Novel agonists and antagonists for human protease activated receptor 2

Journal of Medicinal Chemistry

Volumn 53, Issue 20, 2010, Pages 7428-7440

  Barry, Grant D ^a   Suen, Jacky Y ^a   Le, Giang T ^a   Cotterell, Adam ^a   Reid, Robert C ^a   Fairlie, David P ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN 1 AMINO NAPHTHALENE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN 1 AMINOBIPHENYL; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN 3 AMINO 1 [4 [(AMINOMETHYL)PIPERIDIN 1 YL] 4 METHYL 1 OXOPENTAN 2 YL]PYRROLIDIN 2 ONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN 3,4 DIHYDROISOQUINOLINE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN 4 (TOLYL)PIPERAZINE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN 4 AMINOPHENYL (4 MORPHOLIN 1 YL)ETHAN 2 ONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN 4 AMINOPHENYL [4 (AMINOMETHYL)PIPERIDIN1 YL]METHANONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN 4 [(AMINOMETHYL)PHENYL] [4 (AMINOMETHYL)PIPERIDIN1 YL]METHANONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN 6 AMINO 3 [4 (AMINOMETHYL)PIPERIDIN 1 CARBONYL]TETRAHYDRO 2H THIAZOLO(3,2 A)PYRIDIN 5(3H)ONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN AMINO 3 [(AMINOMETHYL)PHENYL][4 (AMINOMETHYL)PIPERIDIN 1 YL]METHANONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN AMINO 3 [(PYRIDIN 3 YL)METHYLAMINO]PROPAN 3 ONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN AMINO 5 AMINOPENTANE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN AMINO [3 (4 AMINOMETHYL)PIPERIDIN 1 YL]PENTAN 5 ONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN AMINO [3 (4 AMINOMETHYL)PIPERIDIN 1 YL]PROPAN 3 ONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN AMINO [5 (4 AMINOMETHYL)PIPERIDIN 1 YL]PENTAN 5 ONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN SPIROINDANE 1,4' PIPERIDINE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN(3 AMINOPHENYL) [4 (AMINOMETHYL)PIPERIDIN1 YL]METHANONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN(4 AMINOPHENYL) [4 (AMINOMETHYL)PIPERIDIN1 YL]METHANONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN(PIPERIDIN 2 YL) [4 (AMINOMETHYL)PIPERIDIN1 YL]METHANONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN(PIPERIDIN 3 YL) [4 (AMINOMETHYL)PIPERIDIN1 YL]METHANONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN(PIPERIDIN 4 YL)[4 (AMINOMETHYL)PIPERIDIN1 YL]METHANONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCINAMINO 3 [(PYRIDIN 3 YL)METHYLAMINO]PENTAN 5 ONE; 5 ISOXAZOYL CYCLOHEXYLALANIN ISOLEUCIN[(4 PHENYL)PIPERAZINE]; 5 ISOXAZOYL CYCLOHEXYLALANIN OLE AMINO 3 AMINOPROPANE; GB 110; GB 83; PEPTIDE DERIVATIVE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; UNCLASSIFIED DRUG; UNINDEXED DRUG; 5-ISOXAZOYL-CYCLOHEXYLALANYL-ISOLEUCYL-(3-(AMINOMETHYL)PHENYL)-(4-(AMINOMETHYL)PIPERIDIN-1-YL)METHANONE; 5-ISOXAZOYL-CYCLOHEXYLALANYL-ISOLEUCYL-SPIROINDANE-1,4'-PIPERIDINE; CALCIUM; DIPEPTIDE; ISOXAZOLE DERIVATIVE; OLIGOPEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; DRUG BIOAVAILABILITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STABILITY; DRUG TARGETING; EMBRYO; HUMAN; HUMAN CELL; IN VIVO STUDY; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION; AGONISTS; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; IN VITRO STUDY; METABOLISM; SERUM; SYNTHESIS;

CALCIUM; CELL LINE; DIPEPTIDES; DRUG STABILITY; HUMANS; IN VITRO TECHNIQUES; ISOXAZOLES; OLIGOPEPTIDES; RECEPTOR, PAR-2; SERUM;

EID: 77958486918     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100984y     Document Type: Article

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