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Volumn 55, Issue 3, 2006, Pages 271-278

PAR-2 deficient CD4+ T cells exhibit downregulation of IL-4 and upregulation of IFN-γ after antigen challenge in mice

Author keywords

GATA 3; JNK1; PAR 2; T bet

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEINASE ACTIVATED RECEPTOR 2;

EID: 33748921366     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.55.271     Document Type: Article
Times cited : (13)

References (29)
  • 3
    • 0031744875 scopus 로고    scopus 로고
    • Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases
    • Dery O, Corvera CU, Steinhoff M, Bunnett NW. Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am. J. Physiol. 1998;274:C1429-1452.
    • (1998) Am. J. Physiol. , vol.274
    • Dery, O.1    Corvera, C.U.2    Steinhoff, M.3    Bunnett, N.W.4
  • 4
    • 0036262319 scopus 로고    scopus 로고
    • International Union of Pharmacology. XX-VIII. Proteinase-Activated Receptors
    • Hollenberg MD, Compton S. International Union of Pharmacology. XX-VIII. Proteinase-Activated Receptors. Pharmacol. Rev. 2002;54:203-217.
    • (2002) Pharmacol. Rev. , vol.54 , pp. 203-217
    • Hollenberg, M.D.1    Compton, S.2
  • 5
    • 15444346942 scopus 로고    scopus 로고
    • Interactions of mast cell tryptase with thrombin receptors and PAR-2
    • Molino M, Barnathan ES, Numerof R et al. Interactions of mast cell tryptase with thrombin receptors and PAR-2. J. Biol. Chem. 1997;272:4043-4049.
    • (1997) J. Biol. Chem. , vol.272 , pp. 4043-4049
    • Molino, M.1    Barnathan, E.S.2    Numerof, R.3
  • 6
    • 0030727854 scopus 로고    scopus 로고
    • Identification of potential activators of proteinase-activated receptor-2
    • Fox MT, Harriott P, Walker B, Stone SR. Identification of potential activators of proteinase-activated receptor-2. FEBS Lett. 1997;417:267-269.
    • (1997) FEBS Lett. , vol.417 , pp. 267-269
    • Fox, M.T.1    Harriott, P.2    Walker, B.3    Stone, S.R.4
  • 7
    • 0034624973 scopus 로고    scopus 로고
    • Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
    • Camerer E, Huang W, Coughlin SR. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc. Natl. Acad. Sci. U.S.A. 2000;97:5255-5260.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 5255-5260
    • Camerer, E.1    Huang, W.2    Coughlin, S.R.3
  • 8
    • 15844401726 scopus 로고    scopus 로고
    • The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells
    • Nystedt S, Ramakrishnan V, Sundelin J. The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. J. Biol. Chem. 1996;271:14910-14915.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14910-14915
    • Nystedt, S.1    Ramakrishnan, V.2    Sundelin, J.3
  • 9
    • 0032708759 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo
    • Vergnolle N. Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo. J. Immunol. 1999;163:5064-5069.
    • (1999) J. Immunol. , vol.163 , pp. 5064-5069
    • Vergnolle, N.1
  • 10
    • 0031690091 scopus 로고    scopus 로고
    • Increased vascular permeability by a specific agonist of protease-activated receptor-2 in rat hindpaw
    • Kawabata A, Kuroda R, Minami T, Kataoka K, Taneda M. Increased vascular permeability by a specific agonist of protease-activated receptor-2 in rat hindpaw. Brit. J. Pharmacol. 1998;125:419-422.
    • (1998) Brit. J. Pharmacol. , vol.125 , pp. 419-422
    • Kawabata, A.1    Kuroda, R.2    Minami, T.3    Kataoka, K.4    Taneda, M.5
  • 11
    • 0032792955 scopus 로고    scopus 로고
    • Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw
    • Vergnolle N, Hollengerg MD, Sharkey KA, Wallace JL. Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw. Brit. J. Pharmacol. 1999;127:1083-1090.
    • (1999) Brit. J. Pharmacol. , vol.127 , pp. 1083-1090
    • Vergnolle, N.1    Hollengerg, M.D.2    Sharkey, K.A.3    Wallace, J.L.4
  • 12
    • 0036166557 scopus 로고    scopus 로고
    • Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear
    • Kawagoe J, Takizawa T, Matsumoto J et al. Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear. Jpn. J. Pharmacol. 2002;88:77-84.
    • (2002) Jpn. J. Pharmacol. , vol.88 , pp. 77-84
    • Kawagoe, J.1    Takizawa, T.2    Matsumoto, J.3
  • 13
    • 0036840959 scopus 로고    scopus 로고
    • Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway
    • Schmidlin F, Amadesi S, Dabbagh K et al. Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway. J. Immunol. 2002;169:5315-5321.
