PAR-2 activation in intestinal epithelial cells potentiates interleukin-1β-induced chemokine secretion via MAP kinase signaling pathways

Cytokine

Volumn 31, Issue 5, 2005, Pages 358-367

  Fyfe, Meredith ^a   Bergström, Monica ^a   Aspengren, Sara ^b   Peterson, Anders ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

ERK; Interleukin 8; NF B; p38; Proteinase activated receptor 2 (PAR 2)

Indexed keywords

CHEMOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PEPTIDE; PROTEINASE ACTIVATED RECEPTOR 2; SYNTHETIC ACTIVATING PEPTIDE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; CYTOKINE RELEASE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; CACO-2 CELLS; CELL LINE, TUMOR; CHEMOKINES; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; INFLAMMATION; INTERLEUKIN-1; INTERLEUKIN-8; INTESTINES; LIGANDS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDES; PHOSPHORYLATION; RECEPTOR, PAR-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; UP-REGULATION;

EID: 23944450604     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2005.06.004     Document Type: Article

References (36)

1. R.B. Sartor Cytokines in intestinal inflammation: pathophysiological and clinical considerations Gastroenterology 106 2 1994 533 539
2. S.J. Van Deventer Tumour necrosis factor and Crohn's disease Gut 40 4 1997 443 448
3. N. Cenac, A.M. Coelho, C. Nguyen, S. Compton, P. Andrade-Gordon, and W.K. MacNaughton Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2 Am J Pathol 161 5 2002 1903 1915
4. W.J. Tremaine, A. Brzezinski, J.A. Katz, D.C. Wolf, T.J. Fleming, and J. Mordenti Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study Alimentary Pharmacology and Therapeutics 16 3 2002 407 413
5. O. Dery, C.U. Corvera, M. Steinhoff, and N.W. Bunnett Proteinase-activated receptors: novel mechanisms of signalling by serine proteases Am J Physiol 274 6 Pt 1 1998 C1429 C1452
6. N. Vergnolle, J.L. Wallace, N.W. Bunnett, and M.D. Hollenberg Protease-activated receptors in inflammation, neuronal signalling and pain Trends Pharmacol Sci 22 3 2001 146 152
7. S.K. Bohm, W. Kong, D. Bromme, S.P. Smeekens, D.C. Anderson, and A. Connolly Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2 Biochem J 314 Pt 3 1996 1009 1016
8. S. Nystedt, K. Emilsson, A.K. Larsson, B. Strombeck, and J. Sundelin Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2 Eur J Biochem 232 1 1995 84 89
9. M. Baggiolini, P. Loetscher, and B. Moser Interleukin-8 and the chemokine family Int J Immunopharmacol 17 2 1995 103 108
10. L. Mazzucchelli, C. Hauser, K. Zgraggen, H. Wagner, M. Hess, and J.A. Laissue Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation Am J Pathol 144 5 1994 997 1007
11. R.D. Fusunyan, J.J. Quinn, Y. Ohno, R.P. MacDermott, and I.R. Sanderson Butyrate enhances interleukin (IL)-8 secretion by intestinal epithelial cells in response to IL-1beta and lipopolysaccharide Pediatr Res 43 1 1998 84 90
12. L. Chi, Y. Li, L. Stehno-Bittel, J. Gao, D.C. Morrison, and D.J. Stechschulte Interleukin-6 production by endothelial cells via stimulation of protease-activated receptors is amplified by endotoxin and tumor necrosis factor-alpha J Interferon Cytokine Res 21 4 2001 231 240
13. G. Rogler, K. Brand, D. Vogl, S. Page, R. Hofmeister, and T. Andus Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa Gastroenterology 115 2 1998 357 369
14. S. Schreiber, S. Nikolaus, and J. Hampe Activation of nuclear factor kappa B in inflammatory bowel disease Gut 42 4 1998 477 484
15. M.F. Neurath, S. Pettersson, K.H. Meyer zum Buschenfelde, and W. Strober Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice Nat Med 2 9 1996 998 1004
16. F. Yan, and D.B. Polk Aminosalicylic acid inhibits IκB kinase alpha phosphorylation of IκBα in mouse intestinal epithelial cells J Biol Chem 274 51 1999 36631 36636
17. V.M. Shpacovitch, T. Brzoska, J. Buddenkotte, C. Stroh, C.P. Sommerhoff, and J.C. Ansel Agonists of proteinase-activated receptor 2 induce cytokine release and activation of nuclear transcription factor kappaB in human dermal microvascular endothelial cells J Invest Dermatol 118 2 2002 380 385
18. E. Bretschneider, R. Kaufmann, M. Braun, M. Wittpoth, E. Glusa, and G. Nowak Evidence for proteinase-activated receptor-2 (PAR-2)-mediated mitogenesis in coronary artery smooth muscle cells Br J Pharmacol 126 8 1999 1735 1740
