Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [ 3H]2-furoyl-LIGRL-NH 2, to human PAR2

British Journal of Pharmacology

Volumn 145, Issue 2, 2005, Pages 255-263

  Kanke, Toru ^a   Ishiwata, Hiroyuki ^a   Kabeya, Mototsugu ^a   Saka, Masako ^a   Doi, Takeshi ^a   Hattori, Yukio ^a   Kawabata, Atsufumi ^b   Plevin, Robin ^c  

^a Kowa Company Limited   (Japan)

^b KINKI UNIVERSITY   (Japan)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

3H 2 furoyl LIGRL NH 2; Agonist; HCT 15 cells; HUVEC; NCTC7244 cells; Protease activated receptor 2 (PAR2); Radioligand binding; Trypsin

Indexed keywords

2 FUROYLLEUCYLISOLEUCYLGLYCYLARGINYLLEUCINAMIDE; PEPTIDE; PROTEINASE ACTIVATED RECEPTOR 2; RADIOLIGAND; SERINE; SERYLLEUCYLISOLEUCYLGLYCYLLYSYLVALINE; TRITIUM; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM MOBILIZATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; HUMAN; HUMAN CELL; LIGAND BINDING; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

BINDING SITES; BINDING, COMPETITIVE; CALCIUM; CELL LINE; CELL LINE, TUMOR; HUMANS; LIGANDS; OLIGOPEPTIDES; RADIOLIGAND ASSAY; RECEPTOR, PAR-2; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN;

EID: 19944369803     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706189     Document Type: Article

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