    • (2002) J. Immunol. , vol.169 , pp. 5315-5321
    • Schmidlin, F.1    Amadesi, S.2    Dabbagh, K.3
  • 15
    • 0032968706 scopus 로고    scopus 로고
    • Immunologic basis of antigen-induced airway hyperresponsiveness
    • Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu. Rev. Immunol. 1999;17:255-281.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 255-281
    • Wills-Karp, M.1
  • 16
    • 0032725001 scopus 로고    scopus 로고
    • The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: More similarities than differences
    • Humbert M, Menz G, Ying S et al. The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences. Immunol. Today 1999;20:528-533.
    • (1999) Immunol. Today , vol.20 , pp. 528-533
    • Humbert, M.1    Menz, G.2    Ying, S.3
  • 17
    • 0035184146 scopus 로고    scopus 로고
    • Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma
    • Knight DA, Lim S, Scaffidi AK et al. Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma. J. Allergy Clin. Immunol. 2001;108:797-803.
    • (2001) J. Allergy Clin. Immunol. , vol.108 , pp. 797-803
    • Knight, D.A.1    Lim, S.2    Scaffidi, A.K.3
  • 18
    • 0030689729 scopus 로고    scopus 로고
    • Induction of airway mucus production by T helper 2 (Th2) cells: A critical role for interleukin 4 in cell recruitment but not mucus production
    • Cohn L, Homer RJ, Marinov A, Rankin J, Bottomly K. Induction of airway mucus production by T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J. Exp. Med. 1997;186:1737-1747.
    • (1997) J. Exp. Med. , vol.186 , pp. 1737-1747
    • Cohn, L.1    Homer, R.J.2    Marinov, A.3    Rankin, J.4    Bottomly, K.5
  • 20
    • 0035070195 scopus 로고    scopus 로고
    • Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets
    • Grogan JL, Mohrs M, Harmon B, Lacy DA, Sedat JW, Locksley RM. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity 2001;14:205-215.
    • (2001) Immunity , vol.14 , pp. 205-215
    • Grogan, J.L.1    Mohrs, M.2    Harmon, B.3    Lacy, D.A.4    Sedat, J.W.5    Locksley, R.M.6
  • 21
    • 14844290334 scopus 로고    scopus 로고
    • Protease-activated receptor 2 activation in the airways enhances antigen-mediated airway inflammation and airway hyperresponsiveness through different pathways
    • Ebeling C, Forsythe P, Ng J et al. Protease-activated receptor 2 activation in the airways enhances antigen-mediated airway inflammation and airway hyperresponsiveness through different pathways. J. Allergy Clin. Immunol. 2005;115:623-630.
    • (2005) J. Allergy Clin. Immunol. , vol.115 , pp. 623-630
    • Ebeling, C.1    Forsythe, P.2    Ng, J.3
  • 22
    • 20444383923 scopus 로고    scopus 로고
    • Abrogation of bronchial eosinophilic inflammation and attenuated eotaxin content in protease-activated receptor 2-deficient mice
    • Takizawa T, Tamiya M, Hara T et al. Abrogation of bronchial eosinophilic inflammation and attenuated eotaxin content in protease-activated receptor 2-deficient mice. J. Pharmacol. Sci. 2005;98:99-102.
    • (2005) J. Pharmacol. Sci. , vol.98 , pp. 99-102
    • Takizawa, T.1    Tamiya, M.2    Hara, T.3
  • 23
    • 0037247658 scopus 로고    scopus 로고
    • Essential role for protease-activated receptor-2 in arthritis
    • Ferrell WR, Lockhart JC, Kelso EB et al. Essential role for protease-activated receptor-2 in arthritis. J. Clin. Invest. 2003;111:35-41.
    • (2003) J. Clin. Invest. , vol.111 , pp. 35-41
    • Ferrell, W.R.1    Lockhart, J.C.2    Kelso, E.B.3
  • 24
    • 0030961012 scopus 로고    scopus 로고
    • Functional interactions between the thrombin receptor and the T-cell antigen receptor in human T-cell lines
    • Joyce DE, Chen Y, Erger RA, Koretzky GA, Lentz SR. Functional interactions between the thrombin receptor and the T-cell antigen receptor in human T-cell lines. Blood 1997;90:1893-1901.
    • (1997) Blood , vol.90 , pp. 1893-1901
    • Joyce, D.E.1    Chen, Y.2    Erger, R.A.3    Koretzky, G.A.4    Lentz, S.R.5
  • 25
    • 0036164574 scopus 로고    scopus 로고
    • Signalling pathways induced by protease-activated receptors and integrins in T cells
    • Bar-Shavit R, Maoz M, Yongjun Y, Groysman M, Dekel I, Katzav S. Signalling pathways induced by protease-activated receptors and integrins in T cells. Immunology 2002;105:35-46.
    • (2002) Immunology , vol.105 , pp. 35-46
    • Bar-Shavit, R.1    Maoz, M.2    Yongjun, Y.3    Groysman, M.4    Dekel, I.5    Katzav, S.6


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