19. T. Kanke, S.R. Macfarlane, M.J. Seatter, E. Davenport, A. Paul, and R.C. McKenzie Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes J Biol Chem 276 34 2001 31657 31666
20. E. Hoffmann, O. Dittrich-Breiholz, H. Holtmann, and M. Kracht Multiple control of interleukin-8 gene expression J Leukocyte Biol 72 5 2002 847 855
21. H. Harant, R. de Martin, P.J. Andrew, E. Foglar, C. Dittrich, and I.J. Lindley Synergistic activation of interleukin-8 gene transcription by all-trans-retinoic acid and tumor necrosis factor-alpha involves the transcription factor NF-kappaB J Biol Chem 271 43 1996 26954 26961
22. N. Mukaida, Y. Mahe, and K. Matsushima Cooperative interaction of nuclear factor-kappa B- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines J Biol Chem 265 34 1990 21128 21133
23. T. Kasahara, N. Mukaida, K. Yamashita, H. Yagisawa, T. Akahoshi, and K. Matsushima IL-1 and TNF-alpha induction of IL-8 and monocyte chemotactic and activating factor (MCAF) mRNA expression in a human astrocytoma cell line Immunology 74 1 1991 60 67
24. A.R. Brasier, M. Jamaluddin, A. Casola, W. Duan, Q. Shen, and R.P. Garofalo A promoter recruitment mechanism for tumor necrosis factor-alpha-induced interleukin-8 transcription in type II pulmonary epithelial cells. Dependence on nuclear abundance of Rel A, NF-kappaB1, and c-Rel transcription factors J Biol Chem 273 6 1998 3551 3561
25. M. Aihara, D. Tsuchimoto, H. Takizawa, A. Azuma, H. Wakebe, and Y. Ohmotot Mechanisms involved in Helicobacter pylori-induced interleukin-8 production by a gastric cancer cell line, MKN45 Infect Immun 65 8 1997 3218 3224
26. S. Hobbie, L.M. Chen, R.J. Davis, and J.E. Galan Involvement of mitogen-activated protein kinase pathways in the nuclear responses and cytokine production induced by Salmonella typhimurium in cultured intestinal epithelial cells J Immunol 159 11 1997 5550 5559
27. J.G. Mastronarde, M.M. Monick, N. Mukaida, K. Matsushima, and G.W. Hunninghake Activator protein-1 is the preferred transcription factor for cooperative interaction with nuclear factor-kappaB in respiratory syncytial virus-induced interleukin-8 gene expression in airway epithelium J Infect Dis 177 5 1998 1275 1281
28. T. Murayama, Y. Ohara, M. Obuchi, K.S. Khabar, H. Higashi, and N. Mukaida Human cytomegalovirus induces interleukin-8 production by a human monocytic cell line, THP-1, through acting concurrently on AP-1- and NF-kappaB-binding sites of the interleukin-8 gene J Virol 71 7 1997 5692 5695
29. G.D. Wu, N. Huang, X. Wen, S.A. Keilbaugh, and H. Yang High-level expression of I kappa B-beta in the surface epithelium of the colon: in vitro evidence for an immunomodulatory role J Leukocyte Biol 66 6 1999 1049 1056
30. H. Holtmann, J. Enninga, S. Kalble, A. Thiefes, A. Dorrie, and M. Broemer The MAPK kinase kinase TAK1 plays a central role in coupling the interleukin-1 receptor to both transcriptional and RNA-targeted mechanisms of gene regulation J Biol Chem 276 5 2001 3508 3516
31. R. Winzen, M. Kracht, B. Ritter, A. Wilhelm, C.Y. Chen, and A.B. Shyu The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism EMBO J 18 18 1999 4969 4980
32. P.A. Scherle, E.A. Jones, M.F. Favata, A.J. Daulerio, M.B. Covington, and S.A. Nurnberg Inhibition of MAP kinase kinase prevents cytokine and prostaglandin E2 production in lipopolysaccharide-stimulated monocytes J Immunol 161 10 1998 5681 5686
33. W. Chen, M.M. Monick, A.B. Carter, and G.W. Hunninghake Activation of ERK2 by respiratory syncytial virus in A549 cells is linked to the production of interleukin 8 Exp Lung Res 26 1 2000 13 26
34. H.B. Jijon, W.J. Panenka, K.L. Madsen, and H.G. Parsons MAP kinases contribute to IL-8 secretion by intestinal epithelial cells via a posttranscriptional mechanism Am J Physiol Cell Physiol 283 1 2002 C31 C41
35. K. Page, V. Hughes, K. Odoms, K. Dunsmore, and M. Hershenson German cockroach proteases regulate interleukin-8 expression via nuclear factor for interleukin-6 in human bronchial epithelial cells Am J Respir Cell Mol Biol 32 2005 225 231
36. K. Iwakiri, M. Ghazizadeh, E. Jin, M. Fujiwara, T. Takemura, and S. Takezaki Human airway trypsin-like protease induces PAR-2-mediated IL-8 release in psoriasis vulgaris J Invest Dermatol 122 2004 937 944