareilh M., Chevet E., Integrated endoplasmic reticulum stress responses in cancer Cancer Research 2007 67 22 10631 10634
42. Oyadomari S., Mori M., Roles of CHOP/GADD153 in endoplasmic reticulum stress Cell Death and Differentiation 2004 11 4 381 389
43. Rao R. V., Ellerby H. M., Bredesen D. E., Coupling endoplasmic reticulum stress to the cell death program Cell Death and Differentiation 2004 11 4 372 380
44. Jang Y. Y., Song J. H., Shin Y. K., Han E. S., Lee C. S., Protective effect of boldine on oxidative mitochondrial damage in streptozotocin-induced diabetic rats Pharmacological Research 2000 42 4 361 371
45. Zhang L., Zalewski A., Liu Y., Mazurek T., Cowan S., Martin J. L., Hofmann S. M., Vlassara H., Shi Y., Diabetes-induced oxidative stress and low-grade inflammation in porcine coronary arteries Circulation 2003 108 4 472 478
46. Lim J. H., Park J. W., Kim S. H., Choi Y. H., Choi K. S., Kwon T. K., Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C- -independent pathway in human colon cancer cells Apoptosis 2008 13 11 1378 1385
47. Harding H. P., Calfon M., Urano F., Novoa I., Ron D., Transcriptional and translational control in the mammalian unfolded protein response Annual Review of Cell and Developmental Biology 2002 18 575 599
48. Zhang K., Kaufman R. J., Signaling the unfolded protein response from the endoplasmic reticulum The Journal of Biological Chemistry 2004 279 25 25935 25938 (Pubitemid 38798732)
49. Schrder M., Kaufman R. J., The mammalian unfolded protein response Annual Review of Biochemistry 2005 74 739 789
50. Wu J., Kaufman R. J., From acute ER stress to physiological roles of the unfolded protein response Cell Death and Differentiation 2006 13 3 374 384
51. Wang X. Z., Lawson B., Brewer J. W., Zinszner H., Sanjay A., Mi L. J., Boorstein R., Kreibich G., Hendershot L. M., Ron D., Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153) Molecular and Cellular Biology 1996 16 8 4273 4280
52. Barone M. V., Crozat A., Tabaee A., Philipson L., Ron D., CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest Genes and Development 1994 8 4 453 464
53. Matsumoto M., Minami M., Takeda K., Sakao Y., Akira S., Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells FEBS Letters 1996 395 2-3 143 147
54. Gotoh T., Oyadomari S., Mori K., Mori M., Nitric oxide-induced apoptosis in RAW 264.7 Macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP The Journal of Biological Chemistry 2002 277 14 12343 12350
55. Zinszner H., Kuroda M., Wang X., Batchvarova N., Lightfoot R. T., Remotti H., Stevens J. L., Ron D., CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum Genes and Development 1998 12 7 982 995
56. Oyadomari S., Takeda K., Takiguchi M., Gotoh T., Matsumoto M., Wada I., Akira S., Araki E., Mori M., Nitric oxide-induced apoptosis in pancreatic -cells is mediated by the endoplasmic reticulum stress pathway Proceedings of the National Academy of Sciences of the United States of America 2001 98 19 10845 10850
57. Oyadomari S., Koizumi A., Takeda K., Gotoh T., Akira S., Araki E., Mori M., Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes The Journal of Clinical Investigation 2002 109 4 525 532
58. Pino S. C., O'Sullivan-Murphy B., Lidstone E. A., Yang C., Lipson K. L., Jurczyk A., Dilorio P., Brehm M. A., Mordes J. P., Greiner D. L., Rossini A. A., Bortell R., CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells PLoS ONE 2009 4 5